[en] In bioanalytical applications of surface-enhanced Raman scattering (SERS), the protein corona poses a dual problem. It stabilises suspensions of nanoparticles used as SERS substrates and it prevents the analyte of interest to adsorb onto the surface of the SERS substrates.
In this context, a new home-made and biocompatible device was designed to remove the proteins from the analysed medium. The analysis configuration, with a handheld Raman spectrophotometer, furthermore enabled to conduct real-time monitoring in a non-destructive and non-invasive way.
Research Center/Unit :
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
Disciplines :
Chemistry Pharmacy, pharmacology & toxicology
Author, co-author :
Dumont, Elodie ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
De Bleye, Charlotte ; Université de Liège - ULiège > Département de pharmacie > Département de pharmacie
