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Ceccato Attilio

Département de pharmacie > Chimie analytique

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Main Referenced Co-authors
Hubert, Philippe  (117)
Crommen, Jacques  (84)
Chiap, Patrice  (49)
Boulanger, Bruno  (27)
Toussaint, B. (24)
Main Referenced Keywords
Design space (4); validation (4); Design of experiments (3); design space (3); Spectroscopie proche infrarouge (3);
Main Referenced Unit & Research Centers
C.I.R.M. (5)
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (4)
CIRM - Centre interfacultaire de recherche du médicament (1)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (117)
Chemistry (12)
Physical, chemical, mathematical & earth Sciences: Multidisciplinary, general & others (5)
Biochemistry, biophysics & molecular biology (2)

Publications (total 121)

The most downloaded
474 downloads
Debrus, B., Lebrun, P., Boulanger, B., Rozet, E., Caliaro, G., Ceccato, A., & Hubert, P. (2010). Development of robust analytical methods using design space methodology [Poster presentation]. Chimiométrie 2010, Paris, France. https://hdl.handle.net/2268/75889

The most cited

230 citations (Scopus®)

Rozet, E., Ceccato, A., Hubert, C., Ziemons, E., Oprean, R., Rudaz, S., Boulanger, B., & Hubert, P. (2007). Analysis of recent pharmaceutical regulatory documents on analytical method validation. Journal of Chromatography. A, 1158 (1-2), 111-25. doi:10.1016/j.chroma.2007.03.111 https://hdl.handle.net/2268/3646

Nistor, I., Lebrun, P., Ceccato, A., Lecomte, F., Slama, I., Oprean, R., Badarau, E., Dufour, F., Dossou, K. S. S., Fillet, M., Liégeois, J.-F., Hubert, P., & Rozet, E. (2013). Implementation of a Design Space Approach for Enantiomeric Separations in Polar Organic Solvent Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 74, 273-283. doi:10.1016/j.jpba.2012.10.015
Peer Reviewed verified by ORBi

Ziemons, E., Ceccato, A., & Hubert, P. (2012). Content uniformity determination in silicone-based drug reservoirs by near infrared spectroscopy.

Lecomte, F., Hubert, C., Demarche, S., De Bleye, C., Dispas, A., Jost, M., Frankenne, F., Ceccato, A., Rozet, E., & Hubert, P. (05 January 2012). Comparison of the quantitative performances and measurement uncertainty estimates obtained during method validation versus routine applications of a novel hydrophilic interaction chromatography method for the determination of cidofovir in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 57, 153-165. doi:10.1016/j.jpba.2011.08.040
Peer Reviewed verified by ORBi

Mantanus, J., Rozet, E., Van Butsele, K., De Bleye, C., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (October 2011). Silicone-based drug reservoirs manufacturing process - Critical quality attributes evaluation using NIR and Raman spectroscopy [Poster presentation]. AAPS Annual Meeting and Exposition, Washington, United States.

De Bleye, C., Mantanus, J., Rozet, E., Van Butsele, K., Marini Djang'Eing'A, R., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (September 2011). BUILDING THE QUALITY INTO THE POLYMERIC SOLID DOSAGE FORM MANUFACTURING LINE - CRITICAL QUALITY ATTRIBUTES EVALUATION WITH NIR AND RAMAN PAT TOOLS [Poster presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Hubert, C., Streel, B., Sibenaler, R., Widart, J., Ceccato, A., & Hubert, P. (19 June 2011). High Throughput determination of Levonorgestrel in human plasma using a Sensitive LC-MS/MS method [Poster presentation]. 36th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Budapest, Hungary.

Nistor, I., Lebrun, P., Ceccato, A., Lecomte, F., Slama, I., Rozet, E., Oprean, R., Badarau, E., Dufour, F., Liégeois, J.-F., & Hubert, P. (2011). Implementation of a design space approach for enatiomeric separations in polar organic solvent chromatography [Poster presentation]. 36th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, Budapest, Hungary.

Mantanus, J., Rozet, E., Van Butsele, K., De Bleye, C., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (2011). Near infrared and Raman spectroscopy as Process Analytical Technology tools for the manufacturing of silicone-based drug reservoirs. Analytica Chimica Acta, 699, 96-106. doi:10.1016/j.aca.2011.05.006
Peer Reviewed verified by ORBi

Debrus, B., Lebrun, P., Mbinze Kindenge, J., Lecomte, F., Ceccato, A., Caliaro, G., Mavar Tayey Mbay, J., Boulanger, B., Marini Djang'Eing'A, R., Rozet, E., & Hubert, P. (2011). Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments, independent component analysis and design space. Journal of Chromatography. A, 1218, 5205-5215. doi:10.1016/j.chroma.2011.05.102
Peer Reviewed verified by ORBi

Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Rozet, E., Nistor, I., Oprean, R., Rupérez, F. J., Barbas, C., Boulanger, B., & Hubert, P. (2011). Application of new methodologies based on design of experiments, independent component analysis and design space for robust optimization in liquid chromatography. Analytica Chimica Acta, 691, 33-42. doi:10.1016/j.aca.2011.02.035
Peer Reviewed verified by ORBi

Lecomte, F., Jasselette, C., Hubert, C., Demarche, S., De Bleye, C., Ceccato, A., Rozet, E., & Hubert, P. (September 2010). Validation of a HILIC method for the determination of cidofovir in plasma [Poster presentation]. Drug Analysis 2010 - International Symposium on Drug Analysis, Antwerp, Belgium.

Debrus, B., Lebrun, P., Boulanger, B., Rozet, E., Caliaro, G., Ceccato, A., & Hubert, P. (September 2010). Implementation of design space concept for the development of robust analytical methods [Poster presentation]. Drug Analysis 2010, Anvers (Antwerp), Belgium.

Mantanus, J., Ziemons, E., Evrard, B., Van Butsele, K., Ceccato, A., & Hubert, P. (05 May 2010). NIR Real-time monitoring of a silicone-based drug reservoir crosslinking process [Poster presentation]. 4th Pan European Pat Science conference, Kuopio, Finland.

Ziemons, E., Ceccato, A., & Hubert, P. (2010). Utilisation de la spectroscopie proche infrarouge dans la cadre de la fabrication d'un dispositif intra-utérin. (3eme semestre & Final).

Rozet, E., Bouabidi, A., Fillet, M., Ziemons, E., Chapuzet, E., Mertens, B., Klinkenberg, R., Ceccato, A., Talbi, M., Streel, B., Bouklouze, A., Boulanger, B., & Hubert, P. (2010). Critical analysis of several analytical method validation strategies in the framework of the fit for purpose concept. Journal of Chromatography. A, 1217, 3180-3192. doi:10.1016/j.chroma.2009.08.051
Peer Reviewed verified by ORBi

Debrus, B., Lebrun, P., Boulanger, B., Rozet, E., Caliaro, G., Ceccato, A., & Hubert, P. (2010). Development of robust analytical methods using design space methodology [Poster presentation]. Chimiométrie 2010, Paris, France.

Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Govaerts, B., Olsen, B. A., Rozet, E., Boulanger, B., & Hubert, P. (30 June 2009). A new statistical method for the automated detection of peaks in UV-DAD chromatograms of a sample mixture. Talanta, 79, 77-85. doi:10.1016/j.talanta.2009.03.009
Peer Reviewed verified by ORBi

Nistor, I., Debrus, B., Lebrun, P., Rozet, E., Ceccato, A., Caliaro, G., Oprean, R., Boulanger, B., & Hubert, P. (27 April 2009). Nouvelle méthodologie pour le développement automatisé de méthodes analytiques en chromatographie liquide pour l'analyse de mélanges de composés inconnus [Paper presentation]. Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium.

Ziemons, E., Ceccato, A., & Hubert, P. (2009). Utilisation de la spectroscopie proche infrarouge dans la cadre de la fabrication d'un dispositif intra-utérin. (2ème semestre).

Ziemons, E., Ceccato, A., & Hubert, P. (2008). Utilisation de la spectroscopie proche infrarouge dans la cadre de la fabrication d'un dispositif intra-utérin. (1er semestre).

Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Rozet, E., Rupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (July 2008). Chromatographic separation of a pharmaceutical formulation using Design of Experiment and Design Space [Poster presentation]. 11th conference on Chemometrics in Analytical Chemistry (CAC'2008), Montpellier, France.

Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Jupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (June 2008). Usefulness of design space for the optimization of chromatographic separations [Paper presentation]. 19th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2008), Gdansk, Poland.

Lebrun, P., Govaerts, B., Debrus, B., Ceccato, A., Caliaro, G., Hubert, P., & Boulanger, B. (2008). Development of a new predictive modelling technique to find with confidence equivalence zone and design space of chromatographic analytical methods. Chemometrics and Intelligent Laboratory Systems, 91, 4-16. doi:10.1016/j.chemolab.2007.05.010
Peer Reviewed verified by ORBi

Rozet, E., Hubert, C., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (27 July 2007). Using tolerance intervals in pre-study validation of analytical methods to predict in-study results - The fit-for-future-purpose concept. Journal of Chromatography. A, 1158 (1-2), 126-137. doi:10.1016/j.chroma.2007.03.102
Peer Reviewed verified by ORBi

Lebrun, P., Debrus, B., Boulanger, B., Caliaro, G., Ceccato, A., & Hubert, P. (June 2007). Numerical separation in HPLC-UV-DAD with Independent Component Analysis (ICA) using high order statistics for the automated identification of peaks [Poster presentation]. HPLC 2007, Gent, Belgium.

Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Séparation numérique et quantification automatique de pics en CLHP-UV grâce à l’utilisation de l’analyse en composantes indépendantes (ICA) [Paper presentation]. SEP 2007, Grenoble, France.

Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Evaluation d'une nouvelle méthode pour le développement entièrement automatisé de méthodes analytiques en chromatographie liquide [Poster presentation]. SEP 2007, Grenoble, France.

Hubert, C., Rozet, E., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (March 2007). Validation versus routine : Evaluation de l'aspect prédictif de l'intervalle de tolérance [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Grenoble, France.

Rozet, E., Dewe, W., Govaerts, B., Boulanger, B., Ceccato, A., Chiap, P., Crommen, J., & Hubert, P. (2007). Evaluation of Analytical Method Transfer on a Risk Based Methodology using Total Error [Paper presentation]. HPLC.

Rozet, E., Ceccato, A., Hubert, C., Ziemons, E., Oprean, R., Rudaz, S., Boulanger, B., & Hubert, P. (2007). Analysis of recent pharmaceutical regulatory documents on analytical method validation. Journal of Chromatography. A, 1158 (1-2), 111-25. doi:10.1016/j.chroma.2007.03.111
Peer Reviewed verified by ORBi

Boulanger, B., Dewé, W., Ceccato, A., Debrus, B., Lebrun, P., & Hubert, P. (December 2006). Utilisation de l’Analyse en Composantes Indépendantes (ICA) pour la séparation numérique des pics et la quantification automatique en CLHP-UV [Paper presentation]. Chimiométrie 2006, Paris, France.

Rozet, E., Mertens, B., Dewé, W., Ceccato, A., Govaerts, B., Boulanger, B., Chiap, P., Streel, B., Crommen, J., & Hubert, P. (11 September 2006). The transfer of a LC-UV method for the determination of fenofibrate and fenofibric acid in Lidoses: Use of total error as decision criterion. Journal of Pharmaceutical and Biomedical Analysis, 42 (1), 64-70. doi:10.1016/j.jpba.2005.12.037
Peer Reviewed verified by ORBi

Marini Djang'Eing'A, R., Groom, C., Doucet, F. R., Hawari, J., Bitar, Y., Holzgrabe, U., Gotti, R., Schappler, J., Rudaz, S., Veuthey, J.-L., Mol, R., Somsen, G. W., de Jong, G. J., Ha, P. T. T., Zhang, J., Van Schepdael, A., Hoogmartens, J., Brione, W., Ceccato, A., ... Hubert, P. (2006). Interlaboratory study of a NACE method for the determination of R-timolol content in S-timolol maleate: assessment of uncertainty. Electrophoresis, 27 (12), 2386-99. doi:10.1002/elps.200500832
Peer Reviewed verified by ORBi

Rozet, E., Dewe, W., Govaerts, B., Boulanger, B., Ceccato, A., Chiap, P., & Crommen, J. (2006). TOWARDS A RISK BASED METHODOLOGY TO ASSESS THE ACCEPTABILITY OF AN ANALYTICAL METHOD TRANSFER: COMPARISON OF DIFFERENT APPROACHES [Poster presentation]. Drug Analysis.

Streel, B., Ceccato, A., Klinkenberg, R., & Hubert, P. (25 January 2005). Validation of a liquid chromatographic-tandem mass spectrometric method for the determination of loperamide in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 814 (2), 263-273. doi:10.1016/j.jchromb.2004.10.050
Peer Reviewed verified by ORBi

Marini Djang'Eing'A, R., Matthijs, N., Vanderheyden, Y., Smeyers-Verbeke, J., Dehouck, P., Hoogmartens, J., Silvestre, P., Ceccato, A., Goedert, P., Saevels, J., Herbots, C., Caliaro, G., Herraez-Hernandez, R., Verdu-Andres, J., Campins-falco, P., de Wauw, W. V., De Beer, J., Boulanger, B., Chiap, P., ... Hubert, P. (2005). Collaborative study of an liquid chromatographic method for the determination of R-timolol and other related substances in S-timolol maleate. Analytica Chimica Acta, 546 (2), 182-192. doi:10.1016/j.aca.2005.05.026
Peer Reviewed verified by ORBi

Christiaens, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (12 November 2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-110. doi:10.1016/j.chroma.2004.06.107
Peer Reviewed verified by ORBi

Christians, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-10.
Peer Reviewed verified by ORBi

Christiaens, G., Chiap, P., Fillet, M., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). New fully automated method for the LC-MS/MS determination of cyproterone acetate in human plasma using restricted access material for sample clean-up [Poster presentation]. 8th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-8), Bruges, Belgium.

Ceccato, A., Klinkenberg, R., Hubert, P., & Streel, B. (08 August 2003). Sensitive determination of buprenorphine and its N-dealkylated metabolite norbuprenorphine in human plasma by liquid chromatography coupled to tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 32 (4-5), 619-631. doi:10.1016/S0731-7085(03)00169-9
Peer Reviewed verified by ORBi

Chiap, P., Ceccato, A., Gora, R., Hubert, P., Geczy, J., & Crommen, J. (15 January 2002). Automated determination of pirlindole enantiomers in plasma by on-line coupling of a pre-column packed with restricted access material to a chiral liquid chromatographic column. Journal of Pharmaceutical and Biomedical Analysis, 27 (3-4), 447-455. doi:10.1016/S0731-7085(01)00647-1
Peer Reviewed verified by ORBi

Chiap, P., Ceccato, A., Miralles Buraglia, B., Boulanger, B., Hubert, P., & Crommen, J. (March 2001). Development and Validation of an Automated Method for the Liquid Chromatographic Determination of Sotalol in Plasma Using Dialysis and Trace Enrichment on a Cation-Exchange Pre-Column as on-Line Sample Preparation. Journal of Pharmaceutical and Biomedical Analysis, 24 (5-6), 801-14. doi:10.1016/S0731-7085(00)00547-1
Peer Reviewed verified by ORBi

Toussaint, B., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (27 October 2000). Determination of the Enantiomers of 3-Tert.-Butylamino-1,2-Propanediol by High-Performance Liquid Chromatography Using Mass Spectrometric Detection. Journal of Chromatography. A, 896 (1-2), 201-7. doi:10.1016/S0021-9673(00)00558-6
Peer Reviewed verified by ORBi

Toussaint, B., Pitti, C., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (27 October 2000). Quantitative Analysis of N-Acetylcysteine and Its Pharmacopeial Impurities in a Pharmaceutical Formulation by Liquid Chromatography-Uv Detection-Mass Spectrometry. Journal of Chromatography. A, 896 (1-2), 191-9. doi:10.1016/S0021-9673(00)00741-X
Peer Reviewed verified by ORBi

Chiap, P., Buraglia, B. M., Ceccato, A., Hubert, P., & Crommen, J. (10 February 2000). Automated Liquid Chromatographic Determination of Atenolol in Plasma Using Dialysis and Trace Enrichment on a Cation-Exchange Precolumn for Sample Handling. Journal of Chromatography. B, Biomedical Sciences and Applications, 739 (1), 205-17. doi:10.1016/S0378-4347(99)00518-6
Peer Reviewed verified by ORBi

Toussaint, B., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (2000). Determination of N-acetylcysteine and its metabolites in plasma by LC-MS-MS [Poster presentation]. 6th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-6), Brugge, Belgium.

Toussaint, B., Pitti, C., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (2000). Quantitative analysis of N-acetylcysteine and its pharmacopeial impurities in a pharmaceutical formulation by LC-UV-MS [Poster presentation]. 6th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-6), Brugge, Belgium.

Toussaint, B., Streel, B., Ceccato, A., Hubert, P., & Crommen, J. (2000). Determination of 3-tert.butylamino-1,2-propanediol enantiomers by LC-MS-MS [Poster presentation]. 6th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-6), Brugge, Belgium.

Hubert, P., Ceccato, A., Chiap, P., Toussaint, B., & Crommen, J. (1999). Préparation des échantillons d'origine biologique préalable à leur analyse chromatographique. STP Pharma Pratiques, 9 (2), 160-180.
Peer reviewed

Crommen, J., Chiap, P., Ceccato, A., & Hubert, P. (1999). Fully automated methods for the LC determination of drug enantiomers in plasma using precolumns with Restricted Access Material (RAM) for sample pretreatement [Paper presentation]. Internationales LiChrospher ADS Anwender Treffen, Munich, Germany.

Ceccato, A., Toussaint, B., Chiap, P., Hubert, P., & Crommen, J. (1999). Automated Sample Preparation Techniques for the Determination of Drug Enantiomers in Biological Fluids Using Liquid Chromatography with Chiral Stationary Phases. Enantiomer, 4 (3-4), 305-15.
Peer Reviewed verified by ORBi

Crommen, J., Chiap, P., Toussaint, B., Ceccato, A., & Hubert, P. (1999). Développement et validation de méthodes entièrement automatisées pour le dosage de médicaments et de leurs métabolites dans les fluides biologiques [Paper presentation]. SEP’99 Techniques séparatives et couplages, Lyon, France.

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Felikidis, A., Geczy, J., & Crommen, J. (December 1998). Enantiomeric Separation of Pirlindole by Liquid Chromatography Using Different Types of Chiral Stationary Phases. Journal of Pharmaceutical and Biomedical Analysis, 18 (4-5), 605-14. doi:10.1016/S0731-7085(98)00213-1
Peer Reviewed verified by ORBi

Ceccato, A., Boulanger, B., Chiap, P., Hubert, P., & Crommen, J. (11 September 1998). Simultaneous Determination of Methylphenobarbital Enantiomers and Phenobarbital in Human Plasma by on-Line Coupling of an Achiral Precolumn to a Chiral Liquid Chromatographic Column. Journal of Chromatography. A, 819 (1-2), 143-53. doi:10.1016/S0021-9673(98)00547-0
Peer Reviewed verified by ORBi

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Stachow, M., Geczy, J., & Crommen, J. (01 September 1998). Simultaneous Determination of Pirlindole Enantiomers and Dehydropirlindole by Chiral Liquid Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 17 (6-7), 1071-9. doi:10.1016/S0731-7085(98)00073-9
Peer Reviewed verified by ORBi

De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (September 1998). Effective resolution of racemic pirlindole at the preparative scale: derivatization method and absolute configuration [Poster presentation]. XVth EFMC International Symposium on Medicinal Chemistry.

De Tullio, P., Ceccato, A., Liégeois, J.-F., Pirotte, B., Felekidis, A., Stachow, M., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (September 1998). Preparative resolution of racemic pirlindole: chromatographic methods and determination of the absolute configuration [Poster presentation]. Fourth European Congress of Pharmaceutical Sciences, Milan, Italy.

Toussaint, B., Hubert, P., Ceccato, A., Hurlet, V., Rigo, J. M., COUCKE, P., Moonen, G., & Crommen, J. (1998). Vizualization and structural analysis of a neurotoxic astroglia-released factor by liquid chromatography using fluorescence and mass spectrometric detection [Poster presentation]. Bioforum, Liège, Belgium.

De Tullio, P., Felikidis, A., Liégeois, J.-F., Pirotte, B., Stachow, M., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Résolution préparative du pirlindol, journées franco-belges de pharmacochimie. Journal de Pharmacie de Belgique, 53, 55.
Peer Reviewed verified by ORBi

Pirotte, B., De Tullio, P., Stachow, M., Felikidis, A., Liégeois, J.-F., Ceccato, A., Hubert, P., Crommen, J., Geczy, J., & Delarge, J. (1998). Tentatives de synthèse énantiosélective des isomères R et S du pirlindol. Journal de Pharmacie de Belgique, 53, 60.
Peer Reviewed verified by ORBi

Crommen, J., Chiap, P., Toussaint, B., Ceccato, A., & Hubert, P. (1998). Sample preparation strategies for the fully automated determination of drugs and metabolites in biologicals fluids [Paper presentation]. XIV Convegno nazionale, divisione di chimica farmaceutica, Società Chimica Italiana, Salsomaggiore Terme -–Parma, Italy.

Crommen, J., Ceccato, A., Fillet, M., Chiap, P., Toussaint, B., & Hubert, P. (1998). Method development and validation for the individual quantitation of drug en-antiomers using liquid chromatography or capillary electrophoresis [Paper presentation]. 3rd course on chiral chemistry, Project Tempus S-JEP-09101-95 « New Curriculum in Chiral Chemistry ».

Toussaint, B., Ceccato, A., Hubert, P., & Crommen, J. (1998). Quantitative analysis of l-lysine n-acetylcysteinate and related compounds by LC-MS. Journal de Pharmacie de Belgique, 53, 260.
Peer Reviewed verified by ORBi

Gora, R., Ceccato, A., Toussaint, B., Hubert, P., & Crommen, J. (1998). Automated liquid chromatographic analysis of pirlindole enantiomers in plasma using a precolumn with restricted access material in a column switching system [Paper presentation]. 3rd course on chiral chemistry, Project Tempus S-JEP-09101-95 « New Curriculum in Chiral Chemistry », Bratislava, Slovakia.

Chiap, P., Boulanger, B., Ceccato, A., Hubert, P., & Crommen, J. (1998). On-line coupling of dialysis to liquid chromatography for the automated determination of some local anaesthetics in human plasma. Journal de Pharmacie de Belgique, 53, 172.
Peer Reviewed verified by ORBi

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Stachow, M., Geczy, J., & Crommen, J. (1998). Determination of the enantiomeric purity of pirlindole by liquid chromatography using a cellulose based chiral stationary phase. Journal de Pharmacie de Belgique, 53, 169.
Peer Reviewed verified by ORBi

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Felikidis, A., Geczy, J., & Crommen, J. (1998). Liquid chromatographic separation of pirlindole enantiomers using different types of chiral stationary phases. Journal de Pharmacie de Belgique, 53, 168.
Peer Reviewed verified by ORBi

Streel, B., Ceccato, A., Sibenaler, R., Zimmer, C., & Hubert, P. (1998). Simultaneous determination of nifedipine and its metabolite in human plasma by LC/MS/MS using APCI interface [Poster presentation]. 5th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers, Brugge, Belgium.

Toussaint, B., Ceccato, A., Hubert, P., & Crommen, J. (1998). Determination of l-lysine N-acetylcysteinate, its mono- and dimeric related compounds by LC-MS-MS [Poster presentation]. 5th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers, Brugge, Belgium.

Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (26 September 1997). Automated Determination of Tramadol Enantiomers in Human Plasma Using Solid-Phase Extraction in Combination with Chiral Liquid Chromatography. Journal of Chromatography. B, Biomedical Sciences and Applications, 698 (1-2), 161-70. doi:10.1016/S0378-4347(97)00267-3
Peer Reviewed verified by ORBi

Evrard, B., Piel, G., Ceccato, A., & Delattre, L. (July 1997). Effects of cyclodextrins on the solubility characteristics of albendazole [Poster presentation]. Pharmaceutical appplication of Cyclodextrins Conference, Lawrence, Kansas, United States.

Ceccato, A., Toussaint, B., Chiap, P., Hubert, P., & Crommen, J. (June 1997). Enantioselective Determination of Oxprenolol in Human Plasma Using Dialysis Coupled on-Line to Reversed-Phase Chiral Liquid Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 15 (9-10), 1365-74. doi:10.1016/S0731-7085(96)01965-6
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Evrard, B., Ceccato, A., Gaspard, O., Delattre, L., & Delporte, J.-P. (01 May 1997). Stability of Ondansetron Hydrochloride and Dexamethasone Sodium Phosphate in 0.9% Sodium Chloride Injection and in 5% Dextrose Injection. American Journal of Health-system Pharmacy, 54 (9), 1065-8. doi:10.1093/ajhp/54.9.1065
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Boulanger, B., Ceccato, A., Chiap, P., & Hubert, P. (1997). Selecting Derringer’s desirability functions that guarantee Pareto optimality : an application to the optimization of a liquid chromatography separation [Poster presentation]. HPLC 97, Birmingham, United Kingdom.

Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1997). Coupled-column LC analysis of mephobarbital enantiomers in plasma using restricted access packing material in the precolumn [Paper presentation]. VIth Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Crommen, J., Ceccato, A., Toussaint, B., Chiap, P., & Hubert, P. (1997). Fully automated systems for the liquid chromatographic determination of drug enantiomers in biological fluids [Paper presentation]. VIIth meeting on recent developments in pharmaceutical analysis.

Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1997). Automated determination of tramadol enantiomers in plasma using solid-phase extraction and chiral liquid chromatography [Poster presentation]. VIIIth International Symposium on Pharmaceutical and Biomedical Analysis, Orlando, United States.

Toussaint, B., Ceccato, A., Maes, P., Hubert, P., & Crommen, J. (1997). Determination of N-acetylcysteine and its potential degradation products by LC/APCI+/MS/MS [Paper presentation]. VIth Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Fillet, M., Bechet, I., Ceccato, A., Hubert, P., & Crommen, J. (1997). Enantiomeric separation of basic drugs by CZE using charged and uncharged cyclodextrins as chiral selectors [Poster presentation]. VIIth International Symposium on High Performance Capillary Electrophoresis, Wurzburg, Germany.

Toussaint, B., Ceccato, A., Hubert, P., & Crommen, J. (1997). Determination of N-acetylcysteine and its potential degradation products by LC/MS/MS [Poster presentation]. HPLC 97, Birmingham, United Kingdom.

Chiap, P., Hubert, P., Ceccato, A., & Crommen, J. (1997). Automated LC determination of molsidomine and two of its metabolites in plasma using solid phase extraction as sample pretreatment [Poster presentation]. HPLC’ 97, Birmingham, United Kingdom.

Ceccato, A., Boulanger, B., Chiap, P., Hubert, P., & Crommen, J. (1997). LC determination of mephobarbital enantiomers and phenobarbital in plasma using a precolumn with restricted access sorbent for sample clean-up [Poster presentation]. HPLC’ 97, Birmingham, United Kingdom.

Ceccato, A., Hubert, P., De Tullio, P., Liégeois, J.-F., Pirotte, B., Stachow, M., Delarge, J., Geczy, J., & Crommen, J. (1997). Enantiomeric separation of pirlindole enantiomers and dehydroprilindole by chrial liquid chromatography [Poster presentation]. VIIth meeting on recent developments in pharmaceutical analysis.

Crommen, J., Fillet, M., Ceccato, A., & Hubert, P. (1997). Enantiomeric resolution of drugs by capillary electrophoresis [Paper presentation]. 57th FIP World Congress 1997, Vancouver, Canada.

Chiap, P., Miralles, B., Ceccato, A., Hubert, P., & Crommen, J. (1997). Automated liquid chromatographic determination of atenolol in plasma using dialysis and trace enrichment on a cation exchange precolumn for sample pre-treatement [Poster presentation]. VIIth meeting on recent developments in pharmaceutical analysis.

Chiap, P., Ceccato, A., Miralles, B., Boulanger, B., Hubert, P., & Crommen, J. (1997). On-line combination of dialysis with trace enrichment on a cation-exchange precolumn for the automated LC determination of sotalol in plasma [Poster presentation]. HPLC 97, Birmingham, United Kingdom.

Hubert, P., Ceccato, A., Hurlet, V., Rigo, J.-M., Coucke, P., Moonen, G., & Crommen, J. (1997). Automated determination of tramadol enantiomers in plasma using solid-phase extraction and chiral liquid chromatography [Poster presentation]. Second meeting of the Belgian Society of Neuroscience, Brussels, Belgium.

Ceccato, A., Chiap, P., Hubert, P., Toussaint, B., & Crommen, J. (25 October 1996). Automated Determination of Verapamil and Norverapamil in Human Plasma with on-Line Coupling of Dialysis to High-Performance Liquid Chromatography and Fluorometric Detection. Journal of Chromatography. A, 750 (1-2), 351-60. doi:10.1016/0021-9673(96)00471-2
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Evrard, B., Ceccato, A., Colson, A., Léonard, F., Gaspard, O., Delporte, J.-P., & Delattre, L. (1996). Stability of ondansetron hydrochloride and dexamethazone sodium phosphate admixtures in injectable solutions [Paper presentation]. Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Ceccato, A., Hubert, P., Chiap, P., Toussaint, B., & Crommen, J. (1996). On-line dialysis coupled to liquid chromatography for the automated determination of verapamil and its demethylated metabolite in plasma [Paper presentation]. 4th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyses, Bruges, Belgium.

Ceccato, A., Toussaint, B., Chiap, P., Hubert, P., & Crommen, J. (1996). LC determination of oxprenolol enantiomers in human plasma using dialysis as on-line sample preparation technique. Journal de Pharmacie de Belgique, 51, 106.
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Ceccato, A., Hubert, P., Chiap, P., Toussaint, B., & Crommen, J. (1996). On-line dialysis coupled to liquid chromatography for the automated determination of verapamil and its demethylated metabolite in plasma, chapitre "biomedical analysis with hyphenated chromatography". In Hyphenated techniques in chromatography and hyphenated chromatographic analysers. K.V.C.V.

Crommen, J., Chiap, P., Ceccato, A., & Hubert, P. (1996). Analytical technologies and tolls for drug purity testing [Paper presentation]. IIIrd EUFEPS Conference, Nuremberg, Germany.

Ceccato, A., Toussaint, B., Miralles, B., Chiap, P., Hubert, P., & Crommen, J. (1996). On-line dialysis coupled to liquid chromatography for the automated determination of oxprenolol enantiomers in human plasma [Poster presentation]. VIIth International Symposium on Pharmaceutical and Biomedical Analysis, Osaka, Japan.

Fillet, M., Bechet, I., Ceccato, A., Hubert, P., & Crommen, J. (1995). Enantioseparations of basic compounds by capillary electrophoresis using neutral and anionic cyclodextrins [Poster presentation]. VIth International Symposium on Pharmaceutical and Biomedical Analysis, Saint Louis, United States.

Streel, B., Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1995). Injection-generated solvent and pH gradients for sample enrichment on injection of large volumes in microclumn liquid chromatography. Biomedical Chromatography: BMC, 9, 254-256.
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Streel, B., Hubert, P., Ceccato, A., Chiap, P., & Crommen, J. (1995). Determination of phenothiazines by microcolumn liquid chromatography using injection-generated gradient techniques for sample enrichment. Journal de Pharmacie de Belgique, 50, 398.
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Ceccato, A., Hubert, P., Streel, B., Bechet, I., & Crommen, J. (1995). Enantiomeric separaiton of sotalol and other B-blockers on a chiral-AGP column using aliphatic carboxylic acids as ionic modifiers. Journal de Pharmacie de Belgique, 50, 319.
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Streel, B., Hubert, P., Ceccato, A., Chiap, P., & Crommen, J. (1995). Injection-generated solvent and pH gradients for sample enrichment on injection of large volumes in microcolumn liquid chromatography [Poster presentation]. Symposium «Miniaturisering in vloeistofchromatografie versus capillaire elektroforese», Gand, Belgium.

Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1995). Automated solid-phase extraction coupled to HPLC for the determination of drugs in biological fluids. Pharmacy World and Science, 17, 5.
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Chiap, P., Hubert, P., Ceccato, A., Fillet, M., & Crommen, J. (1995). Automated HPLC analysis of molsidomine and two of its metabolites in human plasma using solid phase extraction as sample preparation. Journal de Pharmacie de Belgique, 50, 320.
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Hubert, P., Chiap, P., Ceccato, A., Bechet, I., & Crommen, J. (1995). Automated determination of camazepam in human plasma by solid phase extraction coupled to HPLC. Journal de Pharmacie de Belgique, 50, 341.
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Chiap, P., Hubert, P., Ceccato, A., Toussaint, B., & Crommen, J. (1995). Comparison of solid-phase extraction and dialysis as on-line sample preparation procedures for the automated HPLC determination of verapamil and norverapamil in human plasma. Journal de Pharmacie de Belgique, 50, 321.
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Toussaint, B., Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1995). On-line combination of dialysis and liquid chromatography for the automated determination of oxprenolol in human plasma. Journal de Pharmacie de Belgique, 50, 403.
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Hubert, P., Chiap, P., Ceccato, A., Fillet, M., & Crommen, J. (1995). Automated determination of acetylsalicylic, salicylic and salicyluric acids in human plasma using solid-phase extraction and HPLC. Journal de Pharmacie de Belgique, 50, 341.
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Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1995). Validation of bioanalytical methods. Journal de Pharmacie de Belgique, 50, 290.
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Ceccato, A., Hubert, P., Toussaint, B., Chiap, P., & Crommen, J. (1995). Automated determination of verapamil and norverapamil in human plasma by high performance chromatography using dialysis as on-line sample preparation technique [Poster presentation]. XIXth International Symposium on Column Liquid Chromatography and Related Techniques, Innsbruck, Austria.

Hubert, P., Chiap, P., Ceccato, A., Streel, B., & Crommen, J. (1995). Determination of several benzodiazepines in plasma using automated solid-phase extraction coupled to high performance chromatography [Poster presentation]. XIXth International Symposium on Column Liquid Chromatography and Related Techniques, Innsbruck, Austria.

Crommen, J., Fillet, M., Bechet, I., Ceccato, A., & Hubert, P. (1994). Chiral separations of basic drugs in capillary electrophoresis using cyclodextrin derivatives as chiral selectors [Paper presentation]. Vth International Symposium on Chiral Discrimination, Stockholm, Sweden.

Ceccato, A., Hubert, P., Streel, B., Bechet, I., & Crommen, J. (1993). Evaluation of an alpha 1-acid glycoprotein chiral stationary phase for the enantioseparation of -blocking drugs [Poster presentation]. 17th International Symposium on Column Chromatography, Hamburg, Germany.

Bechet, I., Paques, P., Ceccato, A., Hubert, P., & Crommen, J. (1993). Analysis of basic drugs by capillary zone electrophoresis [Poster presentation]. 17th International Symposium on Column Chromatography, Hamburg, Germany.

Ceccato, A., Hubert, P., Streel, B., Bechet, I., & Crommen, J. (1993). HPLC enantiomeric separation of B-blocking drugs using an alpha 1-acid glycoprotein column. Journal de Pharmacie de Belgique, 48, 113.
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Crommen, J., Bechet, I., Paques, P., Ceccato, A., & Hubert, P. (1993). Method developement and applications of capillary electrophoresis in drug analysis [Paper presentation]. IVth International Symposium on Pharmaceutical and Biomedical Analysis, Baltimore, United States.

Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1993). Fully automated systems for the bioanalysis of drugs and metabolites using solid-phase extraction in combination with liquid chromatography [Paper presentation]. 9th International Symposium on Advances and Applications of Chromatography in Industry, Bratislava, Slovakia.

Ceccato, A., Hubert, P., Bechet, I., & Crommen, J. (1992). Optimization of separation and sensitivity in the analysis of amino acids by capillary zone electrophoresis and indirect UV detection [Poster presentation]. XIXth International Symposium on Chromatography, Aix en Provence, France.

Bechet, I., Hubert, P., Ceccato, A., & Crommen, J. (1992). Automatic determination of diltiazem and desacetyldiltiazem in human plasma using liquid-solid extraction on disposable cartridges coupled to HPLC [Paper presentation]. Vth Symposium on Handling of Environmental and Biological Samples in Chromatography, Baden-Baden, Germany.

Bechet, I., Ceccato, A., Hubert, P., Herné, P., & Crommen, J. (1992). Determination of Meprobamate in Pharmaceutical Dosage Forms Also Containing Carbromal by Liquid Chromatography and Indirect Photometric Detection. Journal of Pharmaceutical and Biomedical Analysis, 10 (10-12, Oct-Dec), 995-9. doi:10.1016/0731-7085(91)80110-U
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Ceccato, A., Hubert, P., Bechet, I., & Crommen, J. (1992). Enantiomeric separation of basic drugs on an ovomucoid column. Journal de Pharmacie de Belgique, 47, 249.
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Hubert, P., Chiap, P., Ceccato, A., Bechet, I., Sibenaler-Dechamps, R., Maes, P., & Crommen, J. (1992). Determination of verapamil and norverapamil in human plasma by liquid chromatography: comparison between a liquid-liquid extraction procedure and an automated liquid-solid extraction method for sample preparation. Journal of Pharmaceutical and Biomedical Analysis, 10 (10-12), 937-42. doi:10.1016/0731-7085(91)80102-F
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Hubert, P., Chiap, P., Ceccato, A., & Crommen, J. (1992). HPLC determination of propranolol, verapamil and norverapamil in plasma using automated liquid-solid extraction and fluorometric detection. Journal de Pharmacie de Belgique, 47, 196.
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Bechet, I., Ceccato, A., Hubert, P., & Crommen, J. (1992). Separation and quantitative analysis of amino acids by capillary zone electrophoresis with indirect photometric detection. Journal de Pharmacie de Belgique, 47, 181.
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