Article (Scientific journals)
Cellules Tumorales Circulantes : détection, caractérisation et intérêts cliniques
Gilles, Christine; COLLIGNON, Joëlle; Noël, Agnès et al.
2011In Revue Médicale de Liège, 66 (5-6), p. 279-84
Peer reviewed
 

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Keywords :
Circulating tumor Cells (CTCs); Disseminated Tumor Cells (DTCs); Breast cancer
Abstract :
[en] The metastatic process generates circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) in bone marrow and other organs which can remain as occult metastases. Various methods and systems have been developed to allow the isolation and identification of those cells but major technical limitations still exist. Research on CTCs is a nevertheless tremendously growing field of cancer research because of their potential clinical applications. CTCs indeed convey predictive information for the development of metastasis and recurrence, and prognostic information regarding patient survival. CTCs enumeration could also be used to monitor the effectiveness of adjuvant treatments. Moreover, enhancing our basic understanding of the metastatic process, CTCs, and DTCs in particular, are thought to contain subpopulations of cells with stem cells properties that would be responsible for relapses.
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Oncology
Author, co-author :
Gilles, Christine ;  Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement
COLLIGNON, Joëlle  ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Noël, Agnès ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie cellulaire et moléculaire appliquée à l'homme
Jerusalem, Guy  ;  Université de Liège - ULiège > Département des sciences cliniques > Oncologie
Foidart, Jean-Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique
Language :
French
Title :
Cellules Tumorales Circulantes : détection, caractérisation et intérêts cliniques
Alternative titles :
[en] Circulating tumor cells: detection, characterization and clinical impact
Publication date :
2011
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Hopital de Baviere, Liège, Belgium
Volume :
66
Issue :
5-6
Pages :
279-84
Peer reviewed :
Peer reviewed
Available on ORBi :
since 23 June 2011

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