De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Kempen, I., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (26 November 1999). Enantiomeric resolution of pirlindole at the preparative scale: derivatization and chromatographic methods [Poster presentation]. Chirality: Impact in Drug Design and Development, Braine l'Alleud, Belgium. |
De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M. H., Kempen, I., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (26 November 1999). Enantiomeric resolution of pirlindole at the preparative scale: derivatization and chromatographic methods [Poster presentation]. Chirality: Impact in Drug Design and Development, Braine l’Alleud, Belgium. |
![]() ![]() | Khelili, S., De Tullio, P., Lebrun, P., Fillet, M., Antoine, M.-H., Ouedraogo, R., Dupont, L., Fontaine, J., Felekidis, A., Leclerc, G., Delarge, J., & Pirotte, B. (1999). Preparation and pharmacological evaluation of the R- and S-enantiomers of 3-(2’-butylamino)-4H- and 3-(3’-methyl-2’-butylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxide, two tissue selective ATP-sensitive potassium channel openers. Bioorganic and Medicinal Chemistry, 7 (8), 1513-1520. doi:10.1016/S0968-0896(99)00082-6 ![]() |
![]() ![]() | De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1999). Effective resolution of racemic pirlindole at the preparative scale. Chirality, 11, 261-266. doi:10.1002/(SICI)1520-636X(1999)11:4<261::AID-CHIR1>3.0.CO;2-S ![]() |
De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (September 1998). Effective resolution of racemic pirlindole at the preparative scale: derivatization method and absolute configuration [Poster presentation]. XVth EFMC International Symposium on Medicinal Chemistry. |
De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (September 1998). Preparative resolution of racemic pirlindole: chromatographic methods and determination of the absolute configuration [Poster presentation]. Fourth European Congress of Pharmaceutical Sciences, Milan, Italy. |
De Tullio, P., Ceccato, A., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (16 January 1998). Séparation énantiomérique du pirlindole à l’échelle préparative [Poster presentation]. Journées Jeunes Chercheurs, Paris, France. |
![]() ![]() | De Tullio, P., Felekidis, A., Pirotte, B., Liégeois, J.-F., Stachow, M., Delarge, J., Ceccato, A., Hubert, P., Crommen, J., & Geczy, J. (1998). First preparative enantiomer resolution of pirlindole, a potent antidepressant drug. Helvetica Chimica Acta, 81, 539-547. doi:10.1002/hlca.19980810307 ![]() |
Pirotte, B., De Tullio, P., Stachow, M., Felekidis, A., Liégeois, J.-F., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Tentatives de synthèse énantiosélective des isomères R et S du pirlindole. Journal de Pharmacie de Belgique, 53, 60. ![]() |
De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Résolution préparative du pirlindole. Journal de Pharmacie de Belgique, 53, 55. ![]() |
De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Preparative resolution of racemic pirlindole: chromatographic methods and determination of the absolute configuration. European Journal of Pharmaceutical Sciences, suppl.1, 37. ![]() |
Pirotte, B., De Tullio, P., Stachow, M., Felekidis, A., Liégeois, J.-F., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (May 1997). Tentatives de synthèse énantiosélective des isomères R et S du pirlindole [Poster presentation]. Onzièmes Journées Franco-Belges de Pharmacochimie, Bruxelles, Belgium. |
De Tullio, P., Felekidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Ceccato, A., Hubert, P., Crommen, J., Cegzy, J., & Delarge, J. (May 1997). Résolution préparative du pirlindole [Poster presentation]. Onzièmes Journées Franco-Belges de Pharmacochimie, Bruxelles, Belgium. |
![]() ![]() | Felekidis, A., Goblet-Stachow, M., Liégeois, J.-F., Pirotte, B., Delarge, J., Demonceau, A., Fontaine, M., Noels, A. F., Chizhevsky, I. T., Zinevich, T. V., Bregadze, V. I., Dolgushin, F. M., Yanovsky, A. I., & Struchkov, Y. T. (1997). Ligand effects in the hydrogenation of methacycline to doxycycline and epi-doxycycline catalysed by rhodium complexes. Molecular structure of the key catalyst [closo-3,3-(η2,3-C7H7CH2)-3,1,2-Rh C2B9H11]. Journal of Organometallic Chemistry, 536-537, 405-412. doi:10.1016/S0022-328X(96)06743-5 ![]() |
Felekidis, A., Goblet-Stachow, M., Liégeois, J.-F., Pirotte, B., Delarge, J., Demonceau, A., Fontaine, M., Noels, A. F., Chizhevsky, I. T., Zinevich, T. V., & Bregadze, V. I. (1995). Influence de la nature des ligands sur l'hydrogenation de la méthacycline en doxycycline et en épi-doxycycline par des complexes du Rhodium. Journal de Pharmacie de Belgique, 50, 232. ![]() |
Felekidis, A., Goblet-Stachow, M., Liégeois, J.-F., Pirotte, B., Delarge, J., Demonceau, A., Fontaine, M., Noels, A. F., Chizhevsky, I. T., Zinevich, T. V., & Bregadze, V. I. (May 1994). Influence de la nature des ligands sur l'hydrogénation de la méthacycline en doxycycline et en épi-doxycycline par des complexes du Rhodium [Poster presentation]. Huitièmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium. |
Demonceau, A., Fontaine, M., Noels, A. F., Felekidis, A., Pirotte, B., Delarge, J., Chizhevsky, I. T., Zinevich, T. V., Pisareva, I. V., & Bregadze, V. I. (December 1993). Ligand effects in the hydrogenation of methacycline to doxycycline and epi-doxycycline catalysed by rhodium complexes. Molecular structure of the key catalyst [closo-3,3-(η2,3-C7H7CH2)-3,1,2-Rh C2B9H11] [Poster presentation]. Contact Group Meeting Organic Synthesis NFWO-FNRS, De Haan, Belgium. |
Fontaine, M., Demonceau, A., Noels, A. F., Felekidis, A., Pirotte, B., Delarge, J., Chizhevsky, I. T., Zinevich, T. V., Pisareva, I. V., & Bregadze, V. I. (July 1993). Stereoselective hydrogenation of methacycline to doxycycline catalysed by rhodium-carborane complexes [Poster presentation]. Fifth International Conference on the Chemistry of the Platinum Group Metals, United Kingdom. |
![]() ![]() | Pirotte, B., Felekidis, A., Fontaine, M., Demonceau, A., Noels, A., Delarge, J., Chizhevsky, I. T., Zinevich, T. V., Pisareva, I. V., & Bregadze, V. I. (1993). Stereoselective hydrogenation of methacycline to doxycycline catalysed by rhodium-carborane complexes. Tetrahedron Letters, 34, 1471-1474. doi:10.1016/S0040-4039(00)60321-0 ![]() |
Fontaine, M., Demonceau, A., Noëls, A. F., Felekidis, A., Pirotte, B., Delarge, J., Chizhevsky, I. T., Zinevich, T. V., Pisareva, I. V., & Bregadze, V. I. (November 1992). Stereoselective hydrogenation of methacycline to doxycycline catalysed by rhodium-carborane complexes [Poster presentation]. Organic Synthesis Meeting, De Haan, Belgium. |
Felekidis, A., Pirotte, B., & Demonceau, A. (08 May 1992). Application of high performance liquid chromatography to the determination of the optimized reaction conditions giving stereoselective hydrogenation of methacycline to doxycycline [Poster presentation]. 4th international symposium on drug analysis, Liège, Belgium. |
Felekidis, A., & Pirotte, B. (08 March 1991). Application of high performance liquid chromatography to the evaluation of the stereoselective hydrogenation of 6-demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline [Poster presentation]. Chiralité et Analyse, Bruxelles, Belgium. |
Pirotte, B., & Felekidis, A. (March 1991). Evaluation of the stereoselective homogeneous catalytic hydrogenation of methacycline into doxycycline using different zerovalent and monovalent rhodium catalysts [Paper presentation]. Troisième Forum des Sciences Pharmaceutiques, Houffalize, Belgium. |
Felekidis, A., & Pirotte, B. (1991). Evaluation of the stereoselective homogeneous catalytic hydrogenation of methacycline into doxycycline using different zerovalent and monovalent rhodium catalysts. Journal de Pharmacie de Belgique, 46, 147. ![]() |