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LEBEAU Alizée

Département de médecine interne > Service d'oncologie médicale

See author's contact details
ORCID
0000-0002-1144-3232
Main Referenced Co-authors
Bruyère, Diane  (20)
Herfs, Michael  (20)
Delvenne, Philippe  (19)
Hubert, Pascale  (19)
Roncarati, Patrick  (19)
Main Referenced Keywords
Molecular Medicine (4); Pharmacology (4); Cancer (3); HPV (3); Mice (3);
Main Referenced Unit & Research Centers
Giga-Cancer - ULiège (3)
Main Referenced Disciplines
Oncology (34)
Biochemistry, biophysics & molecular biology (10)
Anatomy (cytology, histology, embryology...) & physiology (3)
Cardiovascular & respiratory systems (1)
Hematology (1)

Publications (total 52)

The most downloaded
135 downloads
Gucciardo, F.* , Pirson, S.* , Baudin, L., Lebeau, A., & Noël, A. (22 April 2022). uPARAP/Endo180: a multifaceted protein of mesenchymal cells. Cellular and Molecular Life Sciences, 79 (5), 255. doi:10.1007/s00018-022-04249-7 https://hdl.handle.net/2268/290556

The most cited

132 citations (OpenAlex)

Hubert, P., RONCARATI, P., Demoulin, S., Pilard, C., Ancion, M., Reynders, C., Lerho, T., Bruyère, D., Lebeau, A., Radermecker, C., Meunier, M., Nokin, M.-J., Hendrick, E., Peulen, O., Delvenne, P., & Herfs, M. (2021). Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy. Journal for ImmunoTherapy of Cancer, 9 ((3)), 001966. doi:10.1136/jitc-2020-001966 https://hdl.handle.net/2268/258085

Gennigens, C., & LEBEAU, A. (2025). Emerging therapies in gynaecological cancers (part 2): Endometrial cancer - Adjuvant and metastatic settings. Belgian Journal of Medical Oncology.
Editorial reviewed

Gucciardo, F.* , Lebeau, A.* , Pirson, S.* , Buntinx, F.* , Ivanova, E.* , Blacher, S., Brouillard, P., Deroye, J., Baudin, L., Pirnay, A., Morfoisse, F., Villette, C., Nizet, C., Lallemand, F., Munaut, C., Alitalo, K., Geris, L., Vikkula, M., Gautier-Isola, M.* , & Noël, A.*. (13 May 2025). Targeting uPARAP Modifies Lymphatic Vessel Architecture and Attenuates Lymphedema. Circulation, 151, 1412-1429. doi:10.1161/CIRCULATIONAHA.124.072093
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Gennigens, C., & LEBEAU, A. (May 2025). Emerging therapies in gynaecological cancers (part 1) : Locally advanced and metastatic cervical cancer. Belgian Journal of Medical Oncology, 19 (3), 88-95.
Editorial reviewed

Pilard, C., RONCARATI, P., Ancion, M., Luyckx, M., Renard, M., Reynders, C., Lerho, T., Poulain, F., Bruyère, D., LEBEAU, A., Hendrick, E., Crake, R., Peiffer, R., Nokin, M.-J., Peulen, O., Delvenne, P., Hubert, P.* , & Herfs, M.*. (13 March 2025). RANKL blockade inhibits cancer growth through reversing the tolerogenic profile of tumor-infiltrating (plasmacytoid) dendritic cells. Journal for ImmunoTherapy of Cancer, 13 (3), 010753. doi:10.1136/jitc-2024-010753
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pirson, S.* , Gautier-Isola, M.* , Baudin, L., Rouaud, L., Vanwynsberghe, A., Deroye, J., Bekisz, S., Gucciardo, F., LEBEAU, A., Buntinx, F., Ivanova, E., Staumont, B., Blacher, S., Gilles, C.* , & Noël, A.*. (27 February 2025). AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway. Cellular and Molecular Life Sciences, 82 (1), 95. doi:10.1007/s00018-024-05542-3
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Goffinet, L., Geraerts, A., LEBEAU, A., Seidel, L., Darimont, C., Meuris, F., Pauwen, S., Delbecque, K., Gonne, E., Goffin, F., Lovinfosse, P., Danthine, D., Kakkos, A., Kridelka, F., & Gennigens, C. (February 2025). Impact Of Lymph Node Assessment On Survival Outcomes In Locally Advanced Cervical Cancer : A Retrospective Study. International Journal of Gynecological Cancer, 35 (2), 100547. doi:10.1016/j.ijgc.2024.100547

Gonne, E., Goffinet, L., Geraerts, A., LEBEAU, A., Pleyers, C., Seidel, L., Pauwen, S., Darimont, C., Meuris, F., PIRON, M., Kakkos, A., Schoenen, S., Goffin, F., Delbecque, K., Lovinfosse, P., Danthine, D., Kridelka, F., & Gennigens, C. (February 2025). Survival Of Patients Over 70 Years Old With Locally Advanced Cervical Cancer : A Retrospective Analysis. International Journal of Gynecological Cancer, 35 (2), 100518. doi:10.1016/j.ijgc.2024.100518

LEBEAU, A., Goffinet, L., Geraerts, A., Pleyers, C., Gonne, E., Seidel, L., Pauwen, S., Darimont, C., Meuris, F., PIRON, M., Kakkos, A., Schoenen, S., Goffin, F., Delbecque, K., Lovinfosse, P., Danthine, D., Kridelka, F., & Gennigens, C. (2025). Analysis Of Tumour Characteristics Associated With Visceral Recurrence In Locally Advanced Cervical Cancer. International Journal of Gynecological Cancer. doi:10.1016/j.ijgc.2024.100501

Geraerts, A., Goffinet, L., LEBEAU, A., Darimont, C., Meuris, F., Pauwen, S., Delbecque, K., Gonne, E., Goffin, F., Seidel, L., Lovinfosse, P., Danthine, D., Kakkos, A., Kridelka, F., & Gennigens, C. (February 2025). Correlation Between Hematological Parameters And Outcome In Patients With Locally Advanced Cervical Cancer Treated By Concomitant Chemoradiotherapy Followed By Brachytherapy. International Journal of Gynecological Cancer, 35 (2), 100527. doi:10.1016/j.ijgc.2024.100527

LAPAILLE, L., Lenom, M., Gonne, E., PIRON, M., Goffin, F., Kakkos, A., Schoenen, S., Kridelka, F., Delbecque, K., PLEYERS, C., Seidel, L., Lovinfosse, P., Danthine, D., LEBEAU, A., & Gennigens, C. (2024). EV285/#587  Neoadjuvant versus adjuvant chemotherapy in high-grade epithelial ovarian cancer: a retrospective study. International Journal of Gynecological Cancer, 231.3-A232. doi:10.1136/ijgc-2024-igcs.404

LEBEAU, A., Lenom, M., LAPAILLE, L., Gonne, E., PIRON, M., Goffin, F., Kakkos, A., Schoenen, S., Delbecque, K., PLEYERS, C., Seidel, L., Lovinfosse, P., Danthine, D., Kridelka, F., & Gennigens, C. (2024). EV286/#550  Hormone receptors expression in high-grade epithelial ovarian cancers: a retrospective study. International Journal of Gynecological Cancer, 232.1-A232. doi:10.1136/ijgc-2024-igcs.405

Gennigens, C., & LEBEAU, A. (05 September 2024). Highlights in gynaecological cancers. Belgian Journal of Medical Oncology, 18.
Peer Reviewed verified by ORBi

Salmon, A.* , LEBEAU, A.* , Streel, S., Dheur, A., Schoenen, S., Goffin, F., Gonne, E., Kridelka, F., Kakkos, A.* , & Gennigens, C.*. (22 June 2024). Locally advanced and metastatic endometrial cancer: Current and emerging therapies. Cancer Treatment Reviews, 129, 102790. doi:10.1016/j.ctrv.2024.102790
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pirson, S., Gautier, M., Baudin, L., Rouaud, L., Vanwynsberghe, A., Deroye, J., Bekisz, S., Gucciardo, F., Lebeau, A., Staumont, B., Blacher, S., Gilles, C., & Noël, A. (05 March 2024). AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated PI3K/AKT pathway [Poster presentation]. Gordon Research Conference and Seminar on Lymphatics, Ventura, United States - California.

Pirson, S., Gautier, M., Baudin, L., Rouaud, L., Vanwynsberghe, A., Deroye, J., Bekisz, S., Gucciardo, F., Lebeau, A., Staumont, B., Blacher, S., Gilles, C., & Noël, A. (14 June 2023). Identification of a new actor involved in lymphangiogenesis processes [Poster presentation]. Lymphatic Forum 2023, Banff, Canada.

Schmitz, L., Pirotte, M., Lebeau, A., Ernst, M., Fillet, M., DEVEY, A., SCHMITT, J., Cobraiville, G., BINSFELD, M., Gofflot, S., Beguin, Y.* , & Vertenoeil, G.*. (2023). Alterations of erythropoiesis in Covid-19 patients: prevalence of positive Coombs tests and iron metabolism. Therapeutic Advances in Hematology, 14, 20406207231199837. doi:10.1177/20406207231199837
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Bruyere, D., RONCARATI, P., Lebeau, A., Lerho, T., Poulain, F., Hendrick, E., Pilard, C., Reynders, C., Ancion, M., Luyckx, M., Renard, M., Jacob, Y., Twizere, J.-C., Peiffer, R., Peulen, O., Delvenne, P., Hubert, P., McBride, A., Gillet, N., ... Herfs, M. (2023). Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair. Theranostics, 13 (3), 1130 - 1149. doi:10.7150/thno.78091
Peer Reviewed verified by ORBi

Pirson, S., Gautier, M., Deroye, J., Blacher, S., Lebeau, A., Gucciardo, F., Baudin, L., Rouaud, L., Gilles, C., & Noël, A. (10 November 2022). Identification of a new partner of uPARAP/Endo180 involved in lymphangiogenesis processes [Poster presentation]. Imagine all the Vessels.

Gucciardo, F., Lebeau, A., Pirson, S., Blacher, S., Gautier, M., & Noël, A. (01 November 2022). Mechanistical investigation of the lymphatic morphogenesis during lymphedema [Poster presentation]. Gordon Research Conference, Barga, Italy.

Buntinx, F.* , Lebeau, A.* , Gillot, L., Baudin, L., Ndong Penda, R., Morfoisse, F., LALLEMAND, F., Vottero, G., NIZET, C., Nizet, J.-L., Blacher, S., & Noël, A. (18 October 2022). Single and combined impacts of irradiation and surgery on lymphatic vasculature and fibrosis associated to secondary lymphedema. Frontiers in Pharmacology, 13. doi:10.3389/fphar.2022.1016138
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pirson, S., Gautier, M., Deroye, J., Lebeau, A., Gucciardo, F., Baudin, L., Rouaud, L., Gilles, C., & Noël, A. (30 September 2022). Identification of a new partner of uPARAP/Endo180 involved in lymphangiogenesis processes [Poster presentation]. BACR, Gand, Belgium.

Pirson, S., Gautier, M., Deroye, J., Lebeau, A., Gucciardo, F., Baudin, L., Rouaud, L., & Noël, A. (06 September 2022). Identification of a new partner of uPARAP/Endo180 involved in lymphangiogenesis processes [Poster presentation]. Giga Day, Liège, Belgium.

Gillot, L., Lebeau, A., Baudin, L., POTTIER, C., Louis, T., Durré, T., Longuespée, R., Mazzucchelli, G., NIZET, C., BLACHER, S., KRIDELKA, F., & Noël, A. (14 May 2022). Periostin in lymph node pre-metastatic niches governs lymphatic endothelial cell functions and metastatic colonization. Cellular and Molecular Life Sciences, 79 (6), 295. doi:10.1007/s00018-022-04262-w
Peer Reviewed verified by ORBi

Gucciardo, F.* , Pirson, S.* , Baudin, L., Lebeau, A., & Noël, A. (22 April 2022). uPARAP/Endo180: a multifaceted protein of mesenchymal cells. Cellular and Molecular Life Sciences, 79 (5), 255. doi:10.1007/s00018-022-04249-7
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Gucciardo, F., Pirson, S., Lebeau, A., BLACHER, S., & Noël, A. (08 April 2022). Mechanistic investigation of the lymphatic morphogenesis during cancer progression [Poster presentation]. Télévie Seminar, Liège, Belgium.

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pirson, S., Gautier, M., Lebeau, A., Gucciardo, F., & Noël, A. (14 December 2021). Identification of a new partner of uPARAP/Endo180 involved in migration of lymphatic endothelial cells [Poster presentation]. Giga-Cancer Day.

Gucciardo, F., Pirson, S., Lebeau, A., BLACHER, S., & Noël, A. (17 November 2021). Mechanistic investigation of the lymphatic morphogenesis during cancer progression [Poster presentation]. 9ème congrès de la Société Francaise d'Angiogenèse, Nantes, France.

Wuidar, V., Gillot, L., Dias Da Silva, I., Lebeau, A., Gallez, A., & Pequeux, C. (2021). Sex-based differences in the tumor microenvironment. In Tumor Microenvironment - Novel Concepts. Springer Nature. doi:10.1007/978-3-030-73119-9_23
Peer reviewed

Hubert, P., RONCARATI, P., Demoulin, S., Pilard, C., Ancion, M., Reynders, C., Lerho, T., Bruyère, D., Lebeau, A., Radermecker, C., Meunier, M., Nokin, M.-J., Hendrick, E., Peulen, O., Delvenne, P., & Herfs, M. (2021). Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy. Journal for ImmunoTherapy of Cancer, 9 ((3)), 001966. doi:10.1136/jitc-2020-001966
Peer Reviewed verified by ORBi

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (01 October 2020). P08.03 Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy. Journal for ImmunoTherapy of Cancer, 8 (Suppl 2), 50-A51. doi:10.1136/jitc-2020-ITOC7.99

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (07 February 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. BACR 2020, Jette, Belgium.

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (29 January 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Télévie Seminar 2020, Bruxelles, Belgium.

Lebeau, A. (2019). L'infection par HPV altère l'équilibre dynamique du microbiote vaginale par le biais d'une réduction d'expression des peptides antimicrobiens [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/248018

Lebeau, A. (03 October 2019). L’infection par HPV favorise la vaginose bactérienne par le biais d’une réduction d’expression des peptides antimicrobiens [Paper presentation]. 12e Journée de l'AFIPP, Malbuisson, France.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (21 May 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Immunology Day 2019, Liège, Belgium.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (01 February 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. BACR 2019, Anvers, Belgium.

Lebeau, A. (28 January 2019). HPV-related innate peptide inhibition promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Télévie Seminar 2019.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (28 January 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Télévie Seminar 2019, Gembloux, Belgium.

Song, S., Bruyère, D., Devins, K., Lebeau, A., Reyes, C., & Herfs, M. (2019). Cervical Carcinogenesis, Early Detection and Prevention. In Gynecologic and Obstetric Pathology, Volume 1 (pp. 279-291). Springer.
Peer reviewed

Lebeau, A. (27 September 2018). Infection par HPV et vaginose bactérienne : une association à bénéfice réciproque [Paper presentation]. 11e Journée de l'AFIPP, Obernai, France.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (13 September 2018). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. GIGA-Cancer Day 2018, Liège, Belgium.

Bruyère, D., Lebeau, A., RONCARATI, P., Hendrick, E., Masson, M., Twizere, J.-C., Pilard, C., Hubert, P., DELVENNE, P., & Herfs, M. (30 May 2018). Deciphering the radiosensitivity of HPV-positive tumors [Poster presentation]. 5th meeting on emerging issues in oncogenic virus research, San Pietro in Bevagna, Italy.

Bruyère, D., Lebeau, A., RONCARATI, P., Hendrick, E., Masson, M., Twizere, J.-C., Pilard, C., Hubert, P., DELVENNE, P., & Herfs, M. (28 May 2018). Deciphering the radiosensitivity of HPV-positive tumors [Poster presentation]. EDT-Immunology day 2018, Liège, Belgium.

Lebeau, A., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., TAZIAUX, S., Hubert, P., Delvenne, P., & Herfs, M. (28 May 2018). HPV-related innate peptide inhibition promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Immunology day 2018, Liège, Belgium.

Lebeau, A., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., TAZIAUX, S., Hubert, P., Delvenne, P., & Herfs, M. (01 February 2018). HPV-related innate peptide inhibition promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Annual Televie seminar, Bruxelles, Belgium.

Herfs, M., RONCARATI, P., KOOPMANSCH, B., Peulen, O., Bruyère, D., Lebeau, A., Hendrick, E., Hubert, P., PONCIN, A., Penny, W., Piazzon, N., Monnien, F., Guenat, D., Mougin, C., Prétet, J.-L., Vuitton, L., SEGERS, K., LAMBERT, F., BOURS, V., ... Delvenne, P. (2018). A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalized medicine. British Journal of Cancer, 118(10), 1302-1312. doi:10.1038/s41416-018-0049-2
Peer Reviewed verified by ORBi

Lebeau, A. (28 September 2017). Altered antimicrobial peptide expression in HPV-related (pre)neoplastic lesions [Paper presentation]. Xe Journées scientifiques de l'Association francophone des Infections par Papillomavirus et Polyomavirus, Sainte Foy les Lyon, France.

Lebeau, A., Bruyère, D., RONCARATI, P., DELVENNE, P., Hubert, P., & Herfs, M. (01 February 2017). HPV-mediated innate peptide down-regulation promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. GIGA Day 2017, Liège, Belgium.

Herfs, M., Longuespée, R., Quick, C., RONCARATI, P., Suarez-Carmona, M., Hubert, P., Lebeau, A., Bruyère, D., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Lai, K., Dunn, A., Obregon, F., Yang, E., De Pauw, E., Crum, C., & Delvenne, P. (2017). Proteomic signatures reveal a dualistic and clinically relevant classification of anal canal carcinoma. Journal of Pathology, 241, 522-533. doi:10.1002/path.4858
Peer Reviewed verified by ORBi

Lebeau, A. (09 December 2016). HPV-mediated innate peptide down-regulation promotes the acquisition of bacterial/fungal infections within the genital tract [Paper presentation]. Séminaire GIGA Cancer, Liège, Belgium.

Lebeau, A., Bruyère, D., RONCARATI, P., Delvenne, P., Hubert, P., & Herfs, M. (08 December 2016). HPV-mediated innate peptide down-regulation promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Televie Seminar, Bruxelles, Belgium.

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