Profil

Jacques Nicolas

See author's contact details
Main Referenced Co-authors
Oury, Cécile  (11)
Lancellotti, Patrizio  (9)
Musumeci, Lucia  (7)
Goffin, Eric  (5)
Pirotte, Bernard  (5)
Main Referenced Keywords
daptomycin (2); Infectious Diseases (2); MRSA (2); Pharmacology (2); Pharmacology (medical) (2);
Main Referenced Disciplines
Cardiovascular & respiratory systems (5)
Microbiology (5)
Immunology & infectious disease (2)
General & internal medicine (1)
Pharmacy, pharmacology & toxicology (1)

Publications (total 12)

The most downloaded
1406 downloads
Goffin, E., Jacques, N., Musumeci, L., Nchimi Longang, A., Oury, C., Lancellotti, P., & Pirotte, B. (2020). Synthesis of ticagrelor analogues belonging to 1,2,3-triazolo[4,5-d]pyrimidines and study of their antiplatelet and antibacterial activity. European Journal of Medicinal Chemistry, 208, 112767. doi:10.1016/j.ejmech.2020.112767 https://hdl.handle.net/2268/251915

The most cited

1100 citations (OpenAlex)

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x https://hdl.handle.net/2268/260539

Leeten, K., Jacques, N., Esquembre, L. A., Schneider, D. C., Straetener, J., Henriksen, C., MUSUMECI, L., Putters, F., Ferreira Melo, S., Sánchez-López, E., Giera, M., Penoy, N., Piel, G., Verlaine, O., Amoroso, A., Joris, B., Slavetinsky, C. J., Goffin, E., Pirotte, B., ... Oury, C. (2024). Ticagrelor alters the membrane of Staphylococcus aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance. MBio, 0132224. doi:10.1128/mbio.01322-24
Peer Reviewed verified by ORBi

Nielsen, T. K., Petersen, I. B., Xu, L., Barbuti, M. D., Mebus, V., Justh, A., Alqarzaee, A. A., Jacques, N., Oury, C., Thomas, V., Kjos, M., Henriksen, C., & Frees, D. (05 June 2024). The Spx stress regulator confers high-level β-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 68 (6), 0033524. doi:10.1128/aac.00335-24
Peer Reviewed verified by ORBi

Oury, C., Lancellotti, P., Leeten, K., & Jacques, N. (14 December 2023). N-alkyl-2-substituted ATP analogues for use as antibacterial agent.

Xu, L., Henriksen, C., Mebus, V., Guérillot, R., Petersen, A., Jacques, N., Jiang, J.-H., Derks, R. J. E., Sánchez-López, E., Giera, M., Leeten, K., Stinear, T. P., Oury, C., Howden, B. P., Peleg, A. Y., & Frees, D. (2023). A Clinically Selected Staphylococcus aureus clpP Mutant Survives Daptomycin Treatment by Reducing Binding of the Antibiotic and Adapting a Rod-Shaped Morphology. Antimicrobial Agents and Chemotherapy, 0032823. doi:10.1128/aac.00328-23
Peer Reviewed verified by ORBi

Lancellotti, P., Aqil, A., MUSUMECI, L., Jacques, N., Ditkowski, B., Debuisson, M., Thiry, M., Dupont, J., Gougnard, A., Sandersen, C., CHERAMY-BIEN, J.-P., Sakalihasan, N., Nchimi Longang, A., Detrembleur, C., Jérôme, C., & Oury, C. (2023). Bioactive surface coating for preventing mechanical heart valve thrombosis. Journal of Thrombosis and Haemostasis. doi:10.1016/j.jtha.2023.05.004
Peer reviewed

Oury, C., Meyers, S., Jacques, N., Leeten, K., Jiang, Z., MUSUMECI, L., Lox, M., Debuisson, M., Goffin, E., Pirotte, B., Delvenne, P., Nchimi Longang, A., Hubert, C., Heptia, M., Hubert, P., Kuijpers, M. J. E., Vanassche, T., Martinod, K., Verhamme, P., & Lancellotti, P. (2023). Protective Effect of Ticagrelor Against Infective Endocarditis Induced by Virulent Staphylococcus aureus in Mice. JACC: Basic to Translational Science. doi:10.1016/j.jacbts.2023.02.003
Peer Reviewed verified by ORBi

LANCELLOTTI, P., Oury, C., Pirotte, B., MUSUMECI, L., Jacques, N., & Goffin, E. (23 September 2021). Preparation of pyrimidine derivatives for prevention and treatment of Gram-negative bacterial infection, contamination and fouling.

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x
Peer Reviewed verified by ORBi

Oury, C., Pirotte, B., MUSUMECI, L., Jacques, N., Goffin, E., & LANCELLOTTI, P. (22 October 2020). New pyrimidine derivatives for prevention and treatment of gram negative bacterial infection, contamination and fouling.

LANCELLOTTI, P., Jacques, N., & Oury, C. (17 April 2020). Tackling prosthetic heart valve-related deterioration: Liège translational cardiovascular research programme. EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 15 (17), 1485-1487. doi:10.4244/EIJV15I17A272
Peer Reviewed verified by ORBi

Goffin, E., Jacques, N., Musumeci, L., Nchimi Longang, A., Oury, C., Lancellotti, P., & Pirotte, B. (2020). Synthesis of ticagrelor analogues belonging to 1,2,3-triazolo[4,5-d]pyrimidines and study of their antiplatelet and antibacterial activity. European Journal of Medicinal Chemistry, 208, 112767. doi:10.1016/j.ejmech.2020.112767
Peer Reviewed verified by ORBi

Oury, C., Musumeci, L., Jacques, N., & LANCELLOTTI, P. (2019). Activité antibiotique de l'antiplaquettaire ticagrelor : une nouvelle piste contre l'antibiorésistance. Vaisseaux, Coeur, Poumons, 24 (7), 8-13.
Peer reviewed

Contact ORBi