Ghuysen JM. 1988. Bacterial active-site serine penicillin-interactive proteins and domains: mechanism, structure, and evolution. Rev. Infect. Dis. 10:726-732.
Waxman DJ, Strominger JL. 1983. Penicillin-binding proteins and the mechanism of action of beta-lactam antibiotics. Annu. Rev. Biochem. 52:825-869.
Sauvage E, Kerff F, Terrak M, Ayala JA, Charlier P. 2008. The penicillinbinding proteins: structure and role in peptidoglycan biosynthesis. FEMS Microbiol. Rev. 32:234-258.
Rice LB, Carias LL, Hutton-Thomas R, Sifaoui F, Gutmann L, Rudin SD. 2001. Penicillin-binding protein 5 and expression of ampicillin resistance in Enterococcus faecium. Antimicrob. Agents Chemother. 45:1480-1486.
Zorzi W, Zhou XY, Dardenne O, Lamotte J, Raze D, Pierre J, Gutmann L, Coyette J. 1996. Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium. J. Bacteriol. 178:4948-4957.
Ge Y, Biek D, Talbot GH, Sahm DF. 2008. In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. Antimicrob. Agents Chemother. 52:3398-3407.
Sader HS, Fritsche TR, Jones RN. 2008. Antimicrobial activities of ceftaroline and ME1036 tested against clinical strains of communityacquired methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 52:1153-1155.
Sader HS, Fritsche TR, Kaniga K, Ge Y, Jones RN. 2005. Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains. Antimicrob. Agents Chemother. 49:3501-3512.
Goffin C, Ghuysen JM. 1998. Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs. Microbiol. Mol. Biol. Rev. 62:1079-1093.
Moisan H, Pruneau M, Malouin F. 2010. Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae. J. Antimicrob. Chemother. 65:713-716.
Villegas-Estrada A, Lee M, Hesek D, Vakulenko SB, Mobashery S. 2008. Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics. J. Am. Chem. Soc. 130:9212-9213.
Mushtaq S, Warner M, Ge Y, Kaniga K, Livermore DM. 2007. In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes. J. Antimicrob. Chemother. 60: 300-311.
Clinical and Laboratory Standards Institute. 2006. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 7th ed. Clinical and Laboratory Standards Institute, Wayne, PA.
Small PM, Chambers HF. 1990. Vancomycin for Staphylococcus aureus endocarditis in intravenous drug users. Antimicrob. Agents Chemother. 34:1227-1231.
Zhao G, Meier TI, Kahl SD, Gee KR, Blaszczak LC. 1999. Bocillin FL, a sensitive and commercially available reagent for detection of penicillinbinding proteins. Antimicrob. Agents Chemother. 43:1124-1128.
el Kharroubi A, Piras G, Jacques P, Szabo I, Van Beeumen J, Coyette J, Ghuysen JM. 1989. Active-site and membrane topology of the DDpeptidase/ penicillin-binding protein no. 6 of Enterococcus hirae (Streptococcus faecium) A.T.C.C. 9790. Biochem. J. 262:457-462.
Henry X, Amoroso A, Coyette J, Joris B. 2010. Interaction of ceftobiprole with the low-affinity PBP 5 of Enterococcus faecium. Antimicrob. Agents Chemother. 54:953-955.
Sauvage E, Kerff F, Fonze E, Herman R, Schoot B, Marquette JP, Taburet Y, Prevost D, Dumas J, Leonard G, Stefanic P, Coyette J, Charlier P. 2002. The 2.4-A crystal structure of the penicillin-resistant penicillin-binding protein PBP5fm from Enterococcus faecium in complex with benzylpenicillin. Cell. Mol. Life Sci. 59:1223-1232.
Lemaire S, Glupczynski Y, Duval V, Joris B, Tulkens PM, Van Bambeke F. 2009. Activities of ceftobiprole and other cephalosporins against extracellular and intracellular (THP-1 macrophages and keratinocytes) forms of methicillin-sensitive (MSSA) and methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 53:2289-2297.
Zervosen A, Zapun A, Frere JM. 2013. Inhibition of Streptococcus pneumoniae penicillin-binding protein 2x and Actinomadura R39 DDpeptidase activities by ceftaroline. Antimicrob. Agents Chemother. 57: 661-663.