Article (Scientific journals)
Influence of breathing pattern and lung inflation on impulse oscillometry measurements in horses.
Van Erck, Emmanuelle; Votion, Dominique; Kirschvink, Nathalie et al.
2004In Veterinary Journal, 168 (3), p. 259-69
Peer Reviewed verified by ORBi
 

Files


Full Text
VanErckE_VetJ_2004.pdf
Publisher postprint (305.21 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Pulmonary function test; Forced oscillations; Impulse oscillometry; Horse; Breathing pattern
Abstract :
[en] The objective of this paper was to determine if changes in ventilation patterns could influence the outcome of respiratory function measurements performed with our impulse oscillometry system (IOS) in horses. In a first study, IOS tests were performed in vitro on six isolated equine lungs. Lung inflation levels were controlled by modifying depressurisation inside an artificial thorax and different ventilation patterns were imposed. In a second in vivo study, transient variations in breathing pattern were evaluated both with the IOS and a current reference technique (CRT) in five healthy mature horses after an intravenous (i.v.) injection of lobeline hydrochloride. In both studies, respiratory rate (RR, range: 7-42 breaths/min.) and tidal volume (V(T), range: 0.4-25 L) had minor or no influence on IOS parameters. The influence of lung inflation, most marked for resistance at 5 Hz (R(5 Hz)), was limited for the considered physiological range. In vivo, statistical models indicated that maximal changes in pleural pressure (Max Delta Ppl) and peak flows were the main determinants of the variability of the resistance (R(rs)) and the reactance (X(rs)) of the respiratory system. The fourfold increase in baseline Max Delta Ppl and peak flows obtained during hyperpnoea caused a significant increase in R(rs) at 5 and 10 Hz and a decrease in X(rs) at all frequencies. We conclude that IOS parameters are not influenced by tachypnoea, but will reflect alterations in respiratory mechanics caused by hyperpnoeic breathing
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Veterinary medicine & animal health
Author, co-author :
Van Erck, Emmanuelle ;  Université de Liège - ULiège > Faculté de Médecine vétérinaire, Physiologie
Votion, Dominique  ;  Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux
Kirschvink, Nathalie;  Université de Liège - ULiège
Genicot, B.;  Limburgs Universitair Centrum, Diepenbeek, Belgium > Department of Biostatistics
Lindsey, J.;  Limburgs Universitair Centrum, Diepenbeek, Belgium > Department of Biostatistics
Art, Tatiana ;  Université de Liège - ULiège > Département de sciences fonctionnelles > Phys. neuro-muscul., de l'effort - Méd. sport. des animaux
Lekeux, Pierre ;  Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie - Doyen de la Faculté de Médecine vétérinaire
Language :
English
Title :
Influence of breathing pattern and lung inflation on impulse oscillometry measurements in horses.
Publication date :
2004
Journal title :
Veterinary Journal
ISSN :
1090-0233
eISSN :
1532-2971
Publisher :
Elsevier
Volume :
168
Issue :
3
Pages :
259-69
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 27 March 2009

Statistics


Number of views
63 (5 by ULiège)
Number of downloads
3 (3 by ULiège)

Scopus citations®
 
11
Scopus citations®
without self-citations
8
OpenCitations
 
8

Bibliography


Similar publications



Contact ORBi