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Huyghebaert Loreen

Département de pharmacie > Chimie médicale

See author's contact details
Main Referenced Co-authors
Cavalier, Etienne  (43)
Le Goff, Caroline  (43)
Peeters, Stéphanie  (29)
Demeuse, Justine  (23)
Grifnée, Elodie  (20)
Main Referenced Keywords
LC-MS/MS (10); Clinical Biochemistry (3); General Medicine (3); Mass spectrometry (3); vitamin D (3);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (1)
MARE - Centre Interfacultaire de Recherches en Océanologie - ULiège [BE] (1)
Main Referenced Disciplines
Laboratory medicine & medical technology (38)
Endocrinology, metabolism & nutrition (4)
Environmental sciences & ecology (2)
Chemistry (2)

Publications (total 46)

The most downloaded
276 downloads
LE GOFF, C., Fabregat Cabello, N., Huyghebaert, L., PEETERS, S., VROONEN, L., & CAVALIER, E. (13 June 2017). Validation of a 13 steroids panel with the Chromsystem kit by LC-MS/MS [Poster presentation]. Euromedlab IFCC, Athenes, Greece. https://hdl.handle.net/2268/213668

The most cited

40 citations (Scopus®)

Fabregat Cabello, N., Farre Segura, J., Huyghebaert, L., PEETERS, S., LE GOFF, C., Souberbielle, J.-C., & Cavalier, E. (2017). A fast and simple method for simultaneous measurements of 25(OH)D, 24,25(OH)2D and the Vitamin D Metabolite Ratio (VMR) in serum samples by LC-MS/MS. Clinica Chimica Acta. doi:10.1016/j.cca.2017.08.024 https://hdl.handle.net/2268/214328

Huyghebaert, L., Massonnet, P., Grifnée, E., Demeuse, J., Peeters, S., Dubrowski, T., Schoumacher, M., Cavalier, E., & Le Goff, C. (31 January 2024). Simultaneous detection and quantification of gastrin 17 and 34 sulfated and non-sulfated forms by LC-MS/MS in human plasma [Poster presentation]. CIRM Day 2024, Liège, Belgium.
Peer reviewed

Demeuse, J.* , Huyghebaert, L.* , Determe, W., Schoumacher, M., Grifnée, E., Massonnet, P., Dubrowski, T., Rechchad, M., Farre Segura, J., Peeters, S., Cavalier, E.* , & Le Goff, C.*. (2023). Development and validation of an LC-MS/MS method for the simultaneous quantitation of angiotensin (1-7), (1-8), (1-9) and (1-10) in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 123943. doi:10.1016/j.jchromb.2023.123943
Peer reviewed
* These authors have contributed equally to this work.

Huyghebaert, L., Massonnet, P., Grifnée, E., Demeuse, J., Dubrowski, T., Schoumacher, M., Peeters, S., Cavalier, E., & Le Goff, C. (17 November 2023). Simultaneous detection and quantification of gastrin 17 and 34 sulfated and non-sulfated forms by LC-MS/MS in human plasma [Poster presentation]. RBSLM, Bruxelles, Belgium.
Editorial reviewed

Demeuse, J., Massonnet, P., Schoumacher, M., Grifnée, E., Huyghebaert, L., Dubrowski, T., Peeters, S., Le Goff, C., & Cavalier, E. (25 August 2023). Innovative workflow for the identification of cathepsin K cleavage sites in type I collagen. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1228, 123864. doi:10.1016/j.jchromb.2023.123864
Peer Reviewed verified by ORBi

Huyghebaert, L. (17 May 2023). From small to large molecules by mass spectrometry: the different projects of the Clinical Chemistry department. Gastrins [Paper presentation]. CIRM Seminar, Liège, Belgium.

Massonnet, P., Grifnee, E., Farre Segura, J., Demeuse, J., Huyghebaert, L., Dubrowski, T., Dufour, P., Schoumacher, M., Peeters, S., Le Goff, C., & Cavalier, E. (03 May 2023). Concise review on the combined use of immunocapture, mass spectrometry and liquid chromatography for clinical applications. Clinical Chemistry and Laboratory Medicine, 0 (0). doi:10.1515/cclm-2023-0253
Peer Reviewed verified by ORBi

Demeuse, J., Calaprice, C., Huyghebaert, L., Rechchad, M., Peeters, S., Cavalier, E., & Le Goff, C. (2023). Development and Validation of an Ultrasensitive LC-MS/MS Method for the Quantification of Melatonin in Human Saliva. Journal of the American Society for Mass Spectrometry. doi:10.1021/jasms.3c00021
Peer Reviewed verified by ORBi

Cavalier, E., Fraser, C. G., Bhattoa, H. P., Heijboer, A. C., Makris, K., Vasikaran, S., Huyghebaert, L., Peeters, S., Le Goff, C., Herrmann, M., Carobene, A., & IFCC-IOF Committee for Bone Metabolisma. (31 March 2023). Analytical performance specifications for the measurement uncertainty of 24,25-dihydroxyvitamin D examinations. Clinical Chemistry and Laboratory Medicine, 0 (0). doi:10.1515/cclm-2023-0176
Peer Reviewed verified by ORBi

Massonnet, P., Henri, L.-A., Farre Segura, J., Peeters, S., Grifnee, E., Demeuse, J., Huyghebaert, L., Dubrowski, T., Schoumacher, M., Le Goff, C., & Cavalier, E. (01 February 2023). Characterization of intact Parathyroid hormone and its fragments by Liquid Chromatography coupled to High-Resolution Mass Spectrometry [Poster presentation]. CIRM day 2023.
Peer reviewed

Demeuse, J., Massonnet, P., Grifnee, E., Huyghebaert, L., Schoumacher, M., Dubrowski, T., Determe, W., Peeters, S., Le Goff, C., & Cavalier, E. (01 February 2023). Towards B-CTX characterization [Paper presentation]. CIRM day 2023, Liège, Belgium.
Peer reviewed

Huyghebaert, L., Demeuse, J., Determe, W., Farre Segura, J., Peeters, S., Grifnee, E., Massonnet, P., Dubrowski, T., Schoumacher, M., Cavalier, E., & Le Goff, C. (01 February 2023). Simultaneous detection and quantification of angiotensin 1-7, 1-8, 1-9 and 1-10 by LC-MS/MS in human plasma [Poster presentation]. CIRM Day 2023, Liège, Belgium.
Peer reviewed

Grifnee, E., Blistein, F., Demeuse, J., Huyghebaert, L., Massonnet, P., Schoumacher, M., Dubrowski, T., Peeters, S., Cavalier, E., & Le Goff, C. (01 February 2023). Development of a liquid chromatography - tandem mass spectrometry method for the quantitation of Oxytocin [Poster presentation]. CIRM Day.

Demeuse, J., Huyghebaert, L., Determe, W., Schoumacher, M., Grifnée, E., Massonnet, P., Peeters, S., Le Goff, C., & Cavalier, E. (2023). Validation of a lc-ms/ms method for the simultaneous quantitation of angiotensin (1-7), (1-8), (1-9) and (1-10) [Poster presentation]. RBSLM.
Editorial reviewed

Massonnet, P., Huyghebaert, L., Grifnée, E., Demeuse, J., Determe, W., Schoumacher, M., Dubrowski, T., Cavalier, E., & Le Goff, C. (2023). Development of a quantitation method for parathormone related protein (PTHrp) by LC-MS/MS [Poster presentation]. 2023 Annual RBSLM Meeting, Bruxelles, Belgium.
Peer reviewed

Grifnée, E., Blistein, F., Demeuse, J., Huyghebaert, L., Massonnet, P., Schoumacher, M., Dubrowski, T., Peeters, S., Cavalier, E., & Le Goff, C. (2023). Development of a liquid chromatography-tandem mass spectrometry method for the quantitation of Oxytocin [Poster presentation]. Euromedlab 2023.

Demeuse, J., Determe, W., Grifnée, E., Schoumacher, M., Huyghebaert, L., Massonnet, P., Dubrowski, T., Peeters, S., Le Goff, C., & Cavalier, E. (2023). Caractérisation des espèces de CTX dans le plasma humain [Paper presentation]. Journée Grand Est - AFSEP.

Demeuse, J., Massonnet, P., Determe, W., Schoumacher, M., Grifnée, E., Huyghebaert, L., Peeters, S., Le Goff, C., & Cavalier, E. (2023). Towards β-CTX Quantitation Standarization : First steps of characterization [Poster presentation]. Euromedlab 2023, Rome, Italy.
Peer reviewed

Huyghebaert, L., Demeuse, J., Grifnee, E., Massonnet, P., Farre Segura, J., Peeters, S., Le Goff, C., & Cavalier, E. (August 2022). Simultaneous detection and quantification of angiotensin I, II, 1-7 and 1-9 by LC-MS/MS in human plasma [Poster presentation]. International Mass Spectrometry Conference (IMSC) 2022, Maastricht, Netherlands.
Peer reviewed

Demeuse, J., Grifnee, E., Massonnet, P., Huyghebaert, L., Peeters, S., Le Goff, C., & Cavalier, E. (August 2022). Mass spectrometry evaluation of type I collagen in-situ digestion in biological matrices [Poster presentation]. IMSC 2022, Maastricht, Netherlands.

Massonnet, P., Peeters, S., Grifnee, E., Demeuse, J., Huyghebaert, L., Farre Segura, J., Delanaye, P., Le Goff, C., & Cavalier, E. (August 2022). Iohexol quantitation and possible degradation kinetics in human urine using mass spectrometry coupled to liquid chromatography (LC) [Poster presentation]. International Mass Spectrometry Conference (IMSC) 2022, Maastricht, Netherlands.
Peer reviewed

MASSONNET, P., GRIFNEE, E., Demeuse, J., Huyghebaert, L., PEETERS, S., Farre Segura, J., LE GOFF, C., & CAVALIER, E. (03 May 2022). Workshop on principles in proteomics: MALDI Imaging [Paper presentation]. Belgian Proteomics Association Conference (BePAc) 2022: A proteomics perspective on protein function in space and time.

Demeuse, J., Calaprice, C., Huyghebaert, L., Rechchad, M., CAVALIER, E., & LE GOFF, C. (April 2022). Validation of an ultra-sensitive method for the quantification of melatonin in human saliva [Poster presentation]. EuroMedLab 2021 Munich, Munich, Germany.

Huyghebaert, L., Demeuse, J., Farre Segura, J., Peeters, S., Grifnée, E., Vanden Broeck, N., COLLARD, G., Dufour, P., Massonnet, P., Dubrowski, T., Cavalier, E., & Le Goff, C. (2022). VALIDATION OF A LC-MS/MS METHOD FOR THE QUANTITATION OF PLASMA RENINE ACTIVITY (PRA) IN HUMAN [Paper presentation]. RBSLM Congress.
Peer reviewed

Massonnet, P., Peeters, S., Grifnée, E., Demeuse, J., Huyghebaert, L., Dubrowski, T., Dufour, P., Farre Segura, J., Delanaye, P., Le Goff, C., & Cavalier, E. (2022). QUANTIFICATION AND POSSIBLE DEGRADATION KINETICS OF IOHEXOL IN HUMAN FLUIDS USING MASS SPECTROMETRY COUPLED TO LIQUID CHROMATOGRAPHY [Paper presentation]. RBSLM Congress.
Peer reviewed

Demeuse, J., CALAPRICE, C., Huyghebaert, L., Rechchad, M., Le Goff, C., & Cavalier, E. (16 September 2021). TROUBLESHOOTING : Development of a LC-MS/MS method for trace-level analysis of salivary melatonin [Paper presentation]. MSACL 2021 EU.

LADANG, A., ROUSSELLE, O., Huyghebaert, L., BEKAERT, A.-C., KOVACS, S., Le Goff, C., & Cavalier, E. (2020). Parathormone, bone alkaline phosphatase and 25-hydroxyvitamin D status in a large cohort of 1200 children and teenagers. Acta Clinica Belgica, 1-6. doi:10.1080/17843286.2020.1769285
Peer Reviewed verified by ORBi

Cavalier, E., Huyghebaert, L., ROUSSELLE, O., BEKAERT, A.-C., KOVACS, S., VRANKEN, L., PEETERS, S., Le Goff, C., & LADANG, A. (2020). Simultaneous measurement of 25(OH)-vitamin D and 24,25(OH)2-vitamin D to define cut-offs for CYP24A1 mutation and vitamin D deficiency in a population of 1200 young subjects. Clinical Chemistry and Laboratory Medicine, 58 (2), 197-201. doi:10.1515/cclm-2019-0996
Peer Reviewed verified by ORBi

LE GOFF, C., NIX, C., Huyghebaert, L., & CAVALIER, E. (15 November 2019). COMPARATIVE EVALUATION OF 4 DIFFERENT BD VACUTAINER® BLOOD COLLECTION TUBES TO STUDY THE STABILITY OF 15 STEROIDS [Poster presentation]. RBSLM.

VRANKEN, L., FONTAINE, C., VALDES SOCIN, H. G., LUKAS, P., LE GOFF, C., Huyghebaert, L., & CAVALIER, E. (15 November 2019). Impact of Metformin on vitamin B12 status [Poster presentation]. Annual Meeting of the Royal Belgian Society of Laboratory Medicine 2019.

LE GOFF, C., VRANKEN, L., PEETERS, S., GENDEBIEN, A.-S., Huyghebaert, L., Fabregat Cabello, N., & CAVALIER, E. (21 May 2019). Determination of serum androstanediol glucuronide reference range intervals in a cohort of heathy Belgian subjects [Poster presentation]. Euromedlab IFCC.

LE GOFF, C., Zelzer, S., Huyghebaert, L., Farre Segura, J., Fabregat Cabello, N., Hermann, M., & CAVALIER, E. (21 May 2019). Method comparison of the 24,25(OH)2D3 measurement with two different LCMS/MS assays [Poster presentation]. Euromedlab, Barcelone, Spain.

VRANKEN, L., FONTAINE, C., LUKAS, P., LE GOFF, C., Huyghebaert, L., CAVALIER, E., & VALDES SOCIN, H. G. (May 2019). Evaluation of Metformin impact on vitamin B12 status [Poster presentation]. 23rd IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine “EuroMedLab” Barcelona 2019, Barcelone, Spain.

LADANG, A., ROUSSELLE, O., Huyghebaert, L., BEKAERT, A.-C., KOVACS, S., LE GOFF, C., & CAVALIER, E. (May 2019). 24,25(OH)2D AS A MARKER OF VITAMIN D DEFICIENCY IN CHILDREN: A RETROSPECTIVE [Poster presentation]. Euromedlab 2019.

LADANG, A., ROUSSELLE, O., Huyghebaert, L., BEKAERT, A.-C., KOVACS, S., LE GOFF, C., & CAVALIER, E. (May 2019). EVALUATION OF PARATHORMONE AND 25-HYDROXYVITAMIN D STATUS IN A LARGE [Poster presentation]. Euromedlab 2019.

Le Goff, C., VRANKEN, L., Peeters, S., GENDEBIEN, A.-S., Huyghebaert, L., Fabregat Cabello, N., & Cavalier, E. (2019). Determination of serum androstanediol glucuronide reference range intervals in a cohort of healthy Belgian subject [Poster presentation]. Euromedlab 2019, Barcelone, Spain.
Peer reviewed

Le Goff, C., Zelzer, S., Huyghebaert, L., Farre Segura, J., Fabregat Cabello, N., Hermann, M., & Cavalier, E. (2019). Method comparison of the 24,25(OH)2D3 measurement with two different LC-MS/MS assays [Poster presentation]. Euromedlab 2019, Barcelone, Spain.
Peer reviewed

Fabregat Cabello, N., DARIMONT, P., Huyghebaert, L., Reynier, P., Annweiler, C., Milea, D., Le Goff, C., & Cavalier, E. (2019). Liquid chromatography-tandem mass spectrometry for monitoring Vitamin D hydroxymetabolites in human aqueous humor. Analytical Methods, 11 (41), 5282-5288. doi:10.1039/c9ay01896d
Peer Reviewed verified by ORBi

Fabregat Cabello, N., Farre Segura, J., Huyghebaert, L., PEETERS, S., LE GOFF, C., & Cavalier, E. (September 2017). A fast and simple method for simultaneous measurements of 25(OH)D, 24,25(OH)2D and the Vitamin D Metabolite Ratio (VMR) in serum samples by LC-MS/MS (powerpoint) [Paper presentation]. MSACL, Salzburg, Austria.

Fabregat Cabello, N., Farre Segura, J., Huyghebaert, L., PEETERS, S., LE GOFF, C., Souberbielle, J.-C., & Cavalier, E. (2017). A fast and simple method for simultaneous measurements of 25(OH)D, 24,25(OH)2D and the Vitamin D Metabolite Ratio (VMR) in serum samples by LC-MS/MS. Clinica Chimica Acta. doi:10.1016/j.cca.2017.08.024
Peer Reviewed verified by ORBi

Pinzone, M., Acquarone, M., Huyghebaert, L., Sturaro, N., Michel, L., Siebert, U., & Das, K. (01 August 2017). Carbon, Nitrogen and Sulphur isotopic fractionation in captive juvenile hooded seal (Cystophora cristata): application for diet analysis. Rapid Communications in Mass Spectrometry, 31, 1720-1728. doi:10.1002/rcm.7955
Peer Reviewed verified by ORBi

LE GOFF, C., Fabregat Cabello, N., Huyghebaert, L., PEETERS, S., VROONEN, L., & CAVALIER, E. (13 June 2017). Validation of a 13 steroids panel with the Chromsystem kit by LC-MS/MS [Poster presentation]. Euromedlab IFCC, Athenes, Greece.

LE GOFF, C., Fabregat Cabello, N., Huyghebaert, L., PEETERS, S., VROONEN, L., & CAVALIER, E. (2017). Establishment of reference values for 6 six steroids in serum. Clinical Chemistry and Laboratory Medicine.
Peer Reviewed verified by ORBi

LE GOFF, C., Fabregat Cabello, N., Huyghebaert, L., PEETERS, S., VROONEN, L., & CAVALIER, E. (2017). Reference interval determination for serum and urine aldosterone for healthy Belgian population. Clinical Chemistry and Laboratory Medicine.
Peer Reviewed verified by ORBi

Le Goff, C., Huyghebaert, L., Peeters, S., Vroonen, L., & Cavalier, E. (2017). Establishment of reference values for 6 six steroids in serum by LC-MS/MS [Poster presentation]. Mass Spectrometry and Advances in Clinical Lab, Salzburg, Austria.
Peer reviewed

Fabregat Cabello, N., Huyghebaert, L., Gonzalez Antuña, A., LE GOFF, C., & Cavalier, E. (September 2016). Development of a new methodology for the simultaneous determination of cholecalciferol and 24,25(OH)2D3 by LC-MS/MS [Paper presentation]. MSACL, Salzbourg, Austria.

Huyghebaert, L., Acquarone, M., Pinzone, M., Jauniaux, T., Siebert, U., Sturaro, N., Michel, L., & Das, K. (08 October 2015). Stable carbon, nitrogen and sulfur isotopic fractionation between diet and tissue of captive hooded seals, Cystophora cristata: implications for dietary reconstruction of wild individuals [Poster presentation]. Zoology 2015, Amsterdam, Netherlands.

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