Evaluation of Autoantibodies against Oxidized Ldl and Antioxidant Status in Top Soccer and Basketball Players after 4 Months of Competition

Pincemail, Joël; Lecomte, J.; Castiau, J.; Collard, E.; Vasankari, T.; Cheramy-Bien, Jean-Paul; Limet, Raymond; Defraigne, Jean-Olivier

doi:10.1016/S0891-5849(99)00259-2

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Evaluation of Autoantibodies against Oxidized Ldl and Antioxidant Status in Top Soccer and Basketball Players after 4 Months of Competition

Pincemail, Joël; Lecomte, J.; Castiau, J. et al.

2000 • In Free Radical Biology and Medicine, 28 (4), p. 559-65

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https://hdl.handle.net/2268/112536

DOI
10.1016/S0891-5849(99)00259-2

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10719237

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Abstract :

[en] Antioxidant status and titers of autoantibodies against oxidized low-density lipoproteins (ox-LDL-Ab) were investigated in top soccer (S; n = 21, age 24.6 +/- 4.3 years) and basketball (B; n 3,000 mIU/ml) in ox-LDL-Ab were found in half the players (12S and 4B) with a maximum reaching 6000 mIU/ml (normal range: 200-600 mIU/ml), showing an in vivo LDL oxidation. There was no correlation between ox-LDL-Ab titers and chlolesterol, LDL cholesterol, or antioxidant levels. Nevertheless, plasma vitamin C concentration was lower in athletes having high levels of ox-LDL-Ab when compared with those with normal levels (8.49 +/- 3.14 mirogram/ml vs. 10.39 +/- 2.55 microgram/ml), but this difference was not statistically significant. In conclusion, our data suggest that potential atherogenic and cardiovascular risks as reflected by high titers in ox-LDL-Ab may exist in some top athletes despite a nonaltered antioxidant status.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Pincemail, Joël ; Centre Hospitalier Universitaire de Liège - CHU > Chirurgie cardio-vasculaire

Lecomte, J.

Castiau, J.

Collard, E.

Vasankari, T.

Cheramy-Bien, Jean-Paul ; Centre Hospitalier Universitaire de Liège - CHU > Chirurgie cardio-vasculaire

Limet, Raymond ; Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique

Defraigne, Jean-Olivier ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie générale, bioch. et path. humaine et pathologiques

Language :

English

Title :

Evaluation of Autoantibodies against Oxidized Ldl and Antioxidant Status in Top Soccer and Basketball Players after 4 Months of Competition

Publication date :

10 February 2000

Journal title :

Free Radical Biology and Medicine

ISSN :

0891-5849

eISSN :

1873-4596

Publisher :

Elsevier, Amsterdam, Netherlands

Volume :

Issue :

Pages :

559-65

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 22 February 2012

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