Reference : Genetic variation in PLAG1 associates with early life body weight and peripubertal we...
Scientific journals : Article
Life sciences : Genetics & genetic processes
http://hdl.handle.net/2268/138614
Genetic variation in PLAG1 associates with early life body weight and peripubertal weight and growth in Bos taurus.
English
Littlejohn, M. [> >]
Grala, T. [> >]
Sanders, K. [> >]
Walker, C. [> >]
Waghorn, G. [> >]
Macdonald, K. [> >]
Coppieters, Wouter mailto [Université de Liège - ULiège > Département de productions animales > GIGA-R : Génomique animale >]
Georges, Michel mailto [Université de Liège - ULiège > Département de productions animales > GIGA-R : Génomique animale >]
Spelman, Richard [> >]
Hillerton, E. [> >]
Davis, S. [> >]
Snell, R. [> >]
Oct-2012
Animal Genetics
43
5
591-4
Yes (verified by ORBi)
International
0268-9146
1365-2052
England
[en] Variation at the pleiomorphic adenoma gene 1 (PLAG1) locus has recently been implicated in the regulation of stature and weight in Bos taurus. Using a population of 942 outbred Holstein-Friesian dairy calves, we report confirmation of this effect, demonstrating strong association of early life body weight with PLAG1 genotype. Peripubertal body weight and growth rate were also significantly associated with PLAG1 genotype. Growth rate per kilogram of body weight, daily feed intake, gross feed efficiency and residual feed intake were not significantly associated with PLAG1 genotype. This study supports the status of PLAG1 as a key regulator of mammalian growth. Further, the data indicate the utility of PLAG1 polymorphisms for the selection of animals to achieve enhanced weight gain or conversely to aid the selection of animals with lower mature body weight and thus lower maintenance energy requirements.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/138614
10.1111/j.1365-2052.2011.02293.x
(c) 2011 The Authors, Animal Genetics (c) 2011 Stichting International Foundation for Animal Genetics.

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
age2293.pdfPublisher postprint102.27 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.