[en] The γ- and δ-lactones of less than 12 carbons constitute a group of compounds of great interest to the flavour industry. It is possible to produce some of these lactones through biotechnology. For instance, γ-decalactone can be obtained by biotransformation of methyl ricinoleate. Among the organisms used for this bioproduction, Yarrowia lipolytica is a yeast of choice. It is well adapted to growth on hydrophobic substrates, thanks to its efficient and numerous lipases, cytochrome P450, acylCoA oxidases and its ability to produce biosurfactants. Furthermore, genetic tools have been developed for its study. This review deals with the production of lactones by Y. lipolytica with special emphasis on the biotransformarion of methyl ricinoleate to γ-decalactone. When appropriate, information from the lipid metabolism of other yeast species is presented.
Disciplines :
Biotechnology
Author, co-author :
Waché, Y.; Laboratoire de Microbiologie, UMR UB/INRA 1082, ENSBANA, 1 Esplanade Erasme, 21000 Dijon, France
Aguedo, Mario ; Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle
Nicaud, J.-M.; Lab. de Genet. des Micro-Organismes, INRA-CNRS, URA 1925, Thiverval-Grignon, France
Belin, J.-M.; Laboratoire de Microbiologie, UMR UB/INRA 1082, ENSBANA, 1 Esplanade Erasme, 21000 Dijon, France
Language :
English
Title :
Catabolism of hydroxyacids and biotechnological production of lactones by Yarrowia lipolytica
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