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| Reference : Development of original 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as thromboxan... |
| Scientific congresses and symposiums : Poster | |||
| Human health sciences : Pharmacy, pharmacology & toxicology | |||
| http://hdl.handle.net/2268/137728 | |||
| Development of original 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as thromboxane A2 receptor antagonists | |
| English | |
Bambi Nyanguile, Sylvie-Mireille  [Université de Liège - ULiège > > > Doct. sc. bioméd. & pharma. (Bologne)] | |
| Hanson, Julien [Université de Liège - ULiège > Département de pharmacie > Chimie pharmaceutique >] | |
| Dogné, Jean-Michel [] | |
| Pirotte, Bernard [Université de Liège - ULiège > Département de pharmacie > Chimie pharmaceutique >] | |
| Aug-2012 | |
| Yes | |
| Yes | |
| International | |
| 19th EuroQSAR | |
| DU 26-30 AOUT 2012 | |
| UNIVERSITY OF VIENNA | |
| VIENNE | |
| AUTRICHE | |
| [en] Thromboxane receptor antagonists ; antiplatelet agents ; 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas | |
| [en] A series of novel 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas were synthesized.
The newly synthesized compounds were tested in vitro and ex vivo as thromboxane A2 receptor antagonists. Some of the test compounds showed potent thromboxane A2 receptor antagonist activity. Three compounds (7h, 8h and 8e) were identified as leads for further pharmacological and toxicological studies. | |
| LABORATOIRE DE CHIMIE PHARMACEUTIQUE | |
| COOPERATION TECHNIQUE BELGIQUE | |
| DEVELOPPEMENT DE NOUVELLES BENZENES SULFONYLUREES DIVERSEMENTS SUBSTITUEES EN TANT QU ANTAGONISTES DES RECEPTEURS AU THROMBOXANE A2 | |
| Researchers ; Professionals ; Students ; General public | |
| http://hdl.handle.net/2268/137728 |
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