Article (Scientific journals)
Hox protein interactions: screening and network building.
Bergiers, Isabelle; Lambert, Barbara; Daakour, Sarah et al.
2014In Methods in Molecular Biology, 1196, p. 319-48
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Keywords :
Computational Biology/methods; Databases, Protein; High-Throughput Screening Assays; Homeodomain Proteins/metabolism; Protein Binding; Protein Interaction Mapping/methods; Protein Interaction Maps; Reproducibility of Results; Two-Hybrid System Techniques; Yeasts/metabolism
Abstract :
[en] Understanding the mode of action of Hox proteins requires the identification of molecular and cellular pathways they take part in. This includes to characterize the networks of protein-protein interactions involving Hox proteins. In this chapter we propose a strategy and methods to map Hox interaction networks, from yeast two-hybrid and high-throughput yeast two-hybrid interaction screening to bioinformatic analyses based on the software platform Cytoscape.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Bergiers, Isabelle
Lambert, Barbara
Daakour, Sarah ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Biologie cell. et moléc.
Twizere, Jean-Claude  ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Biologie cell. et moléc.
Rezsohazy, Rene
Language :
English
Title :
Hox protein interactions: screening and network building.
Publication date :
2014
Journal title :
Methods in Molecular Biology
ISSN :
1064-3745
eISSN :
1940-6029
Publisher :
Humana Press, Clifton, United States - New Jersey
Volume :
1196
Pages :
319-48
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 22 February 2016

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