Stäubert, C., Wozniak, M., Dupuis, N., Laschet, C., Pillaiyar, T., & Hanson, J. (2022). Superconserved receptors expressed in the brain: Expression, function, motifs and evolution of an orphan receptor family. Pharmacology & Therapeutics, 108217. doi:10.1016/j.pharmthera.2022.108217 Peer reviewed |
Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (21 September 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Nature Communications, 11 (1), 4752. doi:10.1038/s41467-020-18500-x Peer Reviewed verified by ORBi |
Laschet, C., Dupuis, N., Geubelle, P., Abboud, D., & Hanson, J. (September 2017). Targeted mutagenesis of orphan GPCRs of the SREB family [Poster presentation]. International Symposium on GPCRs and G-proteins, Bonn, Germany. |
Dupuis, N., Laschet, C., Franssen, D., Martyna, S., Gilissen, J., Geubelle, P., Soni, A., Parent, A.-S., Pirotte, B., Chevigné, A., Twizere, J.-C., & Hanson, J. (01 June 2017). Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment. Molecular Pharmacology, 91 (6), 595-608. doi:10.1124/mol.116.107714 Peer Reviewed verified by ORBi |
Dupuis, N. (2017). Identification of chemical probes and signaling pathways for the orphan GPCR GPR27 [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/314819 |
Geubelle, P., Gilissen, J., Dilly, S., POMA, L., Dupuis, N., Laschet, C., Abboud, D., Inoue, A., Jouret, F., Pirotte, B., & Hanson, J. (May 2017). Identification and pharmacological characterization of succinate receptor agonists. British Journal of Pharmacology, 174 (9), 796-808. doi:10.1111/bph.13738 Peer Reviewed verified by ORBi |
Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (May 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation [Poster presentation]. 19th European Congress of Endocrinology, Lisbon, Portugal. |
Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (April 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation [Poster presentation]. Belgian Society of Physiology and Pharmacology, Bruxelles, Belgium. |
Abboud, D., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., & Hanson, J. (November 2016). GPR101 orphan GPCR: a novel cause of growth hormone deregulation [Poster presentation]. Fifth annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med), Tours, France. |
Franssen, D., Dupuis, N., Lopez Rodriguez, D., GERARD, A., Hanson, J., Bourguignon, J.-P., & Parent, A.-S. (October 2016). Identification of an orphan GPCR, GPR151, as a target of BPA exposure and a potential actor of the GnRH network [Paper presentation]. 41e colloque de la société de Neuroendocrinologie. |
Dupuis, N., Franssen, D., Laschet, C., Geubelle, P., Soni, A., Abboud, D., Twizere, J.-C., Pirotte, B., & Hanson, J. (26 September 2016). Small molecule ligands for the orphan GPR27 [Poster presentation]. GLISTEN meeting 2016 in Prague. |
Laschet, C., Dupuis, N., Soni, A., Geubelle, P., Abboud, D., & Hanson, J. (September 2016). Targeted mutagenesis of orphan GPCRs of the SREB family [Poster presentation]. GLISTEN 2016 in Prague. |
Szpakowska, M., Dupuis, N., Baragli, A., Counson, M., Hanson, J., Piette, J., & Chevigné, A. (15 August 2016). Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7. Biochemical Pharmacology, 114, 14-21. doi:10.1016/j.bcp.2016.05.012 Peer Reviewed verified by ORBi |
Dupuis, N., Gilissen, J., Derj, A., Soni, A., Geubelle, P., Laschet, C., Piron, C., Twizere, J.-C., Pirotte, B., & Hanson, J. (25 January 2016). Identification of small molecule ligands for the orphan GPCR GPR27 [Poster presentation]. GIGA-DAY 2016. |
Laschet, C., Dupuis, N., Derj, A., Gilissen, J., Geubelle, P., Soni, A., Pirotte, B., & Hanson, J. (25 January 2016). Targeted and random mutagenesis of orphan GPCRs of the SREB family [Poster presentation]. GIGA-Day. |
Geubelle, P., Gilissen, J., Dupuis, N., Derj, A., Laschet, C., Soni, A., Pirotte, B., & Hanson, J. (05 June 2015). Identification, Design and Evaluation of Pharmacological tools for the orphan GPCR GPR22 [Paper presentation]. 29ème Journées Franco-Belge de Pharmacochimie, Spa, Belgium. |
Geubelle, P., Gilissen, J., Dupuis, N., Derj, A., Laschet, C., Soni, A., Pirotte, B., & Hanson, J. (27 January 2015). Identification, Design and Evaluation of Pharmacological tools for the orphan GPCR GPR22 [Poster presentation]. 2015 GIGA Day: Current Advances in Medical Genetics and Genomics, Liège, Belgium. |
Dupuis, N., Gilissen, J., Derj, A., Laschet, C., Geubelle, P., Soni, A., Piron, C., Twizere, J.-C., Pirotte, B., & Hanson, J. (27 January 2015). ßarrestin coupling of the orphan GPCR GPR27 [Poster presentation]. GIGA-day 2015, Liege, Belgium. |
Franssen, D., Dupuis, N., GERARD, A., HENNUY, B., Hanson, J., Bourguignon, J.-P., & Parent, A.-S. (2015). Disruption of Gonadotropin-Releasing Hormone secretion in peripubertal female rat after early postnatal exposure to Bisphenol A and involvement of GPR151, a potential new Gonadotropin-Releasing Hormone regulator [Poster presentation]. Society for Neurosciences (SFN). |
Franssen, D., Dupuis, N., GERARD, A., HENNUY, B., Hanson, J., Parent, A.-S., & Bourguignon, J.-P. (2015). Alteration of the neuroendocrine control of puberty after early postnatal exposure to Bisphenol A and involvement of a potential new regulator of GnRH network GPR151 [Poster presentation]. BSN-SNE joint meeting. |
Gilissen, J., Geubelle, P., Dupuis, N., Laschet, C., Pirotte, B., & Hanson, J. (2015). Forskolin-free cAMP assay for Gi-coupled receptors. Biochemical Pharmacology. doi:10.1016/j.bcp.2015.09.010 Peer Reviewed verified by ORBi |
Gilissen, J., Dupuis, N., Derj, A., Soni, A., Dilly, S., Pirotte, B., & Hanson, J. (21 November 2014). Identification of modulators for SUCNR1 by screening of a SOSA library with a bioluminescent cAMP assay [Paper presentation]. MedChem 2014, Braine-L'alleud (UCB), Belgium. |
Geubelle, P., Gilissen, J., Dupuis, N., Derj, A., Laschet, C., Soni, A., Pirotte, B., & Hanson, J. (21 November 2014). Identification, Design and Evaluation of Pharmacological tools for the orphan GPCR GPR22 [Poster presentation]. MedChem 2014 New Vistas in GPCR Research: the Dawn of an Exciting Drug Discovery Era?, Braine-L'Alleud, Belgium. |
Laschet, C., Dupuis, N., Derj, A., Gilissen, J., Geubelle, P., Soni, A., Pirotte, B., & Hanson, J. (21 November 2014). Understanding the pharmacology and signaling pathways of the orphan G protein coupled receptor GPR85/SREB2 [Poster presentation]. Annual one-day meeting on medicinal chemistry. |
Dupuis, N., Gilissen, J., Derj, A., Laschet, C., Geubelle, P., Soni, A., Twizere, J.-C., Pirotte, B., & Hanson, J. (October 2014). Identifying ligands for orphan receptors: test screening of a SOSA library with a complementation assay for orphan GPCR GPR27 [Poster presentation]. third annual meeting of the GDR3545, Montpellier, France. |
Dupuis, N., Gilissen, J., Derj, A., Soni, A., Twizere, J.-C., Pirotte, B., & Hanson, J. (16 July 2014). Ligand-independent Identification of orphan GPCR Signaling pathways [Paper presentation]. World Congress of basic & clinical Pharmacology, Cape Town, South Africa. |
Dupuis, N., Gilissen, J., Derj, A., Soni, A., Twizere, J.-C., Pirotte, B., & Hanson, J. (05 June 2014). LIGAND-INDEPENDENT IDENTIFICATION OF ORPHAN GPCR ARRESTIN BINDING [Poster presentation]. 23èmes Journées franco-belges de Pharmacochimie, Metz, France. |
Dupuis, N., Gilissen, J., Derj, A., Soni, A., Twizere, J.-C., Pirotte, B., & Hanson, J. (04 April 2014). Ligand-independent Identification of orphan GPR27 Signaling pathways [Poster presentation]. Physphar 2014. |
Derj, A., Dupuis, N., Gilissen, J., Soni, A., Pirotte, B., Chevigné, A., & Hanson, J. (27 January 2014). Unraveling the signaling and dimerization properties of CXCR3 isoforms and their interplay with CXCR7 in the context of glioblastoma pathology [Poster presentation]. GIGA Day 2014, Liège, Belgium. |
Dupuis, N., Gilissen, J., Derj, A., Soni, A., Twizere, J.-C., Pirotte, B., & Hanson, J. (14 January 2014). Development of a luciferase complementation assay for ligand screening on orphan GPCR GPR27 [Poster presentation]. GIGA-DAY 2014. |
Dupuis, N., Gilissen, J., Twizere, J.-C., Pirotte, B., & Hanson, J. (18 October 2013). Development of an original β-arrestin complementation assay for orphan GPCR GPR27(SREB1) ligand and signaling pathways determination [Poster presentation]. Autumn Meeting of Belgian Society of Physiology and Pharmacology. |
Dupuis, N., Gilissen, J., Pirotte, B., & Hanson, J. (06 June 2013). Identification of chemical probes and signaling pathways for the orphan GPCR GPR27 [Poster presentation]. 27èmes Journées franco-belges de Pharmacochimie & 21èmes Conférences européennes du GP2A, Lille, France. |
Dupuis, N., Gilissen, J., Pirotte, B., & Hanson, J. (28 January 2013). Chemical probes and signaling pathways for the orphan GPCR GPR27 [Poster presentation]. Giga-Day 2013. |
Gilissen, J., Pirotte, B., Hanson, J., & Dupuis, N. (Other coll.). (28 January 2013). Pharmacological evaluation of succinic acid receptor (SUCNR1) modulators [Poster presentation]. GIGA Day 2013. |
Gilissen, J., Pirotte, B., Hanson, J., & Dupuis, N. (Other coll.). (30 November 2012). Synthesis and pharmacological evaluation of succinic acid receptor (SUCNR1) small molecule modulators [Poster presentation]. MedChem 2012 - From Rapid Dissociation to Irreversible Inhibition - Optimisation of Drug-Target Residence Time. |