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Lekeux Gilles


Main Referenced Co-authors
Galleni, Moreno  (16)
Hanikenne, Marc  (16)
Laurent, Clémentine  (13)
Damblon, Christian  (9)
Bosman, Bernard  (3)
Main Referenced Keywords
P-type ATPase (2); Arabidopsis (1); AtHMA4 (1); Cadmium (Cd) (1); Cd-binding (1);
Main Referenced Unit & Research Centers
CIP - Centre d'Ingénierie des Protéines - ULiège [BE] (1)
Laboratoire de Biophysique Moléculaire aux Interfaces (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (17)
Phytobiology (plant sciences, forestry, mycology...) (2)

Publications (total 19)

The most downloaded
90 downloads
Laurent, C.* , Lekeux, G.* , Ukuwela, A. A., Xiao, Z., Charlier, J.-B., Bosman, B., Carnol, M., Motte, P., Damblon, C., Galleni, M., & Hanikenne, M. (2016). Metal binding to the N-terminal cytoplasmic domain of the PIB ATPase HMA4 is required for metal transport in Arabidopsis. Plant Molecular Biology, 90, 453-466. doi:10.1007/s11103-016-0429-z https://hdl.handle.net/2268/190665
The most cited
19 citations (Scopus®)
Lekeux, G.* , Crowet, J.-M.* , Nouet, C., Joris, M., Jadoul, A., Bosman, B., Carnol, M., Motte, P., Lins, L., Galleni, M., & Hanikenne, M. (2019). Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase. Journal of Experimental Botany, 70, 329-341. doi:10.1093/jxb/ery353 https://hdl.handle.net/2268/228501

Ceasar, S. A., Lekeux, G., Motte, P., Xiao, Z., Galleni, M., & Hanikenne, M. (2020). di-Cysteine Residues of the Arabidopsis thaliana HMA4 C-Terminus Are Only Partially Required for Cadmium Transport. Frontiers in Plant Science, 11, 560. doi:10.3389/fpls.2020.00560
Peer Reviewed verified by ORBi

Lekeux, G.* , Crowet, J.-M.* , Nouet, C., Joris, M., Jadoul, A., Bosman, B., Carnol, M., Motte, P., Lins, L., Galleni, M., & Hanikenne, M. (2019). Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase. Journal of Experimental Botany, 70, 329-341. doi:10.1093/jxb/ery353
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Lekeux, G. (2018). Functional characterization of Arabidopsis HMA4 P-type ATPases. Unpublished doctoral thesis, ULiège - Université de Liège.
Jury: Galleni, M. (Promotor), Hanikenne, M. (Promotor), Charlier, P., González-Guerrero, M., Verbruggen, N., Remacle, C., Delaplace, P., ... Feller, G.

Lekeux, G., Laurent, C., Joris, M., Jadoul, A., Jiang, D., Bosman, B., Carnol, M., Motte, P., Xiao, Z., Galleni, M., & Hanikenne, M. (2018). di-Cysteine motifs in the C-terminus of plant HMA4 proteins confer nanomolar affinity for zinc and are essential for HMA4 function in vivo. Journal of Experimental Botany, 69 (22), 5547-5560. doi:10.1093/jxb/ery311
Peer Reviewed verified by ORBi

Lekeux, G., Laurent, C., Xiao, Z., Crowet, J.-M., Lins, L., Hanikenne, M., & Galleni, M. (24 July 2017). Functional and structural characterisation of the Arabidopsis thaliana HMA4 protein. Poster session presented at Cell Biology of Metals - Godon Research Conference, West Dover, United States.

Lekeux, G. (24 May 2016). Functional and structural characterization of the P1B ATPase HMA4 involved in metal hyperaccumulation in Arabidopsis halleri. Paper presented at AIP meeting of the iPROS network.

Laurent, C.* , Lekeux, G.* , Ukuwela, A. A., Xiao, Z., Charlier, J.-B., Bosman, B., Carnol, M., Motte, P., Damblon, C., Galleni, M., & Hanikenne, M. (2016). Metal binding to the N-terminal cytoplasmic domain of the PIB ATPase HMA4 is required for metal transport in Arabidopsis. Plant Molecular Biology, 90, 453-466. doi:10.1007/s11103-016-0429-z
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Lekeux, G., Laurent, C., Hanikenne, M., & Galleni, M. (03 December 2015). Functional and structural characterization of the Arabidopsis thaliana HMA4 protein. Poster session presented at IAP 7/44 Meeting - Integrative Protein Science: from small molecules to complex biological systems – iPros, Leuven, Belgium.

Crowet, J.-M., Lekeux, G., Hanikenne, M., Brasseur, R., Galleni, M., & Lins, L. (03 December 2015). Molecular modelling of the metal ATPase HMA4 from Arabidopsis halleri. Poster session presented at IAP 7/44 Meeting: Integrative Protein Science: from small molecules to complex biological systems - iPros.

Lekeux, G., Laurent, C., Galleni, M., & Hanikenne, M. (08 June 2015). Functional and structural analysis of the Arabidopsis thaliana HMA4 protein. Poster session presented at AIP meeting 2015.

Laurent, C., Lekeux, G., Damblon, C., Hanikenne, M., & Galleni, M. (08 June 2015). Functional and structural characterization of the Arabidopsis halleri HMA4 N-terminal domain. Poster session presented at IAP meeting.

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (14 November 2014). Structural and functional characterization of the Arabidopsis halleri HMA4 protein. Poster session presented at Journée doctorale Namur "Industrial researches in structural biological chemistry".

Lekeux, G., Laurent, C., Damblon, C., Galleni, M., & Hanikenne, M. (09 September 2014). Structural and functional analysis of the HMA4 protein. Poster session presented at Summer school-Chemistry of metals in biological systems.

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (15 May 2014). Structural and functional analysis of the Arabidopsis halleri HMA4 protein. Poster session presented at Bioforum 2014.

Lekeux, G., Laurent, C., Damblon, C., Galleni, M., & Hanikenne, M. (06 May 2014). Structural and functional study of the Arabidopsis halleri HMA4 protein. Poster session presented at PhytoSYSTEMS day.

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (15 November 2013). Structural and functional analysis of the Arabidopsis halleri HMA4 N-terminal domain. Poster session presented at SFMBBM Doctoral School.

Lekeux, G. (03 October 2013). Molecular mechanisms of metal hyperaccumulation in plants. Paper presented at IAP meeting "Integrative Protein Science: from small molecules to complex biological systems".

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (18 April 2013). Structural and functional study of the Arabidopsis halleri HMA4 N-terminal domain. Poster session presented at Bioforum 2013, Liège, Belgium.

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (26 February 2013). Structural and functional characterization of the Arabidopsis halleri HMA4 N-terminal domain. Poster session presented at IAP meeting: "Integrative Protein Science: from small molecules to complex biological systems".

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