Article (Scientific journals)
Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use
Hazes, Johanna M.W.; Coulie, Pierre G.; Geenen, Vincent et al.
2011In Rheumatology
Peer Reviewed verified by ORBi
 

Files


Full Text
Rheumatology-2011-Hazes-rheumatology_ker302.pdf
Author postprint (393.2 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Pregnancy; Rheumatoid arthritis; Disease activity; Pregnancy outcome; Drug treatment; Anti-TNF
Abstract :
[en] It has long been known that pregnancy and childbirth have a profound effect on the disease activity of rheumatic diseases. For clinicians, the management of patients with RA wishing to become pregnant involves the challenge of keeping disease activity under control and adequately adapting drug therapy during pregnancy and post-partum. This article aims to summarize the current evidence on the evolution of RA disease activity during and after pregnancy and the use of anti-rheumatic drugs around this period. Of recent interest is the potential use of anti-TNF compounds in the preconception period and during pregnancy. Accumulating experience with anti-TNF therapy in other immune-mediated inflammatory diseases, such as Crohn’s disease, provides useful insights for the use of TNF blockade in pregnant women with RA, or RA patients wishing to become pregnant.
Disciplines :
Endocrinology, metabolism & nutrition
Rheumatology
Immunology & infectious disease
Author, co-author :
Hazes, Johanna M.W.;  Erasmus Universiteit Rotterdam - EUR > Medicine > Rheumatology
Coulie, Pierre G.;  Université Catholique de Louvain - UCL > de Duve Institute
Geenen, Vincent ;  Université de Liège - ULiège > Centre d'immunologie
Vermeire, Severine;  Katholieke Universiteit Leuven - KUL > Gastroenterology
Carbonnel, Franck;  Hôpital Bicêtre > Gastroentérologie
LOUIS, Edouard  ;  Centre Hospitalier Universitaire de Liège - CHU > Gastro-Entérologie-Hépatologie
Masson, Pierre;  Université Catholique de Louvain - UCL > de Duve Institute
De Keyser, Filip;  Ghent University > Rheumatology
Language :
English
Title :
Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use
Publication date :
September 2011
Journal title :
Rheumatology
ISSN :
1462-0324
eISSN :
1462-0332
Publisher :
Oxford University Press, Oxford, United Kingdom
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
Available on ORBi :
since 07 September 2011

Statistics


Number of views
147 (3 by ULiège)
Number of downloads
173 (0 by ULiège)

Scopus citations®
 
99
Scopus citations®
without self-citations
99
OpenCitations
 
94

Bibliography


Similar publications



Contact ORBi