![]() ![]() | Goffin, E., Fraikin, P., Abboud, D., De Tullio, P., Beaufour, C., Botez, I., Hanson, J., Danober, L., Francotte, P., & Pirotte, B. (15 March 2023). New insights in the development of positive allosteric modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors belonging to 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides: Introduction of (mono/difluoro)methyl groups at the 2-position of the thiadiazine ring. European Journal of Medicinal Chemistry, 250, 115221. doi:10.1016/j.ejmech.2023.115221 ![]() |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (April 2022). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion. Poster session presented at Keystone Symposia Conference, GPCRs: An Odyssey from Structure, Signaling and Regulation to Therapeutics, Snowbird, United States. |
![]() ![]() | Franke, M.* , Daly, A.* , Gonon Rodrigues Palmeira, L., Tirosh, A., Stigliano, A., Trifan, E., Faucz, F. R., Abboud, D., PETROSSIANS, P., Tena, J. J., Vitali, E., Lania, A. G., Gómez-Skarmeta, J. L., BECKERS, A.* , Stratakis, C. A.* , & Trivellin, G.*. (2022). Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism. American Journal of Human Genetics. doi:10.1016/j.ajhg.2022.02.002 ![]() * These authors have contributed equally to this work. |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (February 2022). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion. Paper presented at CIRM day, Liege, Belgium. |
![]() ![]() | D'Uonnolo, G., Reynders, N., Meyrath, M., Abboud, D., Uchański, T., Laeremans, T., Volkman, B. F., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (2022). The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B. Frontiers in Immunology, 13, 868579. doi:10.3389/fimmu.2022.868579 ![]() |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (October 2021). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion. Poster session presented at 5th ERNEST meeting, Bari, Italy. |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (July 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Poster session presented at 1st Transatlantic ECI GPCR symposium. |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (May 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at FASEB, The Growth Hormone (GH)/ Prolactin (PRL) Family in Biology & Disease Conference. |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at 4th ERNEST meeting. |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at Belgian Society of Physiology and Pharmacology. |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Poster session presented at American Society for Pharmacology and Experimental Therapeutics (ASPET), GPCR colloquium. |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (November 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at GDR3545. |
![]() ![]() | Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (21 September 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Nature Communications, 11 (1), 4752. doi:10.1038/s41467-020-18500-x ![]() |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at 9TH GDR3545 GPCR INTERNATIONAL MEETING. |
Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (December 2019). GPR101 orphan receptor in XLAG syndrome. Paper presented at CIRM day. |
Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (July 2019). Pharmacology of GPR101 orphan receptor. Paper presented at Transardennaise de l’hypophyse. |
![]() ![]() | Reynders, N., Abboud, D., Baragli, A., Noman, M. Z., Rogister, B., Niclou, S., Heveker, N., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (18 June 2019). The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment. Cells, 8 (6). ![]() |
Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (May 2019). GPR101 orphan receptor in XLAG syndrome. Paper presented at Belgian Society of Physiology and Pharmacology. |
![]() ![]() | Vandevoorde, S., Abboud, D., Laschet, C., Daly, A., Hanson, J., & Beckers, A. (May 2019). SOMATOSTATIN ANALOGUE RESISTANCE IN X-LAG SYNDROME - IDENTIFICATION OF THE UNDERLYING MECHANISMS. Poster session presented at Spring meeting 2019 Belgian Society of Physiology and Pharmacology, Bruxelles, Belgium. |
Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (December 2018). GPR101 orphan receptor in XLAG syndrome. Paper presented at CIRM day. |
![]() ![]() | Regenass, P., Abboud, D., Daubeuf, F., Lehalle, C., Gizzi, P., Riché, S., Hachet-Haas, M., Rohmer, F., Gasparik, V., Boeglin, D., Haeich, J., Knehans, T., Rognan, D., Heissler, D., Marsol, C., Villa, P., Galzi, J.-L., Hibert, M., Frossard, N., & Bonnet, D. (14 August 2018). Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. Journal of Medicinal Chemistry, 61, 7671-7686. doi:10.1021/acs.jmedchem.8b00657 ![]() |
Abboud, D., Daly, A., Laschet, C., Pirotte, B., BECKERS, A., & Hanson, J. (05 July 2018). GPR101 orphan receptor: a novel cause of growth hormone deregulation. Paper presented at World Congress of Basic and Clinical Pharmacology WCP 2018- IUPHAR, Kyoto, Japan. |
Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (July 2018). The orphan receptor GPR101 as a novel cause of growth hormone deregulation. Poster session presented at 18th International Union of Basic and Clinical Pharmacology (IUPHAR) congress. |
![]() ![]() | Laschet, C., Dupuis, N., Geubelle, P., Abboud, D., & Hanson, J. (September 2017). Targeted mutagenesis of orphan GPCRs of the SREB family. Poster session presented at International Symposium on GPCRs and G-proteins, Bonn, Germany. |
Abboud, D., Daly, A., Laschet, C., Pirotte, B., BECKERS, A., & Hanson, J. (07 July 2017). Pharmacology of GPR101. Paper presented at Transardennaise de l'hypophyse, Liège, Belgium. |
![]() ![]() | Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (May 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation. Poster session presented at 19th European Congress of Endocrinology, Lisbon, Portugal. |
![]() ![]() | Geubelle, P., Gilissen, J., Dilly, S., POMA, L., Dupuis, N., Laschet, C., Abboud, D., Inoue, A., Jouret, F., Pirotte, B., & Hanson, J. (May 2017). Identification and pharmacological characterization of succinate receptor agonists. British Journal of Pharmacology, 174 (9), 796-808. doi:10.1111/bph.13738 ![]() |
Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (April 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation. Poster session presented at Belgian Society of Physiology and Pharmacology, Bruxelles, Belgium. |
![]() ![]() | Abboud, D., & Hanson, J. (April 2017). Chemokine neutralization as an innovative therapeutic strategy for atopic dermatitis. Drug Discovery Today, 22 (4), 702-7011. doi:10.1016/j.drudis.2016.11.023 ![]() |
Abboud, D., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., & Hanson, J. (November 2016). GPR101 orphan GPCR: a novel cause of growth hormone deregulation. Poster session presented at Fifth annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med), Tours, France. |
Dupuis, N., Franssen, D., Laschet, C., Geubelle, P., Soni, A., Abboud, D., Twizere, J.-C., Pirotte, B., & Hanson, J. (26 September 2016). Small molecule ligands for the orphan GPR27. Poster session presented at GLISTEN meeting 2016 in Prague. |
![]() ![]() | Laschet, C., Dupuis, N., Soni, A., Geubelle, P., Abboud, D., & Hanson, J. (September 2016). Targeted mutagenesis of orphan GPCRs of the SREB family. Poster session presented at GLISTEN 2016 in Prague. |
![]() ![]() | Abboud, D., Frossard, N., Galzi, J.-L., Bernard, P., Do, Q.-T., & Pillard, C. (31 March 2016). Composition contenant au moins un inhibiteur de certaines chimiokines, son procédé d’obtention et son utilisation en dermo-cosmétique pharmaceutique. |
![]() ![]() | Abboud, D., Do, Q.-T., Frossard, N., Galzi, J.-L., Bernard, P., & Pillard, C. (31 March 2016). Utilisation dermocosmétique ou pharmaceutique d'une composition contenant au moins un inhibiteur de certaines chimiokines. |
![]() ![]() | Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Villa, P., Haiech, J., Bonnet, D., Hibert, M., Bernard, P., Galzi, J.-L., & Frossard, N. (07 October 2015). A strategy to discover decoy chemokine ligands with an anti-inflammatory activity. Scientific Reports, 5, 14746. doi:10.1038/srep14746 ![]() |
Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bonnet, D., Hibert, M., Bernard, P., Frossard, N., & Galzi, J.-L. (August 2015). Combating skin inflammation with CXCL12 chemokine neutraligands. Paper presented at 12th World Congress on Inflammation, “Harnessing Patterns of Inflammation in Pursuit of Novel Therapeutics”. |
Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bonnet, D., Hibert, M., Bernard, P., Frossard, N., & Galzi, J.-L. (December 2014). A kinetic-based method to discover chemokine neutraligands. Paper presented at Troisième Journée Scientifique Publique de Medalis. |
Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (November 2014). Novel chemokine neutraligands targeting atopic dermatitis. Paper presented at SPIM Skin Physiology International Meeting. |
Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (October 2014). Novel CCL17 chemokine neutraligands targeting atopic diseases. Poster session presented at J2R journée des maladies respiratoires. |
Abboud, D. (2014). Rôle des chimiokines dans les maladies atopiques: Etude pharmacologique à l’aide des neutraligands. Unpublished doctoral thesis, Université de Strasbourg. Jury: Galzi, J.-L. (Promotor), Bernard, P. (Promotor), Kilhofer, M.-C., ... Pin, J.-P. |
Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (June 2014). Novel CCL17 chemokine neutraligands targeting atopic diseases. Paper presented at Lungstorming. |
Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (October 2013). Novel chemokine neutraligands targeting atopic dermatitis. Poster session presented at Second annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med). |
Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (July 2013). Novel chemokine neutraligands targeting atopic diseases. Poster session presented at RICT/Société de Chimie Thérapeutique (SCT) - « Drug Discovery and Selection »
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Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (June 2013). Identification de neutraligands des chimiokines de CCL17 et CCL22 impliquées dans les maladies atopiques. Paper presented at Lungstorming. |
Abboud, D., François, D., Utard, V., Frossard, N., & Galzi, J.-L. (October 2012). Novel CCL17 and CCL22 chemokine neutraligands targeting atopic dermatitis. Poster session presented at First annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med). |
Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (September 2012). How and why to find chemokine neutraligands? Paper presented at EMBO Conference Series « Chemical Biology 2012 ». |
Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (May 2012). Chemokines and atopic dermatitis. Poster session presented at Gordon Research Conferences, « chemotactic cytokines, molecular and cellular mechanisms in health and disease ». |
Abboud, D., Daubeuf, F., Utard, V., Frossard, N., Bonnet, D., Hibert, M., & Galzi, J.-L. (March 2012). Novel CCL17 chemokine neutraligands targeting atopic dermatitis. Paper presented at Première Journée scientifique publique de Medalis. |
Abboud, D. (2010). Stability of parabens in breast cancer cells homogenates (MCF-7). Unpublished master thesis, Université Libanaise, Hadass, Lebanon. Jury: Greiges, H. (Promotor), ... Dagher, Z. |