![]() ![]() | Staumont, B., Maia Ladeira, L. C., Gamba, A., Heusinkveld, H. J., Piersma, A., Fritsche, E., Masereeuw, R., Vanhaecke, T., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vinken, M., & Geris, L. (2025). Mapping physiology: a systems biology approach for the development of alternative methods in toxicology. ALTEX: Alternatives to Animal Experimentation. doi:10.5281/zenodo.14278276 ![]() |
![]() ![]() | Maia Ladeira, L. C., Verhoeven, A., van Ertvelde, J., Jiang, J., Gamba, A., Sanz Serrano, J., Vanhaecke, T., Heusinkveld, H. J., Jover, R., Vinken, M., Geris, L., & Staumont, B. (2024). Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/327181. doi:10.5281/zenodo.14515238 |
![]() ![]() | Maia Ladeira, L. C., Staumont, B., Gamba, A., & Geris, L. (2024). ONTOX's Physiological Maps Curation Guidelines. doi:10.5281/zenodo.13239453 |
![]() ![]() | Gamba, A., Maia Ladeira, L. C., Barnes, D. A., Janssen, M. J., Masereeuw, R., Geris, L., & Staumont, B. (September 2024). P05-50 Using ontology map and physiological map to improve predictive models for kidney toxicity. Toxicology Letters, 399, 151-S152. doi:10.1016/j.toxlet.2024.07.385 ![]() |
![]() ![]() | Kuchovska, E., Maia Ladeira, L. C., Bartmann, K., Polozij, D., Gorts, N., Corek, E., Donmez, A., Saborowski, L.-C., Bendt, F., Schade, M., Raad, G., Gamba, A., Staumont, B., Bal-Price, A., Wojewodzic, M., Lislien, M., Impelizzeri, A., Hofer, T., Dirven, H., ... Fritsche, E. (September 2024). S05-01 Functional mapping of neurodevelopmental disorders to ontology-based DNT NAMs for Next Generation Risk Assessment of chemicals. Toxicology Letters, 399, 18. doi:10.1016/j.toxlet.2024.07.056 ![]() |
![]() ![]() | Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Serrano, J. S., Kuchovska, E., Berkhout, J., A., D., Teunis, M., Luechtefeld, T. H., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (September 2024). P05-45 Ontology maps: data integration tools for applications in toxicology. Toxicology Letters, 399, 149-S150. doi:10.1016/j.toxlet.2024.07.380 ![]() |
Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Janssen, M. J., Teunis, M., Luechtefeld, T. H., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). Mapping Physiology As A Basis For Building Disease Ontology Maps. In 22ND INTERNATIONAL CONGRESS ESTIV BOOK OF ABSTRACTS. ESTIV. ![]() |
Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). From physiological maps to disease ontology maps using a systems biology approach. In Book of Abstracts. 3rd Annual Meeting of the ONTOX Project. ZENODO. ![]() |
Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). Building disease ontology maps: in silico tools for applications in toxicology. In VPH Conference 2024 Book of Abstracts. VPH2024. ![]() |
![]() ![]() | Berkhout, J. H., Piersma, A., Legler, J., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R., Geris, L., Knudsen, T. B., Spencer, R. M., & Heusinkveld, H. J. (September 2023). P06-05: Towards a virtual embryo: Computational modelling of neural tube closure defects. Toxicology Letters, 384, 106. doi:10.1016/s0378-4274(23)00510-6 ![]() |
![]() ![]() | Gamba, A., Maia Ladeira, L. C., Lesage, R., Barnes, D. A., Janssen, M. J., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (September 2023). P06-36: The nephron physiological map as a tool to build kidney disease ontologies. Toxicology Letters, 384, 119. doi:10.1016/s0378-4274(23)00539-8 ![]() |
![]() ![]() | Maia Ladeira, L. C., Kuchovská, E., Görts, N., Hofer, T., Myhre, O., Lopez Soop, G. L. S., Dirven, H., Gamba, A., Lesage, R., Fritsche, E., Geris, L., & Staumont, B. (September 2023). LP-24: The Cognitive Function Defects Ontology: Integrating Biological, Toxicological, and Chemical Data for Next-Generation Risk Assessment. Toxicology Letters, 384, 316-S317. doi:10.1016/s0378-4274(23)00989-x ![]() |
![]() ![]() | Kuchovska, E., Bartmann, K., Maia Ladeira, L. C., Dönmez, A., Saborowski, L.-C., Bendt, F., Schade, M., Raad, G., Lesage, R., Gamba, A., Staumont, B., Geris, L., & Fritsche, E. (September 2023). P22-35: Mapping of DNT NAMs’ signaling pathways in human physiology and disease for regulatory application. Toxicology Letters, 384, 264. doi:10.1016/s0378-4274(23)00868-8 ![]() |
![]() ![]() | Kuchovska, E., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Steffensen, I.-L., Soop, G. L., Hofer, T., Myhre, O., Dirven, H., Geris, L., & Fritsche, E. (24 November 2022). FIRST STEPS FOR CREATING AN ONTOLOGY FOR COGNITIVE FUNCTION DEFECTS FOR REGULATORY APPLICATION [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain. ![]() |
![]() ![]() | Maia Ladeira, L. C.* , Gamba, A.* , Lesage, R., Kuchovska, E., Görts, N., Verhoeven, A., Jiang, J., van Ertvelde, J., Barnes, D., Janssen, M., Berkhout, J., Roodzant, D., Teunis, M., Bozada, T. J., Luechtefeld, T., Jover, R., Vanhaecke, T., Vinken, M., Masereeuw, R., ... Staumont, B. (24 November 2022). Physiological maps and chemical-induced disease ontologies: tools to support NAMs development for next-generation risk assessment [Poster presentation]. ASPIS Open Symposium, Sitges, Spain. ![]() * These authors have contributed equally to this work. |
![]() ![]() | Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., van Ertvelde, J., Jiang, J., Roodzant, D. L., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Heuseinkveld, H., Geris, L., & Staumont, B. (2022). Designing physiological maps as a tool to study liver toxicology. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV. ![]() |
![]() ![]() | Gamba, A., Maia Ladeira, L. C., Lesage, R., Roodzant, D., Barnes, D., Janssen, M., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (20 October 2022). Physiological map to study kidney toxicity in the ONTOX project [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain. ![]() |
![]() ![]() | Barnes, D., Irvine, A., Gamba, A., Maia Ladeira, L. C., Staumont, B., Yang, H., Steffensen, I.-L., Geris, L., Janssen, M., & Masereeuw, R. (2022). Development of an adverse outcome pathway for kidney tubular necrosis. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV. ![]() |
![]() ![]() | Berkhout, J., Piersma, A., Legler, J., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Geris, L., & Heuseinkveld, H. (2022). Computational modelling of neural tube closure defects. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV. ![]() |
![]() ![]() | Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., Jiang, J., van Ertvelde, J., Jover, R., Vanhaecke, T., Mathieu, V., Geris, L., & Staumont, B. (2022). Developing a physiological map as a framework to study chemical- induced liver steatosis. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi. ![]() |
![]() ![]() | Gamba, A., Maia Ladeira, L. C., Lesage, R. L., Roodzant, D. L., Barnes, D. A., Janssen, M. J., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (2022). From Physiological Map to Ontology Unravelling Kidney Toxicity From Physiological Map to Ontology Unravelling Kidney Toxicity. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi. ![]() |
![]() ![]() | Maia Ladeira, L. C., Gamba, A., Lesage, R., Ertvelde, J. V., Jiang, J., Verhoeven, A., Roodzant, D., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Geris, L., & Staumont, B. (September 2022). P11-09 Physiology-based framework to study chemical-induced cholestasis. Toxicology Letters, 368, 165-S166. doi:10.1016/j.toxlet.2022.07.459 ![]() |
![]() ![]() | Kuchovska, E., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R., Steffensen, I.-L., Soop, G. L., Hofer, T., Myhre, O., Dirven, H., Geris, L., & Fritsche, E. (September 2022). SOC-II-09 First steps for creating an ontology for cognitive function defects for regulatory application. Toxicology Letters, 368, 35-S36. doi:10.1016/j.toxlet.2022.07.112 ![]() |
![]() ![]() | Staumont, B., Maia Ladeira, L. C., Gamba, A., Lesage, R., Verhoeven, A., Jiang, J., Ertvelde, J. V., Barnes, D. A., Janssen, M. J., Kuchovska, E., Berkhout, J., Roodzant, D., Teunis, M., Bozada, T., Luechtefeld, T. H., Jover, R., Vanhaecke, T., Vinken, M., Masereeuw, R., ... Geris, L. (September 2022). SOC-VI-08 Physiological maps: a benchmark tool for adverse outcome pathways and a cornerstone for the development of disease ontologies. Toxicology Letters, 368, 77-S78. doi:10.1016/j.toxlet.2022.07.228 ![]() |
![]() ![]() | Gamba, A., Maia Ladeira, L. C., Lesage, R., Barnes, D. A., Roodzant, D., Teunis, M., Janssen, M. J., Masereeuw, R., Geris, L., & Staumont, B. (2022). P04-06 New approaches for evaluating kidney toxicity using physiological maps. Toxicology Letters. doi:10.1016/j.toxlet.2022.07.290 ![]() |
![]() ![]() | Barnes, D., Irvine, A., Gamba, A., Staumont, B., Maia Ladeira, L. C., Yang, H., Steffensen, I.-L., Geris, L., Janssen, M., & Masereeuw, R. (September 2022). P01-07 Development of an adverse outcome pathway for kidney tubular necrosis. Toxicology Letters, 368, 86-S87. doi:10.1016/j.toxlet.2022.07.251 ![]() |
![]() ![]() | Manganelli, S., Gamba, A., Colombo, E., & Benfenati, E. (February 2022). Using VEGAHUB Within a Weight-of-Evidence Strategy. Methods in Molecular Biology, 2425, 479-495. doi:10.1007/978-1-0716-1960-5_18 ![]() |
![]() ![]() | Chayawan, Selvestrel, G., Baderna, D., Toma, C., Caballero Alfonso, A. Y., Gamba, A., & Benfenati, E. (January 2022). Skin sensitization quantitative QSAR models based on mechanistic structural alerts. Toxicology, 468, 153111. doi:10.1016/j.tox.2022.153111 ![]() |
![]() ![]() | Diomede, L., Beeg, M., Gamba, A., Fumagalli, O., Gobbi, M., & Salmona, M. (08 June 2021). Can Antiviral Activity of Licorice Help Fight COVID-19 Infection? Biomolecules, 11 (6), 855. doi:10.3390/biom11060855 ![]() |
![]() ![]() | Gamba, A., Salmona, M., & Bazzoni, G. (February 2021). The similarity of inherited diseases (I): clinical similarity within the phenotypic series. BMC Medical Genomics, 14 (1), 52. doi:10.1186/s12920-021-00900-7 ![]() |
![]() ![]() | Gamba, A., Salmona, M., Cantù, L., & Bazzoni, G. (September 2020). The similarity of inherited diseases (II): clinical and biological similarity between the phenotypic series. BMC Medical Genomics, 13 (1), 139. doi:10.1186/s12920-020-00793-y ![]() |
![]() ![]() | Gamba, A., Salmona, M., & Bazzoni, G. (June 2020). Quantitative analysis of proteins which are members of the same protein complex but cause locus heterogeneity in disease. Scientific Reports, 10 (1), 10423. doi:10.1038/s41598-020-66836-7 ![]() |
![]() ![]() | Carnesecchi, E., Raitano, G., Gamba, A., Benfenati, E., & Roncaglioni, A. (January 2020). Evaluation of non-commercial models for genotoxicity and carcinogenicity in the assessment of EFSA's databases. SAR and QSAR in Environmental Research, 31 (1), 33-48. doi:10.1080/1062936X.2019.1690045 ![]() |
![]() ![]() | Gini, G., Zanoli, F., Gamba, A., Raitano, G., & Benfenati, E. (August 2019). Could deep learning in neural networks improve the QSAR models? SAR and QSAR in Environmental Research, 30 (9), 617-642. doi:10.1080/1062936X.2019.1650827 ![]() |
![]() ![]() | Colombo, L., Gamba, A., Cantù, L., Salmona, M., Tagliavini, F., Rondelli, V., Del Favero, E., & Brocca, P. (May 2017). Pathogenic Aβ A2V versus protective Aβ A2T mutation: Early stage aggregation and membrane interaction. Biophysical Chemistry, 229, 11-18. doi:10.1016/j.bpc.2017.05.001 ![]() |
![]() ![]() | Morán, F., Vazquez, S., Xavier, D., Gamba, A., Bettinelli, P., & Montero, F. (10 October 2010). Online Suite of Web-tools to Process Stoichiometric Network Analysis: Tools-4- Metatool [Poster presentation]. ICSB 2010 - 11th International Conference on Systems Biology, Edimburgh, United Kingdom. ![]() |
![]() ![]() | Morán, F., Montero, F., Vázquez, S., Xavier, D., Gamba, A., & Bettinelli, P. (07 July 2010). Tools-4-Metatool. Online suite of web-tools to process stoichiometric network analysis data from METATOOL [Poster presentation]. IV Spanish Portuguese Biophysical Congress, Zaragoza, Spain. ![]() |