Profil

Maia Ladeira Luiz Carlos

GIGA Mol. Comput. Bio. - Biomecha. & Comput. Tissues Engin.

Département d'aérospatiale et mécanique > Génie biomécanique

See author's contact details
ORCID
0000-0002-7152-2688
Main Referenced Co-authors
Geris, Liesbet  (30)
Staumont, Bernard  (30)
Gamba, Alessio  (26)
Vanhaecke, Tamara (10)
Jover, Ramiro (9)
Main Referenced Keywords
Toxicology (7); toxicology (6); General Medicine (3); Adverse outcome pathway (2); Animals (2);
Main Referenced Disciplines
Life sciences: Multidisciplinary, general & others (16)
Biochemistry, biophysics & molecular biology (13)
Human health sciences: Multidisciplinary, general & others (12)
Engineering, computing & technology: Multidisciplinary, general & others (2)
Endocrinology, metabolism & nutrition (1)

Publications (total 45)

The most downloaded
291 downloads
MARRIEL, N. B., Maia Ladeira, L. C., ARAÚJO, R. D. S., da SILVA, J., MARTINS, A. L. P., & TAVARES, M. G. (08 June 2021). Playfulness in the Teaching of Cell Biology: possibilities in higher education. Elo, 10, 1–11. doi:10.21284/elo.v10i.12290 https://hdl.handle.net/2268/297626

The most cited

16 citations (OpenAlex)

de Paula Dias Moreira, L., Enes, B. R. N., de São José, V. C. P. B., Toledo, R. C. L., Maia Ladeira, L. C., Cardoso, R. R., da Silva Duarte, V. C., Hermsdorff, H. H. M., de Barros, F. A. R., & Martino, H. R. S. D. (21 January 2022). Chia (Salvia hispanica L.) Flour and Oil Ameliorate Metabolic Disorders in the Liver of Rats Fed a High-Fat and High Fructose Diet. Foods, 11 (3), 285. doi:10.3390/foods11030285 https://hdl.handle.net/2268/297620

Articles accepted in reviewed journal

dos Prazeres, J. L., Almeida, A. A., Carvalho, R. P. R., Maia Ladeira, L. C., de Souza Costa, L. P., Kohlhoff, M., de Oliveira, L. L., Machado-Neves, M., & Leite, J. P. V. (2025). Exploring the safety parameters of Athenaea velutina ethanolic extract: a step towards harnessing its medicinal potential. Toxicological Research. doi:10.1007/s43188-024-00276-7
Peer reviewed

Staumont, B., Maia Ladeira, L. C., Gamba, A., Heusinkveld, H. J., Piersma, A., Fritsche, E., Masereeuw, R., Vanhaecke, T., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vinken, M., & Geris, L. (2025). Mapping physiology: a systems biology approach for the development of alternative methods in toxicology. ALTEX: Alternatives to Animal Experimentation. doi:10.5281/zenodo.14278276
Editorial reviewed

Niarakis, A., Laubenbacher, R., An, G., Ilan, Y., Fisher, J., Flobak, Å., Reiche, K., Rodríguez Martínez, M., Geris, L., Maia Ladeira, L. C., Veschini, L., Blinov, M. L., Messina, F., Fonseca, L. L., Ferreira, S., Montagud, A., Noël, V., Marku, M., Tsirvouli, E., ... Glazier, J. A. (30 November 2024). Immune digital twins for complex human pathologies: applications, limitations, and challenges. NPJ Systems Biology and Applications, 10 (1), 141. doi:10.1038/s41540-024-00450-5
Peer Reviewed verified by ORBi

Santana, F. D. F. V., Da Silva, J., Lozi, A. A., Araujo, D. C., Maia Ladeira, L. C., De Oliveira, L. L., & Da Matta, S. L. P. (December 2023). Toxicology of arsenate, arsenite, cadmium, lead, chromium, and nickel in testes of adult Swiss mice after chronic exposure by intraperitoneal route. Journal of Trace Elements in Medicine and Biology, 80, 127271. doi:10.1016/j.jtemb.2023.127271
Peer Reviewed verified by ORBi

Dias, F. C. R., Cupertino, M. C., Silva, P. G., Oliveira, E. L., Maia Ladeira, L. C., Matta, S. L. P., Otoni, W. C., & Gomes, M. L. M. (2023). Exposure to Pfaffia glomerata causes oxidative stress and triggers hepatic changes. Brazilian Journal of Biology, 83, 271425. doi:10.1590/1519-6984.271425
Peer reviewed

de Paula Dias Moreira, L., Enes, B. R. N., de São José, V. C. P. B., Toledo, R. C. L., Maia Ladeira, L. C., Cardoso, R. R., da Silva Duarte, V. C., Hermsdorff, H. H. M., de Barros, F. A. R., & Martino, H. R. S. D. (21 January 2022). Chia (Salvia hispanica L.) Flour and Oil Ameliorate Metabolic Disorders in the Liver of Rats Fed a High-Fat and High Fructose Diet. Foods, 11 (3), 285. doi:10.3390/foods11030285
Peer Reviewed verified by ORBi

Castro, T. L. P. A. E., Maia Ladeira, L. C., Santos, C. F. F., de Deus, F. A. N., Gomes, A. R., Bastos, D. S. S., Souza, A. C. U. F., & dos Santos, E. R. C. (27 July 2021). Chronic caffeine use does not influence behavior and brain oxidative status in mice. Revista da Associação Brasileira de Nutrição, 12 (2), 146–166. doi:10.47320/rasbran.2021.2014
Peer reviewed

de Souza, F. B., Novaes, R. M. D., Santos, C. F. F., de Deus, F. A., Santos, F. C., Maia Ladeira, L. C., Gonçalves, R. V., Bastos, D. S. S., Souza, A. C. U. F., Machado-Neves, M., & dos Santos, E. R. C. (01 July 2021). High-fat diet and caffeine interact to modulate bone microstructure and biomechanics in mice. Life Sciences, 276 (March), 119450. doi:10.1016/j.lfs.2021.119450
Peer Reviewed verified by ORBi

Guimarães-Ervilha, L. O. V., Maia Ladeira, L. C., Carvalho, R. P. R., Bento, I. P. D. S., Bastos, D. S. S., Souza, A. C. U. F., Santos, E. R. C., de Oliveira, L. L., Maldonado, I. R. D. S. C., & Machado-Neves, M. (29 June 2021). Green Tea Infusion Ameliorates Histological Damages in Testis and Epididymis of Diabetic Rats. Microscopy and Microanalysis, 27 (5), 1133–1145. doi:10.1017/S1431927621012071
Peer Reviewed verified by ORBi

Maia Ladeira, L. C., dos Santos, E. R. C., Santos, T. A., da Silva, J., Lima, G. D. D. A., Machado-Neves, M., da Silva, R. C., Freitas, M. B., & Maldonado, I. R. D. S. C. (28 June 2021). Green tea infusion prevents diabetic nephropathy aggravation in recent-onset type 1 diabetes regardless of glycemic control. Journal of Ethnopharmacology, 274 (January), 114032. doi:10.1016/j.jep.2021.114032
Peer Reviewed verified by ORBi

MARRIEL, N. B., Maia Ladeira, L. C., ARAÚJO, R. D. S., da SILVA, J., MARTINS, A. L. P., & TAVARES, M. G. (08 June 2021). Playfulness in the Teaching of Cell Biology: possibilities in higher education. Elo, 10, 1–11. doi:10.21284/elo.v10i.12290
Peer Reviewed verified by ORBi

Mishima, M. D. V., Maia Ladeira, L. C., da Silva, B. R. P., Toledo, R. C. L., de Oliveira, T. S. V., Costa, N. M. B., & Martino, H. R. S. D. (15 February 2021). Cardioprotective action of chia ( Salvia hispanica L.) in ovariectomized rats fed a high fat diet. Food and Function, 12 (7), 3069–3082. doi:10.1039/D0FO03206A
Peer Reviewed verified by ORBi

Mouro, V. G. S., Maia Ladeira, L. C., Lozi, A. A., de Medeiros, T. S., Silva, M. R., de Oliveira, E. L., de Melo, F. C. S. A., & da Matta, S. R. L. P. (05 January 2021). Different Routes of Administration Lead to Different Oxidative Damage and Tissue Disorganization Levels on the Subacute Cadmium Toxicity in the Liver. Biological Trace Element Research, 199 (12), 4624–4634. doi:10.1007/s12011-020-02570-5
Peer Reviewed verified by ORBi

Maia Ladeira, L. C., dos Santos, E. R. C., Valente, G. E., da Silva, J., Santos, T. A., & dos Santos Costa Maldonado, I. R. (25 October 2019). Could biological tissue preservation methods change chemical elements proportion measured by energy dispersive X-ray spectroscopy? Biological Trace Element Research, 196 (1), 168–172. doi:10.1007/s12011-019-01909-x
Peer Reviewed verified by ORBi

Articles accepted in conference proceedings

Gamba, A., Maia Ladeira, L. C., Barnes, D. A., Janssen, M. J., Masereeuw, R., Geris, L., & Staumont, B. (September 2024). P05-50 Using ontology map and physiological map to improve predictive models for kidney toxicity. Toxicology Letters, 399, 151-S152. doi:10.1016/j.toxlet.2024.07.385
Peer Reviewed verified by ORBi

Maia Ladeira, L. C., Mazein, A., Ostaszewski, M., Verhoeven, A., Kuchovská, E., Sanz-Serrano, J., Drees, A., Reiche, K., Sewald, K., Fritsche, E., Vinken, M., Geris, L., & Staumont, B. (September 2024). OS02-03 Using a systems biology approach to construct adverse outcome pathway networks aligned with the FAIR principles. Toxicology Letters, 399, 58. doi:10.1016/j.toxlet.2024.07.164
Peer Reviewed verified by ORBi

Kuchovska, E., Maia Ladeira, L. C., Bartmann, K., Polozij, D., Gorts, N., Corek, E., Donmez, A., Saborowski, L.-C., Bendt, F., Schade, M., Raad, G., Gamba, A., Staumont, B., Bal-Price, A., Wojewodzic, M., Lislien, M., Impelizzeri, A., Hofer, T., Dirven, H., ... Fritsche, E. (September 2024). S05-01 Functional mapping of neurodevelopmental disorders to ontology-based DNT NAMs for Next Generation Risk Assessment of chemicals. Toxicology Letters, 399, 18. doi:10.1016/j.toxlet.2024.07.056
Peer Reviewed verified by ORBi

Kuchovska, E., Maia Ladeira, L. C., Hayot, G., Martinez, R., Islam, B., Veltman, K., Zajac, J. D., Ormanin-Lewandowska, A., Mone, M., Kandarova, H., Tangianu, S., Palloca, G., & Busquet, F. (September 2024). P02-04 ASPIS Academy: empowering the next generation of toxicologists. Toxicology Letters, 399, 105. doi:10.1016/j.toxlet.2024.07.274
Peer Reviewed verified by ORBi

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Serrano, J. S., Kuchovska, E., Berkhout, J., A., D., Teunis, M., Luechtefeld, T. H., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (September 2024). P05-45 Ontology maps: data integration tools for applications in toxicology. Toxicology Letters, 399, 149-S150. doi:10.1016/j.toxlet.2024.07.380
Peer Reviewed verified by ORBi

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Janssen, M. J., Teunis, M., Luechtefeld, T. H., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). Mapping Physiology As A Basis For Building Disease Ontology Maps. In 22ND INTERNATIONAL CONGRESS ESTIV BOOK OF ABSTRACTS. ESTIV.
Peer reviewed

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). From physiological maps to disease ontology maps using a systems biology approach. In Book of Abstracts. 3rd Annual Meeting of the ONTOX Project. ZENODO.
Peer reviewed

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). Building disease ontology maps: in silico tools for applications in toxicology. In VPH Conference 2024 Book of Abstracts. VPH2024.
Peer reviewed

Berkhout, J. H., Piersma, A., Legler, J., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R., Geris, L., Knudsen, T. B., Spencer, R. M., & Heusinkveld, H. J. (September 2023). P06-05: Towards a virtual embryo: Computational modelling of neural tube closure defects. Toxicology Letters, 384, 106. doi:10.1016/s0378-4274(23)00510-6
Peer Reviewed verified by ORBi

Gamba, A., Maia Ladeira, L. C., Lesage, R., Barnes, D. A., Janssen, M. J., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (September 2023). P06-36: The nephron physiological map as a tool to build kidney disease ontologies. Toxicology Letters, 384, 119. doi:10.1016/s0378-4274(23)00539-8
Peer Reviewed verified by ORBi

Maia Ladeira, L. C., Kuchovská, E., Görts, N., Hofer, T., Myhre, O., Lopez Soop, G. L. S., Dirven, H., Gamba, A., Lesage, R., Fritsche, E., Geris, L., & Staumont, B. (September 2023). LP-24: The Cognitive Function Defects Ontology: Integrating Biological, Toxicological, and Chemical Data for Next-Generation Risk Assessment. Toxicology Letters, 384, 316-S317. doi:10.1016/s0378-4274(23)00989-x
Peer Reviewed verified by ORBi

Kuchovska, E., Bartmann, K., Maia Ladeira, L. C., Dönmez, A., Saborowski, L.-C., Bendt, F., Schade, M., Raad, G., Lesage, R., Gamba, A., Staumont, B., Geris, L., & Fritsche, E. (September 2023). P22-35: Mapping of DNT NAMs’ signaling pathways in human physiology and disease for regulatory application. Toxicology Letters, 384, 264. doi:10.1016/s0378-4274(23)00868-8
Peer Reviewed verified by ORBi

Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., van Ertvelde, J., Jiang, J., Roodzant, D. L., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Heuseinkveld, H., Geris, L., & Staumont, B. (2022). Designing physiological maps as a tool to study liver toxicology. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.
Editorial reviewed

Barnes, D., Irvine, A., Gamba, A., Maia Ladeira, L. C., Staumont, B., Yang, H., Steffensen, I.-L., Geris, L., Janssen, M., & Masereeuw, R. (2022). Development of an adverse outcome pathway for kidney tubular necrosis. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.
Editorial reviewed

Berkhout, J., Piersma, A., Legler, J., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Geris, L., & Heuseinkveld, H. (2022). Computational modelling of neural tube closure defects. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.
Editorial reviewed

Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., Jiang, J., van Ertvelde, J., Jover, R., Vanhaecke, T., Mathieu, V., Geris, L., & Staumont, B. (2022). Developing a physiological map as a framework to study chemical- induced liver steatosis. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi.
Editorial reviewed

Gamba, A., Maia Ladeira, L. C., Lesage, R. L., Roodzant, D. L., Barnes, D. A., Janssen, M. J., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (2022). From Physiological Map to Ontology Unravelling Kidney Toxicity From Physiological Map to Ontology Unravelling Kidney Toxicity. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi.
Editorial reviewed

Maia Ladeira, L. C., Gamba, A., Lesage, R., Ertvelde, J. V., Jiang, J., Verhoeven, A., Roodzant, D., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Geris, L., & Staumont, B. (September 2022). P11-09 Physiology-based framework to study chemical-induced cholestasis. Toxicology Letters, 368, 165-S166. doi:10.1016/j.toxlet.2022.07.459
Peer Reviewed verified by ORBi

Kuchovska, E., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R., Steffensen, I.-L., Soop, G. L., Hofer, T., Myhre, O., Dirven, H., Geris, L., & Fritsche, E. (September 2022). SOC-II-09 First steps for creating an ontology for cognitive function defects for regulatory application. Toxicology Letters, 368, 35-S36. doi:10.1016/j.toxlet.2022.07.112
Peer Reviewed verified by ORBi

Staumont, B., Maia Ladeira, L. C., Gamba, A., Lesage, R., Verhoeven, A., Jiang, J., Ertvelde, J. V., Barnes, D. A., Janssen, M. J., Kuchovska, E., Berkhout, J., Roodzant, D., Teunis, M., Bozada, T., Luechtefeld, T. H., Jover, R., Vanhaecke, T., Vinken, M., Masereeuw, R., ... Geris, L. (September 2022). SOC-VI-08 Physiological maps: a benchmark tool for adverse outcome pathways and a cornerstone for the development of disease ontologies. Toxicology Letters, 368, 77-S78. doi:10.1016/j.toxlet.2022.07.228
Peer Reviewed verified by ORBi

Barnes, D., Irvine, A., Gamba, A., Staumont, B., Maia Ladeira, L. C., Yang, H., Steffensen, I.-L., Geris, L., Janssen, M., & Masereeuw, R. (September 2022). P01-07 Development of an adverse outcome pathway for kidney tubular necrosis. Toxicology Letters, 368, 86-S87. doi:10.1016/j.toxlet.2022.07.251
Peer Reviewed verified by ORBi

Gamba, A., Maia Ladeira, L. C., Lesage, R., Barnes, D. A., Roodzant, D., Teunis, M., Janssen, M. J., Masereeuw, R., Geris, L., & Staumont, B. (2022). P04-06 New approaches for evaluating kidney toxicity using physiological maps. Toxicology Letters. doi:10.1016/j.toxlet.2022.07.290
Peer Reviewed verified by ORBi

Oral presentations in conferences with scientific selection committee

Maia Ladeira, L. C., Mazein, A., Ostaszewski, M., Verhoeven, A., Sanz-Serrano, J., Drees, A. H., Vanhaecke, T., Vinken, M., Geris, L., & Staumont, B. (March 2024). Semi-automated workflow to accelerate AOP network construction using SBGN elements: a pilot study [Paper presentation]. 8th Disease Maps Community Meeting.
Peer reviewed

Posters presentations in conferences with scientific selection committee

Kuchovska, E., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Steffensen, I.-L., Soop, G. L., Hofer, T., Myhre, O., Dirven, H., Geris, L., & Fritsche, E. (24 November 2022). FIRST STEPS FOR CREATING AN ONTOLOGY FOR COGNITIVE FUNCTION DEFECTS FOR REGULATORY APPLICATION [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain.
Editorial reviewed

Maia Ladeira, L. C.* , Gamba, A.* , Lesage, R., Kuchovska, E., Görts, N., Verhoeven, A., Jiang, J., van Ertvelde, J., Barnes, D., Janssen, M., Berkhout, J., Roodzant, D., Teunis, M., Bozada, T. J., Luechtefeld, T., Jover, R., Vanhaecke, T., Vinken, M., Masereeuw, R., ... Staumont, B. (24 November 2022). Physiological maps and chemical-induced disease ontologies: tools to support NAMs development for next-generation risk assessment [Poster presentation]. ASPIS Open Symposium, Sitges, Spain.
Editorial reviewed
* These authors have contributed equally to this work.

Gamba, A., Maia Ladeira, L. C., Lesage, R., Roodzant, D., Barnes, D., Janssen, M., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (20 October 2022). Physiological map to study kidney toxicity in the ONTOX project [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain.
Editorial reviewed

Preprints

Messina, F., Rotondo, C., Maia Ladeira, L. C., Properzi, M., Dimartino, V., Riccitelli, B., Staumont, B., Chilemi, G., Geris, L., Bocci, M. G., & Fontana, C. (2024). Building a model of sepsis: data integration unravels pathogenic mechanisms in severe P. aeruginosa infections. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/327015. doi:10.1101/2024.10.17.618881

Maia Ladeira, L. C., dos Santos, E. C., Mendes, B. F., Gutierrez, E. A., Santos, C. F. F., de Souza, F. B., Machado-Neves, M., & Maldonado, I. R. D. S. C. (2020). Green tea infusion aggravates nutritional status of the juvenile untreated STZ-induced type 1 diabetic rat. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/327031. doi:10.1101/2020.01.13.904896

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