Reference : Efficacy of the RemoweLL cardiotomy reservoir for fat and leucocyte removal from shed...
Scientific journals : Article
Human health sciences : Surgery
http://hdl.handle.net/2268/197243
Efficacy of the RemoweLL cardiotomy reservoir for fat and leucocyte removal from shed mediastinal blood: a randomized controlled trial.
English
LAGNY, Marc-Gilbert mailto [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire (+1BC) >]
GOTHOT, André mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service d'hématologie biologique et immuno-hématologie >]
HANS, Grégory mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation >]
KOCH, Jean-Noël mailto [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire (+1BC) >]
BLAFFART, Francine mailto [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire (+1BC) >]
HELLA, Dominique mailto [Centre Hospitalier Universitaire de Liège - CHU > > Bloc opératoire chirurgie cardio-vasculaire (+1BC) >]
Donneau, Anne-Françoise mailto [Université de Liège > Département des sciences de la santé publique > Biostatistique >]
ROEDIGER, Laurence mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation >]
LECUT, Christelle mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service d'hématologie biologique et immuno-hématologie >]
PINCEMAIL, Joël mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique >]
CHERAMY-BIEN, Jean-Paul mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique >]
DEFRAIGNE, Jean mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique >]
16-May-2016
Perfusion
SAGE Publications
Yes (verified by ORBi)
International
0267-6591
1477-111X
London
United Kingdom
[en] leucocyte removal ; lipids ; filtration ; cardiotomy reservoir ; cardiopulmonary bypass
[en] Efficacy of the RemoweLL cardiotomy reservoir for Fat and Leucocyte removal from shed mediastinal blood: a randomized controlled trial.
ABSTRACT (176 words)
Introduction
Re-transfusion of lipid particles and activated leucocytes with shed mediastinal blood (SMB) can aggravate cardiopulmonary bypass-associated inflammation and increase the embolic load. This study evaluated the fat and leucocyte removal capacity of the RemoweLL cardiotomy reservoir.
Methods
Forty-five patients undergoing elective on-pump cardiac surgery were randomly allocated to filtration of SMB using the RemoweLL or the Admiral cardiotomy reservoir. The primary outcome was the drop in leucocytes and lipid particles obtained with the two filters. The effect of the filters on other blood cells and inflammatory mediators such as myeloperoxidase (MPO) was also assessed.


Results
The RemoweLL cardiotomy filter removed 16.5 % of the leucocytes (P < 0.001) while no significant removal of leucocytes was observed with the Admiral (P = 0.48). The percentage reductions in lipid particles were similar in the two groups (26% vs 23 %, P = 0.2). Both filters similarly affected the level of MPO (P = 0.71).
Discussion
The RemoweLL filter more effectively removed leucocytes from SMB than the Admiral. It offered no advantage in term of lipid particle clearance.
Professionals
http://hdl.handle.net/2268/197243
10.1177/0267659116649427

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