Tumor-induced osteomalacia: The tumor may stay hidden!

[en] We report the case of a patient with severe muscular and articular tenderness that caused almost complete immobility. This subject had severe hypophosphatemia due to hyperphosphaturia. Fibroblast growth factor 23 (FGF-23) was abnormally high and the diagnostic of tumor-induced osteomalacia was made. Despite multiple tests, the tumor was not localized. In this report, we discuss different possible investigations to localize the tumor. Lastly, we review the potential therapy available when tumor is not found and can thus not be excised.

Disciplines :

Laboratory medicine & medical technology

Author, co-author :

VAN DER REST, Catherine

CAVALIER, Etienne ; Centre Hospitalier Universitaire de Liège - CHU > Chimie médicale

KAUX, Jean-François ; Centre Hospitalier Universitaire de Liège - CHU > Médecine de l'appareil locomoteur

KRZESINSKI, Jean-Marie ; Centre Hospitalier Universitaire de Liège - CHU > Néphrologie

HUSTINX, Roland ; Centre Hospitalier Universitaire de Liège - CHU > Médecine nucléaire

REGINSTER, Jean-Yves ; Centre Hospitalier Universitaire de Liège - CHU > Médecine de l'appareil locomoteur

DELANAYE, Pierre ; Centre Hospitalier Universitaire de Liège - CHU > Néphrologie

Language :

English

Title :

Tumor-induced osteomalacia: The tumor may stay hidden!

Publication date :

October 2011

Journal title :

Clinical Biochemistry

ISSN :

0009-9120

eISSN :

1873-2933

Publisher :

Elsevier Science, Tarrytown, United States - New York

Volume :

Issue :

14-15

Pages :

1264-6

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 08 September 2011

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Bibliography

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