Profil

Ledoux Allison

Département de pharmacie > Pharmacognosie

Département de pharmacie

CIRM

See author's contact details
Main Referenced Co-authors
Frederich, Michel  (72)
Jansen, Olivia  (35)
Coelho Cristino Mamede, Lucia Cristina  (20)
Desdemoustier, Pauline  (16)
Hamann, Carla  (13)
Main Referenced Keywords
Malaria (9); malaria (7); Metabolomics (7); Strychnos (7); Loganiaceae (4);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (9)
Center of Interdisciplinary Research on Medicines (1)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (68)
Phytobiology (plant sciences, forestry, mycology...) (4)
Chemistry (4)
Biochemistry, biophysics & molecular biology (3)
Microbiology (3)

Publications (total 86)

The most downloaded
366 downloads
Fall, F., Coelho Cristino Mamede, L. C., Schioppa, L., Ledoux, A., De Tullio, P., Michels, P., Frederich, M., & Quetin-Leclercq, J. (19 March 2022). Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery. Metabolomics, 18 (4), 20. doi:10.1007/s11306-022-01880-0 https://hdl.handle.net/2268/291222

The most cited

33 citations (Scopus®)

Ledoux, A., St-Gelais, A., Cieckiewicz, E., Jansen, O., Bordignon, A., Illien, B., Di Giovanni, N., Marvilliers, A., Hoareau, F., Pendeville-Samain, H., Leclercq, J., & Frederich, M. (2017). Antimalarial Activities of Alkyl Cyclohexenone Derivatives Isolated from the Leaves of Poupartia borbonica. Journal of Natural Products, 80 (6), 1750-1757. doi:10.1021/acs.jnatprod.6b01019 https://hdl.handle.net/2268/211315

Ledoux, A. (2024). "Madame, quand viens-tu nous parler des pays pauvres?!" Comprendre et déconstruire les stéréotypes, expliqué pour les petits de 4 à 6 ans [Paper presentation]. Animation à l'école Saint Jean-Marie, Sart-Tilman.

Coelho Cristino Mamede, L. C., Fall, F., Schoumacher, M., Ledoux, A., Bugli, C., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (February 2024). Comparison of extraction methods in vitro Plasmodium falciparum: A 1 H NMR and LC-MS joined approach. Biochemical and Biophysical Research Communications, 703, 149684. doi:10.1016/j.bbrc.2024.149684
Peer reviewed

Hamann, C., Jansen, O., Djabrailova, D., Sacre, P.-Y., Bafort, F., Ledoux, A., & Frederich, M. (31 January 2024). The crucial role of drying conditions in hemp flowers: Effects on cannabinoid decarboxylation and terpene profile in extracts [Paper presentation]. CIRM day 2024, Liège, Belgium.
Peer reviewed

Koopmans, S. J., Binnendijk, G., Ledoux, A., Choi, Y. H., Mes, J. J., Guan, X., Molist, F., Thị Minh, T. P., & van der Wielen, N. (2024). Momordica charantia fruit reduces plasma fructosamine whereas stems and leaves increase plasma insulin in adult mildly diabetic obese Göttingen Minipigs. PLoS ONE, 19 (3), 0298163. doi:10.1371/journal.pone.0298163
Peer Reviewed verified by ORBi

Le Loarer, A., Dufossé, L., Bign, J., Frederich, M., Ledoux, A., Fouillaud, M., Gauvin-Bialecki, A., Coppola, D., Sala, G., & Khalil, Z. (28 December 2023). OSMAC Method to Assess Impact of Culture Parameters on Metabolomic Diversity and Biological Activity of Marine-Derived Actinobacteria. Marine Drugs, 22 (1), 23. doi:10.3390/md22010023
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Rangel, G. W., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Frederich, M., & Llinás, M. (17 July 2023). Profiling plants with antimalarial blood stage activity using metabolomics: an added dimension to drug discovery [Paper presentation]. 6e Symposium International de l’AFERP.

Leka, K., Hoste, A., Xin, R., Hamann, C., Garigliany, M.-M., & Ledoux, A. (06 July 2023). Exploring the potential of traditional Chinese medicines for antiviral therapy [Poster presentation]. 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Dublin, Ireland.

Leka, K., Colson, T., Lesenfants, C., Zhou, D., Garigliany, M.-M., Ledoux, A., & Francotte, P. (01 July 2023). HALOGENATION OF ETHANOL EXTRACT FROM PAEONIA SUFFRUTICOSA: EXPLORING PROMISING PATHWAYS FOR ANTI-SARS-COV-2 MEDICATION DEVELOPMENT [Poster presentation]. 6e Symposium International AFERP – 17 au 19 juillet 2023 –, Orsay, France.
Peer reviewed

Ledoux, A., Leka, K., Jansen, O., Bonnet, O., Hamann, C., Angenot, L., Garigliany, M.-M., & Frederich, M. (July 2023). Exploring the antiviral activity of flavonoids from Strychnos variabilis leaves against SARS-CoV-2. Planta Medica, 89 (14), 1421.
Peer Reviewed verified by ORBi

Hamann, C., Jullien, K., Jansen, O., Bafort, F., Libault, A., Marotte, A., Leka, K., Ledoux, A., & Frederich, M. (July 2023). Comparison of cannabinoids and terpenes profiles of different hemp extracts obtained from Felina and Santhica varieties cultivated in Belgium [Poster presentation]. 71th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Dublin, Ireland.
Editorial reviewed

Lahngong, M. S., Loe, G. E., Jansen, O., Coelho Cristino Mamede, L. C., Ledoux, A., Noukimi, S. F., Abenwie, S. N., Ghogomu, S. M., Souopgui, J., Robert, A., Demeyer, K., & Frederich, M. (29 April 2023). Secondary Metabolites Isolated from Artemisia afra and Artemisia annua and Their Anti-Malarial, Anti-Inflammatory and Immunomodulating Properties—Pharmacokinetics and Pharmacodynamics: A Review. Metabolites, 13 (5), 613. doi:10.3390/metabo13050613
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., W. Rangel, G., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Llinás, M., & Frederich, M. (25 April 2023). Profiling plant extracts with antimalarial bloodstage activity using metabolomics [Poster presentation]. WORLD MALARIA DAY SYMPOSIUM: Blood Stage Malaria | Staving Off the Firestorm, Baltimore, United States.

Gerometta, E., Herbette, G., Garayev, E., Marvilliers, A., Naubron, J.-V., Di Giorgio, C., Campos, P.-E., Clerc, P., Ledoux, A., Frederich, M., Baghdikian, B., Grondin, I., & Gauvin-Bialecki, A. (23 April 2023). Cytotoxic Metabolites from Calophyllum tacamahaca Willd.: Isolation and Detection through Feature-Based Molecular Networking. Metabolites, 13 (5), 582. doi:10.3390/metabo13050582
Peer Reviewed verified by ORBi

Le Loar, A., Marcellin-Gros, R., Dufossé, L., Bignon, J., Frederich, M., Ledoux, A., Ferreira Queiroz, E., Wolfender, J.-L., Gauvin-Bialecki, A., & Fouillaud, M. (27 February 2023). Prioritization of Microorganisms Isolated from the Indian Ocean Sponge Scopalina hapalia Based on Metabolomic Diversity and Biological Activity for the Discovery of Natural Products. Microorganisms, 11 (3), 697. doi:10.3390/microorganisms11030697
Peer Reviewed verified by ORBi

Bonnet, O., Beniddir, M. A., Champy, P., Degotte, G., Coelho Cristino Mamede, L. C., Desdemoustier, P., Ledoux, A., Tchinda, A. T., Angenot, L., & Frederich, M. (01 February 2023). Molecular network annotations from 43 Strychnos extracts based on their in vitro antiplasmodial activities in order to detect and target new alkaloids potentially active against malaria [Paper presentation]. 5th CIRM Day, Liège, Belgium.

Kchaou, I., Hamann, C., Massis, S., Etienne, D., Frederich, M., & Ledoux, A. (01 February 2023). A comparative quality control study of Mentha piperita essential oils [Poster presentation]. CIRM-Day, Liège, Belgium.
Peer reviewed

Ledoux, A., Hamann, C., Bonnet, O., Jullien, K., Quetin-Leclercq, J., Tchinda, A., Smadja, J., Gauvin-Bialecki, A., Maquoi, E., & Frederich, M. (25 January 2023). Bioactive Clerodane Diterpenoids from the Leaves of Casearia coriacea Vent. Molecules, 28 (3), 1197. doi:10.3390/molecules28031197
Peer Reviewed verified by ORBi

Bonnet, O., Beniddir, M. A., Champy, P., Kagisha, V., Nyirimigabo, A., Hamann, C., Jgerenaia, G., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (2022). In-depth exploration of Strychnos alkaloids by molecular networking: Discovery of strychnine in new species. Planta Medica.
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Fall, F., Schoumacher, M., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., & Frederich, M. (2022). Recent metabolomic developments for antimalarial drug discovery. Parasitology Research. doi:10.1007/s00436-022-07673-7
Peer Reviewed verified by ORBi

Bonnet, O., Beniddir, M. A., Champy, P., Degotte, G., Coelho Cristino Mamede, L. C., Desdemoustier, P., Ledoux, A., Tchinda, A. T., Angenot, L., & Frederich, M. (26 September 2022). Unveiling antiplasmodial alkaloids from a cumulative collection of Strychnos extracts by multi-informative molecular networks. Frontiers in Molecular Biosciences, 9. doi:10.3389/fmolb.2022.967012
Peer Reviewed verified by ORBi

Leka, K., Ledoux, A., Desdemoustier, P., Garigliany, M.-M., & Frederich, M. (29 August 2022). TRADITIONAL CHINESE MEDICINE: A PATH WORTH EXPLORING IN THE FIGHT AGAINST COVID-19? [Poster presentation]. 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Thessaloniki, Greece.

Hamann, C., Jansen, O., Desdemoustier, P., Ledoux, A., Maquoi, E., & Frederich, M. (28 August 2022). Characterization of the type of interaction between terpenoids and cannabinoids compounds of hemp plant against MDA-MB-231 cancer-cells by isobologram analyses [Poster presentation]. 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Thessalonique, Greece.
Peer reviewed

Bonnet, O., Beniddir, M. A., Champy, P., Degotte, G., Coelho Cristino Mamede, L. C., Desdemoustier, P., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (13 July 2022). Identification of new alkaloids active against malaria by molecular networking based on in vitro antiplasmodial activities of 28 Strychnos species [Paper presentation]. Journées virtuelles de l'AFERP 2022 (Virtual days of AFERP 2022).

Mbombo Mungitshi, P., Frederich, M., Ledoux, A., Mutwale Kapepula, P., Ngombe Kabamba, N., & Tiabou Tchinda, A. (2022). ETUDE PHYTOCHIMIQUE ET EVALUATION DE L'ACTIVITE ANTIPLASMODIALE DE PSEUDOLACHNOSTYLIS MAPROUNEIFOLIA PAX (EUPHORBIACEAE).

Bonnet, O., Beniddir, M. A., Champy, P., Kagisha, V., Nyirimigabo, A., Hamann, C., Jgerenaia, G., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (09 June 2022). Exploration by molecular networking of Strychnos alkaloids reveals the unexpected occurrence of strychnine in seven Strychnos species. Toxicon, 215, 57-68. doi:10.1016/j.toxicon.2022.06.002
Peer Reviewed verified by ORBi

Ledoux, A. (25 May 2022). In vitro activity against SARS-CoV-2 of common herbal medicinal extracts and their bioactive compounds [Paper presentation]. CIRM Seminar, Liège, Belgium.

Leka, K., Hamann, C., Desdemoustier, P., Frederich, M., Garigliany, M.-M., & Ledoux, A. (2022). In vitro antiviral activity against SARS-CoV-2 of common herbal medicinal extracts and their bioactive compounds. Phytotherapy Research. doi:10.1002/ptr.7463
Peer Reviewed verified by ORBi

Fall, F., Coelho Cristino Mamede, L. C., Schioppa, L., Ledoux, A., De Tullio, P., Michels, P., Frederich, M., & Quetin-Leclercq, J. (19 March 2022). Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery. Metabolomics, 18 (4), 20. doi:10.1007/s11306-022-01880-0
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Schoumacher, M., Cirillo, A., Fall, F., Bugli, C., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (02 February 2022). Exploration of untargeted metabolomic extraction methods of in vitro malaria samples by 1H NMR analysis - follow up [Poster presentation]. CIRM Day, Liège, Belgium.

Bonnet, O., Beniddir, M. A., Champy, P., Kagisha, V., Nyirimigabo, A., Hamann, C., Jgerenaia, G., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (02 February 2022). Chemometric study of Strychnos species by molecular networking: example of the occurrence of strychnine [Paper presentation]. 4th CIRM Day, Liège, Belgium.

Ledoux, A., Leka, K., Bonnet, O., Blanquer, A., Tiabou Tchinda, A., Mirowski, P., Figueiredo, P., Desmecht, D., Garigliany, M.-M., & Frederich, M. (10 January 2022). In vitro antiviral activity against SARS-CoV-2 of 28 Strychnos extracts. Phytotherapy Research, 36 (3), 1061-1063. doi:10.1002/ptr.7394
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Schoumacher, M., Cirillo, A., Fall, F., Bugli, C., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (November 2021). Exploration of untargeted metabolomic extraction methods for in vitro malaria samples by 1H NMR analysis [Poster presentation]. 14èmes Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique, Aussois, France.

Ledoux, A. (11 August 2021). Liposomes contre Malaria : vers la fin d’un long combat ? [Paper presentation]. Journée Scientifique Nanotechnology Day, Kinshasa, Congo - Brazzaville.

Ledoux, A., Bériot, D., Coelho Cristino Mamede, L. C., Desdemoustier, P., Detroz, F., Jansen, O., Frederich, M., & Maquoi, E. (2021). Cytotoxicity of Poupartone B, an Alkyl Cyclohexenone Derivative from Poupartia borbonica, against Human Cancer Cell Lines. Planta Medica. doi:10.1055/a-1532-2384
Peer Reviewed verified by ORBi

Tomani, J. C. D., Bonnet, O., Nyirimigabo, A., Deschamps, W., Tchinda, A. T., Jansen, O., Ledoux, A., Mukazayire, M.-J., Vanhamme, L., Frederich, M., Muganga, R., & Souopgui, J. (10 May 2021). In Vitro Antiplasmodial and Cytotoxic Activities of Compounds from the Roots of Eriosema montanum Baker f. (Fabaceae). Molecules, 26 (9), 2795. doi:10.3390/molecules26092795
Peer Reviewed verified by ORBi

Kowa, T., Jansen, O., Ledoux, A., Coelho Cristino Mamede, L. C., Wabo, H., Tchinda Tiabou, A., Genta-Jouve, G., & Frederich, M. (2021). Bioassay-guided isolation of vilasinin–type limonoids and phenyl alkene from the leaves of Trichilia gilgiana and their antiplasmodial activities. Natural Product Research. doi:10.1080/14786419.2021.1920017
Peer Reviewed verified by ORBi

Nea, F., Bitchi, B. M., Genva, M., Ledoux, A., Tchinda Tiabou, A., Frederich, M., Tonzibo, Z. F., & Fauconnier, M.-L. (15 January 2021). Phytochemical investigation and biological activities from Lantana rhodesiensis Moldenke [Poster presentation]. Les Journées Jeunes Chercheurs Condorcet - J2C2.

Nea, F., Bitchi, M. B., Genva, M., Ledoux, A., Tchinda Tiabou, A., Damblon, C., Frederich, M., Tonzibo, Z. F., & Fauconnier, M.-L. (2021). Phytochemical investigation and biological activities of Lantana rhodesiensis. Molecules, 26 (4), 846. doi:10.3390/molecules26040846
Peer Reviewed verified by ORBi

Kagisha, V., Marini Djang'Eing'A, R., Muganga, R., Bonnet, O., Tchinda, A. T., Jansen, O., Tomani, J. C., Ranarivelo, N., Ledoux, A., Nyirimigabo, A., & Frederich, M. (2021). Pentas longiflora Oliv. (Rubiaceae), a plant used in the treatment of Pityriasis Versicolor in Rwanda: Chemical composition and standardization of leaves and roots. Fitoterapia, 153, 104974. doi:10.1016/j.fitote.2021.104974
Peer Reviewed verified by ORBi

Kagisha, V., Frederich, M., Ledoux, A., Jansen, O., NYIRIMIGABO, A., MUGANGA, R., & Marini Djang'Eing'A, R. (10 June 2020). HPLC-UV Method for Standardization of Neorautanenia mitis, an African Plant Used in an Anti-Scabies Ointment. Revista Brasileira de Farmacognosia, 30 (4), 582-587. doi:10.1007/s43450-020-00070-0
Peer reviewed

Ledoux, A., Coelho Cristino Mamede, L. C., Palazzo, C., Furst, T., Jansen, O., De Tullio, P., Kagisha, V., Pendeville-Samain, H., Fillet, M., Piel, G., & Frederich, M. (18 May 2020). Heparin-Coated Liposomes Improve Antiplasmodial Activity and Reduce the Toxicity of Poupartone B. Planta Medica International Open, 7 (e), 73–80. doi:10.1055/a-1158-0569
Peer Reviewed verified by ORBi

Jansen, O., & Ledoux, A. (2020). L'aromathérapie: potentialités et limites [Paper presentation]. Conférence Uliège: saison 2019-2020, module 2: la phytothérapie, Verviers, Belgium.

Ledoux, A., & Jansen, O. (2020). La découverte de médicaments antipaludiques dans les plantes utilisées en médecine traditionnelle [Paper presentation]. Conférence Uliège: saison 2019-2020, module 2: la phytothérapie, Verviers, Belgium.

Tanoh, A. E., Boue, G. B. (Other coll.), Nea, F. (Other coll.), Martin, H. (Other coll.), Genva, M. (Other coll.), Ledoux, A. (Other coll.), Tonzibo, Z. F. (Other coll.), & Fauconnier, M.-L. (Other coll.). (31 January 2020). Seasonal effect on the chemical composition of essential oils hydrodistillated from Zanthoxylum leprieurii Guill. & Perr. and on their biological activities [Paper presentation]. 25th National Symposium for Applied Biological Sciences (NSABS), Gembloux, Belgium.

Tanoh, A. E., Blanchard Boué, G., Nea, F., Genva, M., Wognin, E. L., Ledoux, A., Martin, H., Tonzibo, Z. F., Frederich, M., & Fauconnier, M.-L. (2020). Seasonal effect on the chemical composition, insecticidal properties and other biological activities of Zanthoxylum leprieurii Guill. & Perr. essential oils. Foods, 9 (5), 550. doi:10.3390/foods9050550
Peer Reviewed verified by ORBi

Tomani, J. C. D., Kagisha, V., Tchinda, A. T., Jansen, O., Ledoux, A., Vanhamme, L., Frederich, M., Muganga, R., & Souopgui, J. (2020). The Inhibition of NLRP3 Inflammasome and IL-6 Production by Hibiscus noldeae Baker f. Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials. Molecules, 25 (20), 4693. doi:10.3390/molecules25204693
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Ledoux, A., Jansen, O., & Frederich, M. (2020). Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents. Planta Medica, 86 (9), 585-618. doi:10.1055/a-1148-9000
Peer Reviewed verified by ORBi

Ledoux, A., & Frederich, M. (11 December 2019). Antiplasmodial and antimalarial models for the detection of promising natural compounds [Paper presentation]. Mission de Coopération au Développement, Butare, Rwanda.

Clain, M.-E., Gils, M., Ledoux, A., Desdemoustier, P., Turki, C., Jérusalem, M., Frederich, M., & Castillo Cabello, G. (11 December 2019). Antiplasmodial activity and chemical composition of Belgian mushrooms [Poster presentation]. 2nd CIRM Scientific Day.

Gils, M., Ledoux, A., Davoine, C., Desdemoustier, P., Clain, M.-E., Castillo Cabello, G., Frederich, M., & Fillet, M. (11 December 2019). Affinity capillary electrophoresis as a tool for the discovery of new antimalarial natural compounds [Poster presentation]. 2nd CIRM Scientific Day.

Turki, C., Ledoux, A., Desdemoustier, P., Bonnet, O., & Frederich, M. (11 December 2019). Contribution to the phytochemical study of Casearia coriaceae Vent [Poster presentation]. 2nd CIRM Scientific Day.

Jansen, O., Desdemoustier, P., Ledoux, A., Marotte, A., DJIERRO, K., Hamann, C., & Frederich, M. (August 2019). SCREENING OF 25 EUPHORBIACEAE FOR THEIR IN VITRO ANTIPLASMODIAL PROPERTIES [Poster presentation]. Natural Products in Drug Discovery and Human Health, LISBONNE, Portugal.
Editorial reviewed

Kagisha, V., Frederich, M., Marini Djang'Eing'A, R., MUGANGA, R., Ledoux, A., Jansen, O., & katembezi, A. (17 May 2019). ESTABLISHMENT AND VALIDATION OF CHROMATOGRAPHIC METHODS FOR STANDARDIZATION OF NEORAUTANENIA MITIS, A MEDICINAL PLANT USED IN AN ANTI-SCABIES OINTMENT IN RWANDA [Poster presentation]. 4e' edition du Phytoday, Bruxelles, Belgium.

Ledoux, A., Coelho Cristino Mamede, L. C., Jansen, O., Desdemoustier, P., Palazzo, C., Hamann, C., Piel, G., & Frederich, M. (17 May 2019). Natural compound-containing liposomes: a strategy for targeted activities toward artemisinin-resistant Plasmodium falciparum isolate [Poster presentation]. 4th Phytoday, Belgium.
Peer reviewed

Ledoux, A. (2019). Des liposomes contre la malaria. Le Patient, (33), p. 13.

Ledoux, A. (2019). Étude des potentialités antiplasmodiales de plantes endémiques des Mascareignes: Poupartia borbonica Gmel., une nouvelle source de composés antimalariques prometteurs ? [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/234062

Ielciu, I., Frederich, M., Hanganu, D., Angenot, L., Olah, N.-K., Ledoux, A., Crișan, G., & Păltinean, R. (2019). Flavonoid Analysis and Antioxidant Activities of the Bryonia alba L. Aerial Parts. Antioxidants, 8 (4 108). doi:10.3390/antiox8040108
Peer Reviewed verified by ORBi

Ielciu, I.-I., Mouithys-Mickalad, A., Franck, T., Angenot, L., Ledoux, A., Păltinean, R., Cieckiewicz, E., Etienne, D., Tits, M., Crişan, G., & Frederich, M. (2019). Flavonoid composition, cellular antioxidant activity and (myelo)peroxidase inhibition of a Bryonia alba L. (Cucurbitaceae) leaves extract. Journal of Pharmacy and Pharmacology, 71, 230-239. doi:10.1111/jphp.13025
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Ledoux, A., Desdemoustier, P., Jansen, O., Piel, G., Fillet, M., De Tullio, P., & Frederich, M. (19 December 2018). Quantitative analysis of a natural compound and heparin by HPLC-DAD and 1H NMR for the characterization of a liposomal formulation [Poster presentation]. The first CIRM scientific Day, Liège, Belgium.

Ledoux, A. (01 December 2018). Natural compound-containing liposome as strategy against resistant P.falciparum and cytotoxicity [Paper presentation]. 1st CIRM scientific day.

Degotte, G., Halleux, A., Hans, A., Jansen, O., Ledoux, A., Desdemoustier, P., Pirotte, B., Francotte, P., & Frederich, M. (December 2018). Preparation of ellagic acid derivatives through a total synthesis approach to improve bioavailability [Poster presentation]. 1st CIRM Day, Liège, Belgium.

Coelho Cristino Mamede, L. C., Degotte, G., Ledoux, A., Jansen, O., Desdemoustier, P., & Frederich, M. (November 2018). Antiplasmodial activity and interaction between cannabidiol and artemisinin [Poster presentation]. 30th International Symposium on the Chemistry of Natural Products and the 10th International Conference on Biodiversity, Athens, Greece.

Degotte, G., Francotte, P., Frederich, M., Halleux, A., Hans, A., Jansen, O., Ledoux, A., Desdemoustier, P., & Pirotte, B. (November 2018). Pharmacomodulation of ellagic acid, a promising antiplasmodial agent, to improve its bioavailability [Poster presentation]. 30th International Symposium on the Chemistry of Natural Products and the 10th International Conference on Biodiversity, Athens, Greece.

Beaufay, C., Ledoux, A., Frederich, M., Quetin-Leclercq, J., Zhao, S., Teijaro, C., Andrade, R., & Jansen, O. (July 2018). Antimalarial and antitrypanosomal activity of strychnogucine B, a bisindole alkaloid from Strychnos icaja [Poster presentation]. 3eme symposium international AFERP STOLON.

Ledoux, A., Coelho Cristino Mamede, L. C., Jansen, O., Hae Choi, Y., & Frederich, M. (23 May 2018). NMR Metabolomic analysis as a tool to identify antiplasmodial compounds in Poupartia borbonica extracts [Poster presentation]. 11èmes journées scientifiques du RFMF, Liège, Belgium.

Ledoux, A., Cao, M., Jansen, O., Coelho Cristino Mamede, L. C., Campos, P.-E., Payet, B., Clerc, P., Grondin, I., Girard-Valenciennes, E., Hermann, T., Litaudon, M., Vanderheydt, C., Delang, L., Neyts, J., Leyssen, P., Frederich, M., & Smadja, J. (2018). Antiplasmodial, Anti-chikungunya virus and Antioxidant Activities of 64 endemic Plants from the Mascarene Islands. International Journal of Antimicrobial Agents, 52 (5), 622-628. doi:10.1016/j.ijantimicag.2018.07.017
Peer Reviewed verified by ORBi

Beaufays, C.* , Ledoux, A.* , Jansen, O., bordignon, A., Zhao, S., Teijaro, C., Andrade, R., Quetin-Leclercq, J., & Frederich, M. (2018). In vivo antimalarial and antitrypanosomal activity of strychnogucine B, a bisindole alkaloid from Strychnos icaja. Planta Medica, 84, 881-885. doi:10.1055/a-0644-2723
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Bordignon, A., Frederich, M., Ledoux, A., Campos, P.-É., Clerc, P., Hermann, T., Quetin-Leclercq, J., & Cieckiewicz, E. (2017). In vitro antiplasmodial and cytotoxic activities of sesquiterpene lactones from Vernonia fimbrillifera Less. (Asteraceae). Natural Product Research, 1-4. doi:10.1080/14786419.2017.1350665
Peer Reviewed verified by ORBi

Issac, M., Aknin, M., Gauvin-Bialecki, A., De Voogd, N., Ledoux, A., Frederich, M., Kashman, Y., & Carmeli, S. (16 February 2017). Cyclotheonellazoles A–C, Potent Protease Inhibitors from the Marine Sponge Theonella aff. swinhoei. Journal of Natural Products, 80, 1110-1116. doi:10.1021/acs.jnatprod.7b00028
Peer Reviewed verified by ORBi

Jansen, O., Tchinda, A. T., Loua, J., Esters, V., Cieckiewicz, E., Ledoux, A., Toukam, P. D., Angenot, L., Tits, M., Balde, A. M., & Frederich, M. (2017). Antiplasmodial activity of Mezoneuron benthamianum leaves and identification of its active constituents. Journal of Ethnopharmacology, 203 (March), 20-26. doi:10.1016/j.jep.2017.03.021
Peer Reviewed verified by ORBi

Ledoux, A., St-Gelais, A., Cieckiewicz, E., Jansen, O., Bordignon, A., Illien, B., Di Giovanni, N., Marvilliers, A., Hoareau, F., Pendeville-Samain, H., Leclercq, J., & Frederich, M. (2017). Antimalarial Activities of Alkyl Cyclohexenone Derivatives Isolated from the Leaves of Poupartia borbonica. Journal of Natural Products, 80 (6), 1750-1757. doi:10.1021/acs.jnatprod.6b01019
Peer Reviewed verified by ORBi

Ebralidze, L., Mskhiladze, L., Ledoux, A., Frederich, M., Bellahcene, A., Bero, J., Quetin-Leclercq, J., & Bakuridze, A. (2017). ANTICANCER, ANTIPLASMODIAL AND ANTITRYPANOSOMAL ACTIVITIES OF CRUDE EXTRACTS OF PLATANUS ORIENTALIS. World Journal of Pharmaceutical Research, 6 (3), 170-175. doi:10.20959/wjpr20173-7985
Peer reviewed

Frederich, M., & Ledoux, A. (16 November 2016). Potential Antimalarials from Tropical Plants and Natural Products [Paper presentation]. CIRM seminar.

Tchinda Tiabou, A., Loua, J., Esters, V., Cieckiewicz, E., Ledoux, A., Angenot, L., Tits, M., Baldé, A. M., Frederich, M., & Jansen, O. (July 2016). Study of Mezoneuron benthamianum, a plant traditionally used against malaria in Guinea [Poster presentation]. 9th Joint Natural Products Conference 2016 Copenhagen, Copenhagen, Denmark.

Mskhiladze, L., Chincharadze, D., St-Gelais, A., Mshvildadze, V., Pichette, A., Ledoux, A., Tits, M., & Frederich, M. (July 2016). Isolation and Identification of Steroid and Flavonoid Glycosides from the Flowers of Allium gramineum. International Journal of Pharmaceutical Sciences and Drug Research, 8 (4), 240-243.
Peer reviewed

Ledoux, A., Jansen, O., St-Gelais, A., Cieckiewicz, E., Ielciu, I.-I., Bialecki, A., Bero, J., & Frederich, M. (July 2016). New antimalarial compounds isolated from Poupartia borbonica, a Mascarene Islands endemic plant. Planta Medica, 82 (S01), 1-S381.
Peer Reviewed verified by ORBi

Marquise, N., Chevallier, F., Nassar, E., Frederich, M., Ledoux, A., Halauko, Y. S., Ivashkevich, O. A., Matulis, V. E., Roisnel, T., Dorcet, V., & Mongin, F. (February 2016). Substituted azafluorenones: access from dihalogeno diaryl ketones by palladium-catalyzed auto-tandem processes and evaluation of their antibacterial, antifungal, antimalarial and antiproliferative activities. Tetrahedron, 72 (6), 825-836. doi:10.1016/j.tet.2015.12.050
Peer Reviewed verified by ORBi

Bordignon, A., Cieckiewicz, E., Jansen, O., Ledoux, A., Campos, P.-E., Smaja, J., Quetin-Leclercq, J., & Frederich, M. (14 October 2015). Isolation, caracterisation and antiplasmodial activity evaluation of compounds from Reunion Island endemic plants [Poster presentation]. 2nd International conference on natural products utilization : from plants to pharmacy shelf (ICNPU), Plovdiv, Bulgaria.

Bordignon, A., Cieckiewicz, E., Jansen, O., Ledoux, A., Campos, P.-E., Smaja, J., Quetin-Leclercq, & Frederich, M. (16 July 2015). Isolation and identification of potential antimalarial compounds from endemic plants of Reunion Island [Poster presentation]. 2ème symposium international AFERP-STOLON -Biodiversité et substances naturelles-, Lyon, France.

Ledoux, A., Martin, B., De Tullio, P., Tits, M., Wauters, J.-N., Choi, Y. H., Bodson, M., & Frederich, M. (16 July 2015). Metabolomics analysis of Galium odoratum (L.) Scop.: impact of the plant population origin and growth conditions [Poster presentation]. 2ème Symposium international AFERP – STOLON, Lyon, France.

Ledoux, A., Bordignon, A., Campos, P.-É., Grondin, I., Smadja, J., & Frederich, M. (July 2015). Screening of medicinal plants from Reunion Island for antimalarial activity [Poster presentation]. Joint meeting of the GP-TCM Research Association, the TCM Chemistry Specialty Committee and the TCM Pharmaceutical Analysis Specialty Committee of the World Federation of Chinese Medicine Societies, Mons, Belgium.

Ledoux, A., Jansen, O., Campos, P.-É., Grondin, I., Smadja, J., & Frederich, M. (May 2015). Identification of antiplasmodial compounds isolated from endemic plants of Reunion Island [Paper presentation]. 18th Forum of Pharmaceutical Sciences.

Ledoux, A., Mareatefau, H., Jansen, O., Etienne, D., quetin-Leclercq, J., Clerc, P., Smadja, J., & Frederich, M. (April 2015). Phytochemical Profile and Biological Activity Evaluation of Zanthoxylum heterophyllum Leaves against Malaria. Planta Medica Letters, 2, 10-e11.
Peer Reviewed verified by ORBi

Gallé, J.-B., Groeber, S., Ledoux, A., & Nicolas, J.-P. (2014). Quelques plantes employées dans le Sud-Ouest de Madagascar. Éditions Jardins du Monde.

Ledoux, A., Groeber, S., Gallé, J.-B., Jansen, O., Frederich, M., & Nicolas, J.-P. (19 December 2013). Approche ethnobotanique des savoirs traditionnels et de l’utilisation des plantes médicinales appliqués à la période périnatale dans le Sud-Ouest de Madagascar [Poster presentation]. Territoires périurbains dans les pays du Sud, Colloque Pacodel.

Groeber, S., Gallé, J.-B., Nicolas, J.-P., & Ledoux, A. (November 2012). Savoirs traditionnels et plantes médicinales, mise en oeuvre de la démarche de l'ethnopharmacologie appliquée dans le Sud-Ouest de Madagascar [Poster presentation]. 7ème CIPAM - Colloque International sur les Plantes Aromatiques et Médicinales des régions d'outre-mer.

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