Reference : Structure of the cell wall of Micrococcus lysodeikticus. I. Study of the structure of...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Structure of the cell wall of Micrococcus lysodeikticus. I. Study of the structure of the glycan
Leyh-Bouille, Mélina [Université de Liège - ULiège > > > > Service de Bactériologie > >]
Ghuysen, Jean-Marie [Université de Liège - ULiège > > > Service de Bactériologie > >]
Tipper, Donald J. [University of Wisconsin > Department of Pharmacology > > >]
Stominger, Jack L. [University of Wisconsin > Department of Pharmacology > > >]
American Chemical Society
Yes (verified by ORBi)
[en] amino sugars ; cell wall ; chromatography ; glucosamine ; glycoside hydrolases ; micrococcus ; muramidase ; myxomycetes ; oligosaccharides ; periodic acid ; polysaccharides ; paper ; cytology ; analysis ; enzymology ; bacterial
[en] The glycan portion of the cell wall of Micrococcus lysodeikticus, or at least the greatest part of it, consists of linear chains of alternating N-acetyl-glucosamine and N-acetylmuramic acid residues, both in the pyranose ring form. Both glycosidic links are 1,4.
The links from N-acetylglucosamine to N-acetyl-muramic acid and probably the links from N-acetyl-muramic acid to N-acetylglucosamine are in the β configuration. At least 40% of the N-acetylmuramic residues are not substituted by peptide. This structure is based on the quantitative isolation of the disaccharides N-acetylglucosaminyl-β-1,4-N-acetylmuramic acid and N-acetylmuramyl-(β?)-l,4-N-acetylglucosamine, of the trisaccharides N-acetylglucosaminyl-β-l,4-N-acetyl-muramyl-(β?)-1,4-N-acetylglucosamine and N-acetyl-muramyl-(β?)-1,4-N-acetylglucosaminyl-β-1,4-N-acetyl-muramic acid, and of the tetrasaccharide N-acetylglucos-aminyl-β-1,4-N-acetylmuramyl-(β?)-l,4-N-acetylglucos-aminyl-β-l,4-N-acetylmuramic acid. An octasaccharide the structure of which has not been fully elucidated has also been isolated.
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