Profil

Georges Michel

Dpt. de gestion vétérinaire des Ressources Animales (DRA) > Génomique animale

GIGA Medical Genomics - Unit of Animal Genomics

See author's contact details
ORCID
0000-0003-4124-2375
Main Referenced Co-authors
Coppieters, Wouter  (113)
Charlier, Carole  (110)
Karim, Latifa  (55)
Druet, Tom  (50)
Durkin, Keith  (33)
Main Referenced Keywords
Animals (54); Humans (30); Female (24); Male (24); Cattle (23);
Main Referenced Unit & Research Centers
Giga-Genetics - ULiège [BE] (19)
GIGA - Unit of Animal Genomics (2)
GIGA‐R - Giga‐Research - ULiège [BE] (2)
Systmod (2)
Breakthrough Breast Cancer Research Centre (1)
Main Referenced Disciplines
Genetics & genetic processes (206)
Veterinary medicine & animal health (109)
Animal production & animal husbandry (36)
Biochemistry, biophysics & molecular biology (15)
Agriculture & agronomy (14)

Publications (total 343)

The most downloaded
2169 downloads
Liu, J., Van Sommeren, S., Huang, H., Ng, S. C., International IBD Genetics Consortium, Weersma, R., & Georges, M. (Other coll.). (September 2015). Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nature Genetics, 47 (9), 979-986. doi:10.1038/ng.3359 https://hdl.handle.net/2268/232262

The most cited

3562 citations (Scopus®)

Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Schumm, L. P., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., ... Cho, J. H. (October 2012). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature, 491 (7422), 119-24. doi:10.1038/nature11582 https://hdl.handle.net/2268/138500

Tang, L., Swedlund, B., Dupont, S., Harland, C., Costa Monteiro Moreira, G., Durkin, K., Artesi, M., Mullaart, E., Sartelet, A., Karim, L., Coppieters, W., Georges, M., & Charlier, C. (09 March 2024). GWAS reveals determinants of mobilization rate and dynamics of an active endogenous retrovirus of cattle. Nature Communications, 15 (1), 2154. doi:10.1038/s41467-024-46434-1
Peer Reviewed verified by ORBi

Gualdrón Duarte, J. L., Yuan, C., Gori, A.-S., Moreira, G. C. M., Takeda, H., Coppieters, W., Charlier, C., Georges, M., & Druet, T. (28 November 2023). Sequenced-based GWAS for linear classification traits in Belgian Blue beef cattle reveals new coding variants in genes regulating body size in mammals. Genetics, Selection, Evolution, 55 (1), 83. doi:10.1186/s12711-023-00857-4
Peer Reviewed verified by ORBi

Lee, Y. L., Bouwman, A. C., Harland, C., Bosse, M., Costa Monteiro Moreira, G., Veerkamp, R. F., Mullaart, E., CAMBISANO, N., Groenen, M. A. M., Karim, L., Coppieters, W., Georges, M., & Charlier, C. (2023). The rate of de novo structural variation is increased in in vitro-produced offspring and preferentially affects the paternal genome. Genome Research. doi:10.1101/gr.277884.123
Peer Reviewed verified by ORBi

Yuan, C., Tang, L., Lopdell, T., Petrov, V. A., Oget-Ebrad, C., Moreira, G. C. M., Gualdrón Duarte, J. L., Sartelet, A., Cheng, Z., Salavati, M., Wathes, D. C., Crowe, M. A., GplusE Consortium, Coppieters, W., Littlejohn, M., Charlier, C., Druet, T., Georges, M.* , & Takeda, H.*. (October 2023). An organism-wide ATAC-seq peak catalog for the bovine and its use to identify regulatory variants. Genome Research, 33 (10), 1848 - 1864. doi:10.1101/gr.277947.123
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Baumdick, M. E., Niehrs, A., Degenhardt, F., Schwerk, M., Hinrichs, O., Jordan-Paiz, A., Padoan, B., Wegner, L. H. M., Schloer, S., Zecher, B. F., Malsy, J., Joshi, V. R., Illig, C., Schröder-Schwarz, J., Möller, K. J., Hamburg Intestinal Tissue Study, G., Martin, M. P., Yuki, Y., Ozawa, M., ... Zhao, Z. Z. (Other coll.). (October 2023). HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44(+) Natural Killer Cells in Ulcerative Colitis. Gastroenterology, 165 (4), 946-962.e13. doi:10.1053/j.gastro.2023.06.034
Peer Reviewed verified by ORBi

COVID-19 Host Genetics Initiative, Rahmouni, S., Georges, M., Moutschen, M., Darcis, G., & Beguin, Y. (September 2023). A second update on mapping the human genetic architecture of COVID-19. Nature, 621 (7977), 7 - E26. doi:10.1038/s41586-023-06355-3
Peer Reviewed verified by ORBi

Lee, Y. L., Bosse, M., Takeda, H., Moreira, G. C. M., Karim, L., Druet, T., Oget-Ebrad, C., Coppieters, W., Veerkamp, R. F., Groenen, M. A. M., Georges, M., Bouwman, A. C., & Charlier, C. (01 May 2023). High-resolution structural variants catalogue in a large-scale whole genome sequenced bovine family cohort data. BMC Genomics, 24 (1), 225. doi:10.1186/s12864-023-09259-8
Peer Reviewed verified by ORBi

Akhlaghpour, M., Haritunians, T., More, S. K., Thomas, L. S., Stamps, D. T., Dube, S., Li, D., Yang, S., Landers, C. J., Mengesha, E., Hamade, H., Murali, R., Potdar, A. A., Wolf, A. J., Botwin, G. J., Khrom, M., International IBD Genetics Consortium, Ananthakrishnan, A. N., Faubion, W. A., ... Georges, M. (Other coll.). (2023). Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut, 2023-329689. doi:10.1136/gutjnl-2023-329689
Peer Reviewed verified by ORBi

Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique.

Georges, A., Lavergne, A., Mandai, M., Lepiemme, F., Karim, L., Demeulenaere, L., Aguilar Ortmans, D., Schyns, M., Nguyen, L., Rakic, J.-M., Takahashi, M., Georges, M., & Takeda, H. (21 January 2023). Comparing the transcriptome of developing native and iPSC-derived mouse retinae by single cell RNA sequencing. Scientific Reports, 13 (1), 1223. doi:10.1038/s41598-023-28429-y
Peer Reviewed verified by ORBi

Bonaguro, L., Schulte-Schrepping, J., Carraro, C., Sun, L. L., Reiz, B., Gemünd, I., Saglam, A., Rahmouni, S., Georges, M., Arts, P., Hoischen, A., Joosten, L. A. B., van de Veerdonk, F. L., Netea, M. G., Händler, K., Mukherjee, S., Ulas, T., Schultze, J. L., & Aschenbrenner, A. C. (18 November 2022). Human variation in population-wide gene expression data predicts gene perturbation phenotype. iScience, 25 (11), 105328. doi:10.1016/j.isci.2022.105328
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Koshmanova, E., Muto, V., Chylinski, D., MOURAUX, C., Reyt, M., Grignard, M., Talwar, P., Lambot, E., Berthomier, C., Brandewinder, M., Mortazavi, N., Degueldre, C., Luxen, A., Salmon, E., Georges, M., Collette, F., Maquet, P., Van Someren, E., & Vandewalle, G. (10 November 2022). Genetic risk for insomnia is associated with objective sleep measures in young and healthy good sleepers. Neurobiology of Disease, 175, 105924. doi:10.1016/j.nbd.2022.105924
Peer Reviewed verified by ORBi

Mishra, N., Aden, K., Blase, J. I., Baran, N., Bordoni, D., Tran, F., Conrad, C., Avalos, D., Jaeckel, C., Scherer, M., Sørensen, S. B., Overgaard, S. H., Schulte, B., Nikolaus, S., Rey, G., Gasparoni, G., Lyons, P. A., Schultze, J. L., Walter, J., ... Georges, M. (Other coll.). (24 September 2022). Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease. Genome Medicine, 14 (1), 110. doi:10.1186/s13073-022-01112-z
Peer Reviewed verified by ORBi

International IBD Genetics Consortium, Rahmouni, S., Georges, M., & LOUIS, E. (September 2022). Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nature Genetics, 54 (9), 1275-1283. doi:10.1101/2021.06.15.21258641
Peer Reviewed verified by ORBi

Perée, H., Petrov, V., Tokunaga, Y., Jacques, S., Coppieters, W., Louis, E., Georges, M., & Rahmouni, S. (29 August 2022). Towards identifying novel eQTLs driving inherited predisposition to IBD in 22 distinct circulating immune cell populations [Poster presentation]. Internation SYSCID symposium, Kiel, Germany.

Sazonovs, A., Stevens, C. R., Venkataraman, G. R., Yuan, K., Avila, B., Abreu, M. T., Ahmad, T., Allez, M., Ananthakrishnan, A. N., Atzmon, G., Baras, A., Barrett, J. C., Barzilai, N., Beaugerie, L., Beecham, A., Bernstein, C. N., Bitton, A., Bokemeyer, B., Chan, A., ... Daly, M. J. (2022). Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility. Nature Genetics. doi:10.1038/s41588-022-01156-2
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Pathak, G. A., Karjalainen, J., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Andrews, S. J., Kanai, M., Cordioli, M., Polimanti, R., Harerimana, N., Pirinen, M., Liao, R. G., Chwialkowska, K., Trankiem, A., Balaconis, M. K., Nguyen, H., Solomonson, M., Veerapen, K., ... Baillie, J. K. (03 August 2022). A first update on mapping the human genetic architecture of COVID-19. Nature, 608, 1-E10. doi:10.1038/s41586-022-04826-7
Peer Reviewed verified by ORBi

Oget, C., Costa Monteiro Moreira, G., Karim, L., Coppieters, W., Charlier, C., Georges, M., & Druet, T. (08 July 2022). Fine-Scale Study of Meiotic Recombination in Cattle [Paper presentation]. World Congress on Genetics Applied to Livestock Production, Rotterdam, Netherlands.
Peer reviewed

Rombouts, T., Druet, T., Gualdron Duarte, J. L., Ahariz, N., Karim, L., Coppieters, W., De Smet, S., Georges, M., & Charlier, C. (08 July 2022). A hypomorphic mutation in the ATP2A1 gene increases muscle mass yet compromises meat quality of Belgian Blue cattle [Paper presentation]. World Congress on Genetics Applied to Livestock Production, Rotterdam, Netherlands.
Peer reviewed

Lee, Y. L., Bosse, M., Coppieters, W., Veerkamp, R., Karim, L., Oget, C., Druet, T., Groenen, M., Georges, M., Bouwman, A., & Charlier, C. (08 July 2022). Rare CNVs in the bovine genome are not captured well by 50K density genotyping array SNPs [Paper presentation]. World Congress on Genetics Applied to Livestock Production, Rotterdam, Netherlands.
Peer reviewed

Gualdron Duarte, J. L., Gori, A.-S., Costa Monteiro Moreira, G., Georges, M., Charlier, C., & Druet, T. (08 July 2022). Sequence-based multi-trait genome-wide association study for linear classification traits in Belgian Blue beef cattle [Paper presentation]. World Congress on Genetics Applied to Livestock Production, Rotterdam, Netherlands.
Peer reviewed

Yuan, C., Tang, L., Lopdell, T., Oget, C., Costa Monteiro Moreira, G., Gualdron Duarte, J. L., Cheng, Z., Salavati, M., Wathes, D. C., Crowe, M. A., GplusE consortium, Coppieters, W., Charlier, C., Druet, T., Georges, M., & Takeda, H. (08 July 2022). Enrichment of causative variants in tissue-specific and shared ATAC-Seq peaks in cattle [Paper presentation]. World Congress on Genetics Applied to Livestock Production, Rotterdam, Netherlands.
Peer reviewed

Perée, H., Petrov, V., Tokunaga, Y., Jacques, S., Coppieters, W., LOUIS, E., Georges, M., & Rahmouni, S. (May 2022). Towards identifying novel eQTLs driving inherited predisposition to IBD in 22 distinct circulating immune cell populations [Poster presentation]. 34th meeting on The Biology of Genomes.

Petrov, V., Sharapov, S., Shagam, L., Nostaeva, A., Pezer, M., Li, D., Hanić, M., McGovern, D., LOUIS, E., Rahmouni, S., Lauc, G., Georges, M., & Aulchenko, Y. S. (29 April 2022). Association between human gut microbiome and N-glycan composition of total plasma proteome. Frontiers in Microbiology, 13:811922.
Peer Reviewed verified by ORBi

Yang, H.* , Wu, J.* , Huang, X., Zhou, Y., Zhang, Y., Liu, M., Liu, Q., Ke, S., He, M., Fu, H., Fang, S., Xiong, X., Jiang, H., Chen, Z., Wu, Z., Gong, H., Tong, X., Huang, Y., Ma, J., ... Huang, L.*. (2022). ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs. Nature. doi:10.1038/s41586-022-04769-z
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Tokunaga, Y., Wéry, M., Mayer, A., Karim, L., Azarzar, S., Demeulenaere, L., Petrov, V., Deckers, M., Detry, E., Coppieters, W., LOUIS, E., Georges, M., & Rahmouni, S. (09 April 2022). Single cell RNA sequencing to uncover intestinal cell-type specific cis-eQTL driving inherited predisposition to IBD [Paper presentation]. Keystone symposia Single Cell Biology, Florence, Italy.

Zhu, Y., Zhou, Z., Huang, T., Zhang, Z., Li, W., Ling, Z., Jiang, T., Yang, J., Yang, S., Xiao, Y., Charlier, C., Georges, M., Yang, B., & Huang, L. (2022). Mapping and analysis of a spatiotemporal H3K27ac and gene expression spectrum in pigs. Science China Life Sciences. doi:10.1007/s11427-021-2034-5
Peer Reviewed verified by ORBi

Kadri, N. K., Zhang, J., Oget-Ebrad, C., Wang, Y., Couldrey, C., Spelman, R., Charlier, C., Georges, M., & Druet, T. (2022). High male specific contribution of the X-chromosome to individual global recombination rate in dairy cattle. BMC Genomics, 23 (1), 114. doi:10.1186/s12864-022-08328-8
Peer Reviewed verified by ORBi

Oget, C., Kadri, N. K., Moreira, G. C. M., Karim, L., Coppieters, W., Georges, M., & Druet, T. (2022). Benchmarking phasing software with a whole-genome sequenced cattle pedigree. BMC Genomics, 23 (1), 130. doi:10.1186/s12864-022-08354-6
Peer Reviewed verified by ORBi

Nakanishi, T., Pigazzini, S., Degenhardt, F., Cordioli, M., Butler-Laporte, G., Maya-Miles, D., Nafría-Jiménez, B., Bouysran, Y., Niemi, M., Palom, A., Ellinghaus, D., Khan, A., Martínez-Bueno, M., Rolker, S., Amitano, S., Tato, L. R., Fava, F., Spinner, C. D., Prati, D., ... consortium, C.-H. (October 2021). Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. Journal of Clinical Investigation, Online ahead of print.. doi:10.1172/JCI152386
Peer Reviewed verified by ORBi

Oget, C., Kadri, N. K., Costa Monteiro Moreira, G., Karim, L., Coppieters, W., Georges, M., & Druet, T. (02 September 2021). Benchmarking phasing software with whole-genome sequenced cattle trios [Paper presentation]. 72nd Annual Meeting of the European Federation of Animal Science (EAAP), Davos, Switzerland.

Muto, V.* , Koshmanova, E.* , Ghaemmaghami Tabrizi, P.* , Jaspar, M., Meyer, C., Elansary, M., Van Egroo, M., Chylinski, D., Berthomier, C., Brandewinder, M., Mouraux, C., Schmidt, C., Hammad, G., Coppieters, W., Ahariz, N., Degueldre, C., Luxen, A., Salmon, E., Phillips, C., ... Vandewalle, G. (16 July 2021). Alzheimer’s disease genetic risk and sleep phenotypes: association with more slow-waves and daytime sleepiness. Sleep, 44 (1), 137. doi:10.1093/sleep/zsaa137
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Durkin, K., Artesi, M., VAN DEN BROEKE, A., Bours, V., Hahaut, V., & Georges, M. (21 June 2021). Pooled crispr inverse pcr sequencing (pcip-seq): simultaneous sequencing of viral insertion points and the integrated viral genomes with long reads.

Tang, L., Harland, C., Durkin, K., Artesi, M., Costa Monteiro Moreira, G., Karim, L., Deckers, M., Mullaart, E., Coppieters, W., Georges, M., & Charlier, C. (11 May 2021). Evidence for inter-individual variation of ERV de novo transposition rate in the male cattle germline [Paper presentation]. The Biology of Genomes, United States.

Perée, H., Mayer, A., Takeda, H., Karim, L., Deckers, M., Jacques, S., Mni, M., Wéry, M., Azarzar, S., Tokunaga, Y., Coppieters, W., Georges, M., & Rahmouni, S. (May 2021). Comparative analysis of ultra low input RNA sequencing methods for the study of rare immune cell populations [Poster presentation]. 33rd meeting on The Biology of Genomes.

Rapino, F.* , ZHOU, Z.* , RONCERO SANCHEZ, A. M.* , Joiret, M., Seca, C., El Hachem, N., Valenti, G., Latini, S., Shostak, K., Geris, L., Li, P., Huang, G., Mazzucchelli, G., Baiwir, D., Desmet, C., Chariot, A., Georges, M., & Close, P. (2021). Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate. Nature Communications, 12 (1), 2170. doi:10.1038/s41467-021-22254-5
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Artesi, M.* , Hahaut, V.* , Cole, B.* , Lambrechts, L., Ashrafi, F., Marçais, A., Hermine, O., Griebel, P., Arsic, N., van der Meer, F., Burny, A., Bron, D., BIANCHI, E., DELVENNE, P., BOURS, V., Charlier, C., Georges, M., Vandekerckhove, L.* , Van den Broeke, A.* , & Durkin, K.*. (2021). PCIP-seq: simultaneous sequencing of integrated viral genomes and their integration sites with long reads. Genome Biology, 22, 97. doi:10.1186/s13059-021-02307-0
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Marçais, A., Lhermite, L., Artesi, M., Laurent, C., Durkin, K., Hahaut, V., Rosewick, N., Suarez, F., Sibon, D., Cheminant, M., Avettand-Fenoël, V., Bruneau, J., Georges, M., Pique, C., Van den Broeke, A.* , Asnafi, V.* , & Hermine, O.*. (2021). Targeted deep sequencing reveals clonal and subclonal mutational signatures in Adult T-cell leukemia/lymphoma and defines an unfavorable indolent subtype. Leukemia, 35, 764-776. doi:10.1038/s41375-020-0900-3
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Young-Lim, L., Costa Monteiro Moreira, G., Karim, L., Mullart, E., Coppieters, W., Veerkamp, R., Groenen, M., Bosse, M., Bouwman, A., Georges, M., & Charlier, C. (2021). Pedigree-based de novo rate estimation for structural variation in the cattle germline [Poster presentation]. The Biology of Genomes.

Võsa, U., Claringbould, A., Westra, H.-J., Bonder, M. J., Deelen, P., Zeng, B., Kirsten, H., Saha, A., Kreuzhuber, R., Yazar, S., Brugge, H., Battle, A., Visscher, P. M., Yang, J., Scholz, M., Powell, J., Gibson, G., Esko, T., Franke, L., ... Stegle, O. (2021). Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nature Genetics, 53 (9), 1300-1310. doi:10.1038/s41588-021-00913-z
Peer Reviewed verified by ORBi

Lee, Y.-L., Takeda, H., Costa Monteiro Moreira, G., Karim, L., Mullaart, E., Coppieters, W., Appeltant, R., Veerkamp, R. F., Groenen, M. A. M., Georges, M., Bosse, M., Druet, T., Bouwman, A. C., & Charlier, C. (2021). A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle. PLoS Genetics, 17 (7), 1009331. doi:10.1371/journal.pgen.1009331
Peer Reviewed verified by ORBi

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x
Peer Reviewed verified by ORBi

Scherer, M., Gasparoni, G., Rahmouni, S., Shashkova, T., Arnoux, M., Louis, E., Nostaeva, A., Avalos, D., Dermitzakis, E. T., Aulchenko, Y. S., Lengauer, T., Lyons, P. A., Georges, M., & Walter, J. R. (2021). Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR. Epigenetics and Chromatin, 14 (1), 44. doi:10.1186/s13072-021-00415-6
Peer Reviewed verified by ORBi

Lieferinckx, C., De Grève, Z., Toubeau, J. F., Perée, H., Quertinmont, E., Tafciu, V., Minsart, C., Rahmouni, S., Georges, M., Vallée, F., & Franchimont, D. (2021). New approach to determine the healthy immune variations by combining clustering methods. Scientific Reports, 11, 8917. doi:10.1038/s41598-021-88272-x
Peer Reviewed verified by ORBi

Costa Monteiro Moreira, G., Tang, L., Dupont, S., Young-Lim, L., Harland, C., Karim, L., Coppieters, W., Georges, M., & Charlier, C. (2021). LIVE (EPI)GENOMIC BATTLE BETWEEN UNFIXED TRANSPOSABLE ELEMENTS AND THEIR COGNATE piRNA CLUSTERS IN CATTLE TESTES [Paper presentation]. The Biology of Genomes.

Reynolds, E. G. M., Neeley, C., Lopdell, T. J., Keehan, M., Dittmer, K., Harland, C. S., Couldrey, C., Johnson, T. J. J., Tiplady, K., Worth, G., Walker, M., Davis, S. R., Sherlock, R. G., Carnie, K., Harris, B. L., Charlier, C., Georges, M., Spelman, R. J., Garrick, D. J., & Littlejohn, M. D. (2021). Non-additive association analysis using proxy phenotypes identifies novel cattle syndromes. Nature Genetics, 53 (7), 949-954. doi:10.1038/s41588-021-00872-5
Peer Reviewed verified by ORBi

Bonaguro, L., Köhne, M., Schmidleithner, J., Warnat-Herresthal, S., Horne, A., Kern, P., Günther, P., Ter Horst, R., Jaeger, M., Rahmouni, S., Georges, M., Falk, C. S., Li, Y., Mass, E., Beyer, M., Joosten, L. A. B., Netea, M. G., Ulas, T., Schultze, J. L., & Aschenbrenner, A. C. (21 December 2020). CRELD1 modulates homeostasis of the immune system in mice and humans. Nature Immunology, 12, 1517-1527. doi:10.1038/s41590-020-00811-2
Peer Reviewed verified by ORBi

Lee, Y.-L., Takeda, H., Costa Monteiro Moreira, G., Karim, L., Bosse, M., Bouwan, A., Mullaart, E., Coppieters, W., Georges, M., Druet, T., & Charlier, C. (02 December 2020). Fine resolution CNV catalogue from deeply sequenced cattle genomes [Paper presentation]. EAAP annual meeting.

Tang, L., Harland, C., Durkin, K., Artesi, M., Costa Monteiro Moreira, G., Karim, L., Deckers, M., Mullaart, E., Coppieters, W., Georges, M., & Charlier, C. (06 October 2020). INTER-INDIVIDUAL VARIATION OF DE NOVO ERV TRANSPOSITION RATE IN THE CATTLE GERMLINE [Poster presentation]. Transposable Elements, United States.

Koshmanova, E., Muto, V., Jaspar, M., Meyer, F., Grignard, M., Hammad, G., Berthomier, C., Brandewinder, M., Luxen, A., Degueldre, C., Salmon, E., Phillips, C., Posthuma, D., Georges, M., Schmidt, C., Maquet, P., van Someren, E., & Vandewalle, G. (22 September 2020). Higher polygenic risk for insomnia is associated with lower delta power during habitual sleep in young individuals without sleep disorders [Poster presentation]. 25th Congress of the European Sleep Research Society (ESRS) 2020.
Peer reviewed

Vuckovic, D., Bao, E. L., Akbari, P., Lareau, C. A., Mousas, A., Jiang, T., Chen, M.-H., Raffield, L. M., Tardaguila, M., Huffman, J. E., Ritchie, S. C., Megy, K., Ponstingl, H., Penkett, C. J., Albers, P. K., Wigdor, E. M., Sakaue, S., Moscati, A., Manansala, R., ... Soranzo, N. (03 September 2020). The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell, 182 (5), 1214 - 1231.e11. doi:10.1016/j.cell.2020.08.008
Peer Reviewed verified by ORBi

Coppieters, W., Karim, L., & Georges, M. (August 2020). SNP-based quantitative deconvolution of biological mixtures: application to the detection of cows with subclinical mastitis by whole-genome sequencing of tank milk. Genome Research, 30 (8), 1201 - 1207. doi:10.1101/gr.256172.119
Peer Reviewed verified by ORBi

Artesi, M., Tamma, N., Deckers, M., Karim, L., Coppieters, W., Van den Broeke, A., Georges, M., Charlier, C., & Durkin, K. (2020). Colour-sidedness in Gloucester cattle is associated with a complex structural variant impacting regulatory elements downstream of KIT. Animal Genetics. doi:10.1111/age.12932
Peer Reviewed verified by ORBi

GEORGES, A., Lavergne, A., Mandai, M., Lepiemme, F., Karim, L., Demeulenaere, L., Aguilar Ortmans, D., Schyns, M., Nguyen, L., RAKIC, J.-M., Takahashi, M., Georges, M., & Takeda, H. (2020). Combined analysis of single cell RNA-Seq and ATAC-Seq data reveals putative regulatory toggles operating in native and iPS-derived retina. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/292544. doi:10.1101/2020.03.02.972497

Klarić, L., Tsepilov, Y. A., Stanton, C. M., Mangino, M., Sikka, T. T., Esko, T., Pakhomov, E., Salo, P., Deelen, J., McGurnaghan, S. J., Keser, T., Vučković, F., Ugrina, I., Krištić, J., Gudelj, I., Štambuk, J., Plomp, R., Pučić-Baković, M., Pavić, T., ... Hayward, C. (2020). Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases. Science Advances, 6 (8), 0301. doi:10.1126/sciadv.aax0301
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Rosewick, N.* , Hahaut, V.* , Durkin, K., Artesi, M., Karpe, S., Wayet, J., Griebel, P., Arsic, N., Marçais, A., Hermine, O., Burny, A., Georges, M., & Van den Broeke, A. (2020). An Improved Sequencing-Based Bioinformatics Pipeline to Track the Distribution and Clonal Architecture of Proviral Integration Sites. Frontiers in Microbiology, 11, 587306. doi:10.3389/fmicb.2020.587306
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* These authors have contributed equally to this work.

Zhang, J., Kadri, N. K., Mullaart, E., Spelman, R., Fritz, S., Boichard, D., Charlier, C., Georges, M., & Druet, T. (2020). Genetic architecture of individual variation in recombination rate on the X chromosome in cattle. Heredity, 125 (5), 304-316. doi:10.1038/s41437-020-0341-9
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Muto, V., Koshmanova, E., Ghaemmaghami, P., Jaspar, M., Meyer, C., Elansary, M., Van Egroo, M., Chylinski, D., Berthomier, C., Brandewinder, M., Mouraux, C., Schmidt, C., Hammad, G., Coppieters, W., Ahariz, N., Degueldre, C., Luxen, A., Salmon, E., Phillips, C., ... Vandewalle, G. (2020). Alzheimer s disease genetic risk and sleep phenotypes: association with more slow-waves and daytime sleepiness. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/246837.

Costa Monteiro Moreira, G., Tang, L., Dupont, S., Harland, C., Karim, L., Coppieters, W., Georges, M., & Charlier, C. (2020). BIRTH OF POLYMORPHIC PIRNA CLUSTERS DRIVEN BY TRANSPOSABLE ELEMENT INSERTIONS IN THE MALE CATTLE GERMLINE [Poster presentation]. Transposable Elements Meeting.

De Koster, J., Salavati, M., Grelet, C., Crowe, M. A., Matthews, E., O'Flaherty, R., Opsomer, G., Foldager, L., Hostens, M., McLoughlin, N., Fahey, A., Santoro, A., Byrne, C., Rudd, P., Hallinan, S., Wathes, C., Cheng, Z., Fouladi, A., Pollott, G., ... GplusE. (April 2019). Corrigendum to “Prediction of metabolic clusters in early-lactation dairy cows using models based on milk biomarkers”. Journal of Dairy Science, 102 (4), 3778. doi:10.3168/jds.2019-102-4-3778

Sharapov, S. Z., Tsepilov, Y. A., Klaric, L., Mangino, M., Thareja, G., Shadrina, A. S., Simurina, M., Dagostino, C., Dmitrieva, J. B., Vilaj, M., Vuckovic, F., Pavic, T., Stambuk, J., Trbojevic-Akmacic, I., Kristic, J., Simunovic, J., Momcilovic, A., Campbell, Doherty, M., ... Aulchenko, Y. S. (2019). Defining the genetic control of human blood plasma N-glycome using genome-wide association study. Human Molecular Genetics, 28 (12), 2062-2077. doi:10.1093/hmg/ddz054
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Georges, M., Charlier, C., & Hayes, B. (2019). Harnessing genomic information for livestock improvement. Nature Reviews. Genetics. doi:10.1038/s41576-018-0082-2
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Artesi, M., Hahaut, V., Ashrafi, F., Marcais, A., Hermine, O., Griebel, P., Arsic, N., van der Meer, F., Burny, A., Bron, D., Charlier, C., Georges, M., Van den Broeke, A., & Durkin, K. (2019). Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the associated provirus in thousands of cells with long reads 558130. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/237583. doi:10.1101/558130

Weersma, R., Barrett, J., Vermeire, S., Xavier, R., Anderson, C., Wijmenga, C., Daly, M., Alm, E., Raes, J., Huttenhower, C., Stappenbeck, T., Netea, M., Kaser, A., Franke, A., McGovern, D., Colombel, J., van den Brink, G., Uhlig, H., Georges, M., ... Moutsianas, L. (November 2018). Multiomics Analyses to Deliver the Most Effective Treatment to Every Patient With Inflammatory Bowel Disease. Gastroenterology, 155 (5), 1-e4. doi:10.1053/j.gastro.2018.07.039
Peer Reviewed verified by ORBi

Georges, M., Van den Broeke, A., Durkin, K., Artesi, M., Hahaut, V., & Rosewick, N. (11 October 2018). MONITORING METHOD FOR ADULT T-CELL LEUKEMIA/LYMPHOMA (ATL).

Ghaemmaghami Tabrizi, P., Muto, V., Jaspar, M., Meyer, C., Elansary, M., Van Egroo, M., Berthomier, C., Lambot, E., Brandewinder, M., Luxen, A., Degueldre, C., Salmon, E., Archer, S., Phillips, C., Dijk, D.-J., Georges, M., Maquet, P., & Vandewalle, G. (September 2018). Volume of subcortical brain areas is associated with sleep macrostructure in healthy young individuals [Paper presentation]. 24th Congress of the European Sleep Research Society, Basel, Switzerland.

Ghaemmaghami Tabrizi, P., Muto, V., Jaspar, M., Meyer, C., Elansary, M., Van Egroo, M., Berthomier, C., Lambot, E., Brandewinder, M., Luxen, A., Degueldre, C., Salmon, E., Archer, S., Phillips, C., Dijk, D.-J., Visscher, P., Posthuma, D., Van Someren, E., Georges, M., ... Vandewalle, G. (September 2018). The genetic liability for insomnia is associated with the number of awakenings during sleep in young and healthy individuals [Paper presentation]. 24th Congress of the European Sleep Research Society, Basel, Switzerland.

Ghaemmaghami Tabrizi, P., Muto, V., Jaspar, M., Meyer, C., Elansary, M., Van Egroo, M., Berthomier, C., Lambot, E., Devillers, J., Brandewinder, M., Luxen, A., Degueldre, C., Salmon, E., Collette, F., Archer, S., Phillips, C., Dijk, D.-J., Georges, M., Maquet, P., & Vandewalle, G. (September 2018). Predicted gene expression in the brain is associated with sleep macrostructure in healthy young individuals [Paper presentation]. 24th Congress of the European Sleep Research Society, Basel, Switzerland.

Waage, J., Standl, M., Curtin, J. A., Jessen, L. E., Thorsen, J., Schoettler, N., Flores, C., The 23andMe Research Team, AAGC collaborators, Abdellaoui, A., Ahluwalia, T. S., Alves, A., Amaral, A. F. S., Anto, J. M., Arnold, A., Barreto-Luis, A., Baurecht, H., Beijserveldt, T., Bleecker, E. R., ... D-Bonnelykke, K. (August 2018). Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nature Genetics, 50 (8), 1072-1080. doi:10.1038/s41588-018-0157-1
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Rapino, F., Delaunay, S., Rambow, F., Zhou, Z., Tharun, L., De Tullio, P., Sin, O., Shostak, K., Schmitz, S., Piepers, J., Guesquière, B., Karim, L., Charloteaux, B., Jamart, D., Florin, A., Lambert, C., RORIVE, A., JERUSALEM, G., Leucci, E., ... Close, P. (28 June 2018). Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature, 558, 605-609. doi:10.1038/s41586-018-0243-7
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Muraille, E., de Kerchove d'Exaerde, A., Blanpain, C., Vassart, G., Parmentier, M., Moser, M., Oberdan, L., Vanderhaegen, P., Vanduffel, W., Vogels, R., Tissir, F., Bureau, F., Hanson, J., Drion, P., Georges, M., Seutin, V., Ris, L., & De Backer, O. (2018). L'expérimentation animale ne se fait pas en dehors de tout contrôle (OPINION). La Libre Belgique.

Kadri, N. K., Harland, C., Charlier, C., Karim, L., Cambisano, N., Deckers, M., Mullaart, E., Coppieters, W., Georges, M., & Druet, T. (2018). High resolution mapping of cross-over events in cattle using NGS data. In Proceedings of the World Congress on Genetics Applied to Livestock Production.
Peer reviewed

Hahaut, V., Rosewick, N., Artesi, M., Durkin, K., Burny, A., Bron, D., Georges, M., & Van den Broeke, A. (02 February 2018). Improving the bioinformatics analysis of HTS clonality data in virus-induced leukemia [Poster presentation]. Télévie Cancer Seminar 2018.

Momozawa, Y., Dmitrieva, J. B., Theatre, E., Deffontaine, V., Rahmouni, S., Charloteaux, B., Crins, F., Elansary, M., Gori, A.-S., LECUT, C., Mariman, R., Mni, M., Oury, C., Altukhov, I., Alexeev, D., Aulchenko, Y., Amininejad, L., van der Meulen-de Jong, A. E., van der Woude, C. J., ... Georges, M. (2018). IBD risk loci are enriched in multigenic regulatory modules encompassing causative genes. Nature Communications. doi:10.1038/s41467-018-04365-8
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Amininejad, L.* , Charloteaux, B.* , Theatre, E., Liefferinckx, C., Dmitrieva, J., Hayard, P., Muls, V., Maisin, J.-M., Schapira, M., Ghislain, J.-M., Closset, P., Talib, M., Abramowicz, M., Momozawa, Y., Deffontaine, V., Crins, F., Mni, M., Karim, L., Cambisano, N., ... Franchimont, D.*. (2018). Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's Disease. Gastroenterology, 154 (8), 2165-2177. doi:10.1053/j.gastro.2018.02.028
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* These authors have contributed equally to this work.

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Harland, C., Charlier, C., Karim, L., Cambisano, N., Deckers, M., Mni, M., Mullaart, E., Coppieters, W., & Georges, M. (2017). Frequency of mosaicism points towards mutation-prone early cleavage cell divisions in cattle. BioRxiv. doi:10.1101/079863

Durkin, K., Artesi, M., Hahaut, V., Rosewick, N., Griebel, P., Arsic, N., Burny, A., Georges, M., & Van den Broeke, A. (21 September 2017). The Landscape And Evolution Of Somatic Mutations In Bovine Leukemia Virus Induced Tumors [Paper presentation]. Animal Genetics & Diseases, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.

Druet, T., Sartelet, A., Hubin, X., Tamma, N., Georges, M., & Charlier, C. (August 2017). Identification and management of recessive genetic defects in Belgian Blue beef cattle [Paper presentation]. 68th Annual Meeting of the European Federation of Animal Science, Tallinn, Estonia.

Durkin, K., Artesi, M., Hahaut, V., Rosewick, R., Griebel, P., Arsic, N., Burny, A., Georges, M., & Van den Broeke, A. (July 2017). Somatic Structural And Numerical Aberrations In Bovine Leukemia Virus Induced Tumors [Poster presentation]. 36th International Society for Animal Genetics Conference, Dublin, Ireland.

Rosewick, N.* , Durkin, K.* , Artesi, M.* , Marçais, A., Hahaut, V., Griebel, P., Avettand-Fenoel, V., Burny, A., Charlier, C., Hermine, O., Georges, M., & Van den Broeke, A. (23 May 2017). Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis. Nature Communications, 8. doi:10.1038/ncomms15264
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* These authors have contributed equally to this work.

Hahaut, V., Artesi, M., Durkin, K., Rosewick, N., Griebel, P., Natasa, A., Burny, A., Georges, M., & Van den Broeke, A. (08 March 2017). Investigating non-coding viral transcripts in Bovine Leukemia Virus induced leukemia [Poster presentation]. 18th International Conference on Human Retrovirology: HTLV and Related Viruses, Tokyo, Japan.

Durkin, K., Artesi, M., Hahaut, V., Rosewick, N., Griebel, P., Arsic, N., Burny, A., Georges, M., & Van den Broeke, A. (March 2017). Structural And Numerical Somatic Changes In BLV Induced Tumors [Poster presentation]. 18th International Conference on Human Retorovirology HTLV and Related Viruses, Tokyo, Japan.

Ghisdal, L., Baron, C., Lebranchu, Y., Viklicky, O., Konarikova, A., Naesens, A., Kuypers, D., Dinic, M., Alamartine, E., Touchard, G., Antoine, T., Essig, M., Rerolle, J. P., Merville, P., Taupin, J. L., Le Meur, Y., Grall - Jezequel, A., Glowacki, F., Noel, C., ... Abramowicz M. (2017). Genome-wide Association Study of Acute Renal Graft Rejection. American Journal of Transplantation, 17 (1), 201-2019. doi:10.1111/ajt.13912
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Artesi, M., Marcais, A., Durkin, K., Rosewick, N., Hahaut, V., Suarez, F., Trinquand, A., Lhermitte, L., Asnafi, V., Avettand-Fenoel, V., Burny, A., Georges, M., Hermine, O., & Van den Broeke, A. (2017). Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia, 31 (11), 2532-2535. doi:10.1038/leu.2017.260
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Marçais, A., Artesi, M., Durkin, K., Hahaut, V., Suarez, F., Sibon, D., Cheminand, M., Delarue, R., Lhermitte, L., Asnafi, V., Avettand Fenoel, V., Georges, M., Van den Broeke, A., & Hermine, O. (2017). Improved high throughput DNA-seq based mapping of HTLV-1 integration sites: a tool to define response to treatment, ATL prognosis and guide therapeutic strategies [Paper presentation]. 18th international conference on human retrovirology - HTLV and related viruses, Tokyo, Japan.

Huang, H.* , Fang, M.* , Jostins, L.* , Umicevic - Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J. B., DOCAMPO MARTINEZ, E., Elansary, M., Farh, K. K.-H., Franke, A., Gori, A.-S., Goyette, P., ... Barrett, J. C.*. (2017). Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature, 547 (7662), 173-178. doi:10.1038/nature22969
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* These authors have contributed equally to this work.

Fodil, N., Moradin, N., Leung, V., Olivier, J.-F., Radovanovic, I., Jeyakumar, T., Flores Molina, M., McFarquhar, A., Cayrol, R., Bozec, D., Shoukry, N. H., Kubo, M., Dimitrieva, J., Louis, E., Theatre, E., Dahan, S., Momozawa, Y., Georges, M., Yeretssian, G., & Gros, P. (2017). CCDC88B is required for pathogenesis of inflammatory bowel disease. Nature Communications, 8 (1), 932. doi:10.1038/s41467-017-01381-y
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Charlier, C., Li, W., Harland, C., Littlejohn, M., Coppieters, W., Creagh, F., Davis, S., Druet, T., Faux, P., Guillaume, F., Karim, L., Keehan, M., Kadri, N. K., Tamma, N., Spelman, R., & Georges, M. (19 September 2016). NGS- based reverse genetic screen for common embryonic lethal mutations compromising fertility in livestock. Genome Research, 26:1-9. doi:10.1101/gr.207076.116
Peer Reviewed verified by ORBi

Fang, M., & Georges, M. (2016). BayesFM: a software program to fine-map multiple causative variants in GWAS identified risk loci. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/212271. doi:10.1101/067801

Sartelet, A., Harland, C., Tamma, N., Karim, L., Bayrou, C., Li, W., Ahariz, N., Coppieters, W., Georges, M., & Charlier, C. (07 July 2016). A stop-gain in the laminin, alpha 3 gene causes recessive junctional epidermolysis bullosa in Belgian Bleu cattle [Paper presentation]. XXIXth World Buiatrics Congress, Dublin, Ireland.

Kadri, N. K., Harland, C., Faux, P., Cambisano, N., Karim, L., Coppieters, W., Fritz, S., Mullaart, E., Boichard, D., Spelman, R., Charlier, C., Georges, M., & Druet, T. (15 June 2016). Sequence-based association analysis identifies coding and non-coding variants in HFM1, MLH3, MSH4, MSH5, RNF212 and RNF212B with large effects on male and female recombination rate in cattle [Poster presentation]. 5th International Congress on Quantitative Genetics, Madison, United States.

Durkin, K., Rosewick, N., Artesi, M., Hahaut, V., Griebel, P., Arsic, N., Burny, A., Georges, M., & Van den Broeke, A. (21 May 2016). Identification and characterization of novel bovine leukemia virus (BLV) antisense transcripts in leukemic and pre-leukemic clones [Paper presentation]. HTLV European Research Network Meeting 2016, Bucharest, Romania.

Kadri, N. K., Harland, C., Faux, P., Cambisano, Karim, L., Coppieters, W., Fritz, S., Mullaart, E., Boichard, D., Spelman, R., Charlier, C., Georges, M., & Druet, T. (11 May 2016). HIGHER MALE THAN FEMALE RECOMBINATION RATE LARGELY CONTROLLED BY MISSENSE VARIANTS IN RNF212, MLH3, HFM1, MSH5 AND MSH4 IN CATTLE [Poster presentation]. Cold Spring Harbor meetings: the biology of genomes.

Bodea, C., Neale, B., Ripke, S., The International IBD Genetics Consortium, Daly, M., Roeder, K., & Georges, M. (Other coll.). (05 May 2016). A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies. American Journal of Human Genetics, 98 (5), 857-868. doi:10.1016/j.ajhg.2016.02.025
Peer Reviewed verified by ORBi

Jaspar, M., Muto, V., Meyer, C., Coppieters, W., Georges, M., Maquet, P., & Collette, F. (18 March 2016). The impact of dopaminergic genes on inhibitory processes and cognitive control [Poster presentation]. Joint Meeting of the British Neuropsychological Society with la Société de Neuropsychologie de Langue Française, Londres, United Kingdom.

Li, W.* , Sartelet, A.* , Tamma, N., Coppieters, W., Georges, M., & Charlier, C. (February 2016). Reverse genetic screen for loss-of-function mutations uncovers a frame-shifting deletion in the melanophilin gene accountable for a distinctive coat-color in Belgian Blue Cattle. Animal Genetics, 47 (1), 110-113. doi:10.1111/age.12383
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Durkin, K., Rosewick, N., Artesi, M., Hahaut, V., Griebel, P., Arsic, N., Burny, A., Georges, M., & Van den Broeke, A. (2016). Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional interaction with viral microRNAs. Retrovirology, 13 (1), 33. doi:10.1186/s12977-016-0267-8
Peer Reviewed verified by ORBi

Artesi, M., Durkin, K., Rosewick, N., Georges, M., & Van den Broeke, A. (2016). Improving the methodology for high throughput mapping of proviral integration sites [Paper presentation]. The HTLV european research network meeting, Bucharest, Romania.

Kadri, N. K., Harland, C., Faux, P., Cambisano, N., Karim, L., Coppieters, W., Fritz, S., Mullaart, E., Baurain, D., Boichard, D., Spelman, R., Charlier, C., Georges, M., & Druet, T. (2016). Coding and noncoding variants in HFM1, MLH3, MSH4, MSH5, RNF212, and RNF212B affect recombination rate in cattle. Genome Research, 26 (10), 1323-1332. doi:10.1101/gr.204214.116
Peer Reviewed verified by ORBi

Xu, X., Ectors, F., Davis, E. E., Pirottin, D., Cheng, H., Farnir, F., Hadfield, T., Cockett, N., Charlier, C., Georges, M., & Takeda, H. (16 October 2015). Ectopic Expression of Retrotransposon-Derived PEG11/RTL1 Contributes to the Callipyge Muscular Hypertrophy. PLoS ONE, 10 (10), 0140594. doi:10.1371/journal.pone.0140594
Peer Reviewed verified by ORBi

Sartelet, A.* , Harland, C.* , Tamma, N., Karim, L., Bayrou, C., Li, W., Ahariz, N., Coppieters, W., Georges, M., & Charlier, C. (October 2015). A stop-gain in the laminin, alpha 3 gene causes recessive junctional epidermolysis bullosa in Belgian Blue cattle. Animal Genetics, 46 (5), 566-570. doi:10.1111/age.12342
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Liu, J., Van Sommeren, S., Huang, H., Ng, S. C., International IBD Genetics Consortium, Weersma, R., & Georges, M. (Other coll.). (September 2015). Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nature Genetics, 47 (9), 979-986. doi:10.1038/ng.3359
Peer Reviewed verified by ORBi

Durkin, K., Artesi, M., Rosewick, N., Marçais, A., Hermine, O., Georges, M., & Van den Broeke, A. (28 August 2015). Improving the methodology for the detection of proviral integration sites in the host genome via high throughput sequencing. Retrovirology, 12 (1).
Peer Reviewed verified by ORBi

Rosewick, N., Durkin, K., Marçais, A., Artesi, M., Hermine, O., Charlier, C., Georges, M., & Van den Broeke, A. (28 August 2015). HTLV-1/BLV antisense-RNA dependent host gene perturbation in pre-leukemic and leukemic clones. Retrovirology, 12 (1).
Peer Reviewed verified by ORBi

Elansary, M., Stinckens, A., Ahariz, N., Cambisano, N., Coppieters, W., Grindflek, E., van Son, M., Buys., N., & Georges, M. (2015). On the use of the transmission disequilibrium test to detect pseudo-autosomal variants affecting traits with sex-limited expression. Animal Genetics. doi:10.1111/age.12296
Peer Reviewed verified by ORBi

Docampo Martínez, E., Fang, M., Dmitrieva, J. B., Theatre, E., Elansary, M., Mariman, R., Gori, A.-S., Mini, M., Crins, F., Coppieters, W., LOUIS, E., & Georges, M. (05 May 2015). Prioritizing likely causative genes in GWAS identified risk loci for immune-mediated inflammatory disorders using cell-type specific eQTL information [Poster presentation]. cold spring harbor laboratory THE BIOLOGY OF GENOMES.

Kadri, N. K., Harland, C., Coppieters, W., Fritz, S., Boichard, D., Spelman, R., Schrooten, C., Mullaart, E., Charlier, C., Georges, M., & Druet, T. (05 May 2015). Higher male than female recombination rate in cattle is controlled by genetic variants effective in both sexes [Poster presentation]. Cold Spring Harbord meeting - The biology of genomes.

Durkin, K., Artesi, M., Rosewick, N., Georges, M., & Van den Broeke, A. (May 2015). Improving proviral integration site detection with high throughput sequencing [Poster presentation]. The biology of genomes, Cold Spring Harbor, United States - New York.

Trivellin, G., Daly, A., Faucz, F., Yuan, B., Rostomyan, L., Larco, D., Schernthaner-Reiter, M., Szarek, E., Leal, L., CABERG, J.-H., CASTERMANS, E., Villa, C., Dimopoulos, A., Chittiboina, P., Xekouki, P., Shah, N. S., Metzger, D., Lysy, P., Ferrante, E., ... Stratakis, C. (2015). X-Linked acro-gigantism (X-LAG) due to microduplications of chromosome Xq26 : A new disorder and implications for acromegaly. In Abstract book - ENDO 2015.

Kadri, N. K., Harland, C., Coppieters, W., Fritz, S., Boichard, D., Spelman, R., Schrooten, C., Mullaart, E., Charlier, C., Georges, M., & Druet, T. (February 2015). Scanning the genome for QTL affecting the recombination process in the male and female cattle germline [Poster presentation]. Gordon Research Conference: Quantitative Genetics & Genomics, Lucca, Italy.

Laitat, M., Veillat, E., Van Cauwenberge, H., GEORIS, P., Busoni, V., Sartelet, A., Elansary, M., & Georges, M. (February 2015). Lordose et/ou xyphose chez le porc : mise à l’épreuve de l’hypothèse héréditaire [Poster presentation]. Journées de la Recherche Porcine, Paris, France.

Goyette, P., Boucher, G., Mallon, D., Ellinghaus, E., Jostins, L., Huang, H., Ripke, S., Gusareva, E., Annese, V., Hauser, S. L., Oksenberg, J. R., Thomsen, I., Leslie, S., Theatre, E., Georges, M., Louis, E., Daly, M. J., Van Steen, K., Duerr, R. H., ... Rioux, J. D. (05 January 2015). High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nature Genetics, 47 (2), 172-9. doi:10.1038/ng.3176
Peer Reviewed verified by ORBi

Cleynen, I., Konings, P., Robberecht, C., Laukens, D., Amininejad, L., Théâtre, E., Machiels, K., Arijs, I., Rutgeerts, P., Louis, E., Franchimont, D., De Vos, M., Van Steen, K., Georges, M., Moreau, Y., Vermeesch, J., & Vermeire, S. (2015). Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease. Inflammatory Bowel Diseases. doi:10.1097/MIB.0000000000000623
Peer Reviewed verified by ORBi

Druet, T., & Georges, M. (2015). LINKPHASE3: an improved pedigree-based phasing algorithm robust to genotyping and map errors. Bioinformatics, 31 (10), 1677-9. doi:10.1093/bioinformatics/btu859
Peer Reviewed verified by ORBi

Sartelet, A.* , Li, W.* , Pailhoux, E., Richard, C., Tamma, N., Karim, L., Fasquelle, C., Druet, T., Coppieters, W., Georges, M., & Charlier, C. (2015). Genome-wide next-generation DNA and RNA sequencing reveals a mutation that perturbs splicing of the phosphatidylinositol glycan anchor biosynthesis class H gene (PIGH) and causes arthrogryposis in Belgian Blue cattle. BMC Genomics, 16 (316). doi:10.1186/s12864-015-1528-y
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Cheng, H., Xu, X., Hadfield, T., Cockett, N., Charlier, C., Georges, M., & Takeda, H. (30 October 2014). Experimental evaluation does not reveal a direct effect of microRNA from the callipyge locus on DLK1 expression. BMC Genomics, 15, 944. doi:10.1186/1471-2164-15-944
Peer Reviewed verified by ORBi

Abos, R., Coussé, A., Sarre, C., Hubin, X., Boccart, C., Losson, B., Saegerman, C., Claerebout, E., Georges, M., & Buys, N. (17 October 2014). Phenotyping Belgian Blue cattle for their susceptibility to psoroptic mange [Poster presentation]. First Edition of The Farah Day, Liège, Belgium.

Druet, T., Ahariz, N., Cambisano, N., Tamma, N., Michaux, C., Coppieters, W., Charlier, C., & Georges, M. (17 October 2014). Selection in action: dissecting the molecular underpinnings of the increasing muscle mass of Belgian Blue Cattle [Paper presentation]. First FARAH-day.

Druet, T., & Georges, M. (22 August 2014). Pedigree-based haplotype reconstruction, identification of cross-overs and detection of map and genotyping errors using PHASEBOOK [Paper presentation]. 10 th World Congress of Genetics Applied to Livestock Production.

Georges, M. (August 2014). Towards sequence-based genomic selection of cattle. Nature Genetics, 46 (8), 807 - 809. doi:10.1038/ng.3048
Peer Reviewed verified by ORBi

Sartelet, A., Chapon, S., Fasquelle, C., Tamma, N., Georges, M., & Charlier, C. (27 June 2014). AN INTEGRATED APPROACH FOR THE MANAGEMENT OF INHERITED DISORDERS IN BELGIAN BLUE CATTLE BREED IN BELGIUM [Paper presentation]. Congreso Internacional ANEMBE de Medecina Bovina & IX ECBHM Symposium, Oviedo, Spain.

Durkin, K., Rosewick, N., Momont, M., Thys, W., Burny, A., Georges, M., & Van den Broeke, A. (June 2014). Identification of two noncoding antisense transcripts in BLV and their interaction with the BLV encoded miRNAs [Paper presentation]. HERN meeting, Rome, Italy.

Rosewick, N., Durkin, K., Thys, W., Marçais, A., Hermine, O., Burny, A., Georges, M., & Van den Broeke, A. (June 2014). Exploring the Deltaretrovirus Tumor Transcriptome: Lessons from RNA-Seq [Paper presentation]. HERN meeting, Rome, Italy.

Mariman, R., Coppieters, W., Elansary, M., Karim, L., Crins, F., Mni, M., Gori, A.-S., Aoun, N., Docampo Martínez, E., Dmitrieva, J. B., Fang, M., Theatre, E., Eppe, G., & Georges, M. (24 April 2014). Identification of molecular components of the host-microbiota-connectome by using "Omics Approaches" [Poster presentation]. BeMGI.

Docampo Martínez, E., Theatre, E., Dmitrieva, J. B., Elansary, M., Mariman, R., Mni, M., Crins, F., Gori, A.-S., Fang, M., LOUIS, E., & Georges, M. (24 April 2014). Identifying Inflammatory Bowel Disease causative genes through trans-eQTLs mapping within GWAS loci [Poster presentation]. BeMGI.

Gori, A.-S., LECUT, C., Theatre, E., Momozawa, Y., Docampo Martínez, E., Mariman, R., Dmitrieva, J. B., Elansary, M., Charloteaux, B., Defontaine, V., Mni, M., Crins, F., LOUIS, E., Georges, M., & Oury, C. (24 April 2014). Combined use of GWAS and eQTL information to identify genes controlling platelet biology [Poster presentation]. BeMGI. doi:10.13140/RG.2.1.4044.9763

Sjöstrand, K., Wess, G., Ljungvall, I., Häggström, J., Merveille, A.-C., Wiberg, M., Gouni, V., Lundgren Willesen, J., Hanas, S., Lequarré, A.-S., Mejer Sorensen, L., Wolf, J., Tiret, L., Kierczak, M., Forsberg, S., Mc Entee, K., Battaille, G., Seppälä, E., Lindblad-Toh, K., ... Höglund, K. (March 2014). Breed differences in natriuretic peptides in healthy dogs. Journal of Veterinary Internal Medicine, 28, 451. doi:10.1111/jvim.12310
Peer Reviewed verified by ORBi

Durkin, K., Rosewick, N., Momont, M., Thys, W., Burny, A., Georges, M., & Van den Broeke, A. (February 2014). Identification of two antisense transcripts in BLV and their interaction with BLV-encoded microRNAs [Poster presentation]. Keystone meeting Non-coding RNAs: towards mechanisms, Santa Fe, United States.

Durkin, K., Rosewick, N., Momont, M., Thys, W., Burny, A., Georges, M., & Van den Broeke, A. (07 January 2014). Elucidating the role of Bovine Leukemia Virus encoded micro-RNAs. Retrovirology, 11 (1), 62.
Peer Reviewed verified by ORBi

Kumar Kadri, N., Sahana, G., Charlier, C., Iso-Touru, T., Guldbrandtsen, B., Karim, L., Sander Nielsen, U., Panitz, F., Pedersen Aamand, G., Schulman, N., Georges, M., Vilkki, J., Sandø Lund, M., & Druet, T. (January 2014). A 660-Kb Deletion with Antagonistic Effects on Fertility and Milk Production Segregates at High Frequency in Nordic Red Cattle: Additional Evidence for the Common Occurrence of Balancing Selection in Livestock. PLoS Genetics, 10 (1), 1004049. doi:10.1371/journal.pgen.1004049
Peer Reviewed verified by ORBi

Trivellin, G.* , Daly, A.* , Faucz, F. R., Yuan, B., Rostomyan, L., Larco, D. O., Schernthaner-Reiter, M. H., Szarek, E., Leal, L. F., CABERG, J.-H., CASTERMANS, E., Villa, C., Dimopoulos, A., Chittiboina, P., Xekouki, P., Shah, N. S., Metzger, D., Lysy, P. A., Ferrante, E., ... Stratakis, C. A.*. (2014). Gigantism and Acromegaly Due to Xq26 Microduplications and GPR101 Mutation. New England Journal of Medicine. doi:10.1056/NEJMoa1408028
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Druet, T., Ahariz, N., Cambisano, N., Tamma, N., Michaux, C., Coppieters, W., Charlier, C., & Georges, M. (2014). Selection in action: dissecting the molecular underpinnings of the increasing muscle mass of Belgian Blue Cattle. BMC Genomics, 15 (1), 796. doi:10.1186/1471-2164-15-796
Peer Reviewed verified by ORBi

Höglund, K., Lequarré, A.-S., Ljungvall, I., Mc Entee, K., Merveille, A.-C., Wiberg, M., Gouni, V., Lundgren Wilessen, J., Hanas, S., Wess, G., Mejer Sorensen, L., Tiret, L., Kierczak, M., Forsberg, S., Seppälä, E., Lindblad-Toh, K., Georges, M., Lohi, H., Chetboul, V., ... Häggström, J. (2014). Breed Differences in Concentrations of Neuroendocrines and Cortisol in Healthy Dogs. Journal of Veterinary Internal Medicine.
Peer Reviewed verified by ORBi

Laitat, M., Van Cauwenberge, H., Harmegnies, N., Georis, P., Busoni, V., Elansary, M., & Georges, M. (2014). Lordosis in pigs: testing the hereditary hypothesis [Poster presentation]. European Symposium of Porcine Health Management (ESPHM).

GEORGES, A., Cambisano, N., Ahariz, N., Karim, L., & Georges, M. (December 2013). A genome scan conducted in a multigenerational pedigree with convergent strabismus supports a complex genetic determinism. PLoS ONE, 8 (12), 83574. doi:10.1371/journal.pone.0083574
Peer Reviewed verified by ORBi

Sartelet, A., Li, W., Pailhoux Eric, Tamma, N., Karim, L., Fasquelle, C., Druet, T., Coppieters, W., Georges, M., & Charlier, C. (2013). A splice-acceptor site variant in the bovine PIGH gene causes glycosylphosphatidyl inositol deficiency and lethal arthrogryposis syndrome. In C. Bayrou, J.-F. Cabaraux, C. Delguste, T. Jauniaux, A. Sartelet, ... D. Votion (Eds.), Proccedings of the 3rd Scientific Meetingof the Faculty of Veterinary Medecine (pp. 27). Liège, Belgium: Presses de la Faculté de Médecine Vétérinaire.
Peer reviewed

Sartelet, A., Li, W., Pailhoux, E., Tamma, N., Karim, L., Fasquelle, C., Druet, T., Coppieters, W., Georges, M., & Charlier, C. (29 August 2013). A splice-acceptor site variant in the bovine PIGH gene causes glycosylphosphatidyl inositol deficiency and lethal arthrogryposis syndrome [Poster presentation]. Buiatrissima - 8th ECBHM Symposium, Berne, Switzerland.

Cross-Disorder Group of the Psychiatric Genomics Consortium*, Georges, M., & International Inflammatory Bowel Disease Genetics Consortium (IIBDGC). (11 August 2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics, 45 (9), 984-94. doi:10.1038/ng.2711
Peer Reviewed verified by ORBi

Georges, M., Coppieters, W., & Blard, G. (06 June 2013). Method for identifying cows with mastitis by bulk genotyping of tank milk.

Liu, J., Hov, J., Folseraas, T., Ellinghaus, E., Rushbrook, S. M., The International IBD Genetics Consortium, & Georges, M. (Other coll.). (June 2013). Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nature Genetics, 45 (6), 670-5. doi:10.1038/ng.2616
Peer Reviewed verified by ORBi

Georges, M., Blard, G., & Coppieters, W. (29 May 2013). Method for identifying cows with mastitis by bulk genotyping of tank milk.

Van Laere, A.-S., Maglie, S., & Georges, M. (05 May 2013). Evolution of the mammalian pseudoautosomal boundary [Poster presentation]. GIGA day.

Berry, S., Coppieters, W., Davis, S., Burrett, A., Thomas, N., Palmer, D., Kelly, V., Obolonkin, V., Sanders, K., Spelman, R., Georges, M., Lehnert, K., & Snell, R. (March 2013). A triad of highly divergent polymeric immunoglobulin receptor (PIGR) haplotypes with major effect on IgA concentration in bovine milk. PLoS ONE, 8 (3), 57219. doi:10.1371/journal.pone.0057219
Peer Reviewed verified by ORBi

Druet, T., Ahariz, N., Cambisano, N., Géron, S., Coppieters, W., Charlier, C., & Georges, M. (February 2013). Scan for selective sweeps associated with muscular devolpment in Belgian Blue beef cattle [Poster presentation]. The Quantitative Genetics & Genomics Gordon Research Conference.

Sartelet, A., Li, W., Pailhoux, E., Tamma, N., Karim, L., Fasquelle, C., Druet, T., Coppieters, W., Georges, M., & Charlier, C. (28 January 2013). A splice-acceptor site variant in the bovine PIGH gene causes glycosylphosphatidyl inositol deficiency and lethal arthrogryposis syndrome [Poster presentation]. GIGA-DAY, Liège, Belgium.

Rosewick, N., Momont, M., Durkin, K., Takeda, H., Caiment, F., Cleuter, Y., Vernin, C., Mortreux, F., Wattel, E., Burny, A., Georges, M., & Van den Broeke, A. (2013). Deep sequencing reveals abundant non-canonical retroviral microRNAs in B-cell leukemia/lymphoma. Proceedings of the National Academy of Sciences of the United States of America.
Peer Reviewed verified by ORBi

Schroyen, M., Goddeeris, B. M., Stinckens, A., Verhelst, R., Janssens, S., Cox, E., Georges, M., Niewold, T., & Buys, N. (2013). The effect of enterotoxigenic Escherichia coli F4ab,ac on early-weaned piglets: A gene expression study. Veterinary Immunology and Immunopathology, 152 (1-2), 87-92. doi:10.1016/j.vetimm.2012.09.027
Peer Reviewed verified by ORBi

Dupuis, M.-C., Zhang, Z., Durkin, K., Charlier, C., Lekeux, P., & Georges, M. (2013). Detection of copy number variants in the horse genome and examination of their association with recurrent laryngeal neuropathy. Animal Genetics. doi:10.1111/j.1365-2052.2012.02373.x
Peer Reviewed verified by ORBi

Beaudoin, M., Goyette, P., Boucher, G., International IBD Genetics Consortium, Lo, K. S., Rivas, M. A., Rioux, J., & Georges, M. (Other coll.). (2013). Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis. PLoS Genetics, 9 (9). doi:10.1371/journal.pgen.1003723
Peer Reviewed verified by ORBi

Sartelet, A., Stauber, T., Coppieters, W., Fasquelle, C., Druet, T., Zhang, Z., Ahariz, N., Cambisano, N., Jentsch, T., Georges, M., & Charlier, C. (19 October 2012). A missense mutation in the ClC-7 chloride channel causes hamartomas with osteopetrosis in cattle [Paper presentation]. 2nd FMC Scientific day, Liège, Belgium.

Littlejohn, M., Grala, T., Sanders, K., Walker, C., Waghorn, G., Macdonald, K., Coppieters, W., Georges, M., Spelman, R., Hillerton, E., Davis, S., & Snell, R. (October 2012). Genetic variation in PLAG1 associates with early life body weight and peripubertal weight and growth in Bos taurus. Animal Genetics, 43 (5), 591-4. doi:10.1111/j.1365-2052.2011.02293.x
Peer Reviewed verified by ORBi

Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Schumm, L. P., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., ... Cho, J. H. (October 2012). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature, 491 (7422), 119-24. doi:10.1038/nature11582
Peer Reviewed verified by ORBi

Sartelet, A.* , Klingbeil, P.* , Franklin, C., Fasquelle, C., Geron, S., Isacke, C., Georges, M., & Charlier, C. (October 2012). Allelic heterogeneity of Crooked Tail Syndrome: result of balancing selection? Animal Genetics, 43 (5), 604-607. doi:10.1111/j.1365-2052.2011.02311.x
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Georges, M. (2012). Impact of the High-Throughput Genotyping & Sequencing on the identification of Genes and Variants Undertyping Phenotypic Variation in Domestic Cattle. In J. Womack (Ed.), Bovine Genomics. Wiley.

Guillaume, F., Zhang, Z., Sartelet, A., Charlier, C., Georges, M., Farnir, F., & Druet, T. (20 June 2012). Development of a method for haplotype-based association analysis of binary traits in structured populations [Poster presentation]. 4th International Conference on Quantitative Genetics: Understanding Variation in Complex Traits, Edinburgh, United Kingdom.

Sartelet, A., Stauber, T., Druet, T., Fasquelle, C., Tamma, N., Ahariz, N., Cambisano, N., Coppieters, W., Jentsch, T., & Georges, M. (05 June 2012). A missense mutation in the ClC-7 chloride channel causes hamartomas with osteopetrosis in cattle [Paper presentation]. XXVIIth Wolrd Buiatrics Congress, Lisbonne, Portugal.

Zhang, Z., Guillaume, F., Sartelet, A., Charlier, C., Georges, M., Farnir, F., & Druet, T. (June 2012). Ancestral haplotype-based association mapping with generalized linear mixed models accounting for stratification. Bioinformatics, 28 (19), 2467-2473. doi:10.1093/bioinformatics/bts348
Peer Reviewed verified by ORBi

Van Laere, A.-S., Maglie, S., & Georges, M. (04 May 2012). Evolution of the mammalian pseudoautosomal boundary [Poster presentation]. GIGA day.

Sartelet, A., Druet, T., Michaux, C., Fasquelle, C., Geron, S., Tamma, N., Zhang, Z., Coppieters, W., Georges, M., & Charlier, C. (15 March 2012). A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response. PLoS Genetics, 15 (3), 1002581. doi:10.1371/journal.pgen.1002581
Peer Reviewed verified by ORBi

Durkin, K., Coppieters, W., Drogemuller, C., Ahariz, N., Cambisano, N., Druet, T., Fasquelle, C., Haile, A., Horin, P., Huang, L., Kamatani, Y., Karim, L., Lathrop, M., Moser, S., Oldenbroek, K., Rieder, S., Sartelet, A., Solkner, J., Stalhammar, H., ... Charlier, C. (02 February 2012). Serial translocation by means of circular intermediates underlies colour sidedness in cattle. Nature, 482 (7383), 81-4. doi:10.1038/nature10757
Peer Reviewed verified by ORBi

Charlier, C., Agerholm, J. S., Coppieters, W., Karlskov-Mortensen, P., Li, W., de Jong, G., Fasquelle, C., Karim, L., Cirera, S., Cambisano, N., Ahariz, N., Mullaart, E., Georges, M., & Fredholm, M. (2012). A deletion in the bovine FANCI gene compromises fertility by causing fetal death and brachyspina. PLoS ONE, 7 (8), 43085. doi:10.1371/journal.pone.0043085
Peer Reviewed verified by ORBi

Blard, G., Zhang, Z., Coppieters, W., & Georges, M. (2012). Identifying cows with subclinical mastitis by bulk single nucleotide polymorphism genotyping of tank milk. Journal of Dairy Science, 95 (7), 4109-13. doi:10.3168/jds.2011-5178
Peer Reviewed verified by ORBi

Sandor, C., Li, W., Coppieters, W., Druet, T., Charlier, C., & Georges, M. (2012). Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle. PLoS Genetics, 8 (7), 1002854. doi:10.1371/journal.pgen.1002854
Peer Reviewed verified by ORBi

Sartelet, A., Druet, T., Michaux, C., Fasquelle, C., Géron, S., Tamma, N., Zhang, Z., Coppieters, W., Georges, M., & Charlier, C. (09 December 2011). A splice site mutation in the bovine RNF11 gene is responsible of growth retardation and increased susceptibility to inflammatory diseases [Paper presentation]. 1st FMV Scientific Day, Liège, Belgium.

Sartelet, A., Druet, T., Zhang, Z., Michaux, C., Fasquelle, C., Géron, S., Coppieters, W., Georges, M., & Charlier, C. (10 October 2011). A splice site mutation in the bovine RNF11 gene is responsible of growth retardation and increased susceptibility to inflammatory diseases [Poster presentation]. 4th International Symposium on Animal Functional Genomics, Dublin, Ireland.

Kang, J., Kugathasan, S., Georges, M., Zhao, H., Cho, J. H., & NIDDK IBD Genetics Consortium. (15 June 2011). Improved risk prediction for Crohn's disease with a multi-locus approach. Human Molecular Genetics, 20 (12), 2435 - 2442. doi:10.1093/hmg/ddr116
Peer Reviewed verified by ORBi

Durkin, K., Cambisano, N., Ahariz, N., Fasquelle, C., Karim, L., Sartelet, A., Drogemüller, C., Leeb, T., Coppieters, W., Georges, M., & Charlier, C. (May 2011). Molecular dissection of the color-sided pehnotype in cattle reveals a novel mechanism of chromosome evolution involving circular shuttling intermediates [Poster presentation]. The Biology Of Genomes, Cold Spring Harbor, United States - New York.

Durkin, K., Cambisano, N., Ahariz, N., Fasquelle, C., Karim, L., Sartelet, A., Baurain, D., Drogemüller, C., Leeb, T., Coppieters, W., Georges, M., & Charlier, C. (May 2011). Molecular dissection of the color-sided phenotype in cattle reveals a novel mechanism of chromosome evolution involving circular shuttling intermediates. Chromosome Research, 19 (S1), 18.
Peer Reviewed verified by ORBi

Georges, M., Coppieters, W., Charlier, C., Agerholm, J. S., & Fredholm, M. (April 2011). a genetic marker test for brachyspina and fertility in cattle.

Andersson, Georges, M., Spincemaille, G., & Nezer, C. (22 February 2011). Selecting animals for parentally imprited traits.

Charlier, C., Sartelet, A., Fasquelle, C., Michaux, C., Mullaart, E., Agerholm, J. S., Fredholm, M., & Georges, M. (February 2011). Identification of disease-­causing mutations allows for unbiased estimation of their overlooked pleïotropic effects on related quantitative traits [Poster presentation]. Gordon Research Conferences on Quantitative Genetics & Genomics, Galvestone, United States - Texas.

Georges, M. (February 2011). The long and winding road from correlation to causation. Nature Genetics, 43 (3), 180-1. doi:10.1038/ng0311-180
Peer Reviewed verified by ORBi

Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D'Amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagace, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., ... Rioux, J. D. (February 2011). Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics, 43 (3), 246-52. doi:10.1038/ng.764
Peer Reviewed verified by ORBi

Merveille, A.-C., Davis, E., Becker-Heck, A., Legendre, M., Georges, M., Lequarré, A.-S., Katsanis, N., Omran, H., & Amselem, S. (2011). A bobtail ties CCDC39 to human ciliary defects and assembly of inner dynein arms and dynein regulatory complex. European Journal of Human Genetics, 19 (S2), 38.
Peer Reviewed verified by ORBi

Lequarré, A.-S., Andersson, L., Andre, C., Fredholm, M., Hitte, C., Leeb, T., Lohi, H., Lindblad-Toh, K., & Georges, M. (2011). LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs. Veterinary Journal, 189 (2), 155-9. doi:10.1016/j.tvjl.2011.06.013
Peer Reviewed verified by ORBi

Dupuis, M.-C., Zhang, Z., Druet, T., Denoix, J.-M., Charlier, C., Lekeux, P., & Georges, M. (2011). Results of a haplotype-based GWAS for recurrent laryngeal neuropathy in the horse. Mammalian Genome. doi:10.1007/s00335-011-9337-3
Peer Reviewed verified by ORBi

Merveille, A.-C.* , Davis, E. E.* , Becker-Heck, A.* , Legendre, M.* , Amirav, I., Bataille, G., Belmont, J., Beydon, N., Billen, F., Clement, A., Clercx, C., Coste, A., Crosbie, R., de Blic, J., Deleuze, S., Duquesnoy, P., Escalier, D., Escudier, E., Fliegauf, M., ... Amselem, S.*. (2011). CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs. Nature Genetics, 43 (1), 72-8. doi:10.1038/ng.726
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Momozawa, Y., Mni, M., Nakamura, K., Coppieters, W., Almer, S., Amininejad, L., Cleynen, I., Colombel, J.-F., de Rijk, P., Dewit, O., Finkel, Y., Gassull, M. A., Goossens, D., Laukens, D., Lemann, M., LIBIOULLE, C., O'Morain, C., Reenaers, C., Rutgeerts, P., ... Georges, M. (2011). Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease. Nature Genetics, 43 (1), 43-7. doi:10.1038/ng.733
Peer Reviewed verified by ORBi

Karim, L.* , Takeda, H.* , Lin, L.* , Druet, T.* , Arias, J. A. C., Baurain, D., Cambisano, N., Davis, S. R., Farnir, F., Grisart, B., Harris, B. L., Keehan, M. D., Littlejohn, M. D., Spelman, R. J., Georges, M.* , & Coppieters, W.*. (2011). Variants modulating the expression of a chromosome domain encompassing PLAG1 influence bovine stature. Nature Genetics, 43 (5), 405-13. doi:10.1038/ng.814
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Stinckens, A., Mathur, P., Janssens, S., Bruggeman, V., Onagbesan, O. M., Schroyen, M., Spincemaille, G., Decuypere, E., Georges, M., & Buys, N. (October 2010). Indirect effect of IGF2 intron3 g.3072G>A mutation on prolificacy in sows. Animal Genetics, 41 (5), 493-8. doi:10.1111/j.1365-2052.2010.02040.x
Peer Reviewed verified by ORBi

Andersson, L., Andersson, G., Georges, M., & Byus, N. (08 June 2010). Selecting animals for desired genotypic or potential phenotypic properties.

Georges, M., & Charlier, C. (19 May 2010). Method and kit for detecting genetic perdisposition for crooked tail syndrome (CTS) in bovine individuals.

Sartelet, A., Fasquelle, C., Tamma, N., Coppieters, W., Georges, M., & Charlier, C. (2010). A direct link between growth retardation and inflammation? Identification of a splice site mutation in the bovine RNF11 gene. New Biotechnology, (supplement 1), 63.

Sartelet, A., Druet, T., Coppieters, W., Georges, M., & Charlier, C. (April 2010). Towards positional identification of susceptibility loci for White Heifer disease in Belgian Blue Cattle (poster). New Biotechnology, 27 (Supplement 1), 79.

Zhang, Z., Georges, M., & Druet, T. (2010). PREDICTION OF MISSING MARKERS WITH LOW DENSITY MARKER PANELS IN DAIRY CATTLE. In Proceedings of the 9th World Congress oN Genetics Applied to Livestock Production.
Peer reviewed

Hiard, S., Charlier, C., Coppieters, W., Georges, M., & Baurain, D. (2010). Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates. Nucleic Acids Research, 38 (Database), 640-D651. doi:10.1093/nar/gkp926
Peer Reviewed verified by ORBi

Caiment, F., Charlier, C., Hadfield, T., Cockett, N., Georges, M.* , & Baurain, D.*. (2010). Assessing the effect of the CLPG mutation on the microRNA catalog of skeletal muscle using high-throughput sequencing. Genome Research, 20 (12), 1651-62. doi:10.1101/gr.108787.110
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Takeda, H., Charlier, C., Farnir, F., & Georges, M. (2010). Demonstrating polymorphic miRNA-mediated gene regulation in vivo: application to the g+6223G->A mutation of Texel sheep. RNA, 16 (9), 1854-63. doi:10.1261/rna.2131110
Peer Reviewed verified by ORBi

Druet, T., & Georges, M. (2010). A hidden markov model combining linkage and linkage disequilibrium information for haplotype reconstruction and quantitative trait locus fine mapping. Genetics, 184 (3), 789-98. doi:10.1534/genetics.109.108431
Peer Reviewed verified by ORBi

Druet, T., Zhang, Z., Coppieters, W., Mulder, H. A., Calus, M. P. L., Mullaart, E., Schrooten, C., de Roos, A. P. W., & Georges, M. (2010). Genotyping panels available in cattle and their properties. In Book of Abstracts of the 61st Annual Meeting of the European Association for Animal Production.

Franke, A., McGovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A., Bis, J. C., Bumpstead, S., Ellinghaus, D., Festen, E. M., Georges, M., Green, T., Haritunians, T., Jostins, L., ... Parkes, M. (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature Genetics, 42 (12), 1118-25. doi:10.1038/ng.717
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Georges, M., LIBIOULLE, C., & Louis, E. (2010). Dissection moléculaire de la prédisposition innée aux maladies inflamatoires chroniques de l'intestin: liason génétique, gènes candidats et études d'association du génome entier. In Maladies inflamatoires chroniques de l'instestin. Progrès en hépatho-Gastroentérologie.

Battaille, G., Lavoué, R., Peeters, D., Farnir, F., Georges, M., Charlier, C., & Lequarré, A.-S. (2010). Genetic analysis of a glomerulonephropathy segregating in a pedigree of French Mastiff. In Proceedings of 32nd Annual Conference of the International Society of Animal Genetics.
Peer reviewed

Merveille, A.-C., Davis, E., Battaille, G., Georges, M., & Lequarré, A.-S. (2010). Positional identification in the dog of a novel gene causing primary ciliary dyskinesia [Paper presentation]. Belgian Society of Human Genetics.

Laukens, D., Georges, M., Libioulle, C., Sandor, C., Mni, M., Vander Cruyssen, B., Peeters, H., Elewaut, D., & Devos, M. (2010). Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis. PLoS ONE, 5 (11), 13795. doi:10.1371/journal.pone.0013795
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Lavoué, R., van der Lugt, J. J., Day, M. J., Georges, M., Busoni, V., Merveille, A.-C., Poujade, A., & Peeters, D. (2010). Progressive juvenile glomerulonephropathy in 16 related French Mastiff (Bordeaux) Dogs. Journal of Veterinary Internal Medicine, 24 (2), 314-322. doi:10.1111/j.1939-1676.2010.0474.x
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Hiard, S., Charlier, C., Coppieters, W., Georges, M., & Baurain, D. (December 2009). Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates [Poster presentation]. BBC09, the fifth Benelux Bioinformatics Conference, Liège, Belgium.

Louis, E., Libioulle, C., Reenaers, C., Belaiche, J., & Georges, M. (October 2009). Génomique des maladies inflammatoires intestinales. Revue Médicale de Liège, 64, 24-28.
Peer reviewed

Baurain, D., Hiard, S., Coppieters, W., Charlier, C., & Georges, M. (29 September 2009). Patrocles: a database of polymorphic miR-mediated gene regulation in vertebrates [Paper presentation]. La face cachée des microRNA, Liège, Belgium.

Merveille, A.-C., Bataille, G., Davis, E., Billen, F., Clercx, C., Georges, M., & Lequarré, A.-S. (2009). Detection of a new mutation responsible for primary ciliary dyskinesia in a pedigree of old English Sheepdogs. In 19h ECVIM Meeting - Porto, Portugal - 8-10 septembre 2009.
Peer reviewed

Georges, M., Coppieters, W., Grisart, B., Snell, R., Reid, S., Ford, C., & Spelman, R. (26 May 2009). Marker assisted selection of bovine for improved milk production using diacylglycerol acyltransferase gene DGAT1.

Stinckens, A., Luyten, T., Van den Maagdenberg, K., Janssens, S., DE SMET, S., Georges, M., & Buys, N. (2009). Interactions between genes involved in growth and muscularity in pigs: IGF-2, myostatin, ryanodine receptor 1, and melanocortin-4 receptor. Domestic Animal Endocrinology, 37 (4), 227-35. doi:10.1016/j.domaniend.2009.06.002
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Koltes, J. E., Mishra, B. P., Kumar, D., Kataria, R. S., Totir, L. R., Fernando, R. L., Cobbold, R., Steffen, D., Coppieters, W., Georges, M., & Reecy, J. M. (2009). A nonsense mutation in cGMP-dependent type II protein kinase (PRKG2) causes dwarfism in American Angus cattle. Proceedings of the National Academy of Sciences of the United States of America, 106 (46), 19250-5. doi:10.1073/pnas.0904513106
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Muylkens, B., Farnir, F., Meurens, F., Schynts, F., Vanderplasschen, A., Georges, M., & Thiry, E. (2009). Co-infection with two closely related alphaherpesviruses results in a highly diversified recombination mosaic displaying negative genetic interference. Journal of Virology, 83 (7), 3127-3137. doi:10.1128/JVI.02474-08
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Imielinski, M., Baldassano, R. N., Griffiths, A., Russell, R. K., Annese, V., Dubinsky, M., Kugathasan, S., Bradfield, J. P., Walters, T. D., Sleiman, P., Kim, C. E., Muise, A., Wang, K., Glessner, J. T., Saeed, S., Zhang, H., Frackelton, E. C., Hou, C., Flory, J. H., ... Georges, M. (Other coll.). (2009). Common variants at five new loci associated with early-onset inflammatory bowel disease. Nature Genetics, 41 (12), 1335-40. doi:10.1038/ng.489
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Fasquelle, C.* , Sartelet, A.* , Li, W., Dive, M., Tamma, N., Michaux, C., Druet, T., Huijbers, I. J., Isacke, C. M., Coppieters, W., Georges, M., & Charlier, C. (2009). Balancing selection of a frame-shift mutation in the MRC2 gene accounts for the outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle. PLoS Genetics, 5 (9), 1000666. doi:10.1371/journal.pgen.1000666
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* These authors have contributed equally to this work.

Katrincsakova, B., Takeda, H., Urbankova, H., Michaux, L., Jarosova, M., Vandenberghe, P., Georges, M., Charlier, C., & Wlodarska, I. (2009). Methylation analysis of the imprinted DLK1-GTL2 domain supports the random parental origin of the IGH-involving del(14q) in B-cell malignancies. Epigenetics, 4 (7), 469-75. doi:10.4161/epi.4.7.9924
Peer reviewed

Louis, E., Libioulle, C., Reenaers, C., Belaiche, J., & Georges, M. (2009). Genetics of ulcerative colitis: the come-back of interleukin 10. Gut, 58 (9), 1173-6. doi:10.1136/gut.2008.169235
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Merveille, A.-C., Battaille, G., Billen, F., Clercx, C., Georges, M., & Lequarré, A.-S. (2009). Identification of a new mutation responsible for primary ciliary dyskinesia in dogs: a model for human PCD. Journal of Veterinary Internal Medicine.
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Coppieters, W., Mes, T. H. M., Druet, T., Farnir, F., Tamma, N., Schrooten, C., Cornelissen, A. W. C. A., Georges, M., & Ploeger, H. W. (2009). Mapping QTL influencing gastrointestinal nematode burden in Dutch Holstein-Friesian dairy cattle. BMC Genomics, 10, 96. doi:10.1186/1471-2164-10-96
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heath, S., gut, I., brennan, P., mckay, J., bencko, V., fabianova, E., foretova, L., Georges, M., janout, V., kabesch, M., krokan, H., elvestad, M., lissowska, J., mates, D., rudnai, P., skorpen, F., schreiber, S., soria, J., syvänen, A., ... Lathrop, M. (December 2008). Investigation of the fine structure of European populations with applications to disease association studies. European Journal of Human Genetics, 16, 1413-1429. doi:10.1038/ejhg.2008.210
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Blott, S., Kim, Schmidt-Kuntzel, A., Cornet, A., Berzi, P., Cambisano, N., Grisart, B., Karim, L., Simon, P., Georges, M., Farnir, F., Coppieters, W., Moisio, S., Vilkki, J., Johnson, D., Spelman, R., Ford, C., & Snell, R. (05 August 2008). Marker assisted selection of bovine for improved milk composition.

Sartelet, A., Dive, M., Touati, K., Rollin, F., Georges, M., & Charlier, C. (10 July 2008). Crooked tail and muscular hypertrophy syndrome, an emerging inherited defect in Belgian blue breed [Paper presentation]. XXVth World Buiatrics Congress, Budapest, Hungary.

Hiard, S., Baurain, D., Coppieters, W., Tordoir, X., Charlier, C., & Georges, M. (July 2008). Patrocles: a database of polymorphic miRNA-mediated gene regulation [Poster presentation]. XX International Congress of Genetics, Berlin, Germany.

Hiard, S., Baurain, D., Coppieters, W., Tordoir, X., Charlier, C., & Georges, M. (03 March 2008). Patrocles: a database of polymorphic miRNA-mediated gene regulation [Paper presentation]. EADGENE miRNAs workshop and miRNAs in Health and Disease 2 / Satellite Course "A primer in miRNA biology", Liège, Belgium.

Van Laere, A.-S., Coppieters, W., & Georges, M. (2008). Characterization of the bovine pseudoautosomal boundary: Documenting the evolutionary history of mammalian sex chromosomes. Genome Research, 18 (12), 1884-95. doi:10.1101/gr.082487.108
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Sandor, C., & Georges, M. (2008). On the detection of imprinted QTL in line crosses: effect of linkage disequilibrium. Genetics, 180, 1167-1175. doi:10.1534/genetics.108.092551
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Pirottin, D., Takeda, H., Tamma, N., Delcombel, R., Georges, M., & Charlier, C. (2008). A mouse model for polar overdominance ? In XX International Congress of Genetics.
Peer reviewed

Druet, T., Coppieters, W., Farnir, F., & Georges, M. (2008). Large-scale haplotype reconstruction using pedigree information and a Hidden Markov Model [Poster presentation]. XX International Congress of Genetics, Berlin, Germany.

Barrett, J. C., Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D., Brant, S. R., Silverberg, M. S., Taylor, K. D., Barmada, M. M., Bitton, A., Dassopoulos, T., Wu Datta, L., Green, T., Griffiths, A. M., Kistner, E. O., Murtha, M. T., Regueiro, M. D., Rotter, J. I., ... Daly, M. J. (2008). Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nature Genetics, 40 (8), 955-62. doi:10.1038/ng.175
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Charlier, C., Coppieters, W., Rollin, F., Desmecht, D., Agerholm, J. S., Cambisano, N., Carta, E., Dardano, S., Dive, M., Fasquelle, C., Frennet, J.-C., Hanset, R., Hubin, X., Jorgensen, C., Karim, L., Kent, M., Harvey, K., Pearce, B. R., Simon, P., ... Georges, M. (2008). Highly effective SNP-based association mapping and management of recessive defects in livestock. Nature Genetics, 40 (4), 449-54. doi:10.1038/ng.96
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Rollin, F., Vandeputte, S., Guyot, H., Touati, K., Desmecht, D., Charlier, C., & Georges, M. (2008). Congenital muscular dystony in the Belgian Blue breed [Paper presentation]. XXV World Buiatrics Congress, Budapest, Hungary.

Stinckens, A., Luyten, T., Bijttebier, J., Van den Maagdenberg, K., Dieltiens, D., Janssens, S., DE SMET, S., Georges, M., & Buys, N. (2008). Characterization of the complete porcine MSTN gene and expression levels in pig breeds differing in muscularity. Animal Genetics, 39 (6), 586-96. doi:10.1111/j.1365-2052.2008.01774.x
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Grobet, L., Pirottin, D., & Georges, M. (15 November 2007). Genetic engineering in the mouse: from functional genomics to zootechnical applications [Paper presentation]. BCLAS (Belgian Council for Laboratory Animal Science) symposium 2007, Geel, Belgium.

Hiard, S., Tordoir, X., Coppieters, W., Charlier, C., & Georges, M. (12 November 2007). Compiling polymorphic miRNA-target interactions: the Patrocles database [Poster presentation]. Benelux Bioinformatics Conference 2007, Leuven, Belgium.

Van den Maagdenberg, K., Stinckens, A., Claeys, E., Seynaeve, M., Clinquart, A., Georges, M., Buys, N., & De Smet, S. (September 2007). The Asp298Asn missense mutation in the porcine melanocortin-4 receptor (MC4R) gene can be used to affect growth and carcass traits without an effect on meat quality. Animal, 1 (8), 1089-1098. doi:10.1017/S1751731107000456
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Andersson, L., Georges, M., Spincemaille, G., & Nezer, C. (14 August 2007). Selecting animals for parentally imprinted traits.

Hiard, S., Tordoir, X., Coppieters, W., Charlier, C., & Georges, M. (15 February 2007). Compiling polymorphic miRNA-target interactions: the Patrocles database [Poster presentation]. Bioinformatics and Modeling : From genomes to network, Liège, Belgium.

Georges, M., & Detroz, P. (2007). Quand le testing standardisé formatif et systématique pose les jalons de l'apprentissage et offre un [Paper presentation]. CDS - IFRES, Liège, Belgium.

Georges, M., Coppieters, W., & Charlier, C. (2007). Polymorphic miRNA-mediated gene regulation: contribution to phenotypic variation and disease. Current Opinion in Genetics and Development, 17 (3), 166-76. doi:10.1016/j.gde.2007.04.005
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Stinckens, A., Van den Maagdenberg, K., Luyten, T., Georges, M., DE SMET, S., & Buys, N. (2007). The RYR1 g.1843C>T mutation is associated with the effect of the IGF2 intron3-g.3072G>A mutation on muscle hypertrophy. Animal Genetics, 38 (1), 67-71. doi:10.1111/j.1365-2052.2006.01558.x
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Georges, M. (2007). Mapping, fine mapping, and molecular dissection of quantitative trait loci in domestic animals [letter to the editor]. Annual Review of Genomics and Human Genetics, 8, 131-162. doi:10.1146/annurev.genom.8.080706.092408
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Pirottin, D., Caiment, F., Takeda, H., Tamma, N., Georges, M., & Charlier, C. (2007). A mouse model for polar overdominance ? In Workshop RiboReg, Carry le Rouet, France, 2007.
Peer reviewed

Libioulle, C., Louis, E., Hansoul, S., Sandor, C., Farnir, F., Franchimont, D., Vermeire, S., Dewit, O., de Vos, M., Dixon, A., Demarche, B., Gut, I., Heath, S., Foglio, M., Liang, L., Laukens, D., Mni, M., Zelenika, D., Van Gossum, A., ... Georges, M. (2007). Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genetics, 3 (4), 538-543. doi:10.1371/journal.pgen.0030058
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Hamelin, M., Sayd, T., Chambon, C., Bouix, J., Bibe, B., Milenkovic, D., Leveziel, H., Georges, M., Clop, A., Marinova, P., & Laville, E. (January 2007). Differential expression of sarcoplasmic proteins in four heterogeneous ovine skeletal muscles. Proteomics, 7 (2), 271-280. doi:10.1002/pmic.200600309
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Wunderlich, K. R., Abbey, C. A., Clayton, D. R., Song, Y., Schein, J. E., Georges, M., Coppieters, W., Adelson, D. L., Taylor, J. F., Davis, S. L., & Gill, C. A. (December 2006). A 2.5-Mb contig constructed from Angus, Longhorn and horned Hereford DNA spanning the polled interval on bovine chromosome 1. Animal Genetics, 37 (6), 592-594. doi:10.1111/j.1365-2052.2006.01538.x
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Vandeputte, S., Brihoum, M., Hubin, X., Georges, M., Charlier, C., Desmecht, D., Guyot, H., & Rollin, F. (15 October 2006). Congenital muscular dystonia (CMD): a new congenital pathology in Belgian Blue calves [Paper presentation]. XXIV World Buiatrics Congress, Nice, France.

Georges, M., Clop, A., Marcq, F., Takeda, H., Pirottin, D., Tordoir, X., Hiard, S., Bibé, B., Bouix, J., Caiment, F., Eychenne, F., Larzul, C., Laville, E., Meish, F., Milenkovic, D., Tobin, J., & Charlier, C. (June 2006). Polymorphic miRNA-target interactions : A Novel Source of Phenotypic Variation. Cold Spring Harbor Symposia on Quantitative Biology, 71, 343-350. doi:10.1101/sqb.2006.71.056
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Takeda, H., Caiment, F., Smit, M., Hiard, S., Tordoir, X., Cockett, N., Georges, M.* , & Charlier, C.*. (23 May 2006). The callipyge mutation enhances bidirectional long-range DLK1-GTL2 intergenic transcription in cis. Proceedings of the National Academy of Sciences of the United States of America, 103 (21), 8119-8124. doi:10.1073/pnas.0602844103
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* These authors have contributed equally to this work.

Quan, X., Laes, J.-F., Stieber, D., Rivière, M., Russo, J., Wedekind, D., Coppieters, W., Farnir, F., Georges, M., Szpirer, J., & Szpirer, C. (April 2006). Genetic identification of distinct loci controlling mammary tumor multiplicity, latency and aggressiveness in the rat. Mammalian Genome, 17 (4), 310-321. doi:10.1007/s00335-005-0125-9
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Harmegnies, N., DAVIN, F., DE SMET, S., Buys, N., Georges, M.* , & Coppieters, W.*. (2006). Results of a whole-genome quantitative trait locus scan for growth, carcass composition and meat quality in a porcine four-way cross. Animal Genetics, 37 (6), 543-53. doi:10.1111/j.1365-2052.2006.01523.x
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* These authors have contributed equally to this work.

Morreel, K., Goeminne, G., Storme, V., Sterck, L., Ralph, J., Coppieters, W., Breyne, P., Steenackers, M., Georges, M., Messens, E., & Boerjan, W. (2006). Genetical metabolomics of flavonoid biosynthesis in Populus: a case study. Plant Journal, 47 (2), 224-37. doi:10.1111/j.1365-313X.2006.02786.x
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Clop, A.* , Marcq, F.* , Takeda, H.* , Pirottin, D.* , Tordoir, X., Bibe, B., Bouix, J., Caiment, F., Elsen, J.-M., Eychenne, F., Larzul, C., Laville, E., Meish, F., Milenkovic, D., Tobin, J., Charlier, C., & Georges, M. (2006). A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nature Genetics, 38 (7), 813-8. doi:10.1038/ng1810
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* These authors have contributed equally to this work.

Hamelin, M., Sayd, T., Chambon, C., Bouix, J., Bibe, B., Milenkovic, D., Leveziel, H., Georges, M., Clop, A., Marinova, P., & Laville, E. (2006). Proteomic analysis of ovine muscle hypertrophy. Journal of Animal Science, 84 (12), 3266-76. doi:10.2527/jas.2006-162
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Viitala, S., Szyda, J., Blott, S., Schulman, N., Lidauer, M., Maki-Tanila, A., Georges, M., & Vilkki, J. (2006). The role of the bovine growth hormone receptor and prolactin receptor genes in milk, fat and protein production in Finnish Ayrshire dairy cattle. Genetics, 173 (4), 2151-64. doi:10.1534/genetics.105.046730
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Sandor, C., Farnir, F., Hansoul, S., Coppieters, W., Meuwissen, T., & Georges, M. (2006). Linkage disequilibrium on the bovine X chromosome: Characterization and use in quantitative trait locus mapping. Genetics, 173 (3), 1777-1786. doi:10.1534/genetics.106.059329
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Harmegnies, N., Farnir, F., DAVIN, F., Buys, N., Georges, M.* , & Coppieters, W.*. (2006). Measuring the extent of linkage disequilibrium in commercial pig populations. Animal Genetics, 37 (3), 225-231. doi:10.1111/j.1365-2052.2006.01438.x
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* These authors have contributed equally to this work.

Pirottin, D., Takeda, H., Georges, M., & Charlier, C. (2006). A mouse model for polar overdominance ? In Conférences Monod : Epigenetic Perspectives from Multiple Organisms.
Peer reviewed

Davis, E., Caiment, F., Tordoir, X., Cavaille, J., Ferguson-Smith, A., Cockett, N., Georges, M., & Charlier, C. (10 May 2005). Erratum to : RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus (vol 15, pg 746, 2005). Current Biology, 15 (9), 884. doi:10.1016/j.cub.2005.02.060
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Renaville, R., Georges, M., Smal, C., Gengler, N., Parmentier, I., & Portetelle, D. (2005). Contribution de la biologie moléculaire au progrès de l'élevage. In 10ème Carrefour des Productions animales: L’élevage : hier, aujourd’hui, demain quelles attentes pour quels enjeux ?
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Pirottin, D., Grobet, L., Adamantidis, A., Farnir, F., Herens, C., Daa Schroder, H., & Georges, M. (2005). Transgenic engineering of male-specific muscular hypertrophy. Proceedings of the National Academy of Sciences of the United States of America, 102 (18), 6413-8. doi:10.1073/pnas.0502426102
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Smit, M. A., Tordoir, X., Gyapay, G., Cockett, N. E., Georges, M.* , & Charlier, C.*. (2005). BEGAIN: a novel imprinted gene that generates paternally expressed transcripts in a tissue- and promoter-specific manner in sheep. Mammalian Genome, 16 (10), 801-14. doi:10.1007/s00335-004-2415-z
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* These authors have contributed equally to this work.

Pirottin, D., Grobet, L., & Georges, M. (2005). Positional cloning and genetic engineering of the myostatin gene causing double muscling in cattle. Annales de Médecine Vétérinaire, 149 (3), 135-147.
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Cockett, N. E., Smit, M. A., Bidwell, C. A., SEGERS, K., Hadfield, T. L., Snowder, G. D., Georges, M., & Charlier, C. (2005). The callipyge mutation and other genes that affect muscle hypertrophy in sheep. Genetics, Selection, Evolution, 37 Suppl 1, 65-81. doi:10.1051/gse:2004032
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Davis, E., Jensen, C., Schroder, H. D., Farnir, F., Shay-Hadfield, T., Kliem, A., Cockett, N., Georges, M.* , & Charlier, C.*. (26 October 2004). Ectopic expression of DLK1 protein in skeletal muscle of padumnal heterozygotes causes the callipyge phenotype. Current Biology, 14 (20), 1858-1862. doi:10.1016/j.cub.2004.09.079
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* These authors have contributed equally to this work.

Stockman, Y., Thizy, C., Lemaire, P., Georges, M., Mazy, E., Mazzoli, A., Houbrechts, Y., Rochus, P., Roose, S., Doyle, D., & Ulbrich, G. (2004). Development of optical ground verification method for mum to sub-mm reflectors. In 5th International Conference on Space Optics (pp. 721-727).

Werner, F. A. O., Durstewitz, G., Habermann, F. A., Thaller, G., Kramer, W., Kollers, S., Buitkamp, J., Georges, M., Brem, G., Mosner, J., & Fries, R. (February 2004). Detection and characterization of SNPs useful for identity control and parentage testing in major European dairy breeds. Animal Genetics, 35 (1), 44-49. doi:10.1046/j.1365-2052.2003.01071.x
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Andersson, L., & Georges, M. (2004). Domestic-animal genomics: deciphering the genetics of complex traits [letter to the editor]. Nature Reviews. Genetics, 5 (3), 202-212. doi:10.1038/nrg1294
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Georges, M., Charlier, C., Smit, M., Davis, E., Shay, T., Tordoir, X., Takeda, H., Caiman, F., & Cockett, N. (2004). Toward molecular understanding of polar overdominance at the ovine callipyge locus. In B. Stillman & D. Stewart (Eds.), "Epigenetics” Cold Spring Harbor Symposium on Quantitative Biology (pp. 477-483). Cold Spring Harbor Laboratory Press. doi:10.1101/sqb.2004.69.477
Peer reviewed

Grisart, B., Farnir, F., Karim, L., Cambisano, N., Kim, J.-J., Kvasz, A., Mni, M., Simon, P., Frère, J.-M., Coppieters, W., & Georges, M. (2004). Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition. Proceedings of the National Academy of Sciences of the United States of America, 101 (8), 2398-2403. doi:10.1073/pnas.0308518100
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Laville, E., Bouix, J., Sayd, T., Bibe, B., Elsen, J. M., Larzul, C., Eychenne, F., Marcq, F., & Georges, M. (2004). Effects of a quantitative trait locus for muscle hypertrophy from Belgian Texel sheep on carcass conformation and muscularity. Journal of Animal Science, 82 (11), 3128-3137. doi:10.2527/2004.82113128x
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Van Laere, A.-S.* , Nguyen, M. N.* , Braunschweig, M., Nezer, C., Collette, C., Moreau, L., Archibald, A. L., Haley, C. S., Buys, N., Tally, M., Andersson, G., Georges, M.* , & Andersson, L.*. (23 October 2003). A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig. Nature, 425 (6960), 832-836. doi:10.1038/nature02064
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* These authors have contributed equally to this work.

Smit, M.* , SEGERS, K.* , Carrascosa, L. G., Shay, T., Baraldi, F., Gyapay, G., Snowder, G., Georges, M.* , Cockett, N.* , & Charlier, C.*. (2003). Mosaicism of Solid Gold supports the causality of a noncoding A-to-G transition in the determinism of the callipyge phenotype. Genetics, 163 (1), 453-6.
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* These authors have contributed equally to this work.

Dunner, S., Miranda, M. E., Amigues, Y., Canon, J., Georges, M., Hanset, R., Williams, J., & Menissier, F. (2003). Haplotype diversity of the myostatin gene among beef cattle breeds. Genetics, Selection, Evolution, 35 (1, JAN-FEB), 103-118. doi:10.1051/gse:2002038
Peer Reviewed verified by ORBi

Georges, M., Charlier, C., & Cockett, N. (2003). The callipyge locus: evidence for the trans interaction of reciprocally imprinted genes. Trends in Genetics, 19, 248-252. doi:10.1016/S0168-9525(03)00082-9
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Nezer, C., Collette, C., Moreau, L., Brouwers, B., Kim, J. J., Giuffra, E., Buys, N., Andersson, L., & Georges, M. (2003). Haplotype sharing refines the location of an imprinted quantitative trait locus with major effect on muscle mass to a 250-kb chromosome segment containing the porcine IGF2 gene. Genetics, 165 (1), 277-285.
Peer Reviewed verified by ORBi

Blott, S., Kim, J.-J., Moisio, S., Schmidt-Kuntzel, A., Cornet, A., Berzi, P., Cambisano, N., Ford, C., Grisart, B., Johnson, D., Karim, L., Simon, P., Snell, R., Spelman, R., Wong, J., Vilkki, J., Georges, M., Farnir, F., & Coppieters, W. (2003). Molecular dissection of a quantitative trait locus: a phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition. Genetics, 163 (1), 253-66.
Peer Reviewed verified by ORBi

Grobet, L., Pirottin, D., Farnir, F., Poncelet, D., Royo, L. J., Brouwers, B., Christians, E., Desmecht, D., Coignoul, F., Kahn, R., & Georges, M. (2003). Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene. Genesis, 35 (4), 227-38. doi:10.1002/gene.10188
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Georges, M., & Andersson, L. (2003). Positional identification of structural and regulatory quantitative trait nucleotides in domestic animal species. Cold Spring Harbor Symposia on Quantitative Biology, 68, 179-87. doi:10.1101/sqb.2003.68.179
Peer Reviewed verified by ORBi

Amarger, V., Nguyen, M. N., Van Laere, A.-S., Braunschweig, M., Nezer, C., Georges, M., & Andersson, L. (July 2002). Comparative sequence analysis of the INS-IGF2-H19 gene cluster in pigs. Mammalian Genome, 13 (7), 388-398. doi:10.1007/s00335-001-3059-x
Peer Reviewed verified by ORBi

Grisart, B., Coppieters, W., Farnir, F., Karim, L., Ford, C., Berzi, P., Cambisano, N., Mni, M., Reid, S., Simon, P., Spelman, R., Georges, M., & Snell, R. (2002). Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition. Genome Research, 12 (2), 222-231. doi:10.1101/gr.224202
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Farnir, F., Grisart, B., Coppieters, W., Riquet, J., Berzi, P., Cambisano, N., Karim, L., Mni, M., Moisio, S., Simon, P., Wagenaar, D., Vilkki, J., & Georges, M. (2002). Simultaneous mining of linkage and linkage disequilibrium to fine map quantitative trait loci in outbred half-sib pedigrees: Revisiting the location of a quantitative trait locus with major effect on milk production on bovine chromosome 14. Genetics, 161 (1), 275-287.
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Kim, J. J., & Georges, M. (01 January 2002). Evaluation of a new fine-mapping method exploiting linkage disequilibrium: a case study analysing a QTL with major effect on milk composition on bovine chromosome 14. Asian-Australasian Journal of Animal Sciences, 15 (9), 1250-1256. doi:10.5713/ajas.2002.1250
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Nezer, C., Moreau, L., Wagenaar, D., & Georges, M. (2002). Results of a whole genome scan targeting QTL for growth and carcass traits in a Pietrain x Large White intercross. Genetics, Selection, Evolution, 34 (3, May-Jun), 371-387. doi:10.1051/gse:2002013
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Bidwell, C. A., Shay, T. L., Georges, M., Beever, J. E., Berghmans, S., & Cockett, N. E. (October 2001). Differential expression of the GTL2 gene within the callipyge region of ovine chromosome 18. Animal Genetics, 32 (5), 248-56. doi:10.1046/j.1365-2052.2001.00776.x
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Shay, T. L., Berghmans, S., SEGERS, K., Meyers, S., Beever, J. E., Womack, J. E., Cockett, N. E., Georges, M., & Charlier, C. (2001). Fine-mapping and construction of a bovine contig spanning the ovine callipyge locus. Mammalian Genome, 12 (2), 141-9. doi:10.1007/s003350010248
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Paulsen, M., Takada, S., Youngson, N. A., Benchaib, M., SEGERS, K., Ferguson-Smith, A. C., Georges, M., & Charlier, C. (2001). Comparative sequence analysis of the imprinted Dlk1-Gtl2 locus in three mammalian species reveals highly conserved genomic elements and refines comparison with the Igf2-H19 region. Genome Research, 11 (12), 2085-94. doi:10.1101/gr.206901
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Charlier, C., SEGERS, K., Karim, L., Shay, T., Gyapay, G., Cockett, N., & Georges, M. (2001). The callipyge (CLPG) mutation enhances the expression of the coregulated DLK1, GTL2, PEG11 and MEG8 genes in cis without affecting their imprinting status. Nature Genetics, 27, 367-369. doi:10.1038/86856
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Berghmans, S., SEGERS, K., Shay, T., Cockett, N., Georges, M., & Charlier, C. (2001). Breakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes. Mammalian Genome, 12 (2), 183-5. doi:10.1007/s003350010246
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Ikonen, T., Bovenhuis, H., Ojala, M., Uottinen, O., & Georges, M. (2001). Associations between casein haplotypes and first lactation milk production traits in Finnish Ayrshire cows. Journal of Dairy Science, 84 (2), 507-514. doi:10.3168/jds.S0022-0302(01)74501-8
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Georges, M. (2001). Recent Progress in Livestock Genomics and Potential Impact on Breeding Programs. Theriogenology, 55 (1), 15-21. doi:10.1016/S0093-691X(00)00442-8

Charlier, C., SEGERS, K., Wagenaar, D., Karim, L., Berghmans, S., Jaillon, O., Shay, T., Weissenbach, J., Cockett, N., Gyapay, G., & Georges, M. (2001). Human - ovine comparative sequencing of a 250 kilobase imprinted domain encompassing the callipyge (clpg) gene and identification of six imprinted transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11 and MEG8. Genome Research, 11, 850-862. doi:10.1101/gr.172701
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Grobet, L., & Georges, M. (15 August 2000). Double-muscling in mammals" Gene réf. Myostatin (MSTN).

Farnir, F., Coppieters, W., Arranz, J. J., Berzi, P., Cambisano, N., Grisart, B., Karim, L., Marcq, F., Moreau, L., Mni, M., Nezer, C., Simon, P., Vanmanshoven, P., Wagenaar, D., & Georges, M. (February 2000). Extensive Genome-Wide Linkage Disequilibrium in Cattle. Genome Research, 10 (2), 220-7. doi:10.1101/gr.10.2.220
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Grobet, L., Fernandez, C., Pirottin, D., Poncelet, D., Brouwers, B., & Georges, M. (2000). Engineering of the murine myostatin gene in es cells in order to generate cre-loxp-based conditional and inducible mstn on to off and mstn off to on mice strains. Cloning, 2 (3), 148.
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Marcq, F., Elsen, J.-M., Marot, V., Bouix, J., Coppieters, W., Eychenne, F., Laville, E., Nezer, C., Sayd, T., Bibe, B., Leroy, P., & Georges, M. (2000). Mapping QTL influencing muscularity in a Texel x Romanov intercross [Paper presentation]. 51st Annual Meeting of the European Association for Animal Production, Commission on Sheep and Goat Production, Paper S1.7, The Hague, The Netherlands.
Peer reviewed

Karim, L., Coppieters, W., Grobet, L., Valentini, A., & Georges, M. (2000). Convenient Genotyping of Six Myostatin Mutations Causing Double-Muscling in Cattle Using a Multiplex Oligonucleotide Ligation Assay. Animal Genetics, 31 (6), 396-9. doi:10.1046/j.1365-2052.2000.00684.x
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SEGERS, K., Vaiman, D., Berghmans, S., Shay, T., Meyers, S., Beever, J., Cockett, N., Charlier, C., & Georges, M. (2000). Construction and characterization of an ovine BAC contig spanning the callipyge locus. Animal Genetics, 31 (6), 352-9. doi:10.1046/j.1365-2052.2000.00676.x
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Georges, M. (1999). Towards Marker Assisted Selection in Livestock. Reproduction Nutrition Development, 39 (5-6, Sep-Dec), 555-61. doi:10.1051/rnd:19990504

Coppieters, W., Kvasz, A., Arranz, J. J., Grisart, B., Riquet, J., Farnir, F., & Georges, M. (1999). The great-grand-daughter design: a simple strategy to increase the power of a grand-daughter design for QTL mapping. Genetical Research, 74, 189-199. doi:10.1017/S0016672399004012
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Pirottin, D., Poncelet, D., Grobet, L., Royo, L. J., Brouwers, B., Masabanda, J., Takeda, H., Fries, R., Sugimoto, Y., Womack, J. E., Dunner, S., & Georges, M. (1999). High-Resolution, Human-Bovine Comparative Mapping Based on a Closed Yac Contig Spanning the Bovine Mh Locus. Mammalian Genome, 10 (3), 289-93. doi:10.1007/s003359900988
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Nezer, C., Moreau, L., Brouwers, B., Coppieters, W., Detilleux, J., Hanset, R., Karim, L., Kvasz, A., Leroy, P., & Georges, M. (1999). An imprinted QTL with major effect on muscle mass and fat deposition maps to the IgfII locus in pigs. Nature Genetics, 21, 155-156. doi:10.1038/5935
Peer Reviewed verified by ORBi

Riquet, J., Coppieters, W., Cambisano, N., Arranz, J. J., Berzi, P., Davis, S. K., Grisart, B., Farnir, F., Karim, L., Mni, M., Simon, P., Taylor, J. F., Vanmanshoven, P., Wagenaar, D., Womack, J. E., & Georges, M. (1999). Fine-Mapping of Quantitative Trait Loci by Identity by Descent in Outbred Populations: Application to Milk Production in Dairy Cattle. Proceedings of the National Academy of Sciences of the United States of America, 96 (16), 9252-9257. doi:10.1073/pnas.96.16.9252
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Grobet, L., Georges, M., & Poncelet, D. (01 January 1999). Mutation du Gene de la Myostatine à l'origine de l'hypertrophie muscumaire chez les mammifères.

Marcq, F., Elsen, J.-M., Marot, V., Bouix, J., Coppieters, W., Eychenne, F., Laville, E., Nezer, C., Sayd, T., Bibe, B., Georges, M., & Leroy, P. (1999). Mapping quantitative trait loci causing the muscular hypertrophy of Belgian Texel sheep [Paper presentation]. 50th Annual Meeting of the European Association for Animal Production, Zürich, Switzerland.
Peer reviewed

Coppieters, W., Mackinnon, M., & Georges, M. (1998). A note on the effect of selection on linkage analysis for quantitative traits. Journal of Heredity.
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Marcq, F., El Barkouki, S., Elsen, J.-M., Grobet, L., Royo, L., Leroy, P., & Georges, M. (1998). Investigating the role of myostatin in the determinism of double muscling characterizing Belgian Texel sheep [Paper presentation]. Proc XXVIth Int. Conf. Anim. Genet., Auckland, New Zealand (Animala Genetics, 29, suppl. 1 abstr.,52).
Peer reviewed

Mackinnon, M., & Georges, M. (1998). A bottom-up approach towards marker assisted selection. Livestock Production Science, 54, 229-250.
Peer Reviewed verified by ORBi

Georges, M. (1998). Mapping genes underlying production traits in livestock. In J. Clark, Animal Breeding: Technology for the 21st century (pp. 77-101). Harwood Academic Publishers.

Grobet, L., Poncelet, D., Royo, L. J., Brouwers, B., Pirottin, D., Geudvert, C., Menissier, F., Zanotti, M., Dunner, S., & Georges, M. (1998). Molecular Definition of an Allelic Series of Mutations Disrupting the Myostatin Function and Causing Double-Muscling in Cattle. Mammalian Genome, 9 (3), 210-3. doi:10.1007/s003359900727
Peer Reviewed verified by ORBi

Arranz, J. J., Coppieters, W., Berzi, P., Cambisano, N., Grisart, B., Karim, L., Marcq, F., Moreau, L., Mezer, C., Riquet, J., Simon, P., Vanmanshoven, P., Wagenaar, D., & Georges, M. (1998). A Qtl Affecting Milk Yield and Composition Maps to Bovine Chromosome 20: A Confirmation. Animal Genetics, 29 (2), 107-15. doi:10.1046/j.1365-2052.1998.00307.x
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Coppieters, W., Riquet, J., Arranz, J. J., Berzi, P., Cambisano, N., Grisart, B., Karim, L., Marcq, F., Moreau, L., Nezer, C., Simon, P., Vanmanshoven, P., Wagenaar, D., & Georges, M. (1998). A Qtl with Major Effect on Milk Yield and Composition Maps to Bovine Chromosome 14. Mammalian Genome, 9 (7), 540-4. doi:10.1007/s003359900815
Peer Reviewed verified by ORBi

Coppieters, W., Kvasz, A., Farnir, F., Arranz, J. J., Grisart, B., Mackinnon, M., & Georges, M. (1998). A Rank-Based Nonparametric Method for Mapping Quantitative Trait Loci in Outbred Half-Sib Pedigrees: Application to Milk Production in a Granddaughter Design. Genetics, 149 (3), 1547-55.
Peer Reviewed verified by ORBi

Georges, M. (1997). Qtl Mapping to Qtl Cloning: Mice to the Rescue. Genome Research, 7 (7), 663-665. doi:10.1101/gr.7.7.663

Georges, M. (1997). Recent progress in mammalian genomics and its implication for the selection of candidate transgenes in livestock species. In Houdebine, Transgenic animals: generation and use (pp. 519-524). Harwood Academic Publisher.

Georges, M. (1997). Case history in animal improvement: Mapping complex traits in ruminants. In A. Patterson, Molecular analysis of complex traits (pp. 229-240). CRC Press.

Dunner, S., Charlier, C., Farnir, F., Brouwers, B., Canon, J., & Georges, M. (1997). Towards interbreed IBD fine mapping of the mh locus: double-muscling in the Asturiana de los Valles breed involves the same locus as in the Belgian Blue cattle breed. Mammalian Genome, 8 (6), 430-5. doi:10.1007/s003359900462
Peer Reviewed verified by ORBi

Grobet, L., Martin, L. J., Poncelet, D., Pirottin, D., Brouwers, B., Riquet, J., Schoeberlein, A., Dunner, S., Menissier, F., Massabanda, J., Fries, R., Hanset, R., & Georges, M. (1997). A Deletion in the Bovine Myostatin Gene Causes the Double-Muscled Phenotype in Cattle. Nature Genetics, 17 (1), 71-74. doi:10.1038/ng0997-71
Peer Reviewed verified by ORBi

Charlier, C., Farnir, F., Berzi, P., Vanmanshoven, P., Brouwers, B., & Georges, M. (1996). IBD mapping of recessive traits in livestock: application to map the bovine syndactyly locus to chromosome 15. Genome Research, 6, 580-589. doi:10.1101/gr.6.7.580
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Charlier, C., Denys, B., Belanche, J. I., Coppieters, W., Grobet, L., Mni, M., Womack, J., Hanset, R., & Georges, M. (1996). Microsatellite mapping of a major determinant of White Heifer Disease: the bovine roan locus. Mammalian Genome, 7, 138-142. doi:10.1007/s003359900034
Peer Reviewed verified by ORBi

Georges, M., & Andersson, L. (1996). Livestock Genomics Comes of Age. Genome Research, 6 (10), 907-21. doi:10.1101/gr.6.10.907

Georges, M., & Cockett, N. (1996). The Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock. Reproduction Nutrition Development, 36 (6), 651-7.

Cockett, N., Jackson, S., Shaw, T., Farnir, F., Snowder, G., Nielsen, D., & Georges, M. (1996). Polar overdominance at the ovine callipyge locus. Science, 273 (5272), 236-238. doi:10.1126/science.273.5272.236
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Georges, M., Nielsen, D., Mackinnon, M., Mishra, A., Okimoto, R., Pasquino, A. T., Sargeant, L. S., Sorensen, A., Steele, M. R., Zhao, X., Womack, J. E., & Hoeschele, I. (1995). Mapping quantitative trait loci controlling milk production by exploiting progeny testing. Genetics, 139, 907-920.
Peer Reviewed verified by ORBi

Charlier, C., Coppieters, W., Farnir, F., Grobet, L., Leroy, P., Michaux, C., Mni, M., Schwers, A., Vanmanshoven, P., Hanset, R., & Georges, M. (1995). The mh gene causing double-muscling in cattle maps to bovine chromosome 2. Mammalian Genome, 6, 788-792. doi:10.1007/BF00539005
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Farnir, F., Laloux, M., Georges, M., Leroy, P., & Beduin, J.-M. (1994). Association of milk protein polymorphisms with milk production traits in two belgian dairy breeds using an animal model [Paper presentation]. 5th World Congress on Genetics Applied to Livestock Production.
Peer reviewed

Cockett, N. E., Jackson, S. P., Shay, T. D., Nielsen, D., Green, R. D., & Georges, M. (1994). Chromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers. Proceedings of the National Academy of Sciences of the United States of America, 91, 3019-3023. doi:10.1073/pnas.91.8.3019
Peer Reviewed verified by ORBi

Georges, M., Lathrop, M., Dietz, A. B., Lefort, A., Libert, F., Mishra, A., Nielsen, D., Sargeant, L. S., Steele, M. R., Zhao, X., Leipold, H., & Womack, J. E. (1993). Microsatellite mapping of the gene causing weaver disease in cattle will allow the study of an associated QTL. Proceedings of the National Academy of Sciences of the United States of America, 90, 1058-1062. doi:10.1073/pnas.90.3.1058
Peer Reviewed verified by ORBi

Delhaise, F., Zhao, X., Dessy, F., & Georges, M. (1993). Quantitative estimation of chimerism in mice using microsatellite markers. Molecular Reproduction and Development, 34 (2), 127-132. doi:10.1002/mrd.1080340203
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Libert, F., Lefort, A., Okimoto, R., & Georges, M. (1993). Construction of a bovine genomic library of large yeast artificial chromosome clones. Genomics, 18 (2), 270-276. doi:10.1006/geno.1993.1465
Peer Reviewed verified by ORBi

Georges, M., Drinkwater, R., Lefort, A., Libert, F., King, T., Mishra, A., Nielsen, D., Sargeant, L. S., Sorensen, A., Steele, M. R., Zhao, X., Womack, J. E., & Hetzel, J. (1993). Microsatellite mapping of a gene affecting horn development in Bos taurus. Nature Genetics, 4 (2), 206-210. doi:10.1038/ng0693-206
Peer Reviewed verified by ORBi

Castelli, M., Philippart, J.-C., Vassart, G., & Georges, M. (1993). Utilisation de la technique des minisatellites hypervariables chez Barbus barbus (Osteichthyes, Cyprinidae)- Poster. Cahiers d'Ethologie, 13 (2), 213-214.
Peer reviewed

Mackinnon, M. J., & Georges, M. (1992). The effects of selection on linkage analysis for quantitative traits. Genetics, 132, 1177-1185.
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Hilbert, P., Lindpaintner, K., Beckmann, J. S., Serikawa, T., Soubrier, F., Dubay, C., Cartwright, P., De Gouyon, B., Julier, C., Takahasi, S., Vincent, M., Gante, D., Georges, M., & Lathrop, G. M. (10 October 1991). Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats. Nature, 353 (6344), 521 - 529. doi:10.1038/353521a0
Peer Reviewed verified by ORBi

Steele, M., & Georges, M. (1991). Generation of bovine multisite haplotypes using random cosmids. Genomics, 10, 889-904. doi:10.1016/0888-7543(91)90177-G
Peer Reviewed verified by ORBi

Georges, M., Gunawardana, A., Threadgill, D., Lathrop, M., Olsaker, I., Mishra, A., Sargeant, L., Steele, M., Terry, C. H., Zhao, X., Holm, T., Fries, R., & Womack, J. (1991). Characterization of a set of variable number of tandem repeat markers conserved in Bovidae. Genomics, 11 (1), 24-32. doi:10.1016/0888-7543(91)90098-Y
Peer Reviewed verified by ORBi

Georges, M., & Massey, J. M. (1991). Velogenetics or the synergistic use of Marker Assisted Selection and Germ-Line Manipulation. Theriogenology, 35 (1), 151-156. doi:10.1016/0093-691X(91)90154-6
Peer Reviewed verified by ORBi

Georges, M. (1991). Hypervariable Minisatellites and their use in animal breeding. In L. B. Schook, Lewin, McLaren, ... First, Gene Mapping: strategies, techniques and applications (pp. 89-112). New York, United States: Marcel Dekker.

Georges, M. (1991). Perspectives for marker assisted selection and velogenetics in animal breeding. In Pedersen, McLaren, ... First, Animal Applications of Research in Mammalian Development (pp. 285-325). Cold Spring Harbor Laboratory Press.

Lathrop, M., Cartwright, P., Wright, S., Nakamura, K., & Georges, M. (1991). Data analysis for linkage studies. In L. B. Schook, Lewin, ... McLaren, Gene Mapping: strategies, techniques and applications (pp. 177-198). New York, United States: Marcel Dekker, New York.

Georges, M., Lathrop, M., Hilbert, P., Marcotte, A., Schwers, A., Swillens, S., Vassart, G., & Hanset, R. (1990). On the Use of DNA Fingerprints for Linkage Studies in Cattle. Genomics, 6 (3), 461-474. doi:10.1016/0888-7543(90)90476-B
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Georges, M., Lathrop, M., Bouquet, Y., Hilbert, P., Marcotte, A., Schwers, A., Roupain, J., Vassart, G., & Hanset, R. (1990). Linkage Relationships among 20 Genetic Markers in Cattle. Evidence for Linkage between Two Pairs of Blood Group Systems: B-Z and S-F/V Respectively. Animal Genetics, 21 (2), 95-105. doi:10.1111/j.1365-2052.1990.tb03213.x
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Castelli, M., Philippart, J.-C., Vassart, G., & Georges, M. (1990). DNA Fingerprinting in Fish : A new Generation of Genetic Markers. In American Fisheries Society Symposium 7 (pp. 514-520).
Peer reviewed

Perret, J., Shia, Y., Fries, R., Vassart, G., & Georges, M. (1990). A polymorphic satellite sequence maps to the pericentric region of the bovine Y chromosome. Genomics, 6 (3), 482-490. doi:10.1016/0888-7543(90)90478-D
Peer Reviewed verified by ORBi

Hilbert, P., Marcotte, F., Schwers, A., Hanset, R., Vassart, G., & Georges, M. (1989). Analysis of genetic variation in the Belgian Blue Cattle Breed using DNA sequence polymorphism at the growth hormone, low density lipoprotein receptor, -subunit of glycoprotein hormones and thyroglobulin loci. Animal Genetics, 20, 383-394. doi:10.1111/j.1365-2052.1989.tb00894.x
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Georges, M., Hilbert, P., Lequarré, A.-S., Leclercq, V., Hanset, R., & Vassart, G. (1988). Use of DNA bar codes to resolve a canine paternity dispute. Journal of the American Veterinary Medical Association, 193 (9), 1095-8.
Peer Reviewed verified by ORBi

Georges, M., Lequarré, A.-S., Castelli, M., Hanset, R., & Vassart, G. (1988). DNA fingerprinting in domestic animals using four different minisatellite probes. CytoGenetics and Cell Genetics, 47 (3), 127-31. doi:10.1159/000132529
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Vassart, G., Georges, M., Monsieur, R., Brocas, H., Lequarré, A.-S., & Christophe, D. (1987). A sequence in M13 phage detects hypervariable minisatellites in human and animal DNA. Science, 235 (4789), 683-4. doi:10.1126/science.2880398
Peer Reviewed verified by ORBi

Georges, M., Swillens, S., Bouquet, Y., Lequarré, A.-S., & Hanset, R. (1987). Genetic linkage between the bovine plasma protease inhibitor 2 (Pi-2) and S blood group loci. Animal Genetics, 18 (4), 311-6. doi:10.1111/j.1365-2052.1987.tb00774.x
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Brocas, H., Georges, M., Christophe, D., Monsieur, R., Lequarré, A.-S., & Vassart, G. (1987). Une famille de minisatellites hypervariables detectee au moyen d'une sequence derivee du phage M 13. Comptes Rendus de l'Académie des Sciences. Série III. Sciences de la Vie, 304 (3), 67-9.
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Georges, M., Lequarré, A.-S., Hanset, R., & Vassart, G. (1987). Genetic variation of the bovine thyroglobulin gene studied at the DNA level. Animal Genetics, 18 (1), 41-50. doi:10.1111/j.1365-2052.1987.tb00742.x
Peer Reviewed verified by ORBi

Georges, M., Cochaux, P., Lequarré, A.-S., Young, M. W., & Vassart, G. (1987). DNA Fingerprinting in Man Using a Mouse Probe Related to Part of the Drosophila 'Per' Gene. Nucleic Acids Research, 15 (17), 7193. doi:10.1093/nar/15.17.7193
Peer Reviewed verified by ORBi

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