[en] In contrast to a recent study reporting an unexpected significant difference for total 25-hydroxyvitamin D (25(OH)D) between serum and EDTA plasma, we demonstrate that concentrations of total 25(OH)D, 25(OH)D2, 25(OH)D3 and 24,25(OH)2D3 do not differ between matched serum and EDTA plasma samples, using two well-characterized LC-MS/MS methods.
Disciplines :
Laboratory medicine & medical technology
Author, co-author :
van der Vorm, Lisa N; Department of Clinical Chemistry, Central Diagnostic Laboratory, Amsterdam University Medical Center, Amsterdam, the Netherlands
Le Goff, Caroline ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chimie clinique
PEETERS, Stéphanie ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chimie clinique
Makris, Konstantinos; Clinical Biochemistry Department, KAT General Hospital, Athens, Greece, Laboratory for Research of the Musculoskeletal System "Th. Garofalidis", Medical School, University of Athens, Athens, Greece
Cavalier, Etienne ; Centre Hospitalier Universitaire de Liège - CHU > > Service de chimie clinique
Heijboer, Annemieke C; Department of Clinical Chemistry, Endocrine Laboratory, Amsterdam Gastroenterology Endocrinology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: a.heijboer@amsterdamumc.nl
Language :
English
Title :
25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma.
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