Reference : Vieillissement et cancer: coincidence ou relation etiologique?
Scientific journals : Article
Human health sciences : Immunology & infectious disease
http://hdl.handle.net/2268/185912
Vieillissement et cancer: coincidence ou relation etiologique?
French
[en] Aging and cancer: coincidence or etiologic relationship?
Duray, A. [> >]
Demoulin, Stéphanie mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques >]
Petermans, Jean mailto [Université de Liège - ULiège > Département des sciences cliniques > Gériatrie >]
Moutschen, Michel mailto [Université de Liège - ULiège > Département des sciences cliniques > GIGA-R:Immunopath. - Maladies infect. et médec. inter. gén. >]
Saussez, S. [> >]
Jerusalem, Guy mailto [Université de Liège - ULiège > Département des sciences cliniques > Oncologie >]
Delvenne, Philippe mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques >]
2014
Revue Médicale de Liège
69
5-6
276-81
Yes (verified by ORBi)
National
0370-629X
2566-1566
Belgium
[en] Age of Onset ; Aged ; Aged, 80 and over ; Aging/physiology ; Cell Aging/genetics/immunology ; Humans ; Neoplasms/epidemiology/etiology ; Oxidative Stress/physiology ; Telomere Homeostasis
[en] In Belgium and in other countries, the Cancer Registry data show an increased incidence of cancers related to age, the majority of tumors being diagnosed beyond 60 years. However, the mechanisms responsible for this increase are not clear. Cancer could be chronologically associated with aging because of the long latency period between the exposition to carcinogenic agents and the appearance of clinical signs. Aging could also predispose directly to cancer by different mechanisms (impaired immune response, increased oxidative stress, shortening of telomeres, accumulation of senescent cells). In this review, we propose to describe different hypotheses which could explain the increased incidence of cancers in the elderly.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/185912

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