Article (Scientific journals)
Melanin-concentrating hormone and immune function
Lakaye, Bernard; Coumans, Bernard; Harray, Sophie et al.
2009In Peptides, 30, p. 2076-80
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Abstract :
[en] To date,melanin-concentrating hormone (MCH) has been generally considered as peptide acting almost exclusively in the central nervous system. In the present paper, we revise the experimental evidence, demonstrating that MCH and its receptors are expressed by cells of the immune system and directly influence the response of these cells in some circumstances. This therefore supports the idea that, as with other peptides, MCH could be considered as a modulator of the immune system. Moreover, we suggest that this could have important implications in several immune-mediated disorders and affirm that there is a clear need for further investigation
Disciplines :
Immunology & infectious disease
Author, co-author :
Lakaye, Bernard ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie humaine et pathologique
Coumans, Bernard ;  Université de Liège - ULiège > CNCM/ Centre fac. de rech. en neurobiologie cell. et moléc.
Harray, Sophie ;  Université de Liège - ULiège > CNCM/ Centre fac. de rech. en neurobiologie cell. et moléc.
Grisar, Thierry ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie humaine et pathologique
Language :
English
Title :
Melanin-concentrating hormone and immune function
Publication date :
2009
Journal title :
Peptides
ISSN :
0196-9781
eISSN :
1873-5169
Publisher :
Elsevier Science, New York, United States - New York
Volume :
30
Pages :
2076-80
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 05 November 2009

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