Article (Scientific journals)
Circadian preference modulates the neural substrate of conflict processing across the day
Schmidt, Christina; Peigneux, Philippe; Leclercq, Yves et al.
2012In PLoS ONE, 7 (1), p. 29658
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Keywords :
ciracadian; inhibition
Abstract :
[en] Human morning and evening chronotypes differ in their preferred timing for sleep and wakefulness, as well as in optimal daytime periods to cope with cognitive challenges. Recent evidence suggests that these preferences are not a simple by-product of socio-professional timing constraints, but can be driven by inter-individual differences in the expression of circadian and homeostatic sleep-wake promoting signals. Chronotypes thus constitute a unique tool to access the interplay between those processes under normally entrained day-night conditions, and to investigate how they impinge onto higher cognitive control processes. Using functional magnetic resonance imaging (fMRI), we assessed the influence of chronotype and time-of-day on conflict processing-related cerebral activity throughout a normal waking day. Sixteen morning and 15 evening types were recorded at two individually adapted time points (1.5 versus 10.5 hours spent awake) while performing the Stroop paradigm. Results show that interference-related hemodynamic responses are maintained or even increased in evening types from the subjective morning to the subjective evening in a set of brain areas playing a pivotal role in successful inhibitory functioning, whereas they decreased in morning types under the same conditions. Furthermore, during the evening hours, activity in a posterior hypothalamic region putatively involved in sleep-wake regulation correlated in a chronotype-specific manner with slow wave activity at the beginning of the night, an index of accumulated homeostatic sleep pressure. These results shed light into the cerebral mechanisms underlying inter-individual differences of higher-order cognitive state maintenance under normally entrained day-night conditions.
Disciplines :
Neurosciences & behavior
Psychiatry
Author, co-author :
Schmidt, Christina  
Peigneux, Philippe ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Leclercq, Yves 
Sterpenich, Virginie 
Vandewalle, Gilles  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Phillips, Christophe  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Berthomier, Pierre
Berthomier, Christian
Tinguely, Gilberte
Gais, Steffen
Schabus, Manuel
Desseilles, Martin ;  Université de Liège > Centre de recherches du cyclotron
Dang Vu, Thien Thanh ;  Université de Liège - ULiège > Département des sciences cliniques > Neurologie
Salmon, Eric  ;  Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.
Degueldre, Christian ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Balteau, Evelyne ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Luxen, André ;  Université de Liège - ULiège > Département de chimie (sciences) > Chimie organique de synthèse
Cajochen, Christian
Maquet, Pierre  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Collette, Fabienne  ;  Université de Liège - ULiège > Département de Psychologie : cognition et comportement > Neuropsychologie
More authors (10 more) Less
Language :
English
Title :
Circadian preference modulates the neural substrate of conflict processing across the day
Publication date :
2012
Journal title :
PLoS ONE
eISSN :
1932-6203
Publisher :
Public Library of Science, San Franscisco, United States - California
Volume :
7
Issue :
1
Pages :
e29658
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
Available on ORBi :
since 20 January 2012

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