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Grifnée Elodie

Département de pharmacie > Chimie médicale

See author's contact details
ORCID
0009-0004-7745-1640
Main Referenced Co-authors
Cavalier, Etienne  (28)
Le Goff, Caroline  (28)
Demeuse, Justine  (25)
Huyghebaert, Loreen  (25)
Massonnet, Philippe  (25)
Main Referenced Keywords
LC-MS/MS (4); mass spectrometry (3); Clinical Biochemistry (2); General Medicine (2); limited digestion (2);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège (1)
Laboratoire de Spectrométrie de Masse (1)
Laboratoire de spectrométrie de masse (1)
Main Referenced Disciplines
Laboratory medicine & medical technology (23)
Chemistry (20)
Endocrinology, metabolism & nutrition (2)
Urology & nephrology (1)

Publications (total 45)

The most downloaded
133 downloads
Grifnee, E., Kune, C., Delvaux, C., Quinton, L., Far, J., Mazzucchelli, G., & De Pauw, E. (2022). Label-free higher order structure and dynamic investigation method of proteins in solution using an enzymatic reactor coupled to electrospray high-resolution mass spectrometry. Journal of the American Society for Mass Spectrometry. doi:10.1021/jasms.1c00274 https://hdl.handle.net/2268/295376

The most cited

38 citations (OpenAlex)

Morsa, D., Baiwir, D., La Rocca, R., Zimmerman, T. A., Hanozin, E., Grifnée, E., Longuespée, R., Meuwis, M.-A., Smargiasso, N., De Pauw, E., & Mazzucchelli, G. (2019). Multi-Enzymatic Limited Digestion: The Next-Generation Sequencing for Proteomics? Journal of Proteome Research. doi:10.1021/acs.jproteome.9b00044 https://hdl.handle.net/2268/235837

Gillet, V., BREVERS, E., Grifnée, E., Rechchad, M., Cavalier, E., Millet, G., & Le Goff, C. (18 May 2025). Inflammatory biomarkers variations in an ultra-endurance event : A case study of the Tor des Géants [Poster presentation]. Euromedlab 2025, Bruxelles, Belgium.

Gillet, V., Campas, M., Pinsart, A., Grifnée, E., Schoumacher, M., De Tullio, P., Cavalier, E., Millet, G., & Le Goff, C. (18 May 2025). Metabolic Adaptations and Performance in Ultra-Endurance: A Case Study of the Tor des Géants [Poster presentation]. Euromedlab 2025, Bruxelles, Belgium.

Grifnée, E., Mackowiak, A., Demeuse, J., Schoumacher, M., Huyghebaert, L., Determe, W., Dubrowski, T., Massonnet, P., Peeters, S., Scantamburlo, G., Cavalier, E., & Le Goff, C. (27 February 2025). Development and validation of a highly-sensitive, quantitative LC-MS/MS assay to evaluate plasma oxytocin. Journal of Mass Spectrometry and Advances in the Clinical Lab, 36, 19-28. doi:10.1016/j.jmsacl.2025.02.002
Editorial reviewed

Determe, W., Hauge, S. C., Demeuse, J., Massonnet, P., Grifnée, E., Huyghebaert, L., Dubrowski, T., Schoumacher, M., Peeters, S., Le Goff, C., Evenepoel, P., Hansen, D., & Cavalier, E. (02 December 2024). Osteocalcin: A bone protein with multiple endocrine functions. Clinica Chimica Acta, 567, 120067. doi:10.1016/j.cca.2024.120067
Peer Reviewed verified by ORBi

Huyghebaert, L., Massonnet, P., Grifnée, E., Demeuse, J., Dubrowski, T., Peeters, S., Cavalier, E., & Le Goff, C. (14 November 2024). Development of a new clinical diagnostic tool for cardiovascular risk assessment by LC-MS/MS [Poster presentation]. Royal Belgian Society of Laboratory Medicine, Dolce la Hulpe, Brussels, Belgium.
Peer reviewed

Demeuse, J., DETERME, W., Grifnée, E., Massonnet, P., Schoumacher, M., Huyghebeart, L., Dubrowski, T., Peeters, S., Le Goff, C., & Cavalier, E. (2024). Characterization of Trivalently Crosslinked C-Terminal Telopeptide of Type I Collagen (CTX) Species in Human Plasma and Serum Using High-Resolution Mass Spectrometry. Proteomics, 202400027. doi:10.1002/pmic.202400027
Peer Reviewed verified by ORBi

Grifnée, E., Kune, C., Delvaux, C., Tilmant, T., Quinton, L., Matagne, A., Mazzucchelli, G., Far, J., & De Pauw, E. (2024). Investigation of Structure-Stabilizing Elements in Proteins by Ion Mobility Mass Spectrometry and Collision-Induced Unfolding. Journal of the American Society for Mass Spectrometry. doi:10.1021/jasms.3c00398
Peer Reviewed verified by ORBi

Demeuse, J., Determe, W., Grifnée, E., Schoumacher, M., Massonnet, P., Huyghebaert, L., Dubrowski, T., Peeters, S., Le Goff, C., & Cavalier, E. (18 April 2024). Characterization of the Crosslinked Carboxy-Terminal Telopeptide of Type I Collagen in Human Plasma and Serum Using High-Resolution Mass Spectrometry [Poster presentation]. OARSI 2024, Vienne, Austria.
Editorial reviewed

Huyghebaert, L., Massonnet, P., Grifnée, E., Demeuse, J., Peeters, S., Dubrowski, T., Schoumacher, M., Cavalier, E., & Le Goff, C. (31 January 2024). Simultaneous detection and quantification of gastrin 17 and 34 sulfated and non-sulfated forms by LC-MS/MS in human plasma [Poster presentation]. CIRM Day 2024, Liège, Belgium.
Peer reviewed

Demeuse, J.* , Huyghebaert, L.* , Determe, W., Schoumacher, M., Grifnée, E., Massonnet, P., Dubrowski, T., Rechchad, M., Farre Segura, J., Peeters, S., Cavalier, E.* , & Le Goff, C.*. (2024). Development and validation of an LC-MS/MS method for the simultaneous quantitation of angiotensin (1-7), (1-8), (1-9) and (1-10) in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 123943. doi:10.1016/j.jchromb.2023.123943
Peer reviewed
* These authors have contributed equally to this work.

Huyghebaert, L., Massonnet, P., Grifnée, E., Demeuse, J., Dubrowski, T., Schoumacher, M., Peeters, S., Cavalier, E., & Le Goff, C. (17 November 2023). Simultaneous detection and quantification of gastrin 17 and 34 sulfated and non-sulfated forms by LC-MS/MS in human plasma [Poster presentation]. RBSLM, Bruxelles, Belgium.
Editorial reviewed

Demeuse, J., Massonnet, P., Schoumacher, M., Grifnée, E., Huyghebaert, L., Dubrowski, T., Peeters, S., Le Goff, C., & Cavalier, E. (25 August 2023). Innovative workflow for the identification of cathepsin K cleavage sites in type I collagen. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1228, 123864. doi:10.1016/j.jchromb.2023.123864
Peer Reviewed verified by ORBi

Massonnet, P., Grifnee, E., Farre Segura, J., Demeuse, J., Huyghebaert, L., Dubrowski, T., Dufour, P., Schoumacher, M., Peeters, S., Le Goff, C., & Cavalier, E. (03 May 2023). Concise review on the combined use of immunocapture, mass spectrometry and liquid chromatography for clinical applications. Clinical Chemistry and Laboratory Medicine, 0 (0). doi:10.1515/cclm-2023-0253
Peer Reviewed verified by ORBi

Demeuse, J., Massonnet, P., Grifnee, E., Huyghebaert, L., Schoumacher, M., Dubrowski, T., Determe, W., Peeters, S., Le Goff, C., & Cavalier, E. (01 February 2023). Towards B-CTX characterization [Paper presentation]. CIRM day 2023, Liège, Belgium.
Peer reviewed

Massonnet, P., Henri, L.-A., Farre Segura, J., Peeters, S., Grifnee, E., Demeuse, J., Huyghebaert, L., Dubrowski, T., Schoumacher, M., Le Goff, C., & Cavalier, E. (01 February 2023). Characterization of intact Parathyroid hormone and its fragments by Liquid Chromatography coupled to High-Resolution Mass Spectrometry [Poster presentation]. CIRM day 2023.
Peer reviewed

Grifnee, E., Blistein, F., Demeuse, J., Huyghebaert, L., Massonnet, P., Schoumacher, M., Dubrowski, T., Peeters, S., Cavalier, E., & Le Goff, C. (01 February 2023). Development of a liquid chromatography - tandem mass spectrometry method for the quantitation of Oxytocin [Poster presentation]. CIRM Day.

Huyghebaert, L., Demeuse, J., Determe, W., Farre Segura, J., Peeters, S., Grifnee, E., Massonnet, P., Dubrowski, T., Schoumacher, M., Cavalier, E., & Le Goff, C. (01 February 2023). Simultaneous detection and quantification of angiotensin 1-7, 1-8, 1-9 and 1-10 by LC-MS/MS in human plasma [Poster presentation]. CIRM Day 2023, Liège, Belgium.
Peer reviewed

Demeuse, J., Huyghebaert, L., Determe, W., Schoumacher, M., Grifnée, E., Massonnet, P., Peeters, S., Le Goff, C., & Cavalier, E. (2023). Validation of a lc-ms/ms method for the simultaneous quantitation of angiotensin (1-7), (1-8), (1-9) and (1-10) [Poster presentation]. RBSLM.
Editorial reviewed

Grifnée, E., Blistein, F., Demeuse, J., Huyghebaert, L., Massonnet, P., Schoumacher, M., Dubrowski, T., Peeters, S., Cavalier, E., & Le Goff, C. (2023). Development of a liquid chromatography-tandem mass spectrometry method for the quantitation of Oxytocin [Poster presentation]. Euromedlab 2023.

Massonnet, P., Huyghebaert, L., Grifnée, E., Demeuse, J., Determe, W., Schoumacher, M., Dubrowski, T., Cavalier, E., & Le Goff, C. (2023). Development of a quantitation method for parathormone related protein (PTHrp) by LC-MS/MS [Poster presentation]. 2023 Annual RBSLM Meeting, Bruxelles, Belgium.
Peer reviewed

Demeuse, J., Massonnet, P., Determe, W., Schoumacher, M., Grifnée, E., Huyghebaert, L., Peeters, S., Le Goff, C., & Cavalier, E. (2023). Towards β-CTX Quantitation Standarization : First steps of characterization [Poster presentation]. Euromedlab 2023, Rome, Italy.
Peer reviewed

Demeuse, J., Determe, W., Grifnée, E., Schoumacher, M., Huyghebaert, L., Massonnet, P., Dubrowski, T., Peeters, S., Le Goff, C., & Cavalier, E. (2023). Caractérisation des espèces de CTX dans le plasma humain [Paper presentation]. Journée Grand Est - AFSEP.

Dufour, P., Grifnee, E., BREVERS, E., Paquot, N., Le Goff, C., Cavalier, E., & Ladang, A. (18 November 2022). LABORATORY EXPLORATION OF A VERY HIGH LEVEL OF INSULIN MEASURED IN A LONG-STANDING TYPE 1 DIABETIC PATIENT [Poster presentation]. 2022 Annual RBSLM Meeting.
Peer reviewed

Grifnee, E., Kune, C., Delvaux, C., Quinton, L., Matagne, A., Mazzucchelli, G., Far, J., & De Pauw, E. (29 August 2022). Investigation of structure-stabilizing elements in proteins by ion mobility mass spectrometry and collision-induced unfolding [Poster presentation]. IMSC.
Peer reviewed

Massonnet, P., Peeters, S., Grifnee, E., Demeuse, J., Huyghebaert, L., Farre Segura, J., Delanaye, P., Le Goff, C., & Cavalier, E. (August 2022). Iohexol quantitation and possible degradation kinetics in human urine using mass spectrometry coupled to liquid chromatography (LC) [Poster presentation]. International Mass Spectrometry Conference (IMSC) 2022, Maastricht, Netherlands.
Peer reviewed

Huyghebaert, L., Demeuse, J., Grifnee, E., Massonnet, P., Farre Segura, J., Peeters, S., Le Goff, C., & Cavalier, E. (August 2022). Simultaneous detection and quantification of angiotensin I, II, 1-7 and 1-9 by LC-MS/MS in human plasma [Poster presentation]. International Mass Spectrometry Conference (IMSC) 2022, Maastricht, Netherlands.
Peer reviewed

Demeuse, J., Grifnee, E., Massonnet, P., Huyghebaert, L., Peeters, S., Le Goff, C., & Cavalier, E. (August 2022). Mass spectrometry evaluation of type I collagen in-situ digestion in biological matrices [Poster presentation]. IMSC 2022, Maastricht, Netherlands.

MASSONNET, P., GRIFNEE, E., Demeuse, J., Huyghebaert, L., PEETERS, S., Farre Segura, J., LE GOFF, C., & CAVALIER, E. (03 May 2022). Workshop on principles in proteomics: MALDI Imaging [Paper presentation]. Belgian Proteomics Association Conference (BePAc) 2022: A proteomics perspective on protein function in space and time.

Huyghebaert, L., Demeuse, J., Farre Segura, J., Peeters, S., Grifnée, E., Vanden Broeck, N., COLLARD, G., Dufour, P., Massonnet, P., Dubrowski, T., Cavalier, E., & Le Goff, C. (2022). VALIDATION OF A LC-MS/MS METHOD FOR THE QUANTITATION OF PLASMA RENINE ACTIVITY (PRA) IN HUMAN [Paper presentation]. RBSLM Congress.
Peer reviewed

Grifnee, E., Kune, C., Delvaux, C., Quinton, L., Far, J., Mazzucchelli, G., & De Pauw, E. (2022). Label-free higher order structure and dynamic investigation method of proteins in solution using an enzymatic reactor coupled to electrospray high-resolution mass spectrometry. Journal of the American Society for Mass Spectrometry. doi:10.1021/jasms.1c00274
Peer Reviewed verified by ORBi

Massonnet, P., Peeters, S., Grifnée, E., Demeuse, J., Huyghebaert, L., Dubrowski, T., Dufour, P., Farre Segura, J., Delanaye, P., Le Goff, C., & Cavalier, E. (2022). QUANTIFICATION AND POSSIBLE DEGRADATION KINETICS OF IOHEXOL IN HUMAN FLUIDS USING MASS SPECTROMETRY COUPLED TO LIQUID CHROMATOGRAPHY [Paper presentation]. RBSLM Congress.
Peer reviewed

Grifnée, E. (2021). Development of an enzymatic reactor based workflow for structural characterization of proteins [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/266018

Grifnée, E., Quinton, L., La Rocca, R., Mazzucchelli, G., & De Pauw, E. (2019). Structural characterization of proteins by using enzymatic reactor [Poster presentation]. NVMS-BSMS.

Morsa, D., Baiwir, D., La Rocca, R., Zimmerman, T. A., Hanozin, E., Grifnée, E., Longuespée, R., Meuwis, M.-A., Smargiasso, N., De Pauw, E., & Mazzucchelli, G. (2019). Multi-Enzymatic Limited Digestion: The Next-Generation Sequencing for Proteomics? Journal of Proteome Research. doi:10.1021/acs.jproteome.9b00044
Peer Reviewed verified by ORBi

Hanozin, E., Grifnée, E., Gattuso, H., Matagne, A., Morsa, D., & De Pauw, E. (2019). Benchmarking IM-MS gas-phase data based on cross-linking strategies [Paper presentation]. 4th NVMS-BSMS Conference on Mass Spectrometry - Rolduc 2019.

Hanozin, E., Grifnée, E., Gattuso, H., Matagne, A., Morsa, D., & De Pauw, E. (2019). Covalent Cross-Linking as an Enabler for Structural Mass Spectrometry. Analytical Chemistry. doi:10.1021/acs.analchem.9b02491
Peer Reviewed verified by ORBi

Hanozin, E., Grifnée, E., Morsa, D., Matagne, A., & De Pauw, E. (June 2018). Can we correlate ion mobility mass spectrometry data with native solution structures? A crosslinking approach [Poster presentation]. 66th ASMS Conference on Mass Spectrometry and Allied Topics.

Hanozin, E., Grifnée, E., Morsa, D., & De Pauw, E. (April 2018). Can we correlate ion mobility mass spectrometry data with native solution structures? A crosslinking approach [Poster presentation]. 10th Isolated Biomolecules Biomolecular Interactions (IBBI).

Grifnée, E., Hanozin, E., Smargiasso, N., Quinton, L., Mazzucchelli, G., & De Pauw, E. (2018). Structural characterization of proteins based on a homemade enzymatic reactor [Poster presentation]. BSMS.

Grifnée, E., Quinton, L., & De Pauw, E. (March 2017). Structural characterization of proteins by using enzymatic reactor [Paper presentation]. COST Héraklion.

Grifnée, E. (2017). Structural characterization of protein using an enzymatic reactor [Poster presentation]. 65 ème congrès de la société américaine de spectrométrie de masse.

Baumans, F., Grifnée, E. (Other coll.), Hage, C. (Other coll.), Quinton, L. (Other coll.), Sinz, A. (Other coll.), & De Pauw, E. (Other coll.). (05 September 2016). Contribution of Cross-linking and Ion-mobility for the study of protein and complex structures [Poster presentation]. International School of Biophysics, Split, Rogoznica, Zadar, Sali, Croatia.

Grifnée, E., Hanozin, E., Baumans, F., Quinton, L., & De Pauw, E. (September 2016). Contribution of cross-linking and ion-mobility for the study of proteins and protein complexes [Poster presentation]. JFSM.

Grifnée, E., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (2015). Study of residual protein structure during enzymatic digestion by ion mobility mass spectrometry [Poster presentation]. SSP Halle.

Grifnée, E., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (November 2014). Structural characterization of protein using an enzymatic reactor [Poster presentation]. SSP 2014.

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