Multicellular complexes of thymocytes and different types of thymic stromal cells in the mouse.

Microbial Collagenase; Animals; Cell Separation; Epithelium/ultrastructure; Female; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Thymus Gland/cytology; Thymus Gland/ultrastructure; Mouse; Nonlymphoid thymic cells; Thymic cell complexes; Thymus; Pathology and Forensic Medicine; Histology; Cell Biology

Abstract :

[en] The isolation of multicellular complexes of thymocytes and different types of thymic stromal cells from the mouse thymus is described. Isolated complexes were examined by light microscopy. Stromal cells, binding thymocytes at their surface, were identified using electron microscopy, and three types of epithelial cells, macrophages and interdigitating-like cells (IDC-like cells) were distinguished from their morphological characteristics. The epithelial cell types correspond morphologically to epithelial cells present in situ in various thymic regions. The type of thymocyte-contact with epithelial cells, macrophages and IDC-like cells indicated that the formation of multicellular complexes is common.

Disciplines :

Anatomy (cytology, histology, embryology...) & physiology

Author, co-author :

Brelińska, Renata; Laboratory of Pathological Anatomy, University of Liege, Liege, Belgium

Defresne, Marie-Paule ; Université de Liège - ULiège > Département des sciences précliniques MI > Anatomie et cytologie pathologiques

Boniver, Jacques ; Centre Hospitalier Universitaire de Liège - CHU > > Autres services administratifs

Language :

English

Title :

Multicellular complexes of thymocytes and different types of thymic stromal cells in the mouse.

Publication date :

1986

Journal title :

Cell and Tissue Research

ISSN :

0302-766X

eISSN :

1432-0878

Publisher :

Springer-Verlag, Germany

Volume :

244

Issue :

Pages :

673 - 679

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://link.springer.com/content/pdf/10.1007/BF00212548.pdf

Funders :

FRSM - Fonds de la Recherche Scientifique Médicale
CAC - Centre anticancéreux près l'Université de Liège asbl
PAN - Polish Academy of Sciences

Available on ORBi :

since 24 June 2023

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Bibliography

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