Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique. |
Seutin, V., WANG, F.-C., Lakaye, B., & Hansen, I. (17 December 2022). Les syndromes myasthéniques et myotoniques congénitaux: rencontre des sciences fondamentales et des sciences cliniques [Paper presentation]. Datablitz du service de neurologie du CHU de Liège, Liège, Belgium. |
Jehasse, K., Massotte, L., Hartmann, S., Vitello, R., Ringlet, S., Vitello, M., Chua, H. C., Pless, S., Engel, D., Liégeois, J.-F., Lakaye, B., Roeper, J., & Seutin, V. (01 October 2021). The gating pore blocker 1-(2,4-xylyl)guanidinium selectively inhibits pacemaking of midbrain dopaminergic neurons. Neuropharmacology, 197, 1-15. doi:10.1016/j.neuropharm.2021.108722 Peer Reviewed verified by ORBi |
Jehasse, K., Jacquerie, K., de Froidmont, A., Lemoine, C., Grisar, T., Stouffs, K., Lakaye, B., & Seutin, V. (2021). Functional analysis of the F337C mutation in the CLCN1 gene associated with dominant myotonia congenita reveals an alteration of the macroscopic conductance and voltage dependence. Molecular Genetics and Genomic Medicine, 1588. doi:10.1002/mgg3.1588 Peer Reviewed verified by ORBi |
Jehasse, K., Massotte, L., Hartmann, S., Vitello, R., Ringlet, S., Lakaye, B., Liégeois, J.-F., Roeper, J., & Seutin, V. (22 May 2020). On the path to understanding pacemaking of dopaminergic neurons [Poster presentation]. Virtual Dopamine Meeting. |
Sambon, M., Gorlova, A., Demelenne, A., Alhama-Riba, J., Coumans, B., Lakaye, B., Wins, P., Fillet, M., Anthony, D. C., Strekalova, T., & Bettendorff, L. (2020). Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration. Biomedicines, 8, 361. doi:10.3390/biomedicines8090361 Peer Reviewed verified by ORBi |
Gilsoul, M., Grisar, T., Delgado-Escueta, A. V., de Nijs, L., & Lakaye, B. (27 September 2019). Subtle brain developmental abnormalities in the pathogenesis of juvenile myoclonic epilepsy. Frontiers in Cellular Neuroscience, 13, 433. doi:10.3389/fncel.2019.00433 Peer Reviewed verified by ORBi |
Gilsoul, M., Medard, L., Coumans, B., Delgado-Escueta, A., de Nijs, L., & Lakaye, B. (July 2018). EFHC1, a protein mutated in Juvenile Myoclonic Epilepsy, interacts with TTLL6 and modulates the level of tubulin polyglutamylation [Poster presentation]. FENS - 11th edition, Berlin, Germany. |
Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., ... Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express. |
bailey, J., de Nijs, L., Bai, D., Suzuki, T., Miyamoto, H., Tanaka, M., Patterson, C., Lin, Y.-C., Medina, M., Alonso, M., Serratosa, J., Duron, R., Nguyen, V., Wight, J., Martinez-Juarez, I., Ochoa, A., Jara-Prado, A., Guilhoto, L., Molina, Y., ... Delgado-Escueta*. (March 2018). Variant intestinal-cell kinase in juvenile myoclonic epilepsy. New England Journal of Medicine, 378, 1018-28. doi:10.1056/NEJMoa1700175 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Nganou, G., Gomes Da Silva, C., Gladwyn-Ng, I., Engel, D., Coumans, B., Delgado-Escueta, A. V., Tanaka, M., Nguyen, L., Grisar, T., de Nijs, L., & Lakaye, B. (2018). Importin-8 Modulates Division of Apical Progenitors, Dendritogenesis and Tangential Migration During Development of Mouse Cortex. Frontiers in Molecular Neuroscience, 11, 234. doi:10.3389/fnmol.2018.00234 Peer Reviewed verified by ORBi |
Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique. |
Nganou, G., Tanaka, M., Coumans, B. (Other coll.), Gomes Da Silva, C. (Other coll.), Grisar, T. (Other coll.), De Nijs, L. (Other coll.), Delgado Escueta, A. V. (Other coll.), & Lakaye, B. (Other coll.). (27 April 2017). Importin-8 could cause CAE/JME by delaying early neuroblast migration [Poster presentation]. 2nd Joint SFBD/SBCF Meeting : When Development meets Cell Biology, Lyon, France. |
Vignisse, J., Sambon, M., Gorlova, A., Pavlov, D., Caron, N., Malgrange, B., Shevtsova, E., Svistunov, A., Anthony, D. C., Markova, N., Bazhenova, N., Coumans, B., Lakaye, B., Wins, P., Strekalova, T., & Bettendorff, L. (2017). Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels. Molecular and Cellular Neuroscience, 82, 126-136. doi:10.1016/j.mcn.2017.05.005 Peer Reviewed verified by ORBi |
Bailey, J.* , Patterson, C.* , de Nijs, L., Duron, R., Ngyen, V., Tanaka, M., Medina, M., Jara-Prado, A., Martinez-Juarez, I., Ochoa, A., Molina, Y., Suzuki, T., Alonso, M., Wight, J., Lin, Y., Guilhoto, L., Yacubian, E., Machado-Salas, J., Daga, A., ... Delgado-Escueta, A. (2017). EFHC1 variants in juvenile myoclonic epilepsy: reanalysis according to NHGRI and ACMG guidelines for assigning disease causality. Genetics in Medicine, 19, 144-156. doi:10.1038/gim.2016.86 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Nganou, G., Coumans, B., De Nijs, L., & Lakaye, B. (06 December 2016). Implication of Importin-8 in mouse brain development [Poster presentation]. American Society for Cell Biology, San Francisco, United States. |
Nganou, G., Tanaka, M., Coumans, B., GRISAR, T., De Nijs, L., Delgado-Escueta, A., & Lakaye, B. (December 2016). Importin-8 mutations could cause Jeavons Syndrome, CAE and JME by altering early neuroblast migration [Poster presentation]. American Epilepsy Society, Houston (TEXAS), United States. |
Nganou, G., Denijs, L., Lakaye, B., & Coumans, B. (Other coll.). (08 October 2016). Implication of Importin-8 in mouse brain development [Poster presentation]. 6th Belgian Brain Congress, Mons, Belgium. doi:10.3389/conf.fnagi.2016.03.00037 |
Medard, L., Coumans, B., Lakaye, B., De Nijs, L., & Godin, J. (Other coll.). (June 2016). Myoclonin-1 modulates the post-translational modification of microtubules [Poster presentation]. EMBO | EMBL Symposium: Microtubules: From Atoms to Complex Systems, Heidelberg, Germany. |
Medard, L., Godin, J. (Other coll.), Coumans, B. (Other coll.), GRISAR, T. (Other coll.), Delgado-Escueta, A. (Other coll.), Lakaye, B. (Other coll.), & de Nijs, L. (Other coll.). (December 2015). EFHC1/Myoclonin-1 modulates the post-translational modification of microtubules [Poster presentation]. 69th Annual Meeting American Epilepsy Society, Philadelphie, United States. |
Medard, L., Lakaye, B., Godin, J. (Other coll.), Coumans, B. (Other coll.), & de Nijs, L. (Other coll.). (2015). Myoclonin 1 modulates the post-translational modification of microtubules [Poster presentation]. BSCDB SPRING MEETING 2015, Liège, Belgium. |
Bettendorff, L., Lakaye, B., Kohn, G., & Wins, P. (25 May 2014). In search of a physiological role for thiamine triphosphate and the 25-kDa thiamine triphosphatase [Paper presentation]. 8th International Conference on Thiamine: From Catalysis to Pathology, Liège, Belgium. |
Kohn, G., Ectors, F., Lakaye, B., & Bettendorff, L. (May 2014). 25KDa-Thiamine triphosphatase is essential for spermatozoid development in mice [Poster presentation]. 8th International Conference on Thiamine: From Catalysis to Pathology, Liège, Belgium. |
Geuzaine, A., Tyhon, A., Grisar, T., Brabant, C., Lakaye, B.* , & Tirelli, E.*. (2014). Amphetamine reward in food restricted mice lacking the melanin-concentrating hormone receptor-1. Behavioural Brain Research, 262, 14-20. doi:10.1016/j.bbr.2013.12.052 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
de Nijs, L., Wolkoff, N., Grisar, T., & Lakaye, B. (2013). Juvenile myoclonic epilepsy as a possible neurodevelopmental disease: role of EFHC1 or Myoclonin 1. Epilepsy and Behavior, 28, 58-S60. Peer Reviewed verified by ORBi |
Conductier, G., Brau, F., Viola, A., Langlet, F., Ramkumar, N., Dehouck, B., Lemaire, T., Chapot, R., Lucas, L., Rovère, C., Maître, P., Hosseiny, S., Petit-Paitel, A., Adamantidis, A., Lakaye, B., Risold, P., Prevot, V., Meste, O., Nahon, J., & Guyon, A. (2013). Melanin-concentrating hormone regulates beat frequency of ependymal cilia and ventricular volume. Nature Neuroscience, 16, 845-847. doi:10.1038/nn.3401 Peer Reviewed verified by ORBi |
Delvaux, D., Kerff, F., Murty, M. R. V. S., Lakaye, B., Czerniecki, J., Kohn, G., Wins, P., Herman, R., Gabelica, V., Heuze, F., Tordoir, X., Marée, R., Matagne, A., Charlier, P., De Pauw, E., & Bettendorff, L. (2013). Structural Determinants of Specificity and Catalytic Mechanism in mammalian 25-kDa Thiamine Triphosphatase. Biochimica et Biophysica Acta - General Subjects, 1830, 4513-4523. doi:10.1016/j.bbagen.2013.05.014 Peer Reviewed verified by ORBi |
Gigliobianco, T., GANGOLF, M., Lakaye, B., Pirson, B., von Ballmoos, C., Wins, P., & Bettendorff, L. (January 2013). An alternative role of FoF1-ATP synthase in Escherichia coli: synthesis of thiamine triphosphate. Scientific Reports, 3 (1071). doi:10.1038/srep01071 Peer Reviewed verified by ORBi |
Kohn, G., Delvaux, D., Lakaye, B., Servais, A.-C., Scholer, G., Fillet, M., Elias, B., Derochette, J.-M., Crommen, J., Wins, P., & Bettendorff, L. (12 September 2012). High inorganic triphosphatase activities in bacteria and mammalian cells: Identification of the enzymes involved. PLoS ONE, 7 (9), 43879. doi:10.1371/journal.pone.0043879 Peer Reviewed verified by ORBi |
de Nijs, L., Wolkoff, N., Coumans, B., Delgado-Escueta, A., Grisar, T., & Lakaye, B. (2012). Mutations of EFHC1, linked to juvenile myoclonic epilepsy, disrupt radial and tangential migrations during brain development. Human Molecular Genetics, 21 (23), 5106-17. doi:10.1093/hmg/dds356 Peer Reviewed verified by ORBi |
Bettendorff, L., Delvaux, D., Kohn, G., Wins, P., & Lakaye, B. (2012). Molecular evolution of the CYTH superfamily of proteins [Poster presentation]. 22nd IUBMB & 37th FEBS Congress, Seville, Spain, September 4-9, 2012, Sevilla, Spain. |
Grisar, T., Lakaye, B., de Nijs, L., LoTurco, J., Daga, A., & Delgado-Escueta, A. (2012). Myoclonin1/EFHC1 in cell division, neuroblast migration, synapse/dendrite formation in juvenile myoclonic epilepsy. In J. Noebels, M. Avoli, M. Rogawski, R. Olsen, ... A. Delgado-Escueta (Eds.), Jasper's Basic Mechanisms of the Epilepsies, 4th edition (National Center for Biotechnology Information, pp. 1-19). Bethesda (MD), United States: NCBI. Peer reviewed |
Sherwood, A., Wosiki-Kuhn, M., Nguyen, T., Holland, P., Lakaye, B., Adamantidis, A., & Johnson, A. (2012). The role of melanin-concentrating hormone in conditioned reward learning. European Journal of Neuroscience, 36, 3126-33. doi:10.1111/j.1460-9568.2012.08207.x Peer Reviewed verified by ORBi |
Delvaux, D., Murty, M. R. V. S., Gabelica, V., Lakaye, B., Lunin, V. V., Skarina, T., Onopriyenko, O., Kohn, G., Wins, P., De Pauw, E., & Bettendorff, L. (2011). A specific inorganic triphosphatase from Nitrosomonas europaea: structure and catalytic mechanism. Journal of Biological Chemistry, 286, 34023-34035. doi:10.1074/jbc.M111.233585 Peer Reviewed verified by ORBi |
Gangolf, M., Czerniecki, J., Radermecker, M., Detry, O., NISOLLE, M., JOUAN, C., Martin, D., Chantraine, F., Lakaye, B., Wins, P., Grisar, T., & Bettendorff, L. (October 2010). Thiamine Status in Humans and Content of Phosphorylated Thiamine Derivatives in Biopsies and Cultured Cells. PLoS ONE, 5 (10), 13616. doi:10.1371/journal.pone.0013616 Peer Reviewed verified by ORBi |
Gigliobianco, T., Lakaye, B., Wins, P., Elmoualij, B., Zorzi, W., & Bettendorff, L. (May 2010). Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. BMC Microbiology, 10, 148. doi:10.1186/1471-2180-10-148 Peer Reviewed verified by ORBi |
Leon, C., de Nijs, L., Chanas, G., Delgado-Escueta, A. V., Grisar, T., & Lakaye, B. (2010). Distribution of EFHC1 or myoclonin 1 in mouse neural structures. Epilepsy Research, 88, 196-207. doi:10.1016/j.eplepsyres.2009.11.009 Peer Reviewed verified by ORBi |
Wortge, S., Eshkind, L., Cabezas-Wallscheid, N., Lakaye, B., Kim, J., Heck, R., Abassi, Y., Diken, M., Sprengel, R., & Bockamp, E. (2010). Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression. BMC Developmental Biology, 10, 95. doi:10.1186/1471-213X-10-95 Peer Reviewed verified by ORBi |
Pachoud, B., Adamantidis, A., Ravassard, P., Luppi, P.-H., Grisar, T., Lakaye, B., & Salin, P.-A. (2010). Major impairments of glutamatergic transmission and long term synaptic plasticity in the hippocampus of mice lacking the melanin-concentrating hormone receptor-1. Journal of Neurophysiology, 104, 1417-1425. doi:10.1152/jn.01052.2009 Peer Reviewed verified by ORBi |
Didone, V., Tirelli, E., Quertemont, E., & Lakaye, B. (2010). Ethanol-induced behaviors in mice genetically deficient in MCH1 receptors. Alcoholism, Clinical and Experimental Research, 34 (8), 93A-93. |
Lakaye, B., de Nijs, L., Leon, C., & Grisar, T. (2009). Cytoskeletal genes and idiopathic epilepsies. In A. Schwartzkroin (Ed.), Encyclopedia of Basic Epilepsy Research (pp. 323-329). Oxford Academic Press. |
Lakaye, B., Coumans, B., Harray, S., & Grisar, T. (2009). Melanin-concentrating hormone and immune function. Peptides, 30, 2076-80. doi:10.1016/j.peptides.2009.05.004 Peer Reviewed verified by ORBi |
de Nijs, L., Leon, C., Nguyen, L., LoTurco, J. J., Delgado-Escueta, A. V., Grisar, T., & Lakaye, B. (2009). EFHC1 interacts with microtubules to regulate cell division and cortical development. Nature Neuroscience, 12 (10), 1266-74. doi:10.1038/nn.2390 Peer Reviewed verified by ORBi |
Brabant, C., Alleva, L., Grisar, T., Quertemont, E., Lakaye, B., Ohtsu, H., Lin, J.-S., Jatlow, P., Picciotto, M. R., & Tirelli, E. (2009). Effects of the H(3) receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions. Psychopharmacology, 202 (4), 673-87. doi:10.1007/s00213-008-1345-y Peer Reviewed verified by ORBi |
Gigliobianco, T., Lakaye, B., Makarchikov, A. F., Wins, P., & Bettendorff, L. (2008). Adenylate Kinase-Independent Thiamine Triphosphate Accumulation under Severe Energy Stress in Escherichia Coli. BMC Microbiology, 8, 16. doi:10.1186/1471-2180-8-16 Peer Reviewed verified by ORBi |
Adamantidis, A., Salvert, D., Goutagny, R., Lakaye, B., Gervasconi, D., Grisar, T., Luppi, P. H., & Fort, P. (2008). Sleep architecture of the melanin-concentrating hormone receptor 1-knockout mice. European Journal of Neuroscience, 27 (7), 1793-800. doi:10.1111/j.1460-9568.2008.06129.x Peer Reviewed verified by ORBi |
Tyhon, A.* , Lakaye, B.* , Grisar, T., & Tirelli, E. (2008). Deletion of Melanin-Concentrating Hormone Receptor-1 gene accentuates D-amphetamine-induced psychomotor activation but neither the subsequent development of sensitization nor the expression of conditioned activity in mice. Pharmacology, Biochemistry and Behavior, 88, 446-55. doi:10.1016/j.pbb.2007.10.001 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Tyhon, A.* , Lakaye, B.* , Adamantidis, A., & Tirelli, E. (2008). Amphetamine- and cocaine-induced conditioned place preference and concomitant psychomotor sensitization in mice with genetically inactivated melanin-concentrating hormone MCH(1) receptor. European Journal of Pharmacology, 599 (1-3), 72-80. doi:10.1016/j.ejphar.2008.09.027 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Coumans, B., Grisar, T., Nahon, J. L., & Lakaye, B. (04 October 2007). Effect of ppMCH derived peptides on PBMC proliferation and cytokine expression. Regulatory Peptides, 143 (1-3), 104-108. doi:10.1016/j.regpep.2007.04.001 Peer Reviewed verified by ORBi |
Duncan, E. A., Sorrell, J. E., Adamantidis, A., Rider, T., Jandacek, R. J., Seeley, R. J., Lakaye, B., & Woods, S. C. (August 2007). Alcohol drinking in MCH receptor-1-deficient mice. Alcoholism, Clinical and Experimental Research, 31 (8), 1325-1337. doi:10.1111/j.1530-0277.2007.00427.x Peer Reviewed verified by ORBi |
Tyhon, A., Adamantidis, A., Foidart, A., Grisar, T., Lakaye, B., & Tirelli, E. (02 October 2006). Mice lacking the melanin-concentrating hormone receptor-1 exhibit an atypical psychomotor susceptibility to cocaine and no conditioned cocaine response. Behavioural Brain Research, 173 (1), 94-103. doi:10.1016/j.bbr.2006.06.007 Peer Reviewed verified by ORBi |
de Nijs, L., Lakaye, B., Coumans, B., Leon, C., Ikeda, T., Delgado-Escueta, A. V., Grisar, T., & Chanas, G. (10 September 2006). EFHC1, a protein mutated in juvenile myoclonic epilepsy, associates with the mitotic spindle through its N-terminus. Experimental Cell Research, 312 (15), 2872-2879. doi:10.1016/j.yexcr.2006.05.011 Peer Reviewed verified by ORBi |
Grisar, T., de Nijs, L., Chanas, G., Leon, C., Coumans, B., Foidart, A., & Lakaye, B. (2006). Some genetic and biochemical aspects of myoclonus. Neurophysiologie Clinique, 36 (5-6, Sep-Dec), 271-279. doi:10.1016/j.neucli.2006.11.002 Peer Reviewed verified by ORBi |
Adamantidis, A., Thomas, E., Foidart, A., Tyhon, A., Coumans, B., Minet, A., Tirelli, E., Seutin, V., Grisar, T., & Lakaye, B. (15 November 2005). Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive and NMDA response deficit. Journal of the Neurological Sciences, 238 (Suppl. 1), 288. Peer Reviewed verified by ORBi |
Szyniarowski, P., Lakaye, B., Czerniecki, J., Makarchikov, A. F., Wins, P., Margineanu, I., Coumans, B., Grisar, T., & Bettendorff, L. (2005). Pig tissues express a catalytically inefficient 25-kDa thiamine triphosphatase: Insight in the catalytic mechanisms of this enzyme. Biochimica et Biophysica Acta - General Subjects, 1725 (1), 93-102. doi:10.1016/j.bbagen.2005.05.026 Peer Reviewed verified by ORBi |
Adamantidis, A., Thomas, E., Foidart, A., Tyhon, A., Coumans, B., Minet, A., Tirelli, E., Seutin, V., Grisar, T., & Lakaye, B. (2005). Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive deficits and alterations of NMDA receptor function. European Journal of Neuroscience, 21 (10), 2837-44. doi:10.1111/j.1460-9568.2005.04100.x Peer Reviewed verified by ORBi |
Lakaye, B., Adamantidis, A., Coumans, B., & Grisar, T. (16 April 2004). Promoter characterization of the mouse melanin-concentrating hormone receptor 1. Biochimica et Biophysica Acta-Gene Structure and Expression, 1678 (1), 1-6. doi:10.1016/j.bbaexp.2004.01.006 Peer Reviewed verified by ORBi |
Lakaye, B., Verlaet, M., Dubail, J., Czerniecki, J., Bontems, S., Makarchikov, A. F., Wins, P., Piette, J., Grisar, T., & Bettendorff, L. (2004). Expression of 25 kDa thiamine triphosphatase in rodent tissues using quantitative PCR and characterization of its mRNA. International Journal of Biochemistry and Cell Biology, 36 (10), 2032-2041. doi:10.1016/j.biocel.2004.03.004 Peer Reviewed verified by ORBi |
Lakaye, B., Wirtzfeld, B., Wins, P., Grisar, T., & Bettendorff, L. (2004). Thiamine triphosphate, a new signal required for optimal growth of Escherichia coli during amino acid starvation. Journal of Biological Chemistry, 279 (17), 17142-17147. doi:10.1074/jbc.M313569200 Peer Reviewed verified by ORBi |
Czerniecki, J., Chanas, G., Verlaet, M., Bettendorff, L., Makarchikov, A. F., Leprince, P., Wins, P., Grisar, T., & Lakaye, B. (2004). Neuronal localization of the 25-kDa specific thiamine triphosphatase in rodent brain. Neuroscience, 125 (4), 833-840. doi:10.1016/j.neuroscience.2004.02.033 Peer Reviewed verified by ORBi |
Lakaye, B., Makarchikov, A. F., Wins, P., Margineanu, I., Roland, S., Lins, L., Aichour, R., Lebeau, L., Elmoualij, B., Zorzi, W., Coumans, B., Grisar, T., & Bettendorff, L. (2004). Human recombinant thiamine triphosphatase: purification, secondary structure and catalytic properties. International Journal of Biochemistry and Cell Biology, 36 (7), 1348-1364. doi:10.1016/j.biocel.2003.11.013 Peer Reviewed verified by ORBi |
Bettendorff, L., Nghiem, H. O., Wins, P., & Lakaye, B. (2003). A general method for the chemical synthesis of gamma-P-32-labeled or unlabeled nucleoside 5 '-triphosphates and thiamine triphosphate. Analytical Biochemistry, 322 (2), 190-197. doi:10.1016/j.ab.2003.08.013 Peer Reviewed verified by ORBi |
Makarchikov, A. F., Lakaye, B., Gulyai, I. E., Czerniecki, J., Coumans, B., Wins, P., Grisar, T., & Bettendorff, L. (2003). Thiamine triphosphate and thiamine triphosphatase activities: from bacteria to mammals. Cellular and Molecular Life Sciences, 60 (7), 1477-1488. doi:10.1007/s00018-003-3098-4 Peer Reviewed verified by ORBi |
Ruelle, V., Zorzi, W., Elmoualij, B., Pierard, O., Heinen, E., Lakaye, B., Bettendorff, L., Rees, J., Voorhees, K., & De Pauw, E. (2003). Fingerprint matching of genetically modified E.coli strains by MALDI-TOF Mass Spectrometry of whole cells using a k-nearest-neighbors approach [Poster presentation]. 8th Conference on Food Microbiology. 19-20 Juin 2003. Liège – Belgique. |
Verlaet, M., Adamantidis, A., Coumans, B., Chanas, G., Zorzi, W., Heinen, E., Grisar, T., & Lakaye, B. (11 September 2002). Human immune cells express ppMCH mRNA and functional MCHR1 receptor. FEBS Letters, 527 (1-3), 205-210. doi:10.1016/S0014-5793(02)03232-5 Peer Reviewed verified by ORBi |
Lakaye, B., Dubus, A., Joris, B., & Frère, J.-M. (September 2002). Method for estimation of low outer membrane permeability to beta-lactam antibiotics. Antimicrobial Agents and Chemotherapy, 46 (9), 2901-2907. doi:10.1128/AAC.46.9.2901-2907.2002 Peer Reviewed verified by ORBi |
Lakaye, B., Thomas, E., Minet, A., & Grisar, T. (2002). The genetic absence epilepsy rat from Strasbourg (GAERS), a rat model of absence epilepsy: Computer modeling and differential gene expression. Epilepsia, 43 (Suppl. 5), 123-129. doi:10.1046/j.1528-1157.43.s.5.17.x Peer Reviewed verified by ORBi |
Bettendorff, L., Lakaye, B., Margineanu, I., Grisar, T., & Wins, P. (2002). ATP-driven, Na(+)-independent inward Cl- pumping in neuroblastoma cells. Journal of Neurochemistry, 81 (4), 792-801. doi:10.1046/j.1471-4159.2002.00858.x Peer Reviewed verified by ORBi |
Lakaye, B., Makarchikov, A. F., Antunes, A. F., Zorzi, W., Coumans, B., De Pauw, E., Wins, P., Grisar, T., & Bettendorff, L. (2002). Molecular characterization of a specific thiamine triphosphatase widely expressed in mammalian tissues. Journal of Biological Chemistry, 277 (16), 13771-13777. doi:10.1074/jbc.M111241200 Peer Reviewed verified by ORBi |
Ruelle, V., Zorzi, W., Elmoualij, B., Lakaye, B., Heinen, E., & De Pauw, E. (2002). Detection of minor variations between genetically modified and wild-type E.coli strains by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry of whole cells [Poster presentation]. Euroanalysis – European Conference on Analytical Chemistry. September 8-13, 2002. Dortmund – Germany. |
Charlier, T., Lakaye, B., Ball, G. F., & Balthazart, J. (2002). Steroid receptor coactivator SRC-1 exhibits high expression in steroid-sensitive brain areas regulating reproductive behaviors in the quail brain. Neuroendocrinology, 76 (5), 297-315. doi:10.1159/000066624 Peer Reviewed verified by ORBi |
Makarchikov, A. F., Luchko, A. A., Bettendorff, L., Lakaye, B., & Wins, P. (2002). Study of the role of ionogenic amino-acid residues in catalytic activity of thiamine triphosphatase from bovine kidney by means of chemical modification. News of Biomedical Sciences, 3, 66-70. Peer reviewed |
Charlier, T., Lakaye, B., Ball, G. F., & Balthazart, J. (2001). Cloning and distribution of steroid receptor coactivator SRC-1 in quail [Poster presentation]. 31st Annual Meeting o the Society for Neuroscience, San Diego, United States. |
Lakaye, B., de Borman, B., Minet, A., Arckens, L., Vergnes, M., Marescaux, C., & Grisar, T. (March 2000). Increased Expression of mRNA Encoding Ferritin Heavy Chain in Brain Structures of a Rat Model of Absence Epilepsy. Experimental Neurology, 162 (1), 112-20. doi:10.1006/exnr.2000.7303 Peer Reviewed verified by ORBi |
Foidart, A., Lakaye, B., Grisar, T., Ball, G. F., & Balthazart, J. (05 September 1999). Estrogen Receptor-Beta in Quail: Cloning, Tissue Expression and Neuroanatomical Distribution. Journal of Neurobiology, 40 (3), 327-42. doi:10.1002/(SICI)1097-4695(19990905)40:3<327::AID-NEU5>3.0.CO;2-L Peer Reviewed verified by ORBi |
de Borman, B., Lakaye, B., Minet, A., Zorzi, W., Vergnes, M., Marescaux, C., & Grisar, T. (10 February 1999). Expression of Mrna Encoding Alpha1e and Alpha1g Subunit in the Brain of a Rat Model of Absence Epilepsy. Neuroreport, 10 (3), 569-74. doi:10.1097/00001756-199902250-00023 Peer Reviewed verified by ORBi |
Grisar, T., Lakaye, B., Thomas, E., Bettendorff, L., & Minet, A. (1999). The Molecular Neuron-Glia Couple and Epileptogenesis. Advances in Neurology, 79, 591-602. Peer Reviewed verified by ORBi |
Thellin, O., Zorzi, W., Lakaye, B., De Borman, B., Coumans, B., Hennen, G., Grisar, T., Igout, A., & Heinen, E. (1999). Housekeeping Genes as Internal Standards: Use and Limits. Journal of Biotechnology, 75 (2-3), 291-5. doi:10.1016/S0168-1656(99)00163-7 Peer Reviewed verified by ORBi |
Ball, G. F., Bernard, D. J., Foidart, A., Lakaye, B., & Balthazart, J. (1999). Steroid sensitive sites in the avian brain: does the distribution of the estrogen receptor alpha and beta types provide insight into their function? Brain, Behavior and Evolution, 54, 28-40. doi:10.1159/000006609 Peer Reviewed verified by ORBi |
Lakaye, B., Dubus, A., Lepage, S., Groslambert, S., & Frère, J.-M. (January 1999). When Drug Inactivation Renders the Target Irrelevant to Antibiotic Resistance: A Case Story with Beta-Lactams. Molecular Microbiology, 31 (1), 89-101. doi:10.1046/j.1365-2958.1999.01150.x Peer Reviewed verified by ORBi |
Grisar, T., Lakaye, B., Thomas, E., Bettendorff, L., & Minet, A. (1999). The molecular neuron-glia couple and epileptogenesis. In A. V. Delgado-Escueta, W. A. Wilson, R. W. Olsen, ... R. J. Porter (Eds.), Jasper's Basic Mechanisms of the Epilepsies, 3rd edition. Philadelphia, United States - Pennsylvania: Lippincott Williams & Wilkins. |
Lakaye, B., Foidart, A., Grisar, T., & Balthazart, J. (24 August 1998). Partial Cloning and Distribution of Estrogen Receptor Beta in the Avian Brain. Neuroreport, 9 (12), 2743-8. doi:10.1097/00001756-199808240-00011 Peer Reviewed verified by ORBi |
Lakaye, B., Minet, A., Zorzi, W., & Grisar, T. (10 February 1998). Cloning of the Rat Brain Cdna Encoding for the Slc-1 G Protein-Coupled Receptor Reveals the Presence of an Intron in the Gene. Biochimica et Biophysica Acta, 1401 (2), 216-20. doi:10.1016/S0167-4889(97)00135-3 Peer Reviewed verified by ORBi |
Zorzi, W., Thellin, O., Coumans, B., Mélot, F., Hennen, G., Lakaye, B., Igout, A., & Heinen, E. (1998). Demonstration of the expression of CD95 ligand transcript and protein in human placenta. Placenta, 19 (4), 269-277. doi:10.1016/S0143-4004(98)90058-3 Peer Reviewed verified by ORBi |
Adam, M., Fraipont, C., Rhazi, N., Nguyen-Disteche, M., Lakaye, B., Frère, J.-M., Devreese, B., Van Beeumen, J., van Heijenoort, Y., van Heijenoort, J., & Ghuysen, J.-M. (October 1997). The Bimodular G57-V577 Polypeptide Chain of the Class B Penicillin-Binding Protein 3 of Escherichia Coli Catalyzes Peptide Bond Formation from Thiolesters and Does Not Catalyze Glycan Chain Polymerization from the Lipid II Intermediate. Journal of Bacteriology, 179 (19), 6005-6009. doi:10.1128/jb.179.19.6005-6009.1997 Peer Reviewed verified by ORBi |
Grisar, T., Lakaye, B., & Thomas, E. (October 1996). Molecular Basis of Neuronal Biorhythms and Paroxysms. Archives of Physiology and Biochemistry, 104 (6), 770-4. doi:10.1076/apab.104.6.770.12915 Peer Reviewed verified by ORBi |
Lepage, S., Lakaye, B., Galleni, M., Thamm, I., Crine, M., Groslambert, S., & Frère, J.-M. (April 1995). Saturation of Penicillin-Binding Protein 1 by Beta-Lactam Antibiotics in Growing Cells of Bacillus Licheniformis. Molecular Microbiology, 16 (2), 365-72. doi:10.1111/j.1365-2958.1995.tb02308.x Peer Reviewed verified by ORBi |
Lepage, S., Galleni, M., Lakaye, B., Joris, B., Thamm, I., & Frère, J.-M. (1995). Kinetic properties of the Bacillus licheniformis Penicillin-binding proteins. Biochemical Journal, 309, 49-53. doi:10.1042/bj3090049 Peer Reviewed verified by ORBi |
Lakaye, B., Damblon, C., Jamin, M., Galleni, M., Lepage, S., Joris, B., Marchand-Brynaert, J., Frydrychh, C., & Frère, J.-M. (1994). Synthesis, purification and kinetic properties of fluorescein-labelled penicillins. Biochemical Journal, 300, 141-145. doi:10.1042/bj3000141 Peer Reviewed verified by ORBi |
Granier, B., Jamin, M., Adam, M., Galleni, M., Lakaye, B., Zorzi, W., Grandchamps, J., Wilkin, J.-M., Fraipont, C., Joris, B., Duez, C., Nguyen-Distèche, M., Coyette, J., Leyh-Bouille, M., Dusart, J., Christians, L., Frère, J.-M., & Ghuysen, J.-M. (1994). Serine-Type D-Ala-D-Ala Peptidases and Penicillin-Binding Proteins. Methods in Enzymology, 244, 249-266. doi:10.1016/0076-6879(94)44021-2 Peer Reviewed verified by ORBi |
Galleni, M., Lakaye, B., Lepage, S., Jamin, M., Thamm, I., Joris, B., & Frère, J.-M. (01 April 1993). A New, Highly Sensitive Method for the Detection and Quantification of Penicillin-Binding Proteins. Biochemical Journal, 291 ((Pt 1)), 19-21. doi:10.1042/bj2910019 Peer Reviewed verified by ORBi |
Duez, C., Lakaye, B., Houba, S., Dusart, J., & Ghuysen, J.-M. (01 September 1990). Cloning, Nucleotide Sequence and Amplified Expression of the Gene Encoding the Extracellular Metallo (Zn) Dd-Peptidase of Streptomyces Albus G. FEMS Microbiology Letters, 71 (1-2), 215-219. doi:10.1016/0378-1097(90)90059-Y Peer Reviewed verified by ORBi |