Fu J.Y., Masferrer J.L., Seibert K., Raz A., Needleman P. (1990) The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 265:16737-16740.
Funk C.D., Funk L.B., Kennedy M.E., Pong A.S., Fitzgerald G.A. (1991) Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. FASEB J 5:2304-2312.
Goppelt-Struebe M. (1995) Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression. Prostaglandins, Leukot Essent Fatty Acids 52:213-222.
Smith W.L., Meade E.A., DeWitt D. (1994) L. interactions of PGH synthase isozymes-1 and -2 with NSAIDs. Ann N Y Acad Sci 744:50-57.
Masferrer J.L., Zweifel B.S., Manning P.T. (1994) Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci U.S.A. 91:3228-3232.
Komhoff M., Grone H.J., Klein T., Seyberth H.W., Nusing R.M. (1997) Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: Implication for renal function. Am J Physiol 272.
Khan K.N., Venturini C.M., Bunch R.T., Brassard J.A., Koki A.T., Morris D.L., Trump B.F., Maziasz T.J., Alden C.L. (1998) Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity. Toxicol Pathol 26:612-620.
Crofford L.J. (1997) COX-1 and COX-2 tissue expression: Implications and predictions. J Rheumatol 24.
Arakawa T., Higuchi K., Fukuda T., Fujiwara Y., Kobayashi K., Kuroki T. (1998) Prostaglandins in the stomach: An update. J Clin Gastroenterol 27.
Crofford L.J. (1997) COX-1 and COX-2 tissue expression: Implications and predictions. J Rheumatol 24.
Vane J.R., Bakhle Y.S., Botting R.M. (1998) Cyclooxygenase 1 and 2. Annu Rev Pharmacol Toxicol 38:97-120.
Coffey R.J., Hawkey C.J., Damstrup L., Graves-Deal R., Daniel V.C., Dempsey P.J., Chinery R., Kirkland S.C., DuBois R.N., Jetton T.L., Morrow J.D. (1997) Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. Proc Natl Acad Sci USA 94:657-662.
Sheng H., Shao J., Dixon D.A., Williams C.S., Prescott S.M., Dubois R.N., Beauchamp R.D. (2000) Transforming growth factor-beta 1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA. J Biol Chem 275:6628-6635.
Crofford L.J., Wilder R.L., Ristimaki A.P., Sano H., Remmers E.F., Epps H.R., Hla T. (1994) Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. J Clin Invest 93:1095-1101.
Ristimaki A., Garfinkel S., Wessendorf J., Maciag T., Hla T. (1994) Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation. J Biol Chem 269:11769-11775.
Noguchi K., Shitashige M., Yanai M., Morita I., Nishihara T., Murota S., Ishikawa I. (1996) Prostaglandin production via induction of cyclooxygenase-2 by human gingival fibroblasts stimulated with lipopolysaccharides. Inflammation 20:555-568.
Hwang D., Jang B.C., Yu G., Boudreau M. (1997) Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: Mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages. Biochem Pharmacol 54:87-96.
Goppelt-Struebe M., Beiche F. (1997) Cyclooxygenase-2 in the spinal cord: Localization and regulation after a peripheral inflammatory stimulus. Adv Exp Med Biol 433:213-216.
Tucker O.N., Dannenberg A.J., Yang E.K., Zhang F., Teng L., Daly J.M., Soslow R.A., Masferrer J.L., Woerner B.M., Koki A.T., Fahey T.J. (1999) 3rd cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer. Res. 59:987-990.
Wolff H., Saukkonen K., Anttila S., Karjalainen A., Vainio H., Ristimaki A. (1998) Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res. 58:4997-5001.
Achiwa H., Yatabe Y., Hida T., Kuroishi T., Kozaki K., Nakamura S., Ogawa M., Sugiura T., Mitsudomi T., Takahashi T. (1999) Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas. Clin Cancer Res 5:1001-1005.
Shiota G., Okubo M., Noumi T., Noguchi N., Oyama K., Takano Y., Yashima K., Kishimoto Y., Kawasaki H. (1999) Cyclooxygenase-2 expression in hepatocellular carcinoma. Hepatogastroenterology 46:407-412.
Dubois R.N., Giardiello F.M., Smalley W.E. (1996) Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention. Gastroenterol Clin North Am 25:773-791.
Smalley W., Ray W.A., Daugherty J., Griffin M.R. (1999) Use of nonsteroidal anti-inflammatory drugs and incidence of colorectal cancer: A population-based study. Arch Intern Med 159:161-166.
Dearden J.C., Nicholson R.M. (1984) Correlation between gastric irritancy and anti-inflammatory activity of non-steroidal anti-inflammatory drugs. J Pharm Pharmac 36:713-715.
Mitchell J.A., Akarasereenont P., Thiemermann C., Flower R.J., Vane J.R. (1994) Selectivity of non steroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 90:11693-11697.
Patrignani P., Panara M.R., Greco A., Fusco O., Natoli C., Iacobelli S., Cipollone F., Ganci A., Creminon C., Maclouf J. (1994) Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. J Pharmacol Exp Ther 271:1705-1712.
Nantel F., Denis D., Gordon R., Nortjhey A., Cirino M., Metters K.M., Chan C.C. (1999) Distribution and regulation of cyclooxygenase-2 in carrageenan-induced inflammation. Br J Pharmacol 128:853-859.
Serteyn D., Deby-Dupont G., Pincemail J., Mottard E., Phillipart C., Lamy M. (1988) Equine post-anesthesic myositis: Thromboxane, prostacyclin and prostaglandin E2 production. Vet Res Comm 12:219-226.
Smith W.L., Garavito R.M., DeWitt D.L. (1996) Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem 271:33157-33160.
Yamazaki R., Kawai S., Matsumoto T., Matsuzaki T., Hashimoto S., Yokokura T., Okamoto R., Koshino T., Mizushima Y. (1999) Hydrolytic activity is essential for aceclofenac to inhibit cyclooxygeanse in rheumatoid synovial cells. J Pharmacol Exp Ther 289:676-681.
Ferreira S.H. (1993) The role of interleukins and nitric oxide in the mediation of inflammatory pain and its control by peripheral analgesics. Drugs 46.
Ottonello L., Dapino P., Pastorino G., Montagnani G., Gatti F., Guidi G. (1993) Nimesulide as a down regulator of the activity of the neutrophil myeloperoxidase pathway: Focus on the histoprotective potential of the drug during inflammatory processes. Drugs 46.
Griswold D.E., Adams J.L. (1996) Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): Rationale for selective inhibition had progress to date. Med Res Rev 16:181-206.