Gamba Alessio

GIGA Mol. Comput. Bio. - Biomecha. & Comput. Tissues Engin.

Département d'aérospatiale et mécanique > Génie biomécanique

See author's contact details
ORCID
0000-0002-9031-7508
Main Referenced Co-authors
Geris, Liesbet  (26)
Maia Ladeira, Luiz Carlos  (26)
Staumont, Bernard  (26)
Jover, Ramiro (9)
Teunis, Marc (9)
Main Referenced Keywords
Toxicology (7); toxicology (4); General Medicine (3); Genetics (3); Phenotype (3);
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (14)
Human health sciences: Multidisciplinary, general & others (9)
Life sciences: Multidisciplinary, general & others (7)
Computer science (2)
Environmental sciences & ecology (2)

Publications (total 37)

The most downloaded
156 downloads
Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., van Ertvelde, J., Jiang, J., Roodzant, D. L., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Heuseinkveld, H., Geris, L., & Staumont, B. (2022). Designing physiological maps as a tool to study liver toxicology. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV. https://hdl.handle.net/2268/299255

The most cited

33 citations (OpenAlex)

Gini, G., Zanoli, F., Gamba, A., Raitano, G., & Benfenati, E. (August 2019). Could deep learning in neural networks improve the QSAR models? SAR and QSAR in Environmental Research, 30 (9), 617-642. doi:10.1080/1062936X.2019.1650827 https://hdl.handle.net/2268/295688

Staumont, B., Maia Ladeira, L. C., Gamba, A., Heusinkveld, H. J., Piersma, A., Fritsche, E., Masereeuw, R., Vanhaecke, T., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vinken, M., & Geris, L. (2025). Mapping physiology: a systems biology approach for the development of alternative methods in toxicology. ALTEX: Alternatives to Animal Experimentation. doi:10.5281/zenodo.14278276
Editorial reviewed

Maia Ladeira, L. C., Verhoeven, A., van Ertvelde, J., Jiang, J., Gamba, A., Sanz Serrano, J., Vanhaecke, T., Heusinkveld, H. J., Jover, R., Vinken, M., Geris, L., & Staumont, B. (2024). Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/327181. doi:10.5281/zenodo.14515238

Maia Ladeira, L. C., Staumont, B., Gamba, A., & Geris, L. (2024). ONTOX's Physiological Maps Curation Guidelines. doi:10.5281/zenodo.13239453

Gamba, A., Maia Ladeira, L. C., Barnes, D. A., Janssen, M. J., Masereeuw, R., Geris, L., & Staumont, B. (September 2024). P05-50 Using ontology map and physiological map to improve predictive models for kidney toxicity. Toxicology Letters, 399, 151-S152. doi:10.1016/j.toxlet.2024.07.385
Peer Reviewed verified by ORBi

Kuchovska, E., Maia Ladeira, L. C., Bartmann, K., Polozij, D., Gorts, N., Corek, E., Donmez, A., Saborowski, L.-C., Bendt, F., Schade, M., Raad, G., Gamba, A., Staumont, B., Bal-Price, A., Wojewodzic, M., Lislien, M., Impelizzeri, A., Hofer, T., Dirven, H., ... Fritsche, E. (September 2024). S05-01 Functional mapping of neurodevelopmental disorders to ontology-based DNT NAMs for Next Generation Risk Assessment of chemicals. Toxicology Letters, 399, 18. doi:10.1016/j.toxlet.2024.07.056
Peer Reviewed verified by ORBi

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Serrano, J. S., Kuchovska, E., Berkhout, J., A., D., Teunis, M., Luechtefeld, T. H., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (September 2024). P05-45 Ontology maps: data integration tools for applications in toxicology. Toxicology Letters, 399, 149-S150. doi:10.1016/j.toxlet.2024.07.380
Peer Reviewed verified by ORBi

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Janssen, M. J., Teunis, M., Luechtefeld, T. H., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). Mapping Physiology As A Basis For Building Disease Ontology Maps. In 22ND INTERNATIONAL CONGRESS ESTIV BOOK OF ABSTRACTS. ESTIV.
Peer reviewed

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). From physiological maps to disease ontology maps using a systems biology approach. In Book of Abstracts. 3rd Annual Meeting of the ONTOX Project. ZENODO.
Peer reviewed

Staumont, B., Maia Ladeira, L. C., Gamba, A., Verhoeven, A., Sanz-Serrano, J., Kuchovska, E., Berkhout, J., Barnes, D. A., Teunis, M., Luechtefeld, T., Hartung, T., Jover, R., Vanhaecke, T., Fritsche, E., Heusinkveld, H. J., Piersma, A., Masereeuw, R., Vinken, M., & Geris, L. (2024). Building disease ontology maps: in silico tools for applications in toxicology. In VPH Conference 2024 Book of Abstracts. VPH2024.
Peer reviewed

Berkhout, J. H., Piersma, A., Legler, J., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R., Geris, L., Knudsen, T. B., Spencer, R. M., & Heusinkveld, H. J. (September 2023). P06-05: Towards a virtual embryo: Computational modelling of neural tube closure defects. Toxicology Letters, 384, 106. doi:10.1016/s0378-4274(23)00510-6
Peer Reviewed verified by ORBi

Gamba, A., Maia Ladeira, L. C., Lesage, R., Barnes, D. A., Janssen, M. J., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (September 2023). P06-36: The nephron physiological map as a tool to build kidney disease ontologies. Toxicology Letters, 384, 119. doi:10.1016/s0378-4274(23)00539-8
Peer Reviewed verified by ORBi

Maia Ladeira, L. C., Kuchovská, E., Görts, N., Hofer, T., Myhre, O., Lopez Soop, G. L. S., Dirven, H., Gamba, A., Lesage, R., Fritsche, E., Geris, L., & Staumont, B. (September 2023). LP-24: The Cognitive Function Defects Ontology: Integrating Biological, Toxicological, and Chemical Data for Next-Generation Risk Assessment. Toxicology Letters, 384, 316-S317. doi:10.1016/s0378-4274(23)00989-x
Peer Reviewed verified by ORBi

Kuchovska, E., Bartmann, K., Maia Ladeira, L. C., Dönmez, A., Saborowski, L.-C., Bendt, F., Schade, M., Raad, G., Lesage, R., Gamba, A., Staumont, B., Geris, L., & Fritsche, E. (September 2023). P22-35: Mapping of DNT NAMs’ signaling pathways in human physiology and disease for regulatory application. Toxicology Letters, 384, 264. doi:10.1016/s0378-4274(23)00868-8
Peer Reviewed verified by ORBi

Kuchovska, E., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Steffensen, I.-L., Soop, G. L., Hofer, T., Myhre, O., Dirven, H., Geris, L., & Fritsche, E. (24 November 2022). FIRST STEPS FOR CREATING AN ONTOLOGY FOR COGNITIVE FUNCTION DEFECTS FOR REGULATORY APPLICATION [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain.
Editorial reviewed

Maia Ladeira, L. C.* , Gamba, A.* , Lesage, R., Kuchovska, E., Görts, N., Verhoeven, A., Jiang, J., van Ertvelde, J., Barnes, D., Janssen, M., Berkhout, J., Roodzant, D., Teunis, M., Bozada, T. J., Luechtefeld, T., Jover, R., Vanhaecke, T., Vinken, M., Masereeuw, R., ... Staumont, B. (24 November 2022). Physiological maps and chemical-induced disease ontologies: tools to support NAMs development for next-generation risk assessment [Poster presentation]. ASPIS Open Symposium, Sitges, Spain.
Editorial reviewed
* These authors have contributed equally to this work.

Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., van Ertvelde, J., Jiang, J., Roodzant, D. L., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Heuseinkveld, H., Geris, L., & Staumont, B. (2022). Designing physiological maps as a tool to study liver toxicology. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.
Editorial reviewed

Gamba, A., Maia Ladeira, L. C., Lesage, R., Roodzant, D., Barnes, D., Janssen, M., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (20 October 2022). Physiological map to study kidney toxicity in the ONTOX project [Poster presentation]. 21st International Congress ESTIV, Sitges, Spain.
Editorial reviewed

Barnes, D., Irvine, A., Gamba, A., Maia Ladeira, L. C., Staumont, B., Yang, H., Steffensen, I.-L., Geris, L., Janssen, M., & Masereeuw, R. (2022). Development of an adverse outcome pathway for kidney tubular necrosis. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.
Editorial reviewed

Berkhout, J., Piersma, A., Legler, J., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R. L., Geris, L., & Heuseinkveld, H. (2022). Computational modelling of neural tube closure defects. In Helena Kandarova & João Barroso, 21st International Congress ESTIV Abstract Book. Bratslava, Slovakia: ESTIV.
Editorial reviewed

Maia Ladeira, L. C., Gamba, A., Lesage, R. L., Verhoeven, A., Jiang, J., van Ertvelde, J., Jover, R., Vanhaecke, T., Mathieu, V., Geris, L., & Staumont, B. (2022). Developing a physiological map as a framework to study chemical- induced liver steatosis. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi.
Editorial reviewed

Gamba, A., Maia Ladeira, L. C., Lesage, R. L., Roodzant, D. L., Barnes, D. A., Janssen, M. J., Teunis, M., Masereeuw, R., Geris, L., & Staumont, B. (2022). From Physiological Map to Ontology Unravelling Kidney Toxicity From Physiological Map to Ontology Unravelling Kidney Toxicity. In VPHi, VPH2022 Virtual Physiological Human Conference. Brussels, Belgium: VPHi.
Editorial reviewed

Maia Ladeira, L. C., Gamba, A., Lesage, R., Ertvelde, J. V., Jiang, J., Verhoeven, A., Roodzant, D., Teunis, M., Jover, R., Vanhaecke, T., Vinken, M., Geris, L., & Staumont, B. (September 2022). P11-09 Physiology-based framework to study chemical-induced cholestasis. Toxicology Letters, 368, 165-S166. doi:10.1016/j.toxlet.2022.07.459
Peer Reviewed verified by ORBi

Kuchovska, E., Gamba, A., Maia Ladeira, L. C., Staumont, B., Lesage, R., Steffensen, I.-L., Soop, G. L., Hofer, T., Myhre, O., Dirven, H., Geris, L., & Fritsche, E. (September 2022). SOC-II-09 First steps for creating an ontology for cognitive function defects for regulatory application. Toxicology Letters, 368, 35-S36. doi:10.1016/j.toxlet.2022.07.112
Peer Reviewed verified by ORBi

Staumont, B., Maia Ladeira, L. C., Gamba, A., Lesage, R., Verhoeven, A., Jiang, J., Ertvelde, J. V., Barnes, D. A., Janssen, M. J., Kuchovska, E., Berkhout, J., Roodzant, D., Teunis, M., Bozada, T., Luechtefeld, T. H., Jover, R., Vanhaecke, T., Vinken, M., Masereeuw, R., ... Geris, L. (September 2022). SOC-VI-08 Physiological maps: a benchmark tool for adverse outcome pathways and a cornerstone for the development of disease ontologies. Toxicology Letters, 368, 77-S78. doi:10.1016/j.toxlet.2022.07.228
Peer Reviewed verified by ORBi

Gamba, A., Maia Ladeira, L. C., Lesage, R., Barnes, D. A., Roodzant, D., Teunis, M., Janssen, M. J., Masereeuw, R., Geris, L., & Staumont, B. (2022). P04-06 New approaches for evaluating kidney toxicity using physiological maps. Toxicology Letters. doi:10.1016/j.toxlet.2022.07.290
Peer Reviewed verified by ORBi

Barnes, D., Irvine, A., Gamba, A., Staumont, B., Maia Ladeira, L. C., Yang, H., Steffensen, I.-L., Geris, L., Janssen, M., & Masereeuw, R. (September 2022). P01-07 Development of an adverse outcome pathway for kidney tubular necrosis. Toxicology Letters, 368, 86-S87. doi:10.1016/j.toxlet.2022.07.251
Peer Reviewed verified by ORBi

Manganelli, S., Gamba, A., Colombo, E., & Benfenati, E. (February 2022). Using VEGAHUB Within a Weight-of-Evidence Strategy. Methods in Molecular Biology, 2425, 479-495. doi:10.1007/978-1-0716-1960-5_18
Peer Reviewed verified by ORBi

Chayawan, Selvestrel, G., Baderna, D., Toma, C., Caballero Alfonso, A. Y., Gamba, A., & Benfenati, E. (January 2022). Skin sensitization quantitative QSAR models based on mechanistic structural alerts. Toxicology, 468, 153111. doi:10.1016/j.tox.2022.153111
Peer Reviewed verified by ORBi

Diomede, L., Beeg, M., Gamba, A., Fumagalli, O., Gobbi, M., & Salmona, M. (08 June 2021). Can Antiviral Activity of Licorice Help Fight COVID-19 Infection? Biomolecules, 11 (6), 855. doi:10.3390/biom11060855
Peer Reviewed verified by ORBi

Gamba, A., Salmona, M., & Bazzoni, G. (February 2021). The similarity of inherited diseases (I): clinical similarity within the phenotypic series. BMC Medical Genomics, 14 (1), 52. doi:10.1186/s12920-021-00900-7
Peer Reviewed verified by ORBi

Gamba, A., Salmona, M., Cantù, L., & Bazzoni, G. (September 2020). The similarity of inherited diseases (II): clinical and biological similarity between the phenotypic series. BMC Medical Genomics, 13 (1), 139. doi:10.1186/s12920-020-00793-y
Peer Reviewed verified by ORBi

Gamba, A., Salmona, M., & Bazzoni, G. (June 2020). Quantitative analysis of proteins which are members of the same protein complex but cause locus heterogeneity in disease. Scientific Reports, 10 (1), 10423. doi:10.1038/s41598-020-66836-7
Peer Reviewed verified by ORBi

Carnesecchi, E., Raitano, G., Gamba, A., Benfenati, E., & Roncaglioni, A. (January 2020). Evaluation of non-commercial models for genotoxicity and carcinogenicity in the assessment of EFSA's databases. SAR and QSAR in Environmental Research, 31 (1), 33-48. doi:10.1080/1062936X.2019.1690045
Peer Reviewed verified by ORBi

Gini, G., Zanoli, F., Gamba, A., Raitano, G., & Benfenati, E. (August 2019). Could deep learning in neural networks improve the QSAR models? SAR and QSAR in Environmental Research, 30 (9), 617-642. doi:10.1080/1062936X.2019.1650827
Peer Reviewed verified by ORBi

Colombo, L., Gamba, A., Cantù, L., Salmona, M., Tagliavini, F., Rondelli, V., Del Favero, E., & Brocca, P. (May 2017). Pathogenic Aβ A2V versus protective Aβ A2T mutation: Early stage aggregation and membrane interaction. Biophysical Chemistry, 229, 11-18. doi:10.1016/j.bpc.2017.05.001
Peer Reviewed verified by ORBi

Morán, F., Vazquez, S., Xavier, D., Gamba, A., Bettinelli, P., & Montero, F. (10 October 2010). Online Suite of Web-tools to Process Stoichiometric Network Analysis: Tools-4- Metatool [Poster presentation]. ICSB 2010 - 11th International Conference on Systems Biology, Edimburgh, United Kingdom.
Peer reviewed

Morán, F., Montero, F., Vázquez, S., Xavier, D., Gamba, A., & Bettinelli, P. (07 July 2010). Tools-4-Metatool. Online suite of web-tools to process stoichiometric network analysis data from METATOOL [Poster presentation]. IV Spanish Portuguese Biophysical Congress, Zaragoza, Spain.
Peer reviewed

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