Profil

Hubert Pascale

Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques

GIGA Cancer - Experimental Pathology

See author's contact details
ORCID
0000-0002-0799-3047
Main Referenced Co-authors
Delvenne, Philippe  (124)
Herfs, Michael  (62)
Roncarati, Patrick  (50)
Evrard, Brigitte  (47)
Boniver, Jacques  (38)
Main Referenced Keywords
HPV (23); siRNA (13); Humans (9); Liposome (9); Langerhans cells (5);
Main Referenced Unit & Research Centers
Centre Interfacultaire de Recherche du Médicament - CIRM (17)
Giga-Cancer - ULiège [BE] (7)
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (6)
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège [BE] (2)
CRCE (1)
Main Referenced Disciplines
Oncology (83)
Pharmacy, pharmacology & toxicology (42)
Immunology & infectious disease (25)
Biochemistry, biophysics & molecular biology (11)
Reproductive medicine (gynecology, andrology, obstetrics) (7)

Publications (total 150)

The most downloaded
1415 downloads
Demoulin, S., RONCARATI, P., Delvenne, P., & Hubert, P. (2012). Production of large numbers of plasmacytoid dendritic cells with functional activities from CD34+ hematopoietic progenitor cells: use of IL-3. Experimental Hematology, 40 (4), 268-278. doi:10.1016/j.exphem.2012.01.002 https://hdl.handle.net/2268/111910

The most cited

150 citations (Scopus®)

Duray, A., Demoulin, S., Hubert, P., Delvenne, P., & Saussez, S. (2010). Immune suppression in head and neck cancers: a review. Clinical and Developmental Immunology, 2010, 701657. doi:10.1155/2010/701657 https://hdl.handle.net/2268/93561

Ancion, M., Luyckx, M., Renard, M., Reynders, C., Lerho, T., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., Herfs, M., & Hubert, P. (12 June 2023). Approach using "second generation" immune checkpoint inhibitors for the treatment of triple-negative breast cancer [Poster presentation]. EACR 2023, Turin, Italy.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Luyckx, M., Renard, M., Delvenne, P., Hubert, P., & Herfs, M. (02 February 2023). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV in carcinogenesis [Poster presentation]. Séminaire des chercheurs Télévie 2023.

Mohring, V., Hubert, P., Ancion, M., Nokin, M.-J., Roncarati, P., Agirman, F., Maloujahmoum, N., Lardinois, F., Wissocq, T., Herfs, M., Peulen, O., & Janji, B. (2023). Enhancement of anti-tumor immunity through interference with glycation stress in breast cancer [Poster presentation]. GIGA day.

Bruyere, D., RONCARATI, P., Lebeau, A., Lerho, T., Poulain, F., Hendrick, E., Pilard, C., Reynders, C., Ancion, M., Luyckx, M., Renard, M., Jacob, Y., Twizere, J.-C., Peiffer, R., Peulen, O., Delvenne, P., Hubert, P., McBride, A., Gillet, N., ... Herfs, M. (2023). Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair. Theranostics, 13 (3), 1130 - 1149. doi:10.7150/thno.78091
Peer Reviewed verified by ORBi

Reynders, C., Roncarati, P., Ancion, M., Lerho, T., Bruyère, D., Delvenne, P., Hubert, P., & Herfs, M. (29 September 2022). Caractérisations histopathologiques des cancers œsophagiennes et potentiel implication des infections par HPV de haut-risques [Paper presentation]. Conférence annuelle de l'Association Francophone pour l'étude des Infections à Papillomavirus et Polyomavirus 2022, France.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Pilard, C., Bruyère, D., Hendrick, E., Delvenne, P., Hubert, P., & Herfs, M. (09 September 2022). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV in carcinogenesis [Poster presentation]. INTERUNIVERSITY PHD STUDENT DAY.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Pilard, C., Hendrick, E., Bruyère, D., Delvenne, P., Hubert, P., & Herfs, M. (06 September 2022). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV infections in carcinogenesis [Poster presentation]. GIGA-Day 2022.

Mohring, V., Wissocq, T., Hubert, P., Herfs, M., Tiamiou, A., Hasmim Meriem, Nokin, M.-J., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (September 2022). Immunosuppressive effect of methylglyoxal stress in breast cancer [Paper presentation]. Annual meeting of the Belgian Association for Cancer Research, Belgium.

Mohring, V., Wissocq, T., Hubert, P., Herfs, M., Tiamiou, A., Hasmim, M., Nokin, M.-J., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (21 June 2022). Methylglyoxal reshapes breast tumor immune microenvironment [Poster presentation]. European association for cancer research congress 2022, Séville, Spain.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Bruyère, D., Hendrick, E., Pilard, C., Delvenne, P., Hubert, P., & Herfs, M. (29 April 2022). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV in carcinogenesis [Paper presentation]. Séminaire du GIGA-Cancer, Belgium.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Hendrick, E., Bruyère, D., Pilard, C., Delvenne, P., Hubert, P., & Herfs, M. (08 April 2022). Histopathological characterization of esophageal cancers and potential role of high-risk HPV infections [Poster presentation]. Séminaire des chercheurs Télévie 2022, Belgium.

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Mohring, V., Wissocq, T., Hubert, P., Herfs, M., Tiamiou, A., Hasmim Meriem, Nokin, M.-J., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (2022). Methylglyoxal regulates the recruitment of tumor-infiltrating immunosuppressive cells in breast cancer [Poster presentation]. PhD Day UNamur 2022, Belgium.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Pilard, C., Bruyère, D., Hendrick, E., Delvenne, P., Hubert, P., & Herfs, M. (14 December 2021). Histopathological characterization of esophageal cancers and potential role of high-risk HPV infections [Poster presentation]. Giga Cancer Day 2021.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Bruyère, D., Hendrick, E., Pilard, C., Hubert, P., Delvenne, P., & Herfs, M. (01 October 2021). Caractérisation histopathologique des cancers œsophagiens et potentiel rôle des HPV [Paper presentation]. Conférence annuelle de l'Association Francophone pour l'étude des Infections à Papillomavirus et Polyomavirus, France.

Wissocq, T., Hubert, P., Tiamiou, A., Hasmim, M., Nokin, M.-J., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (May 2021). Methylglyoxal, a byproduct of glycolysis, modulates breast cancer immune landscape [Poster presentation]. 4th METABOLISM & CANCER SYMPOSIUM VIRTUAL MEETING, Bordeaux, France.

Bruyère, D., Monnien, F., Colpart, P., RONCARATI, P., Vuitton, L., Hendrick, E., Lepinoy, A., Luquain, A., Pilard, C., Lerho, T., Molimard, C., Maingon, P., Arnould, L., Bone-Lepinoy, M.-C., Dusserre, L., Martin, L., Reynders, C., Ancion, M., Peiffert, D., ... Herfs, M. (2021). Treatment algorithm and prognostic factors for patients with stage I–III carcinoma of the anal canal: a 20-year multicenter study. Modern Pathology, 34, 116-130. doi:10.1038/s41379-020-0637-6
Peer Reviewed verified by ORBi

Pilard, C.* , Ancion, M.* , Delvenne, P., JERUSALEM, G., Hubert, P., & Herfs, M. (2021). Cancer immunotherapy: it’s time to better predict patients’ response. British Journal of Cancer, 125(7), 927-938. doi:10.1038/s41416-021-01413-x
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Hubert, P., RONCARATI, P., Demoulin, S., Pilard, C., Ancion, M., Reynders, C., Lerho, T., Bruyère, D., Lebeau, A., Radermecker, C., Meunier, M., Nokin, M.-J., Hendrick, E., Peulen, O., Delvenne, P., & Herfs, M. (2021). Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy. Journal for ImmunoTherapy of Cancer, 9 ((3)), 001966. doi:10.1136/jitc-2020-001966
Peer Reviewed verified by ORBi

Pilard, C., RONCARATI, P., Hendrick, E., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (03 November 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Paper presentation]. Cytokines 2020, Seattle (Virtual), United States.

LAMBERT, V.* , hansen, S.* , Schoumacher, M.* , Lecomte, J., Leenders, J., Hubert, P., Herfs, M., Blacher, S., Carnet, O., Yip, C., BLAISE, P., DUCHATEAU, E., LOCHT, B., THYS, M., CAVALIER, E., GOTHOT, A., Govaerts, B., RAKIC, J.-M., Noël, A.* , & De Tullio, P.*. (2020). Pyruvate dehydrogenase kinase/lactate axis: a therapeutic target for neovascular age-related macular degeneration identified by metabolomics. Journal of Molecular Medicine. doi:10.1007/s00109-020-01994-9
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pilard, C., RONCARATI, P., Hendrick, E., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (03 October 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. 7th Immunotherapy of Cancer Conference (ITOC7), Munich (Virtual), Germany.

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (01 October 2020). P08.03 Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy. Journal for ImmunoTherapy of Cancer, 8 (Suppl 2), 50-A51. doi:10.1136/jitc-2020-ITOC7.99

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (07 February 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. BACR 2020, Jette, Belgium.

Wissocq, T., Hubert, P., Caprasse, M., Nokin, M.-J., Noman, M. Z., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (07 February 2020). Methylglyoxal stress contributes to immunosuppression in breast cancer [Poster presentation]. Association Belge pour l'Etude du Cancer "A.B.E.C", Bruxelles, Belgium.

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (29 January 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Télévie Seminar 2020, Bruxelles, Belgium.

Staumont, B., Jamakhani, M., Costa, C., Vandermeers, F., Sriramareddy, S. N., Redouté, G., Mascaux, C., Delvenne, P., Hubert, P., Safari, R., & Willems, L. (2020). TGFα Promotes Chemoresistance of Malignant Pleural Mesothelioma. Cancers, 12 (6), 1484. doi:10.3390/cancers12061484
Peer Reviewed verified by ORBi

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (21 May 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Immunology Day 2019, Liège, Belgium.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (01 February 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. BACR 2019, Anvers, Belgium.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (28 January 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Télévie Seminar 2019, Gembloux, Belgium.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (13 September 2018). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. GIGA-Cancer Day 2018, Liège, Belgium.

Bruyère, D., Lebeau, A., RONCARATI, P., Hendrick, E., Masson, M., Twizere, J.-C., Pilard, C., Hubert, P., DELVENNE, P., & Herfs, M. (30 May 2018). Deciphering the radiosensitivity of HPV-positive tumors [Poster presentation]. 5th meeting on emerging issues in oncogenic virus research, San Pietro in Bevagna, Italy.

Bruyère, D., Lebeau, A., RONCARATI, P., Hendrick, E., Masson, M., Twizere, J.-C., Pilard, C., Hubert, P., DELVENNE, P., & Herfs, M. (28 May 2018). Deciphering the radiosensitivity of HPV-positive tumors [Poster presentation]. EDT-Immunology day 2018, Liège, Belgium.

Lebeau, A., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., TAZIAUX, S., Hubert, P., Delvenne, P., & Herfs, M. (28 May 2018). HPV-related innate peptide inhibition promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Immunology day 2018, Liège, Belgium.

Lebeau, A., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., TAZIAUX, S., Hubert, P., Delvenne, P., & Herfs, M. (01 February 2018). HPV-related innate peptide inhibition promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Annual Televie seminar, Bruxelles, Belgium.

Collignon, E.* , Canale, A.* , Al Wardi, C., Bizet, M., Calonne, E., Dedeurwaerder, S., Garaud, S., Naveaux, C., Barham, W., Wilson, A., Bouchat, S., Hubert, P., Van Lint, C., Yull, F., Sotiriou, C., Willard-Gallo, K., Noël, A.* , & Fuks, F.*. (2018). Immunity drives TET1 regulation in cancer through NF-kappaB. Science Advances, 4 (6), 7309. doi:10.1126/sciadv.aap7309
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Herfs, M., RONCARATI, P., KOOPMANSCH, B., Peulen, O., Bruyère, D., Lebeau, A., Hendrick, E., Hubert, P., PONCIN, A., Penny, W., Piazzon, N., Monnien, F., Guenat, D., Mougin, C., Prétet, J.-L., Vuitton, L., SEGERS, K., LAMBERT, F., BOURS, V., ... Delvenne, P. (2018). A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalized medicine. British Journal of Cancer, 118(10), 1302-1312. doi:10.1038/s41416-018-0049-2
Peer Reviewed verified by ORBi

Lechanteur, A., Furst, T., Delvenne, P., Evrard, B., Hubert, P., & Piel, G. (07 December 2017). Promoting vaginal distribution of two active siRNA-complexed in liposomes for cervical cancer treatment [Paper presentation]. SF Nano Annual Meeting 2017, Bordeaux, France.

Lechanteur, A., Furst, T., Delvenne, P., Evrard, B., Hubert, P., & Piel, G. (05 December 2017). Promoting vaginal distribution of two active siRNA-complexed in liposomes for cervical cancer treatment [Paper presentation]. 4th SF Nano Annual Meeting, Bordeaux, France.

Lechanteur, A., Furst Tania, Evrard, B., Delvenne, P., Hubert, P., & Piel, G. (25 April 2017). Promoting vaginal distribution of two active siRNA-complexed in liposomes for cervical cancer treatment [Paper presentation]. 1st SPLC-Controlled Release Society, Santiago de Compostela, Spain.

Lechanteur, A., Furst, T., Delvenne, P., Evrard, B., Hubert, P., & Piel, G. (04 April 2017). Promoting vaginal distribution of two active siRNA-complexed in liposomes for cervical cancer treatment [Paper presentation]. 2nd European Conference on Pharmaceutics: Drug Delivery, Krakow, Poland.

Lechanteur, A., Furst, T., Delvenne, P., Evrard, B., Piel, G., & Hubert, P. (2017). Promoting vaginal distribution of E7 and MCL-1 siRNA-silencing nanoparticles for cervical cancer treatment. Molecular Pharmaceutics. doi:10.1021/acs.molpharmaceut.6b01154
Peer Reviewed verified by ORBi

Lebeau, A., Bruyère, D., RONCARATI, P., DELVENNE, P., Hubert, P., & Herfs, M. (01 February 2017). HPV-mediated innate peptide down-regulation promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. GIGA Day 2017, Liège, Belgium.

Staumont, B., Costa, C., Vandermeers, F., Neelature Sriramareddy, S., Mascaux, C., Scherpereel, A., DUYSINX, B., LOUIS, R., DELVENNE, P., Hubert, P., & Willems, L. (01 February 2017). EGFR tyrosine kinase inhibitors overcome resistance to chemotherapy in malignant pleural mesothelioma [Poster presentation]. GIGA conference day: New insights into the hallmarks of cancer.

Herfs, M., Longuespée, R., Quick, C., RONCARATI, P., Suarez-Carmona, M., Hubert, P., Lebeau, A., Bruyère, D., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Lai, K., Dunn, A., Obregon, F., Yang, E., De Pauw, E., Crum, C., & Delvenne, P. (2017). Proteomic signatures reveal a dualistic and clinically relevant classification of anal canal carcinoma. Journal of Pathology, 241, 522-533. doi:10.1002/path.4858
Peer Reviewed verified by ORBi

Lebeau, A., Bruyère, D., RONCARATI, P., Delvenne, P., Hubert, P., & Herfs, M. (08 December 2016). HPV-mediated innate peptide down-regulation promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Televie Seminar, Bruxelles, Belgium.

Lechanteur, A., Furst, T., Evrard, B., DELVENNE, P., Hubert, P., & Piel, G. (27 September 2016). FINDING THE RIGHT BALANCE BETWEEN EFFECTIVENESS, TOXICITY AND VAGINAL DIFFUSION OF siRNA LIPOPLEXES FOR CERVICAL CANCER TREATMENT [Poster presentation]. 4th Conference on Innovation in Drug Delivery: Site specific drug delivery, Antibes, France.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Hubert, P., & Piel, G. (August 2016). PEGylation of lipoplexes: The right balance between cytotoxicity and siRNA effectiveness. European Journal of Pharmaceutical Sciences, 93, 493-593. doi:10.1016/j.ejps.2016.08.058
Peer Reviewed verified by ORBi

Staumont, B., Costa, C., Vandermeers, F., Neelature Sriramareddy, S., Mascaux, C., Scherpereel, A., DUYSINX, B., LOUIS, R., DELVENNE, P., Hubert, P., & Willems, L. (2016). EGFR tyrosine kinase inhibitors overcome resistance to chemotherapy in malignant pleural mesothelioma. In Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016.
Peer reviewed

Hubaux, R., Vandermeers, F., Cosse, J.-P., Crisanti, C., Kapoor, V., Albelda, S. M., Mascaux, C., Delvenne, P., Hubert, P., & Willems, L. (19 October 2015). Valproic acid improves second-line regimen of small cell lung carcinoma in preclinical models. ERJ Open Research, 1 (2), 00028. doi:10.1183/23120541.00028-2015
Peer Reviewed verified by ORBi

Lechanteur, A., Furst, T., Delvenne, P., Evrard, B., Hubert, P., & Piel, G. (28 May 2015). DEVELOPMENT OF LIPOPLEXES FOR A TOPICAL TREATMENT OF HPV16 INDUCED LESIONS: In vitro and ex vivo studies [Paper presentation]. 18th Forum of Pharmaceutical Sciences, Blankenberg, Belgium.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (13 May 2015). Anti-E6/E7/MCL1 pegylated lipoplexes for a topical treatment of HPV16 induced lesions [Paper presentation]. GIGA-Cancer Day 2015, Liege, Belgium.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (14 April 2015). Anti-E6/E7/MCL1 pegylated lipoplexes for a vaginal treatment of cervical cancer [Paper presentation]. 1st European Conference on Pharmaceutics Drug Delivery, Reims, France.

Lechanteur, A.* , Furst, T.* , Evrard, B., Delvenne, P., Hubert, P., & Piel, G. (16 February 2015). Development of anti-E6 pegylated lipoplexes for mucosal application in the context of cervical preneoplastic lesions. International Journal of Pharmaceutics, 483, 268-277. doi:10.1016/j.ijpharm.2015.02.041
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (11 February 2015). Anti-E6/E7/MCL1 pegylated lipoplexes for a topical treatment of cervical (pre)neoplastic lesions [Poster presentation]. Séminaire des chercheurs Télévie 2015, Bruxelles, Belgium.

Lechanteur, A., Furst, T., Delvenne, P., Evrard, B., Hubert, P., & Piel, G. (2015). Anti-E6/E7/MCL-1 pegylated lipoplexes for a vaginal treatment of cervical cancer [Paper presentation]. 1st European Conference on Pharmaceutics: Drug Delivery, Reims, France.

Suarez-Carmona, M., Bourcy, M., LESAGE, J., Leroi, N., Syne, L., Blacher, S., Hubert, P., Erpicum, C., Foidart, J.-M., Delvenne, P., Birembaut, P., Noël, A., Polette, M., & Gilles, C. (2015). Soluble factors regulated by epithelial-mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment. Journal of Pathology, 236 (4), 491-504. doi:10.1002/path.4546
Peer Reviewed verified by ORBi

Shiva Shankar, T. V., Sulka, B., Hubert, P., Hubaux, R., Delvenne, P., Pendeville-Samain, H., Boittiaux, I., Lambert, D. M., Wouters, J., Maillard, C., Blacher, S., Noël, A., Struman, I., & Willems, L. (2015). N-Hydroxy-6-(5-Nitro- Naphtalimide)-Hexanamide Inhibits Lysine Deacetylation, Mitigates Angiogenesis and Reduces Tumor Growth. Journal of Cancer Sciences, 2 (2), 0-11.
Peer reviewed

Suarez-Carmona, M., Hubert, P., Delvenne, P., & Herfs, M. (2015). Defensins: « simple » antimicrobial peptides or broad-spectrum molecules ? Cytokine and Growth Factor Reviews, 26, 361-370. doi:10.1016/j.cytogfr.2014.12.005
Peer Reviewed verified by ORBi

Demoulin, S., Herfs, M., SOMJA, J., RONCARATI, P., Delvenne, P., & Hubert, P. (2015). HMGB1 secretion during cervical carcinogenesis promotes the acquisition of a tolerogenic functionality by plasmacytoid dendritic cells. International Journal of Cancer, 137, 345-358. doi:10.1002/ijc.29389
Peer Reviewed verified by ORBi

Mirkovic, J., Howitt, B., RONCARATI, P., Demoulin, S., Suarez-Carmona, M., Hubert, P., Mckeon, F., Xian, W., Delvenne, P., Crum, C. P., & Herfs, M. (2015). Carcinogenic HPV infection in the cervical squamo-columnar junction. Journal of Pathology, 236, 265-271. doi:10.1002/path.4533
Peer Reviewed verified by ORBi

Demoulin, S., SOMJA, J., duray, A., guenin, S., RONCARATI, P., DELVENNE, P., Herfs, M.* , & Hubert, P.*. (2015). Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion. Oncoimmunology, 6. doi:10.1080/2162402X.2015.1008334
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Herfs, M., SOMJA, J., Howitt, B. E., Suarez-Carmona, M., KUSTERMANS, G., Hubert, P., DOYEN, J., GOFFIN, F., Kridelka, F., Crum, C. P., & Delvenne, P. (2015). Unique recurrence patterns of cervical intraepithelial neoplasia following excision of the squamo-columnar junction. International Journal of Cancer, 136, 1043-1052. doi:10.1002/ijc.28978
Peer Reviewed verified by ORBi

Furst, T., Lechanteur, A., Hubert, P., Evrard, B., & Piel, G. (03 November 2014). DEVELOPMENT AND CHARACTERIZATION OF PEGYLATED LIPOPLEXES TO BE ENTRAPPED IN HEC SPONGES FOR VAGINAL DELIVERY [Poster presentation]. 2014 AAPS Annual Meeting and Exposition, San Diego, United States.

Furst, T., Lechanteur, A., Hubert, P., Evrard, B., & Piel, G. (20 October 2014). DEVELOPMENT AND CHARACTERIZATION OF PEGYLATED LIPOPLEXES TO BE ENTRAPPED IN HEC SPONGES FOR VAGINAL DELIVERY [Poster presentation]. 3rd NanoFar Autumn School, Louvain, Belgium.

Lechanteur, A., Furst, T., Kanber, E., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (04 October 2014). Development and optimization of pegylated lipoplexes for vaginal application [Paper presentation]. SFNano Workshop 2014, Porto, Portugal.

Furst, T., Lechanteur, A., Hubert, P., Evrard, B., & Piel, G. (27 August 2014). DEVELOPMENT OF PEG-COATED LIPOPLEXES TO BE INCORPORATED INTO MUCOADHESIVE HEC-SPONGES [Poster presentation]. Translational Nanomedicine, International Meeting, Angers, France.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (19 May 2014). ASSOCIATION OF LIPOSOMES AND siRNA FOR A LOCAL TREATMENT OF CERVICAL CANCER [Poster presentation]. GIGA-Cancer Day 2014.

Furst, T., Lechanteur, A., Hubert, P., Evrard, B., & Piel, G. (03 April 2014). DEVELOPMENT OF PEG-COATED LIPOPLEXES WITH siRNA ANTI E6/E7 ONCOPROTEINS FOR THE TREATMENT OF HPV CANCERS [Poster presentation]. 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal.

Furst, T., Lechanteur, A., Hubert, P., Evrard, B., & Piel, G. (16 February 2014). Development of PEG-coated lipoplexes with siRNA anti-E6/E7 oncoproteins to be incorporated into mucoadhesive HEC-sponges for the treatment of HPV cancers [Poster presentation]. 10th International Conference and Workshop on Biological Barriers, Saarbrucken, Germany.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (16 February 2014). Development of anti-HPV lipoplexes formulations for the treatment of cervical cancer [Poster presentation]. 10th International conference and workshop on Biological Barriers.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (27 January 2014). Development of anti-HPV lipoplexes formulations for the treatment of cervical cancer [Poster presentation]. GIGA-Day 2014.

Hubert, P.* , Herman, L.* , RONCARATI, P., Maillard, C., Renoux, V., Demoulin, S., Erpicum, C., Foidart, J.-M., Boniver, J., Noël, A., Delvenne, P., & Herfs, M. (2014). Altered alpha-defensin 5 expression in cervical squamocolumnar junction: implication in the formation of a viral/tumour-permissive microenvironment. Journal of Pathology, 234 (4), 464-77. doi:10.1002/path.4435
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Suarez-Carmona, M., Hubert, P., Gonzalez, A., Duray, A., RONCARATI, P., Erpicum, C., Boniver, J., Castronovo, V., Noël, A., Saussez, S., Peulen, O., Delvenne, P., & Herfs, M. (2014). DeltaNp63 isoform-mediated beta-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma. Oncotarget, 5 (7), 1856-1868. doi:10.18632/oncotarget.1819
Peer Reviewed verified by ORBi

Shostak, K., Zhang, X., Hubert, P., Göktuna, S., Jiang, Z., Klevernic, I., Hildebrand, J., Roncarati, P., Hennuy, B., Ladang, A., SOMJA, J., Gothot, A., Close, P., Delvenne, P., & Chariot, A. (2014). NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling. Nature Communications, 5, 5232. doi:10.1038/ncomms6232
Peer Reviewed verified by ORBi

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., RONCARATI, P., Piel, G., & Hubert, P. (05 December 2013). Development of anti-HPV lipoplexes formulations for the treatment of cervical cancer [Poster presentation]. Séminaire des chercheurs du Télévie 2014.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (03 December 2013). Development of anti-HPV lipoplexes for the treatment of cervical cancer [Paper presentation]. 28ième Journées Scientifiques du GTRV, Angers, France.

Furst, T., Lechanteur, A., Hubert, P., Evrard, B., & Piel, G. (02 December 2013). Development of peggylated lipoplexes with siRNA anti-E6/E7 oncoproteins for the treatment og cancers induced by HPV [Poster presentation]. GTRV, Orléans, France.

Demoulin, S., Somja, J., Herfs, M., RONCARATI, P., Delvenne, P., & Hubert, P. (December 2013). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. 4th International Workshop on plasmacytoid dendritic cells, Paris, France.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (17 October 2013). Development of anti-HPV lipoplexes for the treatment of cervical cancer [Paper presentation]. Dix-septième forum des sciences pharmaceutiques.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Piel, G., & Hubert, P. (17 June 2013). Développement et optimisation de vecteur de type lipoplexe pour une approche thérapeutique antisens dans le cadre de lésions induites par HPV [Paper presentation]. Séminaire C.I.R.M.

Renauld, J., Johnen, N., Hubert, P., Thelen, N., Cloes, M., & Thiry, M. (28 January 2013). Whole organ culture in rotating bioreactor: the rat embryonic inner ear [Poster presentation]. GIGA-Day, Liège, Belgium.

Guenin, S., Mouallif, M., Hubert, P., Jacobs, N., Krusy, N., Duray, A., Ennaji, M. M., Saussez, S., & Delvenne, P. (2013). Interleukin-32 expression is associated with a poorer prognosis in head and neck squamous cell carcinoma. Molecular Carcinogenesis, 53 (8), 667-673. doi:10.1002/mc.21996
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Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., RONCARATI, P., Piel, G., & Hubert, P. (2013). Development of anti-HPV lipoplexes for the treatment of cervical cancer [Poster presentation]. Cancer GIGA-Day 2013, liège, Belgium.

Reschner, A., BONTEMS, S., Le Gac, S., Lambermont, J., De Francq, E., Hubert, P., Moucheron, C., Kirsch-De Mesmaeker, A., Raes, M., Piette, J., & Delvenne, P. (2013). Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53. Gene Therapy, 20 (4), 435-443. doi:10.1038/gt.2012.54
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Somja, J., Demoulin, S., RONCARATI, P., Herfs, M., BLETARD, N., Delvenne, P., & Hubert, P. (2013). Dendritic cells in Barrett's esophagus carcinogenesis: an inadequate microenvironment for antitumor immunity? American Journal of Pathology, 182, 2168-2179. doi:10.1016/j.ajpath.2013.02.036
Peer Reviewed verified by ORBi

Demoulin, S., Herfs, M., Delvenne, P., & Hubert, P. (2013). Tumor microenvironment converts plasmacytoid dendritic cells into immunosuppressive/tolerogenic cells: insight into the molecular mechanisms. Journal of Leukocyte Biology, 93 (3), 343-352. doi:10.1189/jlb.0812397
Peer Reviewed verified by ORBi

Lechanteur, A., Evrard, B., Delvenne, P., RONCARATI, P., Hubert, P., & Piel, G. (November 2012). Development and optimization of lipoplex vectors for an antisens therapeutic approach in the context of HPV induced lesions [Poster presentation]. Ecole doctorale en cancérologie expérimentale, liège, Belgium.

Furst, T., Lechanteur, A., Evrard, B., Delvenne, P., Hubert, P., Piette, M., & Piel, G. (22 October 2012). Development of a topical formulation containing lipoplexes able to inhibit E6 and E7 genes for the treatment of cervix cancer caused by HPV16 and HPV18 [Poster presentation]. NanoFar 1st Autumn School, Angers, France.

Lechanteur, A., Furst, T., Evrard, B., Delvenne, P., Hubert, P., & Piel, G. (22 October 2012). Development of a topical formulation containing lipoplexes able to inhibit E6 and E7 genes for the treatment of cervix cancer caused by HPV16 and HPV18 [Poster presentation]. NanoFar Automn School, Angers, France.

Costa, C., Vandermeers, F., Reddy, N. S., Mascaux, C., Scherpereel, A., Delvenne, P., Hubert, P., & Willems, L. (13 September 2012). The role of TGF-alpha in the resistance to mesothelioma chemotherapy [Poster presentation]. 11th International Conference of the International Mesothelioma Interest Group (iMig 2012), Boston, United States - Massachusetts.

Costa, C., Vandermeers, F., Reddy, N. S., Hubert, P., & Willems, L. (2012). The role of TGF-alpha in resistance to mesothelioma chemotherapy.

Herfs, M., Hubert, P., POIRRIER, A.-L., Vandevenne, Renoux, V., Habraken, Y., Cataldo, D., Boniver, J., & Delvenne, P. (2012). Proinflammatory Cytokines Induce Bronchial Hyperplasia and Squamous Metaplasia in Smokers: Implications for chronic obstructive pulmonary disease therapy. American Journal of Respiratory Cell and Molecular Biology, 47 (1), 67-79. doi:10.1165/rcmb.2011-0353OC
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Demoulin, S., RONCARATI, P., Delvenne, P., & Hubert, P. (2012). Production of large numbers of plasmacytoid dendritic cells with functional activities from CD34+ hematopoietic progenitor cells: use of IL-3. Experimental Hematology, 40 (4), 268-278. doi:10.1016/j.exphem.2012.01.002
Peer reviewed

Demoulin, S., RONCARATI, P., Delvenne, P., & Hubert, P. (December 2011). Production of large numbers of plasmacytoid dendritic cells with functional activities from CD34+ hematopoietic progenitor cells: use of IL-3 [Poster presentation]. 3ème Atelier International "Cellules Dendritiques Plasmacytoïdes et Réponses Immunes", Paris, France.

Costa, C., Vandermeers, F., Reddy, N. S., Mascaux, C., Hubert, P., Delvenne, P., & Willems, L. (2011). Thérapie du mésothéliome pleural : compréhension des mécanismes de résistance à la chimiothérapie.

Gillet, A., Lecomte, F., Hubert, P., Compère, P., Evrard, B., & Piel, G. (14 June 2011). Topical application of liposomes: parameters influencing their effectiveness [Poster presentation]. PharmSciFair, Prague, Czechia.

Gillet, A., Compère, P., Lecomte, F., Hubert, P., Ducat, E., Evrard, B., & Piel, G. (June 2011). Liposome surface charge influence on skin penetration behaviour. International Journal of Pharmaceutics, 411 (1-2), 223-231. doi:10.1016/j.ijpharm.2011.03.049
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Jost, M., Frankenne, F., Maillard, C., Hubert, P., Herman, L., Delvenne, P., Piette, M., Coia, I., Evrard, B., Lecomte, F., Hubert, P., Englert, Y., Bossens, M., van Pachterbeke, C., GOFFIN, F., Doyen, J., Kridelka, F., Snoeck, R., & FOIDART, J.-M. (20 May 2011). From the Clinics to the Bench and back to the Clinics: design of a medical treatment for Cervical Intraepithelial Neoplasia (CIN) [Paper presentation]. GIGA-Cancer Day, Liège, Belgium.

Gillet, A., Lecomte, F., Hubert, P., Compère, P., Evrard, B., & Piel, G. (12 May 2011). Parameters influencing the skin penetration effectiveness of liposomes [Paper presentation]. 15th Forum of Pharmaceutical Sciences, Spa, Belgium.

Gillet, A., Lecomte, F., Hubert, P., Compère, P., Evrard, B., & Piel, G. (28 March 2011). Evaluation of parameters affecting skin penetration behaviour of liposomes [Poster presentation]. Skin Forum 12th Annual Meeting, Frankfurt, Germany.

Herfs, M., Hubert, P., Moutschen, M., & Delvenne, P. (07 January 2011). Mucosal junctions: open doors to HPV and HIV infections? Trends in Microbiology, 19 (3), 114-120. doi:10.1016/j.tim.2010.12.006
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Demoulin, S., Herfs, M., Somja, J., Delvenne, P., Hubert, P., & RONCARATI, P. (2011). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. miRNA symposium, Namur, Belgium.

Demoulin, S., Somja, J., Herfs, M., Delvenne, P., & Hubert, P. (2011). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. GIGA Cancer Day, Liège, Belgium.

Gillet, A., Lecomte, F., Hubert, P., Ducat, E., Evrard, B., & Piel, G. (2011). Skin penetration behaviour of liposomes as a function of their composition. European Journal of Pharmaceutics and Biopharmaceutics, 79, 43-53. doi:10.1016/j.ejpb.2011.01.011
Peer Reviewed verified by ORBi

Gillet, A., Lecomte, F., Hubert, P., Evrard, B., & Piel, G. (October 2010). Interest of vesicular systems in dermal drug delivery [Poster presentation]. 2nd Innovation in Drug Delivery, Aix-en-Provence, France.

Demoulin, S., Herfs, M., Somja, J., RONCARATI, P., Boniver, J., Delvenne, P., & Hubert, P. (September 2010). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. Cell Symposium on Inflammation and Disease, Lisbonne, Portugal.

Gillet, A., Lecomte, F., Hubert, P., Evrard, B., & Piel, G. (06 July 2010). Penetration mechanism of classical and deformable liposomes through pig ear skin [Poster presentation]. Skin Forum 11th Annual Meeting, Edinburgh, United Kingdom.

Herman, L., Hubert, P., Herfs, M., Kustermans, G., Henrotin, Y., Bousarghin, L., Boniver, J., & Delvenne, P. (2010). The L1 major capsid protein of HPV16 differentially modulates APC trafficking according to the vaccination or natural infection context. European Journal of Immunology, 40 (11), 3075-84. doi:10.1002/eji.201040571
Peer Reviewed verified by ORBi

Demoulin, S., Somja, J., Herfs, M., Delvenne, P., & Hubert, P. (2010). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. GIGA Cancer Day, Liège, Belgium.

Mignon, B., Hubert, P., Defaweux, V., Cambier, L., Baldo, A., Mathy, A., & Tabart, J. (2010). Cytokinic response and MHC class II expression in feline dendritic cells exposed to Microsporum canis components [Paper presentation]. 24th Congress of the European Society of Veterinary Dermatology - European College of Veterinary Dermatology (ESVD-ECVD), Firenze, Italy.

Hubert, P., Doyen, J., Capelle, X., Arafa, M., Renoux, V., Bisig, B., Seidel, L., Evrard, B., Bousarghin, L., Gerday, C., Boniver, J., Foidart, J.-M., Delvenne, P., & Jacobs, N. (2010). Local applications of GM-CSF induce the recruitment of immune cells in cervical low-grade squamous intraepithelial lesions. American Journal of Reproductive Immunology, 64 (2), 126-136. doi:10.1111/j.1600-0897.2010.00834.x
Peer Reviewed verified by ORBi

Herfs, M., Hubert, P., Suarez-Carmona, M., Reschner, A., Saussez, S., Berx, G., Savagner, P., Boniver, J., & Delvenne, P. (2010). Regulation of p63 Isoforms by Snail and Slug Transcription Factors in Human Squamous Cell Carcinoma. American Journal of Pathology, 176 (4), 1941-1949. doi:10.2353/ajpath.2010.090804
Peer Reviewed verified by ORBi

Duray, A., Demoulin, S., Hubert, P., Delvenne, P., & Saussez, S. (2010). Immune suppression in head and neck cancers: a review. Clinical and Developmental Immunology, 2010, 701657. doi:10.1155/2010/701657
Peer Reviewed verified by ORBi

Herfs, M., Hubert, P., & Delvenne, P. (June 2009). Epithelial metaplasia: adult stem cell reprogramming and (pre)neoplastic transformation mediated by inflammation? Trends in Molecular Medicine, 15 (6), 245-253. doi:10.1016/j.molmed.2009.04.002
Peer Reviewed verified by ORBi

Herfs, M., Herman, L., Hubert, P., Minner, F., Arafa, M. M. M., Roncarati, P., Henrotin, Y., Boniver, J., & Delvenne, P. (April 2009). High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells. Cancer Immunology, Immunotherapy, 58 (4), 603-614. doi:10.1007/s00262-008-0584-4
Peer Reviewed verified by ORBi

Cloosen, S., Caberg, J.-H., Huls, M. B., Vanderlocht, J., Senden-Gilsbers, B. L. M. G., Roncarati, P., Hubert, P., Delvenne, P., Germeraad, W. T. V., & Bos, G. M. J. (February 2009). Surface Mucin-1 does not play a role in dendritic cell migration. Molecular Immunology, 46 (4), 738-742. doi:10.1016/j.molimm.2008.07.033
Peer Reviewed verified by ORBi

Caberg, J.-H., Hubert, P., Herman, L., Herfs, M., Roncarati, P., Boniver, J., & Delvenne, P. (January 2009). Increased migration of Langerhans cells in response to HPV16 E6 and E7 oncogene silencing: role of CCL20. Cancer Immunology, Immunotherapy, 58 (1), 39-47. doi:10.1007/s00262-008-0522-5
Peer Reviewed verified by ORBi

Vandermeers, F., Hubert, P., Delvenne, P., Mascaux, C., Grigoriu, B., Burny, A., Scherpereel, A., & Willems, L. (2009). Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma. Clinical Cancer Research, 15 (8), 2818-28. doi:10.1158/1078-0432.CCR-08-1579
Peer Reviewed verified by ORBi

Noël, A., Herman, L., Hubert, P., Delvenne, P., Boniver, J., Evrard, B., Delattre, L., Frankenne, F., & Foidart, J.-M. (27 November 2008). MUCOADHESIVE PHARMACEUTICAL COMPOSITIONS COMPRISING CHEMOATTRACTANTS.

Caberg, J.-H., Hubert, P., Begon, D., Herfs, M., Roncarati, P., Boniver, J., & Delvenne, P. (July 2008). Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes. Carcinogenesis, 29 (7), 1441-7. doi:10.1093/carcin/bgn145
Peer Reviewed verified by ORBi

Herfs, M., Hubert, P., Kholod, N., Caberg, J.-H., Gilles, C., Berx, G., Savagner, P., Boniver, J., & Delvenne, P. (May 2008). Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression. American Journal of Pathology, 172 (5), 1391-402. doi:10.2353/ajpath.2008.071004
Peer Reviewed verified by ORBi

Quatresooz, P., Pierard, C., Paquet, P., Hubert, P., Delvenne, P., & Pierard, G. (2008). Crossroads between actinic keratosis and squamous cell carcinoma, and novel pharmacological issues. European Journal of Dermatology, 18 (1), 6-10. doi:10.1684/ejd.2008.0303
Peer Reviewed verified by ORBi

Reschner, A., Hubert, P., Delvenne, P., Boniver, J., & Jacobs, N. (2008). Innate lymphocyte and dendritic cell cross-talk: a key factor in the regulation of the immune response. Clinical and Experimental Immunology, 152 (2), 219-26. doi:10.1111/j.1365-2249.2008.03624.x
Peer Reviewed verified by ORBi

Hubert, P., Jacobs, N., Caberg, J.-H., Boniver, J., & Delvenne, P. (October 2007). The cross-talk between dendritic and regulatory T cells: good or evil? Journal of Leukocyte Biology, 82 (4), 781-94. doi:10.1189/jlb.1106694
Peer Reviewed verified by ORBi

Herman, L., Hubert, P., Caberg, J.-H., Evrard, B., Kedzia, W., Boniver, J., & Delvenne, P. (July 2007). MIP3 alpha stimulates the migration of Langerhans cells in models of human papillomavirus (HPV)-associated (pre)neoplastic epithelium. Cancer Immunology, Immunotherapy, 56 (7), 1087-1096. doi:10.1007/s00262-006-0255-2
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Delvenne, P., Goffin, F., Kridelka, F., Arafa, M., Carberg, J., Herfs, M., Herman, L., Hubert, P., Jacobs, N., Kholod, N., Foidart, J.-M., & Boniver, J. (2007). La cancer du col utérin: une infection par HPV qui tourne mal. Tempo Médical.

Delvenne, P., Herman, L., Kholod, N., Caberg, J.-H., Herfs, M., Boniver, J., Jacobs, N., & Hubert, P. (2007). Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix. Molecular and Cellular Endocrinology, 264 (1-2), 1-5. doi:10.1016/j.mce.2006.10.014
Peer Reviewed verified by ORBi

Hubert, P., Herman, L., Maillard, C., Caberg, J.-H., Nikkels, A., Pierard, G., Foidart, J.-M., Noël, A., Boniver, J., & Delvenne, P. (2007). Defensis induce the recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo. FASEB Journal, 21 (11), 2765-75. doi:10.1096/fj.06-7646com
Peer Reviewed verified by ORBi

Delvenne, P., Goffin, F., Kridelka, F., Arafa, M., Caberg, J.-H., Herfs, M., Herman, L., Hubert, P., Jacobs, N., Kholod, N., Boniver, J., & Foidart, J.-M. (2007). Le cancer du col de l'utérus: du virus au traitement. Revue Médicale de Liège, 62(S1), 2-6.

Hubert, P., Doyen, J., Chapelle, X., Evrard, B., Gerday, C., Boniver, J., Foidart, J.-M., & Jacobs, N. (2007). Phase I/IIclinical trial of local GM-CSF application in patients with cervical HPV-associated low grade squamous intraepithelial lesions [Paper presentation]. 24th International Papillomavirus Conference and Clinical Workshops, Bejing, China.

Jacobs, N., Boniver, J., Hubert, P., & Delvenne, P. (2007). Dendritic Cells: More Than Just Adaptive Immunity Inducers? Current Immunology Reviews, 2, 17-22. doi:10.2174/157339507779802214
Peer Reviewed verified by ORBi

Hubert, P., Evrard, B., Delattre, L., Boniver, J., Delvenne, P., Noël, A., Frankenne, F., & Foidart, J.-M. (12 December 2006). Mucoadhesive composition comprising polyacrylate and chemoattractant.

Herman, L., Hubert, P., Delvenne, P., Boniver, J., Evrard, B., Delattre, L., Frankenne, F., Noël, A., & Foidart, J.-M. (28 June 2006). MUCOADHESIVE PHARMACEUTICAL COMPOSITIONS COMPRISING CHEMOATTRACTANTS.

Hubert, P., Caberg, J.-H., Gilles, C., Bousarghin, L., Franzen-Detrooz, E., Boniver, J., & Delvenne, P. (July 2005). E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions. Journal of Pathology, 206 (3), 346-355. doi:10.1002/path.1771
Peer Reviewed verified by ORBi

Hubert, P., Bousarghin, L., Greimers, R., Franzen-Detrooz, E., Boniver, J., & Delvenne, P. (June 2005). Production of large numbers of Langerhans' cells with intraepithelial migration ability in vitro. Experimental Dermatology, 14 (6), 469-477. doi:10.1111/j.0906-6705.2005.00299.x
Peer Reviewed verified by ORBi

Bousarghin, L., Hubert, P., Franzen, E., Jacobs, N., Boniver, J., & Delvenne, P. (2005). Human papillomavirus 16 virus-like particles use heparan sulfates to bind dendritic cells and colocalize with langerin in Langerhans cells. Journal of General Virology, 86 (Pt 5), 1297-305. doi:10.1099/vir.0.80559-0
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Hallez, S., Simon, P., Maudoux, F., Doyen, J., Noël, J.-C., Beliard, A., Capelle, X., Buxant, F., Fayt, I., Lagrost, A.-C., Hubert, P., Gerday, C., Burny, A., Boniver, J., Foidart, J.-M., Delvenne, P., & Jacobs, N. (July 2004). Phase I/II trial of immunogenicity of a human papillomavirus (HPV) type 16 E7 protein-based vaccine in women with oncogenic HPV-positive cervical intraepithelial neoplasia. Cancer Immunology, Immunotherapy, 53 (7), 642-650. doi:10.1007/s00262-004-0501-4
Peer Reviewed verified by ORBi

Hubert, P., Evrard, B., Maillard, C., Franzen-Detrooz, E., Delattre, L., Foidart, J.-M., Noël, A., Boniver, J., & Delvenne, P. (2004). Delivery of granulocyte-macrophage colony-stimulating factor in bioadhesive hydrogel stimulates migration of dendritic cells in models human papillomavirus-associated (pre)neoplastic epithelial lesions. Antimicrobial Agents and Chemotherapy, 48 (11), 4342-4348. doi:10.1128/AAC.48.11.4342-4348.2004
Peer Reviewed verified by ORBi

Delvenne, P., Hubert, P., & Jacobs, N. (2004). Epithelial metaplasia: an inadequate environment for antitumour immunity? Trends in Immunology, 25 (4), 169-73. doi:10.1016/j.it.2004.02.002
Peer Reviewed verified by ORBi

Evrard, B., Hubert, P., Delvenne, P., Boniver, J., & Delattre, L. (2004). Development of a hydrogel containing GM-CSF to improve the dendritic cells colonisation of HPV+ epithelium. In Proceedings of Eur conference on drug delivery and pharmaceutical technology.
Peer reviewed

Delvenne, P., Hubert, P., Havard, L., Renard, I., Boniver, J., & Jacobs, N. (2003). Modèles expérimentaux in vitro des HPV. In F. Aubin, J. F. Pretet, ... C. Mougin, Papillomavirus Humains (pp. 75-101). Paris, France: Tec & Doc.

Jacobs, N., Renard, I., Al-Saleh, W., Hubert, P., Doyen, J., Kedzia, W., Boniver, J., & Delvenne, P. (2003). Distinct T cell subsets and cytokine production in cultures derived from transformation zone and squamous intraepithelial lesion biopsies of the uterine cervix. American Journal of Reproductive Immunology, 49 (1), 6-13. doi:10.1034/j.1600-0897.2003.01109.x
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Giannini, S., Hubert, P., Doyen, J., Boniver, J., & Delvenne, P. (February 2002). Influence of the mucosal epithelium microenvironment on Langerhans cells: implications for the development of squamous intraepithelial lesions of the cervix. International Journal of Cancer, 97 (5), 654-659. doi:10.1002/ijc.10084
Peer Reviewed verified by ORBi

Delvenne, P., Hubert, P., Jacobs, N., Giannini, S., Havard, L., Renard, I., Saboulard, D., & Boniver, J. (2001). The organotypic culture of HPV-transformed keratinocytes: an effective in vitro model for the development of new immunotherapeutic approaches for mucosal (pre)neoplastic lesions. Vaccine, 19 (17-19), 2557-64. doi:10.1016/S0264-410X(00)00489-8
Peer Reviewed verified by ORBi

Hubert, P., Giannini, S., Vanderplasschen, A., Franzen-Detrooz, E., Jacobs, N., Boniver, J., & Delvenne, P. (2001). Dendritic cells induce the death of human papillomavirus-transformed keratinocytes. FASEB Journal, 15 (13), 2521-2523. doi:10.1096/fj.00-0872fje
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Jacobs, N., Renard, I., Pisvin, S., Hubert, P., Boniver, J., & Delvenne, P. (2000). IL10 production in cultures of lymphocytes derived from biopsies of normal exocervix, transformation zone and squamous intraepithelial lesion. In J. Monsonego (Ed.), 4th International Multidisciplinary Congress - Eurogin 2000 (pp. 355-362). Pianoro, Italy: International Proceedings Division, Monduzzi Editore.

Hubert, P., van den Brule, F., Giannini, S., Franzen-Detrooz, E., Boniver, J., & Delvenne, P. (1999). Colonization of in vitro-formed cervical human papillomavirus-associated (pre)neoplastic lesions with dendritic cells: role of granulocyte/macrophage colony-stimulating factor. American Journal of Pathology, 154 (3), 775-784. doi:10.1016/S0002-9440(10)65324-2
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Jacobs, N., Giannini, S., Al-Saleh, W., Hubert, P., Boniver, J., & Delvenne, P. (1999). Generation of T lymphocytes from the epithelium and stroma of squamous pre-neoplastic lesions of the uterine cervix. Journal of Immunological Methods, 223 (1), 123-9. doi:10.1016/S0022-1759(98)00205-1
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Hubert, P., Greimers, R., Franzen-Detrooz, E., Sele, J., Delanaye, P., Boniver, J., & Delvenne, P. (October 1998). In Vitro Propagated Dendritic Cells from Patients with Human-Papilloma Virus-Associated Preneoplastic Lesions of the Uterine Cervix: Use of Flt3 Ligand. Cancer Immunology, Immunotherapy, 47 (2), 81-9. doi:10.1007/s002620050507
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