coumarins; fraxin; Fraxinus excelsior; RP HPTLC densitometry; RP HPLC
Abstract :
[en] The present work describes a rapid and selective assay for fraxin based on its characteristic fluorescent properties by densitometry on reversed-phase HPTLC plates. Two chromatographgic procedures (Silicagel and RP 18) have been assessed and the results compared to those obtained by reversed-phase HPLC on ODS-silica. The amount of fraxin found in six commercial batches of Fraxinus excelsior leaves ( based on dry weight) ranged from 0.1 to 0.2%.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Poukens-Renwart, P.
Tits, Monique ; Université de Liège - ULiège > Département de pharmacie > Phytochimie et phytothérapie
Wauters, Jean-Noël ; Université de Liège - ULiège > Département de pharmacie > Département de pharmacie
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
English
Title :
Reversed-Phase Hptlc Densitometric Evaluation of Fraxin in Fraxinus Excelsior Leaves
Medicamentsa`base de plantes, Bulletin officiel no. 90122 bis, Ministe`re des Affaires sociales et de la Solidarite´. Direction de la Pharmacie, Paris; 1990.
Directives relativesa`la constitution du dossier d'enregistrement des medicamentsa`base de plantes, Ministe`re de la Sante´Publique et de l'Environnement, Bruxelles, Circulaire no. 367, Liste IV; 1990.
