Profil

Herfs Michael

GIGA Cancer - Experimental Pathology

Département des sciences biomédicales et précliniques

See author's contact details
Main Referenced Co-authors
Delvenne, Philippe  (76)
Hubert, Pascale  (62)
Roncarati, Patrick  (47)
Bruyère, Diane  (31)
Hendrick, Elodie  (28)
Main Referenced Keywords
HPV (10); Humans (10); Myoferlin (8); Cancer (7); Female (6);
Main Referenced Unit & Research Centers
Giga-Cancer - ULiège [BE] (10)
GIGA‐R - Giga‐Research - ULiège [BE] (1)
Laboratoire de recherche sur les métastases (1)
d‐BRU - Dental Biomaterials Research Unit - ULiège [BE] (1)
Main Referenced Disciplines
Oncology (155)
Biochemistry, biophysics & molecular biology (12)
Immunology & infectious disease (10)
Microbiology (4)
Dermatology (3)

Publications (total 174)

The most downloaded
451 downloads
Herfs, M., Hubert, P., Kholod, N., Caberg, J.-H., Gilles, C., Berx, G., Savagner, P., Boniver, J., & Delvenne, P. (May 2008). Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression. American Journal of Pathology, 172 (5), 1391-402. doi:10.2353/ajpath.2008.071004 https://hdl.handle.net/2268/10032

The most cited

309 citations (Scopus®)

Herfs, M., Yamamoto, Y., Laury, A., Wang, X., Nucci, M. R., McLaughlin-Drubin, M. E., Munger, K., Feldman, S., McKeon, F. D., Xian, W., & Crum, C. P. (June 2012). A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proceedings of the National Academy of Sciences of the United States of America, 109 (26), 10516-21. doi:10.1073/pnas.1202684109 https://hdl.handle.net/2268/137494

Marin-Esteban, V., Molet, L., Laganà, M., Ciocan, D., Dominguez-Lafage, C., Alouche, N., Nguyen, J., Gallego, C., Mercier-Nomé, F., Jaracz-Ros, A., Beaupain, B., Bouligand, J., Proust, A., Habib, C., Bonnin, R. A., Girlich, D., Fouyssac, F., Schmutz, J.-L., Bursztejn, A.-C., ... Deback, C. (11 April 2024). CXCR4 Antagonist in HPV5-Associated Perianal Squamous-Cell Carcinoma. New England Journal of Medicine, 390 (14), 1339 - 1341. doi:10.1056/NEJMc2213180
Peer Reviewed verified by ORBi

Kim, S., Ghiringhelli, F., de la Fouchardière, C., Evesque, L., Smith, D., Badet, N., Samalin, E., Lopez-Trabada Ataz, D., Parzy, A., Desramé, J., Baba Hamed, N., Buecher, B., Tougeron, D., Bouché, O., Dahan, L., Chibaudel, B., El Hajbi, F., Mineur, L., Dubreuil, O., ... Borg, C. (April 2024). Atezolizumab plus modified docetaxel, cisplatin, and fluorouracil as first-line treatment for advanced anal cancer (SCARCE C17-02 PRODIGE 60): a randomised, non-comparative, phase 2 study. The Lancet Oncology, 25 (4), 518 - 528. doi:10.1016/S1470-2045(24)00081-0
Peer Reviewed verified by ORBi

Kervarrec, T., Appenzeller, S., Tallet, A., Jullie, M.-L., Sohier, P., Guillonneau, F., Rütten, A., Berthon, P., Le Corre, Y., Hainaut-Wierzbicka, E., Blom, A., Beneton, N., Bens, G., Nardin, C., Aubin, F., Dinulescu, M., Visée, S., Herfs, M., Touzé, A., ... Schrama, D. (2024). Detection of wildtype Merkel cell polyomavirus genomic sequence and VP1 transcription in a subset of Merkel cell carcinoma. Histopathology. doi:10.1111/his.15068
Peer Reviewed verified by ORBi

Reynders, C.* , Lerho, T.* , Goebel, E. A., Crum, C. P., Vandenput, S., Beaudart, C.* , & Herfs, M.*. (October 2023). Prevalence and genotype distribution of human papillomavirus in cervical adenocarcinoma (usual type and variants): A systematic review and meta-analysis. Journal of Medical Virology, 95 (10), 29190. doi:10.1002/jmv.29190
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Mourtada, J., Lony, C., Nicol, A., De Azevedo, J., Bour, C., Macabre, C., RONCARATI, P., Ledrappier, S., Schultz, P., Borel, C., Burgy, M., Wasylyk, B., Mellitzer, G., Herfs, M., Gaiddon, C., & Jung, A. C. (October 2023). A novel ΔNp63-dependent immune mechanism improves prognosis of HPV-related head and neck cancer. Frontiers in Immunology, 14, 1264093. doi:10.3389/fimmu.2023.1264093
Peer Reviewed verified by ORBi

Kervarrec, T., Tallet, A., Macagno, N., de la Fouchardière, A., Pissaloux, D., Tirode, F., Bravo, I. G., Nicolas, A., Baulande, S., Sohier, P., Balme, B., Osio, A., Jullie, M.-L., Moulonguet, I., Bonsang, B., Tournier, E., Herfs, M., Frouin, E., Zidan, A., ... Battistella, M. (2023). Sweat Gland Tumors Arising on Acral Sites: A Molecular Survey. American Journal of Surgical Pathology. doi:10.1097/PAS.0000000000002098
Peer Reviewed verified by ORBi

Ancion, M., Luyckx, M., Renard, M., Reynders, C., Lerho, T., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., Herfs, M., & Hubert, P. (12 June 2023). Approach using "second generation" immune checkpoint inhibitors for the treatment of triple-negative breast cancer [Poster presentation]. EACR 2023, Turin, Italy.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Luyckx, M., Renard, M., Delvenne, P., Hubert, P., & Herfs, M. (02 February 2023). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV in carcinogenesis [Poster presentation]. Séminaire des chercheurs Télévie 2023.

Mohring, V., Hubert, P., Ancion, M., Nokin, M.-J., Roncarati, P., Agirman, F., Maloujahmoum, N., Lardinois, F., Wissocq, T., Herfs, M., Peulen, O., & Janji, B. (2023). Enhancement of anti-tumor immunity through interference with glycation stress in breast cancer [Poster presentation]. GIGA day.

Bruyere, D., RONCARATI, P., Lebeau, A., Lerho, T., Poulain, F., Hendrick, E., Pilard, C., Reynders, C., Ancion, M., Luyckx, M., Renard, M., Jacob, Y., Twizere, J.-C., Peiffer, R., Peulen, O., Delvenne, P., Hubert, P., McBride, A., Gillet, N., ... Herfs, M. (2023). Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair. Theranostics, 13 (3), 1130 - 1149. doi:10.7150/thno.78091
Peer Reviewed verified by ORBi

Gallego, C., Jaracz-Ros, A., Laganà, M., Mercier-Nomé, F., Domenichini, S., Fumagalli, A., Roingeard, P., Herfs, M., Pidoux, G., Bachelerie, F., & Schlecht-Louf, G. (2023). Reprogramming of connexin landscape fosters fast gap junction intercellular communication in human papillomavirus-infected epithelia. Frontiers in Cellular and Infection Microbiology, 13, 1138232. doi:10.3389/fcimb.2023.1138232
Peer Reviewed verified by ORBi

Reynders, C., Roncarati, P., Ancion, M., Lerho, T., Bruyère, D., Delvenne, P., Hubert, P., & Herfs, M. (29 September 2022). Caractérisations histopathologiques des cancers œsophagiennes et potentiel implication des infections par HPV de haut-risques [Paper presentation]. Conférence annuelle de l'Association Francophone pour l'étude des Infections à Papillomavirus et Polyomavirus 2022, France.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Pilard, C., Bruyère, D., Hendrick, E., Delvenne, P., Hubert, P., & Herfs, M. (09 September 2022). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV in carcinogenesis [Poster presentation]. INTERUNIVERSITY PHD STUDENT DAY.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Pilard, C., Hendrick, E., Bruyère, D., Delvenne, P., Hubert, P., & Herfs, M. (06 September 2022). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV infections in carcinogenesis [Poster presentation]. GIGA-Day 2022.

Mohring, V., Wissocq, T., Hubert, P., Herfs, M., Tiamiou, A., Hasmim Meriem, Nokin, M.-J., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (September 2022). Immunosuppressive effect of methylglyoxal stress in breast cancer [Paper presentation]. Annual meeting of the Belgian Association for Cancer Research, Belgium.

Herfs, M. (September 2022). Molecular mapping of DNA repair hijacking by HPV oncoproteins [Paper presentation]. AFIPP (French Association for the Study of Papillomavirus and Polyomavirus infections) (edition 14th), Sedan, France.

Mohring, V., Wissocq, T., Hubert, P., Herfs, M., Tiamiou, A., Hasmim, M., Nokin, M.-J., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (21 June 2022). Methylglyoxal reshapes breast tumor immune microenvironment [Poster presentation]. European association for cancer research congress 2022, Séville, Spain.

Herfs, M. (June 2022). E6/E7 oncoproteins take part in the intrinsic radiosensitivity of HPV-driven cancers by directly interacting with various host DNA repair proteins [Paper presentation]. 6th Workshop on Emerging Issues in Oncogenic Virus Research, San Pietro in Bevagna, Italy.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Bruyère, D., Hendrick, E., Pilard, C., Delvenne, P., Hubert, P., & Herfs, M. (29 April 2022). Histopathological characterization of esophageal tumors and potential involvement of high-risk HPV in carcinogenesis [Paper presentation]. Séminaire du GIGA-Cancer, Belgium.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Hendrick, E., Bruyère, D., Pilard, C., Delvenne, P., Hubert, P., & Herfs, M. (08 April 2022). Histopathological characterization of esophageal cancers and potential role of high-risk HPV infections [Poster presentation]. Séminaire des chercheurs Télévie 2022, Belgium.

Herfs, M. (April 2022). Interplay between carcinogenic HPV infections and the vaginal microbiome [Paper presentation]. Televie Seminar.

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Straub Hogan, M. M., Spieker, A. J., Orejudos, M., Gheit, T., Herfs, M., Tommasino, M., Sanchez, D. F., Fernandez-Nestosa, M. J., Pena, M. D. C. R., Gordetsky, J. B., Epstein, J. I., Canete-Portillo, S., Gellert, L. L., Prieto Granada, C. N., Magi-Galluzzi, C., Cubilla, A. L., & Giannico, G. A. (2022). Pathological characterization and clinical outcome of penile intraepithelial neoplasia variants: a North American series. Modern Pathology. doi:10.1038/s41379-022-01020-y
Peer Reviewed verified by ORBi

Mohring, V., Wissocq, T., Hubert, P., Herfs, M., Tiamiou, A., Hasmim Meriem, Nokin, M.-J., Peulen, O., Castronovo, V., Janji, B., & Bellahcene, A. (2022). Methylglyoxal regulates the recruitment of tumor-infiltrating immunosuppressive cells in breast cancer [Poster presentation]. PhD Day UNamur 2022, Belgium.

Debernardi, A., Meurisse, A., Prétet, J.-L., Guenat, D., Monnien, F., Spehner, L., Vienot, A., RONCARATI, P., André, T., Abramowitz, L., Molimard, C., Mougin, C., Herfs, M., Kim, S., & Borg, C. (2022). Prognostic role of HPV integration status and molecular profile in advanced anal carcinoma: An ancillary study to the epitopes-HPV02 trial. Frontiers in Oncology, 12, 941676. doi:10.3389/fonc.2022.941676
Peer Reviewed verified by ORBi

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Pilard, C., Bruyère, D., Hendrick, E., Delvenne, P., Hubert, P., & Herfs, M. (14 December 2021). Histopathological characterization of esophageal cancers and potential role of high-risk HPV infections [Poster presentation]. Giga Cancer Day 2021.

Herfs, M. (November 2021). Deciphering the high susceptibility of uterine cervix for alpha HPV-related carcinogenesis: focus on a specific proteomic signature inherited from the cell originally infected [Paper presentation]. Harvard University (Brigham and Women's Hospital), Boston, United States.

Reynders, C., RONCARATI, P., Ancion, M., Lerho, T., Bruyère, D., Hendrick, E., Pilard, C., Hubert, P., Delvenne, P., & Herfs, M. (01 October 2021). Caractérisation histopathologique des cancers œsophagiens et potentiel rôle des HPV [Paper presentation]. Conférence annuelle de l'Association Francophone pour l'étude des Infections à Papillomavirus et Polyomavirus, France.

Bruyère, D., Monnien, F., Colpart, P., RONCARATI, P., Vuitton, L., Hendrick, E., Lepinoy, A., Luquain, A., Pilard, C., Lerho, T., Molimard, C., Maingon, P., Arnould, L., Bone-Lepinoy, M.-C., Dusserre, L., Martin, L., Reynders, C., Ancion, M., Peiffert, D., ... Herfs, M. (2021). Treatment algorithm and prognostic factors for patients with stage I–III carcinoma of the anal canal: a 20-year multicenter study. Modern Pathology, 34, 116-130. doi:10.1038/s41379-020-0637-6
Peer Reviewed verified by ORBi

Kerselidou, D., Dohai, B. S., Nelson, D. R., Daakour, S., De Cock, N., Hassoun, Z. E. O., Kim, D.-K., Olivet, J., El Assal, D. C., Jaiswal, A., Alzahmi, A., Saha, D., Pain, C., Matthijssens, F., Lemaitre, P., Herfs, M., Chapuis, J., Ghesquiere, B., Vertommen, D., ... Twizere, J.-C. (2021). Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells. Science Advances, 7 (19). doi:10.1126/sciadv.abe8349
Peer Reviewed verified by ORBi

Baudu, T., Parratte, Perez, V., Ancion, M., Millevoi, S., Hervouet, E., Peigney, A., Peixoto, P., Overs, A., Herfs, M., Fraichard, A., Guittaut, M., & Baguet, A. (2021). The NMD Pathway Regulates GABARAPL1 mRNA during the EMT. Biomedicines. doi:10.3390/biomedicines9101302
Peer Reviewed verified by ORBi

Pilard, C.* , Ancion, M.* , Delvenne, P., JERUSALEM, G., Hubert, P., & Herfs, M. (2021). Cancer immunotherapy: it’s time to better predict patients’ response. British Journal of Cancer, 125(7), 927-938. doi:10.1038/s41416-021-01413-x
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Hubert, P., RONCARATI, P., Demoulin, S., Pilard, C., Ancion, M., Reynders, C., Lerho, T., Bruyère, D., Lebeau, A., Radermecker, C., Meunier, M., Nokin, M.-J., Hendrick, E., Peulen, O., Delvenne, P., & Herfs, M. (2021). Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy. Journal for ImmunoTherapy of Cancer, 9 ((3)), 001966. doi:10.1136/jitc-2020-001966
Peer Reviewed verified by ORBi

Jacquet, M., Hervouet, E., Baudu, T., Herfs, M., Parratte, C., Feugeas, J.-P., Perez, V., Reynders, C., Ancion, M., Vigneron, M., Baguet, A., Guittaut, M., Fraichard, A., & Despouy, G. (2021). GABARAPL1 Inhibits EMT Signaling through SMAD-Tageted Negative Feedback. Biology. doi:10.3390/biology10100956
Peer reviewed

Pilard, C., RONCARATI, P., Hendrick, E., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (03 November 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Paper presentation]. Cytokines 2020, Seattle (Virtual), United States.

LAMBERT, V.* , hansen, S.* , Schoumacher, M.* , Lecomte, J., Leenders, J., Hubert, P., Herfs, M., Blacher, S., Carnet, O., Yip, C., BLAISE, P., DUCHATEAU, E., LOCHT, B., THYS, M., CAVALIER, E., GOTHOT, A., Govaerts, B., RAKIC, J.-M., Noël, A.* , & De Tullio, P.*. (2020). Pyruvate dehydrogenase kinase/lactate axis: a therapeutic target for neovascular age-related macular degeneration identified by metabolomics. Journal of Molecular Medicine. doi:10.1007/s00109-020-01994-9
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pilard, C., RONCARATI, P., Hendrick, E., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (03 October 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. 7th Immunotherapy of Cancer Conference (ITOC7), Munich (Virtual), Germany.

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (01 October 2020). P08.03 Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy. Journal for ImmunoTherapy of Cancer, 8 (Suppl 2), 50-A51. doi:10.1136/jitc-2020-ITOC7.99

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (07 February 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. BACR 2020, Jette, Belgium.

Pilard, C., RONCARATI, P., Hendrick, E., Lebeau, A., Bruyère, D., Lerho, T., Ancion, M., Reynders, C., DELVENNE, P., Herfs, M., & Hubert, P. (29 January 2020). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Télévie Seminar 2020, Bruxelles, Belgium.

Nokin, M.-J., Darbo, E., Travert, C., Drogat, B., Lacouture, A., San José, S., Cabrera, N., Turcq, B., Prouzet-Mauleon, V., Falcone, M., Villanueva, A., Wang, H., Herfs, M., Mosteiro, M., Jänne, P. A., Pujol, J.-L., Maraver, A., Barbacid, M., Nadal, E., ... Ambrogio, C. (2020). Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma. JCI Insight. doi:10.1172/jci.insight.137869
Peer Reviewed verified by ORBi

Lachat, C., Bruyère, D., Etcheverry, A., Aubry, M., Mosser, J., Warda, W., Herfs, M., Hendrick, E., Ferrand, C., Borg, C., Delage-Mourroux, R., Feugeas, J.-P., Guittaut, M., Hervouet, E., & Peixoto, P. (2020). EZH2 and KDM6B Expressions Are Associated with Specific Epigenetic Signatures during EMT in Non Small Cell Lung Carcinomas. Cancers, 12, 3649-3671. doi:10.3390/cancers12123649
Peer Reviewed verified by ORBi

Herfs, M. (18 December 2019). Association between HPV infection and bacterial vaginosis [Paper presentation]. NAREPI congress, Namur, Belgium.

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (26 November 2019). Myoferlin depletion induces DNA damage response and p53- dependent cell cycle arrest and apoptosis in colon cancer [Poster presentation]. Metabolism in Cancer and Stromal Cells (2nd edition), Leuven, Belgium.

Herfs, M. (November 2019). HPV infection in squamo-columnar junctions: from cellular characterization to patient outcome [Paper presentation]. University of Tuebingen, Tuebingen, Germany.

Herfs, M. (19 October 2019). A dualistic model of squamous carcinoma and adenocarcinoma of the anal canal with implications for personalised medicine [Paper presentation]. Belgian Week of Pathology, Bruxelles, Belgium.

LEBAS, E., DORMAL, M., Herfs, M., ARRESE ESTRADA, J., & NIKKELS, A. (July 2019). Simultaneous condylomata acuminata and squamous cell carcinoma of the penis with different HPV genotypes. European Journal of Dermatology, 29 (4), 433-435. doi:10.1684/ejd.2019.3578
Peer Reviewed verified by ORBi

Dewez, F., Martin-Lorenzo, M., Herfs, M., Baiwir, D., Mazzucchelli, G., De Pauw, E., Heeren, R. M. A., & Balluff, B. (14 June 2019). Precise co-registration of mass spectrometry imaging, histology, and laser microdissection-based omics. Analytical and Bioanalytical Chemistry, 411, 5647-5653. doi:10.1007/s00216-019-01983-z
Peer Reviewed verified by ORBi

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (21 May 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Immunology Day 2019, Liège, Belgium.

Herfs, M. (18 May 2019). Cancer stem cells in HPV-related cancer [Paper presentation]. 1st Cologne Symposium on missing links in HPV biology, Koln, Germany.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (01 February 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. BACR 2019, Anvers, Belgium.

Verrillo, G., Hanache, S., Duchemin, A., Herfs, M., DELVENNE, P., Tassin, A.-M., Vernos, I., Orange, F., Martin, M., Dequiedt, F., Twizere, J.-C., & Mottet, D. (February 2019). Unveiling of a new role for DPF3 protein in cancer biology [Poster presentation]. Belgian Association for Cancer Research (BACR) meeting 2019.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (28 January 2019). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. Télévie Seminar 2019, Gembloux, Belgium.

Herfs, M. (28 January 2019). HMGB1: a novel immunotherapeutic target [Paper presentation]. Televie Seminar, Gembloux, Belgium.

Medfai, H., Khalil, A., Rousseau, A., Nuyens, V., Paumann-Page, M., Sevcnikar, B., Furtmüller, P., Obinger, C., Moguilevsky, N., Peulen, O., Herfs, M., Castronovo, V., Amri, M., Van Antwerpen, P., Vanhamme, L., & Zouaoui Boudjeltia, K. (2019). Human peroxidasin 1 promotes angiogenesis through ERK1/2, Akt and FAK pathways. Cardiovascular Research, 115(2), 463-475. doi:10.1093/cvr/cvy179
Peer Reviewed verified by ORBi

Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., CHARLOTEAUX, B., Verbeke, L., van Laere, S., RONCARATI, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21(1, 11. doi:10.1186/s13058-018-1095-7
Peer Reviewed verified by ORBi

Peixoto, P., Etcheverry, A., Aubry, M., Missey, A., Lachat, C., Perrard, J., Hendrick, E., Delage-Mourroux, R., Mosser, J., Borg, C., Feugeas, J.-P., Herfs, M., Boyer-Guittaut, M., & Hervouet, E. (2019). EMT is associated with an epigenetic signature of ECM remodeling genes. Cell Death and Disease, 10 (3), 205. doi:10.1038/s41419-019-1397-4
Peer Reviewed verified by ORBi

Paget-Bailly, P., Meznad, K., Bruyère, D., Perrard, J., Herfs, M., Jung, A., Mougin, C., Pretet, J.-L., & Baguet, A. (2019). Comparative RNA sequencing reveals that HPV16 E6 abrogates the effect of E6*I on ROS metabolism. Scientific Reports, 11, 5938. doi:10.1038/s41598-019-42393-6
Peer Reviewed verified by ORBi

Song, S., Bruyère, D., Devins, K., Lebeau, A., Reyes, C., & Herfs, M. (2019). Cervical Carcinogenesis, Early Detection and Prevention. In Gynecologic and Obstetric Pathology, Volume 1 (pp. 279-291). Springer.
Peer reviewed

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Peiffer, R., Agirman, F., Maloujahmoum, N., Habraken, Y., Delvenne, P., Bellahcene, A., Castronovo, V.* , & Peulen, O.*. (2019). Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis. Oncogenesis. doi:10.1038/s41389-019-0130-6
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Watkins, J., Yang, E., Crum, C., Herfs, M., Gheit, T., Tommasino, M., & Nucci, M. (2019). Classic Vulvar Intraepithelial Neoplasia With Superimposed Lichen Simplex Chronicus: A Unique Variant Mimicking Differentiated Vulvar Intraepithelial Neoplasia. International Journal of Gynecological Pathology, 38(2), 175-182. doi:10.1097/PGP.0000000000000509
Peer Reviewed verified by ORBi

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (2019). Human colon cancer overexpress myoferlin to maintain a fit mitochondrial network and escape p53 dependent apoptosis [Poster presentation]. Belgian Association for Cancer Research Congress, Anvers, Belgium.

Pottier, C., Kriegsmann, M., Alberts, D., Smargiasso, N., Baiwir, D., Mazzucchelli, G., Herfs, M., Fresnais, M., Casadonte, R., Delvenne, P., De Pauw, E., & Longuespée, R. (2019). Microproteomic Profiling of High-Grade Squamous Intraepithelial Lesion of the Cervix: Insight into Biological Mechanisms of Dysplasia and New Potential Diagnostic Markers. Proteomics. Clinical Applications, 13(1). doi:10.1002/prca.201800052
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Kervarrec, T., Tallet, A., Miquelestorena-Standley, E., Houben, R., Schrama, D., Gambichler, T., Berthon, P., Le Corre, Y., Hainaut-Wierzbicka, E., Aubin, F., Bens, G., Tabareau-Delalande, F., Beneton, N., Fromont, G., Arbion, F., Leteurtre, E., Herfs, M., Touzé, A., Samimi, M., & Guyétant, S. (2019). Morphologic and immunophenotypical features distinguishing Merkel cell polyomavirus-positive and negative Merkel cell carcinoma. Modern Pathology, 32, 1605-1616. doi:10.1038/s41379-019-0288-7
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Claude-Taupin, A., Fonderflick, L., Gauthier, T., Mansi, L., Pallandre, J.-R., Borg, C., Perez, V., Monnien, F., Algros, M.-P., Vigneron, M., Adami, P., Delage-Mourroux, R., Peixoto, P., Herfs, M., Boyer-Guittaut, M., & Hervouet, E. (December 2018). ATG9A Is Overexpressed in Triple Negative Breast Cancer and Its In Vitro Extinction Leads to the Inhibition of Pro-Cancer Phenotypes. Cells, 7(12). doi:10.3390/cells7120248
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Herfs, M. (28 November 2018). HMGB1: une nouvelle cible immuno-thérapeutique [Paper presentation]. Séminaire de l'UMR1098, Besançon, France.

Pilard, C., RONCARATI, P., Lebeau, A., Bruyère, D., Hendrick, E., DELVENNE, P., Herfs, M., & Hubert, P. (13 September 2018). Combining PD-1/PD-L1 blockade and RANKL inhibitors to treat breast cancers unresponsive to standard therapy [Poster presentation]. GIGA-Cancer Day 2018, Liège, Belgium.

Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Herfs, M., Thiry, M., Bellahcene, A., Castronovo, V., & Peulen, O. (01 July 2018). Myoferlin controls mitochondrial structure and metabolism in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness [Poster presentation]. EACR 25 50 Years, Amsterdam, Netherlands.

Herfs, M. (31 May 2018). Identification and characterization of two distinct subtypes of anal adenocarcinoma [Paper presentation]. 5th Workshop on Emerging Issues in Oncogenic Virus Research, San Pietro in Bevagna, Italy.

Bruyère, D., Lebeau, A., RONCARATI, P., Hendrick, E., Masson, M., Twizere, J.-C., Pilard, C., Hubert, P., DELVENNE, P., & Herfs, M. (30 May 2018). Deciphering the radiosensitivity of HPV-positive tumors [Poster presentation]. 5th meeting on emerging issues in oncogenic virus research, San Pietro in Bevagna, Italy.

Bruyère, D., Lebeau, A., RONCARATI, P., Hendrick, E., Masson, M., Twizere, J.-C., Pilard, C., Hubert, P., DELVENNE, P., & Herfs, M. (28 May 2018). Deciphering the radiosensitivity of HPV-positive tumors [Poster presentation]. EDT-Immunology day 2018, Liège, Belgium.

Lebeau, A., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., TAZIAUX, S., Hubert, P., Delvenne, P., & Herfs, M. (28 May 2018). HPV-related innate peptide inhibition promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Immunology day 2018, Liège, Belgium.

Herfs, M. (20 April 2018). HPV mucocutaneous infections [Paper presentation]. European Academy of Dermatology and Venereology, Liege, Belgium.

Rademaker, G., Hennequière, V., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Bettendorff, L., Deroanne, C., Thiry, M., Delvenne, P., Hustinx, R., Bellahcene, A., Castronovo, V., & Peulen, O. (April 2018). Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene, 37 ((32)), 4398-4412. doi:10.1038/s41388-018-0287-z
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Lebeau, A., Bruyère, D., Hendrick, E., Pilard, C., RONCARATI, P., TAZIAUX, S., Hubert, P., Delvenne, P., & Herfs, M. (01 February 2018). HPV-related innate peptide inhibition promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Annual Televie seminar, Bruxelles, Belgium.

Verrillo, G., Hanache, S., Duchemin, A., Herfs, M., DELVENNE, P., Tassin, A.-M., Dequiedt, F., Twizere, J.-C., & Mottet, D. (01 February 2018). Unveiling a New Role of DPF3 Protein in Cancer Biology [Poster presentation]. Télévie's Researchers Seminar 2018.

Asgarova, A., Asgarov, K., Godet, Y., Peixoto, P., Nadaradjane, A., Boyer-Guittaut, M., Galaine, J., Guenat, D., Mougey, V., Perrard, J., Pallandre, J.-R., Bouard, A., Balland, J., Tirole, C., Adotevi, O., Hendrick, E., Herfs, M., Cartron, P.-F., Borg, C., & Hervouet, E. (2018). PD-L1 expression is regulated by both DNA methylation and NF-kB during EMT signaling in non-small cell lung carcinoma. Oncoimmunology, 7(5), 1423170. doi:10.1080/2162402X.2017.1423170
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Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., Bellier, J., Costanza, B., Herfs, M., Bettendorff, L., Deroanne, C., Delvenne, P., HUSTINX, R., Bellahcene, A., Castronovo, V., & Peulen, O. (2018). Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma and affects tumor aggressiveness [Poster presentation]. Bioforum Uliège.

Jeffreys, M., Jeffus, S., Herfs, M., & Quick, C. (2018). Accentuated p53 staining in usual type vulvar dysplasia—A potential diagnostic pitfall. Pathology - Research and Practice, 214(1), 76-79. doi:10.1016/j.prp.2017.11.009
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Herfs, M. (January 2018). HPV infection in mucosal junctions: a novel paradigm but several unresolved issues [Paper presentation]. University of Heidelberg/DKFZ, Heidelberg, Germany.

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (2018). Myoferlin depletion induces DNA damage response and p53 dependent cell cycle arrest and apoptosis in colon cancer [Poster presentation]. Third Symposium of UBRC, Bruxelles, Belgium.

Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Anania, S., Bettendorff, L., Deroanne, C., Thiry, M., Delvenne, P., HUSTINX, R., Bellahcene, A., Castronovo, V., & Peulen, O. (2018). Myoferlin controls mitochondrial structure and activity in pancreatic cancer and affects tumor aggressiveness [Poster presentation]. Belgian Association for Cancer Research Congress.

Herfs, M., RONCARATI, P., KOOPMANSCH, B., Peulen, O., Bruyère, D., Lebeau, A., Hendrick, E., Hubert, P., PONCIN, A., Penny, W., Piazzon, N., Monnien, F., Guenat, D., Mougin, C., Prétet, J.-L., Vuitton, L., SEGERS, K., LAMBERT, F., BOURS, V., ... Delvenne, P. (2018). A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalized medicine. British Journal of Cancer, 118(10), 1302-1312. doi:10.1038/s41416-018-0049-2
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Pohthipornthawat, N., Feldman, S., Granter, S., Laga, A., Crum, C., & Herfs, M. (2018). Epidermodysplasia Verruciformis–like HPV infection of the Vulva in Immunosuppressed Women. International Journal of Gynecological Pathology, 37(3), 233-238. doi:10.1097/PGP.0000000000000417
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Herfs, M. (15 December 2017). Viral Carcinogenesis: from molecular mechanisms to hepatocellular, cervical, anal and head and neck cancers [Paper presentation]. Workshop Immunothérapies Grand Ouest (infection et cancer), Nantes, France.

Herfs, M. (October 2017). HPV infection in mucosal junctions: a novel paradigm but several unresolved issues [Paper presentation]. University of Paris-Sud, Clamart, France.

Herfs, M. (29 September 2017). Adénocarcinome du canal anal: identification de deux sous-types distincts [Paper presentation]. AFIPP (French association for the study of papillomavirus and polyomavirus infections) (edition 10th), Saint Foy Les Lyon, France.

Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Bettendorff, L., Deroanne, C., Delvenne, P., Hustinx, R., Bellahcene, A., Castronovo, V., & Peulen, O. (22 September 2017). Myoferlin controls mitochondrial structure in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness [Poster presentation]. Second U-CRC Symposium, Bruxelles, Belgium.

Herfs, M. (August 2017). HPV infection in mucosal junctions: a novel paradigm but several unresolved issues [Paper presentation]. Brigham and Women's Hospital, Boston, United States.

Verrillo, G., Hanache, S., Duchemin, A., Herfs, M., DELVENNE, P., Tassin, A.-M., Dequiedt, F., Twizere, J.-C., & Mottet, D. (11 May 2017). Unveiling a New Role of DPF3 Protein in Cancer Biology [Poster presentation]. PhD Day.

Herfs, M., Soong, T. R., Delvenne, P., & Crum, C. (April 2017). Deciphering the Multifactorial Susceptibility of Mucosal Junction Cells to HPV Infection and Related Carcinogenesis. Viruses, 9 (4), 85. doi:10.3390/v9040085
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Herfs, M. (March 2017). Identification of two anal cancer subtypes displaying distinct proteomic signatures and clinicopathological features [Paper presentation]. HPV2017: international papillomavirus conference, Cape Town, South Africa.

Lebeau, A., Bruyère, D., RONCARATI, P., DELVENNE, P., Hubert, P., & Herfs, M. (01 February 2017). HPV-mediated innate peptide down-regulation promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. GIGA Day 2017, Liège, Belgium.

Verrillo, G., Duchemin, A., Hanache, S., Herfs, M., DELVENNE, P., Tassin, A.-M., Dequiedt, F., Twizere, J.-C., & Mottet, D. (01 February 2017). Unveiling a New Role of DPF3 Protein in Cancer Biology [Poster presentation]. Giga Day.

Balsat, C., Blacher, S., Herfs, M., Van De Velde, M., Signolle, N., Sauthier, P., Pottier, C., Gofflot, S., De Cuypere, M., Delvenne, P., Goffin, F., Noël, A.* , & Kridelka, F.*. (February 2017). A specific immune and lymphatic profile characterizes the pre-metastatic state of the sentinel lymph node in patients with early cervical cancer. Oncoimmunology, 6 (2), 1265718. doi:10.1080/2162402X.2016.1265718
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* These authors have contributed equally to this work.

Herfs, M., Chang, M., & Crum, C. (2017). Papillomaviruses and cervical neoplasia. In Holland-Frei Cancer Medicine, ninth edition. John Wiley & Sons, Inc.

Herfs, M., Longuespée, R., Quick, C., RONCARATI, P., Suarez-Carmona, M., Hubert, P., Lebeau, A., Bruyère, D., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Lai, K., Dunn, A., Obregon, F., Yang, E., De Pauw, E., Crum, C., & Delvenne, P. (2017). Proteomic signatures reveal a dualistic and clinically relevant classification of anal canal carcinoma. Journal of Pathology, 241, 522-533. doi:10.1002/path.4858
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Lebeau, A., Bruyère, D., RONCARATI, P., Delvenne, P., Hubert, P., & Herfs, M. (08 December 2016). HPV-mediated innate peptide down-regulation promotes the acquisition of bacterial/fungal infections within the genital tract [Poster presentation]. Televie Seminar, Bruxelles, Belgium.

Herfs, M. (September 2016). Cancer du canal anal: identification de deux sous-types distincts [Paper presentation]. AFIPP (French association for the study of papillomavirus and polyomavirus infections) (edition 9th), Loches, France.

Howitt, B., Herfs, M., Tomoka, T., Kamiza, S., Gheit, T., Tommasino, M., Delvenne, P., Crum, C., & Milner, D. (August 2016). Comprehensive Human Papilloma Virus (HPV) Genotyping in Cervical Squamous Cell Carcinomas and its Relevance to Cervical Cancer Prevention in Malawian Women. Journal of Global Oncology, 3, 227-234.
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Herfs, M. (May 2016). Cellular origin of HPV-related (pre)cancer [Paper presentation]. f-TALES Antwerp Viral Induced Carcinogenesis, Antwerpen, Belgium.

Longuespée, R., Alberts, D., Pottier, C., Smargiasso, N., Mazzucchelli, G., Baiwir, D., Kriegsmann, M., Herfs, M., Kriegsmann, J., Delvenne, P., & De Pauw, E. (2016). A laser microdissection-based workflow for FFPE tissue microproteomics: important considerations for small sample processing. Methods, 104, 154-162. doi:10.1016/j.ymeth.2015.12.008
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Huang, E., Tomic, M., Hanamornroongruang, S., Meserve, E., Herfs, M.* , & Crum, C.*. (2016). p16ink4 and cytokeratin 7 immunostaining in predicting HSIL outcome for low-grade squamous intraepithelial lesions: A case series, literature review and commentary. Modern Pathology, 1501-1510. doi:10.1038/modpathol.2016.141
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* These authors have contributed equally to this work.

Herfs, M. (26 October 2015). HPV infection, squamo-columnar junction and potential cancer prevention [Paper presentation]. Belgian HPV platform meeting/conference, gent, Belgium.

Herfs, M. (01 October 2015). Transcriptionally active HPV infection in the cervical squamo-columnar junction [Paper presentation]. AFIPP (French association for the study of papillomavirus and polyomavirus infections ) (edition 8th), Rouilly-Sacey, France.

Herfs, M. (20 September 2015). Pathways of recurrent high-grade squamous intraepithelial lesions of the cervix [Paper presentation]. HPV2015: international papillomavirus conference, Lisbon, Portugal.

Herfs, M. (May 2015). HPV infection, squamo-columnar junction and cancer prevention [Paper presentation]. Symposium University of Kobe - University of Liege, Kobe, Japan.

Herfs, M., & Crum, C. (2015). Cervical cancer: Squamocolumnar junction ablation-tying up loose ends? Nature Reviews Clinical Oncology, 12 (7), 378-380. doi:10.1038/nrclinonc.2015.104
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FRANCHIMONT, C., Hermanns-Lê, T., PAQUET, P., Herfs, M., Delvenne, P., & PIERARD, G. (2015). Hedgehog- and mTOR-targeted therapies for advanced basal cell carcinomas. Future Oncology, 11, 2997-3002. doi:10.2217/fon.15.181
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Pottier, C., Wheatherspoon, A., RONCARATI, P., Longuespée, R., Herfs, M., Duray, A., Delvenne, P., & Quatresooz, P. (2015). The importance of the tumor microenvironment in the therapeutic management of cancer. Expert Review of Anticancer Therapy, 15, 943-954. doi:10.1586/14737140.2015.1059279
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Suarez-Carmona, M., Hubert, P., Delvenne, P., & Herfs, M. (2015). Defensins: « simple » antimicrobial peptides or broad-spectrum molecules ? Cytokine and Growth Factor Reviews, 26, 361-370. doi:10.1016/j.cytogfr.2014.12.005
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Demoulin, S., Herfs, M., SOMJA, J., RONCARATI, P., Delvenne, P., & Hubert, P. (2015). HMGB1 secretion during cervical carcinogenesis promotes the acquisition of a tolerogenic functionality by plasmacytoid dendritic cells. International Journal of Cancer, 137, 345-358. doi:10.1002/ijc.29389
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Herfs, M., & Crum, C. P. (2015). Response to "Two major pathways of recurrent high-grade squamous intraepithelial lesions of the cervix". International Journal of Cancer, 137, 2522-2523. doi:10.1002/ijc.29116
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Yang, E. J., Quick, C. M., Hanamornroongruang, S., Lai, K., Doyle, L., McKeon, F. D., Xian, W., Crum, C. P., & Herfs, M. (2015). Microanatomy of the cervical and anorectal squamocolumnar junctions: a proposed model for anatomical differences in HPV-related cancer risk. Modern Pathology, 28, 994-1000. doi:10.1038/modpathol.2015.54
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Hanns, E., Job, S., Coliat, P., Wasylyk, C., Ramolu, L., Pencreach, E., Suarez-Carmona, M., Herfs, M., Ledrappier, S., Macabre, C., Abecassis, J., Wasylyk, B., & Jung, A. (2015). Human Papillomavirus-related tumours of the oropharynx display a lower tumour hypoxia signature. Oral Oncology, 51, 848-856. doi:10.1016/j.oraloncology.2015.06.003
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Herfs, M., SOMJA, J., Howitt, B. E., Suarez-Carmona, M., KUSTERMANS, G., Hubert, P., DOYEN, J., GOFFIN, F., Kridelka, F., Crum, C. P., & Delvenne, P. (2015). Unique recurrence patterns of cervical intraepithelial neoplasia following excision of the squamo-columnar junction. International Journal of Cancer, 136, 1043-1052. doi:10.1002/ijc.28978
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Mirkovic, J., Howitt, B., RONCARATI, P., Demoulin, S., Suarez-Carmona, M., Hubert, P., Mckeon, F., Xian, W., Delvenne, P., Crum, C. P., & Herfs, M. (2015). Carcinogenic HPV infection in the cervical squamo-columnar junction. Journal of Pathology, 236, 265-271. doi:10.1002/path.4533
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Demoulin, S., SOMJA, J., duray, A., guenin, S., RONCARATI, P., DELVENNE, P., Herfs, M.* , & Hubert, P.*. (2015). Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion. Oncoimmunology, 6. doi:10.1080/2162402X.2015.1008334
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* These authors have contributed equally to this work.

Herfs, M. (December 2014). Implication of Squamocolumnar junction cells in the pathogenesis of cervical (pre)neoplastic lesions [Paper presentation]. European Society of gynecology and colposcopy, Berlin, Germany.

Herfs, M. (October 2014). Squamocolumnar junction cells and HPV infection [Paper presentation]. Agence nationale de recherches sur le sida et les hépatites virales (ANRS), Paris, France.

Herfs, M. (May 2014). Defensins in (lymph)angiogenesis [Paper presentation]. GIGA Cancer day, Liege, Belgium.

Hubert, P.* , Herman, L.* , RONCARATI, P., Maillard, C., Renoux, V., Demoulin, S., Erpicum, C., Foidart, J.-M., Boniver, J., Noël, A., Delvenne, P., & Herfs, M. (2014). Altered alpha-defensin 5 expression in cervical squamocolumnar junction: implication in the formation of a viral/tumour-permissive microenvironment. Journal of Pathology, 234 (4), 464-77. doi:10.1002/path.4435
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* These authors have contributed equally to this work.

Suarez-Carmona, M., Hubert, P., Gonzalez, A., Duray, A., RONCARATI, P., Erpicum, C., Boniver, J., Castronovo, V., Noël, A., Saussez, S., Peulen, O., Delvenne, P., & Herfs, M. (2014). DeltaNp63 isoform-mediated beta-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma. Oncotarget, 5 (7), 1856-1868. doi:10.18632/oncotarget.1819
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Herfs, M. (January 2014). Implication of squamocolumnar junction cells in the pathogenesis of cervical cancer [Paper presentation]. International Agency for Research on Cancer (IARC), Lyon, France.

Ning, G., Bijron, J. G., Yamamoto, Y., Wang, X., Howitt, B. E., Herfs, M., Yang, E., Hong, Y., Cornille, M., Wu, L., Hanamornroongruang, S., McKeon, F. D., Crum, C. P., & Xian, W. (2014). The PAX2-null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium. Journal of Pathology, 234, 478-487. doi:10.1002/path.4417
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Demoulin, S., Somja, J., Herfs, M., RONCARATI, P., Delvenne, P., & Hubert, P. (December 2013). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. 4th International Workshop on plasmacytoid dendritic cells, Paris, France.

Herfs, M. (November 2013). Implication of squamocolumnar junction cells in the pathogenesis of cervical cancer [Paper presentation]. Journée du Canceropôle de Grand Est, Strasbourg, France.

Herfs, M. (November 2013). Origins of cervical disease and biomarker selection [Paper presentation]. Eurogin, Florence, Italy.

Herfs, M. (September 2013). Implication of squamocolumnar junction cells in the pathogenesis of cervical cancer [Paper presentation]. AFIPP (French association for the study of papillomavirus and polyomavirus infections ), Luxeuil les bains, France.

Herfs, M. (May 2013). Squamocolumnar Junction-Specific Markers Define Biologically and Clinically Distinct Subsets of Low-Grade Cervical Intraepithelial Neoplasia [Paper presentation]. Giga-Cancer Day, Liège, Belgium.

Herfs, M. (March 2013). Squamocolumnar Junction-Specific Markers Define Biologically and Clinically Distinct Subsets of Low-Grade Cervical Intraepithelial Neoplasia [Paper presentation]. United States and Canadian Acadmy of Pathology, Baltimore, United States.

Herfs, M. (March 2013). The Cervical Squamocolumnar Junction Is Not the Same as the “Transformation Zone”: Evidence for Two Related but Divergent Populations with Different Cancer Risks [Paper presentation]. United States and Canadian Acadmy of Pathology, Baltimore, United States.

Howitt, B. E., Herfs, M., Brister, K., Oliva, E., Longtine, J., Hecht, J. L., & Nucci, M. R. (2013). Intestinal-type endocervical adenocarcinoma in situ: an immunophenotypically distinct subset of AIS affecting older women. American Journal of Surgical Pathology, 37 (5), 625-33. doi:10.1097/PAS.0b013e318285be00
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Ning, G., Yuan, J., Herfs, M., Yamamoto, Y., Bijron, J., McKeon, F., Xian, W., & Crum, C. (2013). Evidence That High-Grade Serous Cancers and Their Precursors Arise from a PAX2-Negative Progenitor Cell in the Oviduct [Poster presentation]. United States and Canadian Acadmy of Pathology, Baltimore, United States.

Herfs, M., & Crum, C. (2013). Laboratory management of cervical intraepithelial neoplasia: proposing a new paradigm. Advances in Anatomic Pathology, 20, 86-94. doi:10.1097/PAP.0b013e3182862aab
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Parra-Herran, C., Herfs, M., Doria, M., Crum, C. P., & Nucci, M. R. (2013). Giant Condyloma of the Cervix: An Uncommon Entity Associated With Low-risk Human Papilloma Virus Infection. American Journal of Surgical Pathology, 37 (2), 300-4. doi:10.1097/PAS.0b013e31826d261e
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Herfs, M., Vargas, S. O., Yamamoto, Y., Howitt, B. E., Nucci, M. R., Hornick, J. L., McKeon, F. D., Xian, W., & Crum, C. P. (2013). A novel blueprint for "top down" differentiation defines the cervical squamocolumnar junction during development, reproductive life and neoplasia. Journal of Pathology, 229 (3), 460-8. doi:10.1002/path.4110
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Jimenez, C., Howitt, B., Nucci, M., Quade, B., Crum, C., & Herfs, M. (2013). Predictive Value of Squamo-Columnar Junction Markers and p16ink4 in Multi-Observer Classification of Cervical Precursor Lesions [Poster presentation]. United States and Canadian Acadmy of Pathology, Baltimore, United States.

Howitt, B., Herfs, M., Ning, G., & Crum, C. (2013). Expression of Embryonic Markers in Endometrial Epitheliium: A Unique Topography with Implications for Tumorigenesis [Poster presentation]. United States and Canadian Acadmy of Pathology, Baltimore, United States.

Herfs, M., Parra-Herran, C., Howitt, B. E., Laury, A. R., Nucci, M. R., Feldman, S., Jimenez, C. A., McKeon, F. D., Xian, W., & Crum, C. P. (2013). Cervical squamocolumnar junction-specific markers define distinct, clinically relevant subsets of low-grade squamous intraepithelial lesions. American Journal of Surgical Pathology, 37 (9), 1311-8. doi:10.1097/PAS.0b013e3182989ee2
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Demoulin, S., Herfs, M., Delvenne, P., & Hubert, P. (2013). Tumor microenvironment converts plasmacytoid dendritic cells into immunosuppressive/tolerogenic cells: insight into the molecular mechanisms. Journal of Leukocyte Biology, 93 (3), 343-352. doi:10.1189/jlb.0812397
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Crum, C. P.* , Herfs, M.* , Ning, G.* , Bijron, J. G., Howitt, B. E., Jimenez, C. A., Hanamornroongruang, S., McKeon, F. D., & Xian, W. (2013). Through the glass darkly: intraepithelial neoplasia, top-down differentiation and the road to ovarian cancer. Journal of Pathology, 231, 402-412. doi:10.1002/path.4263
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* These authors have contributed equally to this work.

Somja, J., Demoulin, S., RONCARATI, P., Herfs, M., BLETARD, N., Delvenne, P., & Hubert, P. (2013). Dendritic cells in Barrett's esophagus carcinogenesis: an inadequate microenvironment for antitumor immunity? American Journal of Pathology, 182, 2168-2179. doi:10.1016/j.ajpath.2013.02.036
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Jimenez, C. P., Crum, C., & Herfs, M. (2013). Vaginal Squamous Cell Carcinoma and Intraepithelial Neoplasia Do Not Express Selected Junctional Markers Expressed in Cervical Carcinoma [Poster presentation]. United States and Canadian Acadmy of Pathology, Baltimore, United States.

Herfs, M., Yamamoto, Y., Laury, A., Wang, X., Nucci, M. R., McLaughlin-Drubin, M. E., Munger, K., Feldman, S., McKeon, F. D., Xian, W., & Crum, C. P. (June 2012). A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proceedings of the National Academy of Sciences of the United States of America, 109 (26), 10516-21. doi:10.1073/pnas.1202684109
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Herfs, M. (March 2012). A candidate cell of origin for cervical cancer [Paper presentation]. United States and Canadian Acadmy of Pathology, Vancouver, Canada.

Crum, C. P., Xian, W., McKeon, F., Yamamoto, Y., & Herfs, M. (2012). Novel Diagnosis and Therapeutic Targets for Cervical Cancer.

Herfs, M., Hubert, P., POIRRIER, A.-L., Vandevenne, Renoux, V., Habraken, Y., Cataldo, D., Boniver, J., & Delvenne, P. (2012). Proinflammatory Cytokines Induce Bronchial Hyperplasia and Squamous Metaplasia in Smokers: Implications for chronic obstructive pulmonary disease therapy. American Journal of Respiratory Cell and Molecular Biology, 47 (1), 67-79. doi:10.1165/rcmb.2011-0353OC
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Parra-Herran, C. P., Lane, B., Hirsch, M., Nucci, M., Crum, C., & Herfs, M. (2012). Immature Metaplastic CIN1: A Variant with Intense P16 Staining and Low Proliferative Index [Poster presentation]. United States and Canadian Acadmy of Pathology, Baltimore, United States.

Herfs, M. (November 2011). A candidate cell of origin for cervical cancer [Paper presentation]. Brigham and Women's Hospital, Boston, United States.

Herfs, M., Hubert, P., Moutschen, M., & Delvenne, P. (07 January 2011). Mucosal junctions: open doors to HPV and HIV infections? Trends in Microbiology, 19 (3), 114-120. doi:10.1016/j.tim.2010.12.006
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Demoulin, S., Herfs, M., Somja, J., Delvenne, P., Hubert, P., & RONCARATI, P. (2011). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. miRNA symposium, Namur, Belgium.

Ernoux-Neufcoeur, P., Arafa, M., Decaestecker, C., Duray, A., Remmelink, M., Leroy, X., Herfs, M., Somja, J., Depuydt, C. E., Delvenne, P., & Saussez, S. (January 2011). Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma. Journal of Cancer Research and Clinical Oncology, 137 (1), 173-81. doi:10.1007/s00432-010-0871-2
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Demoulin, S., Somja, J., Herfs, M., Delvenne, P., & Hubert, P. (2011). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. GIGA Cancer Day, Liège, Belgium.

Boniver, J., & Herfs, M. (2011). Les cellules souches cancereuses. Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique, 166 (3-4), 141-5; discussion 146.
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Demoulin, S., Herfs, M., Somja, J., RONCARATI, P., Boniver, J., Delvenne, P., & Hubert, P. (September 2010). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. Cell Symposium on Inflammation and Disease, Lisbonne, Portugal.

Herfs, M. (2010). Etude des mécanismes moléculaires et cellulaires responsable de la métaplasie épidermoïde cervicale et de sa susceptibilité au développement cancéreux [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315179

Herfs, M. (2010). Etude des mécanismes moléculaires et cellulaires responsables de la métaplasie épidermoïde cervicale et de sa susceptibilité au développement cancéreux [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/203010

Herman, L., Hubert, P., Herfs, M., Kustermans, G., Henrotin, Y., Bousarghin, L., Boniver, J., & Delvenne, P. (2010). The L1 major capsid protein of HPV16 differentially modulates APC trafficking according to the vaccination or natural infection context. European Journal of Immunology, 40 (11), 3075-84. doi:10.1002/eji.201040571
Peer Reviewed verified by ORBi

Demoulin, S., Somja, J., Herfs, M., Delvenne, P., & Hubert, P. (2010). Implication of plasmacytoid dendritic cells in the malignant transformation of cervical epithelial metaplasia [Poster presentation]. GIGA Cancer Day, Liège, Belgium.

Theelen, W., Speel, E.-J. M., Herfs, M., Reijans, M., Simons, G., Meulemans, E. V., Baldewijns, M. M., Ramaekers, F. C. S., Somja, J., Delvenne, P., & Hopman, A. H. N. (2010). Increase in viral load, viral integration, and gain of telomerase genes during uterine cervical carcinogenesis can be simultaneously assessed by the HPV 16/18 MLPA-assay. American Journal of Pathology, 177 (4), 2022-33. doi:10.2353/ajpath.2010.090901
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Herfs, M., Hubert, P., Suarez-Carmona, M., Reschner, A., Saussez, S., Berx, G., Savagner, P., Boniver, J., & Delvenne, P. (2010). Regulation of p63 Isoforms by Snail and Slug Transcription Factors in Human Squamous Cell Carcinoma. American Journal of Pathology, 176 (4), 1941-1949. doi:10.2353/ajpath.2010.090804
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Herfs, M., Hubert, P., & Delvenne, P. (June 2009). Epithelial metaplasia: adult stem cell reprogramming and (pre)neoplastic transformation mediated by inflammation? Trends in Molecular Medicine, 15 (6), 245-253. doi:10.1016/j.molmed.2009.04.002
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Herfs, M., Herman, L., Hubert, P., Minner, F., Arafa, M. M. M., Roncarati, P., Henrotin, Y., Boniver, J., & Delvenne, P. (April 2009). High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells. Cancer Immunology, Immunotherapy, 58 (4), 603-614. doi:10.1007/s00262-008-0584-4
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Caberg, J.-H., Hubert, P., Herman, L., Herfs, M., Roncarati, P., Boniver, J., & Delvenne, P. (January 2009). Increased migration of Langerhans cells in response to HPV16 E6 and E7 oncogene silencing: role of CCL20. Cancer Immunology, Immunotherapy, 58 (1), 39-47. doi:10.1007/s00262-008-0522-5
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Caberg, J.-H., Hubert, P., Begon, D., Herfs, M., Roncarati, P., Boniver, J., & Delvenne, P. (July 2008). Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes. Carcinogenesis, 29 (7), 1441-7. doi:10.1093/carcin/bgn145
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Herfs, M. (May 2008). Cervical epithelial metaplaisia and HPV infection [Paper presentation]. University of Reims Champagne-Ardenne, Reims, France.

Herfs, M., Hubert, P., Kholod, N., Caberg, J.-H., Gilles, C., Berx, G., Savagner, P., Boniver, J., & Delvenne, P. (May 2008). Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression. American Journal of Pathology, 172 (5), 1391-402. doi:10.2353/ajpath.2008.071004
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Nikkels, A., Delvenne, P., Herfs, M., & Pierard, G. (2008). Occult Herpes Simplex Virus Colonization of Bullous Dermatitides. American Journal of Clinical Dermatology. doi:10.2165/00128071-200809030-00004
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Herfs, M. (2007). TGF-B1 reduces the immunosurveillance of the cervical transformation zone by affecting the E-cadherin mediated interactions between Langerhans cells and metaplastic keratinocytes [Specialised master, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/203012

Delvenne, P., Goffin, F., Kridelka, F., Arafa, M., Carberg, J., Herfs, M., Herman, L., Hubert, P., Jacobs, N., Kholod, N., Foidart, J.-M., & Boniver, J. (2007). La cancer du col utérin: une infection par HPV qui tourne mal. Tempo Médical.

Delvenne, P., Herman, L., Kholod, N., Caberg, J.-H., Herfs, M., Boniver, J., Jacobs, N., & Hubert, P. (2007). Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix. Molecular and Cellular Endocrinology, 264 (1-2), 1-5. doi:10.1016/j.mce.2006.10.014
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Delvenne, P., Goffin, F., Kridelka, F., Arafa, M., Caberg, J.-H., Herfs, M., Herman, L., Hubert, P., Jacobs, N., Kholod, N., Boniver, J., & Foidart, J.-M. (2007). Le cancer du col de l'utérus: du virus au traitement. Revue Médicale de Liège, 62(S1), 2-6.

Herfs, M. (2006). Rôle des cofacteurs immunitaires dans la séquence métaplasie-dysplasie-cancer [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/203011

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