Reference : A simple and easy-to-implement SERS approach overcoming the nanoparticle stabilisatio...
Scientific congresses and symposiums : Unpublished conference/Abstract
Physical, chemical, mathematical & earth Sciences : Chemistry
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/227757
A simple and easy-to-implement SERS approach overcoming the nanoparticle stabilisation by serum proteins: application to dopamine and PC-12 cells
English
Dumont, Elodie mailto [Université de Liège - ULiège > Département de pharmacie > Chimie analytique >]
De Bleye, Charlotte mailto [Université de Liège - ULiège > Département de pharmacie > Département de pharmacie >]
Cailletaud, Johan mailto [Université de Liège - ULiège > Département de pharmacie > Chimie analytique >]
Deidda, Riccardo mailto [Université de Liège - ULiège > Département de pharmacie > Chimie analytique >]
Sacre, Pierre-Yves mailto [Université de Liège - ULiège > Département de pharmacie > Chimie analytique >]
Van Lerberghe, Pierre-Bernard mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
Rogister, Bernard mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
Hubert, Philippe mailto [Université de Liège - ULiège > Département de pharmacie > Chimie analytique >]
Ziemons, Eric mailto [Université de Liège - ULiège > Département de pharmacie > Département de pharmacie >]
11-Sep-2018
No
No
International
11th International Symposium on Drug Analysis - 29th International Symposium on Pharmaceutical and Biomedical Analysis (DA-PBA 2018)
Du 09 septembre 2018 au 12 septembre 2018
Leuven
Belgium
[en] Surface-Enhanced Raman Scattering (SERS) ; Gold Nanoparticles ; Dopamine ; Quantitative analyses ; Cellular analysis ; PC-12 cells
[en] This lecture presents the different steps regarding the development of a label-free SERS analytical method that was able to overcome the nanoparticle stabilisation caused by serum proteins. It relied on the pre-aggregation of the SERS substrate, which was a suspension of gold nanoparticles. Furthermore, several applications of the developed methodology were presented: the quantification of dopamine in the culture medium of rat phaeochromocytoma PC-12 cells as well as the influence of calcium, potassium and dexamethasone on dopamine exocytosis from these cells.
Centre Interdisciplinaire de Recherche sur le Médicament - CIRM
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/227757
The presentation has been rewarded by the Young Scientist Prize.

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