Reference : Le medicament du mois. Le tiotropium (SPIRIVA)
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
Le medicament du mois. Le tiotropium (SPIRIVA)
Corhay, Jean-Louis mailto [Centre Hospitalier Universitaire de Liège - CHU > Pneumologie-Allergologie > > >]
Louis, Renaud mailto [Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie]
Revue Médicale de Liège
Yes (verified by ORBi)
[en] SPIRIVA (tiotropium) is a long-acting anticholinergic bronchodilatator, inhaled once a day, which produces relaxation of airway smooth muscle through antagonism of acetylcholine at M3-muscarinic receptors. Its duration of action is at least 24h with once daily administration of tiotropium. Several studies have shown its efficacy and its good tolerance in the treatment of patients who are suffering from moderate to very severe chronic obstructive pulmonary disease (COPD). SPIRIVA improves spirometric measurements and quality of life, and reduces dyspnea and exacerbation rate in COPD patients.

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