Profil

Abboud Dayana

Département de pharmacie

Département de pharmacie > GIGA Molecular Biology of Diseases - Molecular Pharmacology

See author's contact details
ORCID
0000-0003-4176-0631

Main Research Fields
Biochemistry, biophysics & molecular biology
Pharmacy, pharmacology & toxicology
Endocrinology, metabolism & nutrition
Dermatology
Anatomy (cytology, histology, embryology...) & physiology
Main Keywords
ACKR2; ACKR3; Alternative Splicing; arrestin; beta-Arrestins;
Main Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
GIGA - molecular biology of disease
GIGA Molecular Biology of Diseases - ULiège
Main Co-authors
Hanson, Julien 
Pirotte, Bernard 
Beckers, Albert 
Daly, Adrian 
Frossard, Nelly

Publications (total 48)

The most downloaded
107 downloads
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (21 September 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Nature Communications, 11 (1), 4752. doi:10.1038/s41467-020-18500-x https://hdl.handle.net/2268/251225
The most cited
42 citations (SCOPUS)
Reynders, N., Abboud, D., Baragli, A., Noman, M. Z., Rogister, B., Niclou, S., Heveker, N., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (18 June 2019). The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment. Cells, 8 (6). https://hdl.handle.net/2268/238128

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (April 2022). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion. Poster session presented at Keystone Symposia Conference, GPCRs: An Odyssey from Structure, Signaling and Regulation to Therapeutics, Snowbird, United States.

Franke, M.* , Daly, A.* , Gonon Rodrigues Palmeira, L., Tirosh, A., Stigliano, A., Trifan, E., Faucz, F. R., Abboud, D., PETROSSIANS, P., Tena, J. J., Vitali, E., Lania, A. G., Gómez-Skarmeta, J. L., BECKERS, A.* , Stratakis, C. A.* , & Trivellin, G.*. (2022). Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism. American Journal of Human Genetics. doi:10.1016/j.ajhg.2022.02.002
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (February 2022). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion. Paper presented at CIRM day, Liege, Belgium.

D'Uonnolo, G., Reynders, N., Meyrath, M., Abboud, D., Uchański, T., Laeremans, T., Volkman, B. F., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (2022). The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B. Frontiers in Immunology, 13, 868579. doi:10.3389/fimmu.2022.868579
Peer Reviewed verified by ORBi

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (October 2021). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion. Poster session presented at 5th ERNEST meeting, Bari, Italy.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (July 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Poster session presented at 1st Transatlantic ECI GPCR symposium.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (May 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at FASEB, The Growth Hormone (GH)/ Prolactin (PRL) Family in Biology & Disease Conference.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at 4th ERNEST meeting.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Poster session presented at American Society for Pharmacology and Experimental Therapeutics (ASPET), GPCR colloquium.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at Belgian Society of Physiology and Pharmacology.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (November 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at GDR3545.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (21 September 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Nature Communications, 11 (1), 4752. doi:10.1038/s41467-020-18500-x
Peer Reviewed verified by ORBi

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Paper presented at 9TH GDR3545 GPCR INTERNATIONAL MEETING.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (December 2019). GPR101 orphan receptor in XLAG syndrome. Paper presented at CIRM day.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (July 2019). Pharmacology of GPR101 orphan receptor. Paper presented at Transardennaise de l’hypophyse.

Reynders, N., Abboud, D., Baragli, A., Noman, M. Z., Rogister, B., Niclou, S., Heveker, N., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (18 June 2019). The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment. Cells, 8 (6).
Peer Reviewed verified by ORBi

Vandevoorde, S., Abboud, D., Laschet, C., Daly, A., Hanson, J., & Beckers, A. (May 2019). SOMATOSTATIN ANALOGUE RESISTANCE IN X-LAG SYNDROME - IDENTIFICATION OF THE UNDERLYING MECHANISMS. Poster session presented at Spring meeting 2019 Belgian Society of Physiology and Pharmacology, Bruxelles, Belgium.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (May 2019). GPR101 orphan receptor in XLAG syndrome. Paper presented at Belgian Society of Physiology and Pharmacology.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (December 2018). GPR101 orphan receptor in XLAG syndrome. Paper presented at CIRM day.

Regenass, P., Abboud, D., Daubeuf, F., Lehalle, C., Gizzi, P., Riché, S., Hachet-Haas, M., Rohmer, F., Gasparik, V., Boeglin, D., Haeich, J., Knehans, T., Rognan, D., Heissler, D., Marsol, C., Villa, P., Galzi, J.-L., Hibert, M., Frossard, N., & Bonnet, D. (14 August 2018). Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. Journal of Medicinal Chemistry, 61, 7671-7686. doi:10.1021/acs.jmedchem.8b00657
Peer Reviewed verified by ORBi

Abboud, D., Daly, A., Laschet, C., Pirotte, B., BECKERS, A., & Hanson, J. (05 July 2018). GPR101 orphan receptor: a novel cause of growth hormone deregulation. Paper presented at World Congress of Basic and Clinical Pharmacology WCP 2018- IUPHAR, Kyoto, Japan.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (July 2018). The orphan receptor GPR101 as a novel cause of growth hormone deregulation. Poster session presented at 18th International Union of Basic and Clinical Pharmacology (IUPHAR) congress.

Laschet, C., Dupuis, N., Geubelle, P., Abboud, D., & Hanson, J. (September 2017). Targeted mutagenesis of orphan GPCRs of the SREB family. Poster session presented at International Symposium on GPCRs and G-proteins, Bonn, Germany.

Abboud, D., Daly, A., Laschet, C., Pirotte, B., BECKERS, A., & Hanson, J. (07 July 2017). Pharmacology of GPR101. Paper presented at Transardennaise de l'hypophyse, Liège, Belgium.

Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (May 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation. Poster session presented at 19th European Congress of Endocrinology, Lisbon, Portugal.

Geubelle, P., Gilissen, J., Dilly, S., POMA, L., Dupuis, N., Laschet, C., Abboud, D., Inoue, A., Jouret, F., Pirotte, B., & Hanson, J. (May 2017). Identification and pharmacological characterization of succinate receptor agonists. British Journal of Pharmacology, 174 (9), 796-808. doi:10.1111/bph.13738
Peer Reviewed verified by ORBi

Abboud, D., & Hanson, J. (April 2017). Chemokine neutralization as an innovative therapeutic strategy for atopic dermatitis. Drug Discovery Today, 22 (4), 702-7011. doi:10.1016/j.drudis.2016.11.023
Peer Reviewed verified by ORBi

Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (April 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation. Poster session presented at Belgian Society of Physiology and Pharmacology, Bruxelles, Belgium.

Abboud, D., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., & Hanson, J. (November 2016). GPR101 orphan GPCR: a novel cause of growth hormone deregulation. Poster session presented at Fifth annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med), Tours, France.

Dupuis, N., Franssen, D., Laschet, C., Geubelle, P., Soni, A., Abboud, D., Twizere, J.-C., Pirotte, B., & Hanson, J. (26 September 2016). Small molecule ligands for the orphan GPR27. Poster session presented at GLISTEN meeting 2016 in Prague.

Laschet, C., Dupuis, N., Soni, A., Geubelle, P., Abboud, D., & Hanson, J. (September 2016). Targeted mutagenesis of orphan GPCRs of the SREB family. Poster session presented at GLISTEN 2016 in Prague.

Abboud, D., Do, Q.-T., Frossard, N., Galzi, J.-L., Bernard, P., & Pillard, C. (31 March 2016). Utilisation dermocosmétique ou pharmaceutique d'une composition contenant au moins un inhibiteur de certaines chimiokines.

Abboud, D., Frossard, N., Galzi, J.-L., Bernard, P., Do, Q.-T., & Pillard, C. (31 March 2016). Composition contenant au moins un inhibiteur de certaines chimiokines, son procédé d’obtention et son utilisation en dermo-cosmétique pharmaceutique.

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Villa, P., Haiech, J., Bonnet, D., Hibert, M., Bernard, P., Galzi, J.-L., & Frossard, N. (07 October 2015). A strategy to discover decoy chemokine ligands with an anti-inflammatory activity. Scientific Reports, 5, 14746. doi:10.1038/srep14746
Peer Reviewed verified by ORBi

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bonnet, D., Hibert, M., Bernard, P., Frossard, N., & Galzi, J.-L. (August 2015). Combating skin inflammation with CXCL12 chemokine neutraligands. Paper presented at 12th World Congress on Inflammation, “Harnessing Patterns of Inflammation in Pursuit of Novel Therapeutics”.

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bonnet, D., Hibert, M., Bernard, P., Frossard, N., & Galzi, J.-L. (December 2014). A kinetic-based method to discover chemokine neutraligands. Paper presented at Troisième Journée Scientifique Publique de Medalis.

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (November 2014). Novel chemokine neutraligands targeting atopic dermatitis. Paper presented at SPIM Skin Physiology International Meeting.

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (October 2014). Novel CCL17 chemokine neutraligands targeting atopic diseases. Poster session presented at J2R journée des maladies respiratoires.

Abboud, D. (2014). Rôle des chimiokines dans les maladies atopiques: Etude pharmacologique à l’aide des neutraligands. Unpublished doctoral thesis, Université de Strasbourg.
Jury: Galzi, J.-L. (Promotor), Bernard, P. (Promotor), Kilhofer, M.-C., & Pin, J.-P.

Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (June 2014). Novel CCL17 chemokine neutraligands targeting atopic diseases. Paper presented at Lungstorming.

Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (October 2013). Novel chemokine neutraligands targeting atopic dermatitis. Poster session presented at Second annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med).

Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (July 2013). Novel chemokine neutraligands targeting atopic diseases. Poster session presented at RICT/Société de Chimie Thérapeutique (SCT) - « Drug Discovery and Selection »
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Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (June 2013). Identification de neutraligands des chimiokines de CCL17 et CCL22 impliquées dans les maladies atopiques. Paper presented at Lungstorming.

Abboud, D., François, D., Utard, V., Frossard, N., & Galzi, J.-L. (October 2012). Novel CCL17 and CCL22 chemokine neutraligands targeting atopic dermatitis. Poster session presented at First annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med).

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (September 2012). How and why to find chemokine neutraligands? Paper presented at EMBO Conference Series « Chemical Biology 2012 ».

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (May 2012). Chemokines and atopic dermatitis. Poster session presented at Gordon Research Conferences, « chemotactic cytokines, molecular and cellular mechanisms in health and disease ».

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., Bonnet, D., Hibert, M., & Galzi, J.-L. (March 2012). Novel CCL17 chemokine neutraligands targeting atopic dermatitis. Paper presented at Première Journée scientifique publique de Medalis.

Abboud, D. (2010). Stability of parabens in breast cancer cells homogenates (MCF-7). Unpublished master thesis, Université Libanaise, Hadass, Lebanon.
Jury: Greiges, H. (Promotor), & Dagher, Z.

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