[en] We report the case of a late stillbirth which unexpectedly occurred in a patient without any medical history and after a meticulous obstetrical follow up. Stillbirth is unfortunately not unusual and implies a complete etiological work up. In the present observation, the Kleihauer test and anatomoclinical examination concluded that the death was due to an acute cerebral anoxy resulting from a massive fetomaternal hemorrhage (HFM). HFM is rarely considered as the cause of a late stillbirth, but its occurrence is certainly underestimated. Yet, if HFM is identified before fetal death, an .adequate management could considerably improve the fetal prognosis and, sometines, save the child's life.
Disciplines :
Reproductive medicine (gynecology, andrology, obstetrics)
Author, co-author :
Denef, Marie ; Centre Hospitalier Universitaire de Liège - CHU > > Service de gynécologie-obstétrique (CHR)
Capelle, Xavier ; Centre Hospitalier Universitaire de Liège - CHU > > Service de gynécologie-obstétrique
Van Linthout, Christine ; Centre Hospitalier Universitaire de Liège - CHU > > Service de gynécologie-obstétrique
LEPAGE, Sylvie ; Centre Hospitalier Universitaire de Liège - CHU > > Service de gynécologie-obstétrique
Emonts, Patrick ; Centre Hospitalier Universitaire de Liège - CHU > > Service de gynécologie-obstétrique (CHR)
Language :
French
Title :
LE CAS CLINIQUE DU MOIS. Mort foetale in utero due à une hémorragie foeto-maternelle massive.
Alternative titles :
[en] A case of fetal death resulting from a massive fetomaternal hemorrhage.
World Health Organization. - Definitions and indicators in family planning. Maternal & Child Health and Reproductive Health. Geneva. WHO Press, 2001.
MacDorman MF, Kirmeyer S. - Fetal and perinatal mortality, United States, 2005. Natl Vital Stat Rep, 2009, 57, 1-19.
Lewin F, Junger M, Dumont A. - Mort fœtale in utero, Traité d'Obstétrique. Médecine-sciences, Flammarion, 2003, 353-358.
Fretts EC. - ACOG Practice Bulletin No 102 : Management of stillbirth. Obstet Gynecol, 2009, 113, 748-751.
Lo YM, Lau TK, Chan LY, et al. - Quantitative analysis of the bidirectional fetomaternal transfer of nucleated cells and plasma DNA. Clin Chem, 2000, 46, 1301-1309.
de Almeida V, Bowman JM. - Massive fetomaternal hemorrhage : Manitoba experience. Obstet Gynecol, 1994, 83, 323-328.
Giacoia GP. - Severe fetomaternal hemorrhage : a review. Obstet Gynecol Surv, 1997, 52, 372-380.
Devi B, Jennison RF, Langley FA. - Signifiance of placental pathology in transplacental haemorrhage. J Clin Pathol, 1968, 21, 3223-3231.
Fisher R, Kuhnman K, Grover J, et al. - Chronic massive fetomaternal hemorrhage treated with repeated fetal intravascular transfusion. Am J Obstet Gynecol, 1990, 162, 203-204.
Rubod C,Mubaiayi N, Le Goueff F, et al. - Macrotransfusion fœto-maternelle spontanée révélée par une diminution de la perception des mouvements actifs fœtaux. J Gynecol Obstet Biol Reprod, 2004, 33, 241-244.
Boudier E, Langer B, Martinez C, et al. - La macrotransfusion foeto-maternelle. A propos de 3 cas avec revue de la littérature, J Gynecol Obstet Biol Reprod, 1999, 28, 456-462.
Rubod C, Houfflin V, Belot F, et al. - Successful in utero treatment of chronic and massive fetomaternal hemorrhage with fetal hydrops. Fetal DiagnTher, 2006, 21, 410-413.
Catalano PM, Capeless EL. - Fetomaternal bleeding as a cause of recurrent fetal morbidity and mortality. Obstet Gynecol, 1990, 76, 972-973.
Maass B, Würfel B, Fusch C. - Recurrent fetomaternal transfusion in two consecutive pregnancies. Prenat Diagn, 2001, 21, 791-793.
