[en] Antibodies have become essential tools in recent decades, with a wide range of applications in the laboratory and in human and veterinary medicine. The use of laying hens, instead of mammals, to obtain the necessary antibodies from the eggs is a major advance in terms of animal welfare because it makes blood sampling obsolete. However, the advantages of this technology are numerous, in addition to the animal welfare aspect. With a carefully designed immunization protocol, it is possible to enhance both the hen’s immune response and its welfare during the process. This review puts forward recommendations how to do this and discusses recent approaches on improving the technology. [fr] Les anticorps sont devenus au fil des années des outils essentiels avec des applications variées tant au laboratoire qu’en médecine humaine ou vétérinaire. L’utilisation de poules pondeuses plutôt que de mammifères pour leur obtention représente déjà en soi une avancée majeure en termes de bien-être animal puisque cette option permettant une collecte des anticorps dans les œufs rend tout simplement obsolète la saignée de l’animal producteur. Les avantages de cette technologie sont cependant multiples et vont bien au-delà de l’aspect de protection de l’animal. En optimisant le protocole d’immunisation, il est possible d’améliorer à la fois la réponse immunitaire de la poule et son bien-être en période de production. Cette synthèse bibliographique propose des recommandations à cette fin. Les approches les plus récentes pour améliorer la technologie sont également discutées.
Disciplines :
Animal production & animal husbandry Biotechnology Veterinary medicine & animal health
Author, co-author :
Marcq, Christopher ; Université de Liège - ULiège > Sciences agronomiques > Zootechnie
Thewis, André ; Université de Liège - ULiège > Sciences agronomiques > Zootechnie
Portetelle, Daniel ; Université de Liège - ULiège > Chimie et bio-industries > Microbiologie et génomique
Refinement of the production of antigen-specific hen egg yolk antibodies (IgY) intended for passive dietary immunization in animals: A review
Alternative titles :
[fr] Amélioration dans l’obtention d’anticorps du jaune d’œuf (IgY) spécifiques d’un antigène et destinés à l’immunisation passive par voie alimentaire chez l’animal : Synthèse bibliographique
Publication date :
2013
Journal title :
Biotechnologie, Agronomie, Société et Environnement
ISSN :
1370-6233
eISSN :
1780-4507
Publisher :
Presses Agronomiques de Gembloux, Gembloux, Belgium
Volume :
17
Issue :
3
Pages :
483-493
Peer reviewed :
Peer Reviewed verified by ORBi
Name of the research project :
D31-1238 : Développement et utilisation des anticorps du jaune d'oeuf en vue du contrôle des Salmonella spp. dans le tube digestif du poulet de chair
Funders :
SPW DG03-DGARNE - Service Public de Wallonie. Direction Générale Opérationnelle Agriculture, Ressources naturelles et Environnement
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