Hyphenated liquid chromatography-gas chromatography technique: Recent evolution and applications

Interfaces; LC×GC; LC-GC; Liquid chromatography-gas chromatography; Normal phase LC (NPLC); Reverse phase LC (RPLC); Flexible interfaces; Liquid chromatography-gas chromatographies; Normal phase; Programmed temperature vaporizer; Reverse phase; Technical progress; Water based; Interfaces (materials); Liquid chromatography; Phase interfaces; Gas chromatography; Animals; Chromatography, Gas; Chromatography, Liquid; Humans

Abstract :

[en] Liquid chromatography (LC) hyphenated with gas chromatography (GC) was first presented in 1979. Since then an intensive study has been carried out to explore different types of interfaces both for coupling normal-phase (NP) and reverse-phase (RP) LC with GC. The present review focuses on the technical progress and applications presented in the last decade, and it describes the most used interfaces. In fact, more flexible interfaces have been studied to improve the use of LC-GC, in particular the use of a programmed temperature vaporizer (PTV) injector. An intensive effort has also been devoted to optimizing the coupling of reverse-phase LC for analysis of water-based samples. A brief overview of comprehensive approaches (LC. × GC) is discussed along with perspective for further improvement of the technique. © 2012 Elsevier B.V.

Disciplines :

Chemistry

Author, co-author :

Purcaro, Giorgia ; Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Chimie des agro-biosystèmes

Moret, S.; Dipartimento di Scienze degli Alimenti, Università di Udine, Italy

Conte, L.; Dipartimento di Scienze degli Alimenti, Università di Udine, Italy

Language :

English

Title :

Hyphenated liquid chromatography-gas chromatography technique: Recent evolution and applications

Publication date :

2012

Journal title :

Journal of Chromatography. A

ISSN :

0021-9673

eISSN :

1873-3778

Publisher :

Elsevier, Amsterdam, Netherlands

Volume :

1255

Pages :

100-111

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 11 January 2019

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