Mitochondrial function is altered in horse atypical myopathy

Horse; Acer; Methylenecyclopropyl acetic acid-CoA; Skeletal muscle; Rhabdomyolysis; Acylcarnitines; High-resolution respirometry; Maple; Cheval; Erable; MCPA; Muscle; Myopathie; Myopathie atypique; Atypical myopathy

Abstract :

[en] Equine atypical myopathy in Europe is a fatal rhabdomyolysis syndrome that results from the ingestion of hypoglycin A contained in seeds and seedlings of Acer pseudoplatanus. The hallmark of atypical myopathy consists of a severe alteration in the energy metabolism including a severe impairment in muscle mitochondrial respiration that could contribute to its high death rate

Research Center/Unit :

Fundamental and Applied Research for Animals & Health (FARAH)

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Lemieux, Hélène

BOEMER, François ; Centre Hospitalier Universitaire de Liège - CHU > Service de génétique

Van Galen, Gaby

Serteyn, Didier ; Université de Liège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Anesthésiologie gén. et pathologie chirurg. des grds animaux

Amory, Hélène ; Université de Liège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Médecine interne des équidés

Baise, Etienne ; Université de Liège > Département des productions animales (DPA) > Biostatistique, économie, sélection animale

Cassart, Dominique ; Université de Liège > Département de morphologie et pathologie (DMP) > Département de morphologie et pathologie (DMP)

van Loon, Gunther

Marcillaud-Pitel, Christel

Votion, Dominique ; Université de Liège > Scientifiques attachés au Doyen (F MV)

Language :

English

Title :

Mitochondrial function is altered in horse atypical myopathy

Alternative titles :

[fr] La fonction mitochondriale est défectueuse chez le cheval souffrant de myopathie atypique

Publication date :

2016

Journal title :

Mitochondrion

ISSN :

1567-7249

eISSN :

1872-8278

Publisher :

Elsevier Science

Volume :

Pages :

35-41

Peer reviewed :

Peer Reviewed verified by ORBi

Funders :

IFCE - Institut Français du Cheval et de l'Équitation
DGA - Région wallonne. Direction générale de l'Agriculture
ULg FSR - Université de Liège. Fonds spéciaux pour la recherche

Available on ORBi :

since 05 July 2016

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Bibliography

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