Article (Scientific journals)
Recurrent pancreatitis in mitochondrial cytopathy.
DEBRAY, François-Guillaume; Drouin, Eric; Herzog, Denise et al.
2006In American Journal of Medical Genetics. Part A, 140 (21), p. 2330-5
Peer Reviewed verified by ORBi
 

Files


Full Text
Recurrent pancreatitis.pdf
Publisher postprint (160.59 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Acute Disease; Adolescent; DNA Mutational Analysis; DNA, Mitochondrial/genetics; Humans; Kearns-Sayre Syndrome/complications/genetics; Male; Pancreatic Pseudocyst/complications/radiography; Pancreatitis/complications/radiography; Recurrence; Sequence Deletion; Tomography, X-Ray Computed
Abstract :
[en] Diabetes mellitus and exocrine insufficiency are the commonest pancreatic manifestations of mitochondrial diseases. In contrast, pancreatitis has rarely been described in mitochondrial syndromes. We report on a patient with Kearns-Sayre syndrome and recurrent episodes of acute pancreatitis for which no explanation could be found other than the associated mitochondrial dysfunction. Interestingly, pharmacological disruption of mitochondrial metabolism in various models as well as in patients can cause pancreatitis, further supporting this association. A diagnosis of pancreatitis should be considered in any patients with mitochondrial disease and recurrent abdominal pain.
Disciplines :
Genetics & genetic processes
Author, co-author :
DEBRAY, François-Guillaume 
Drouin, Eric
Herzog, Denise
Lortie, Anne
Lambert, Marie
Garel, Laurent
Mitchell, Grant A
Michaud, Jacques L
Language :
English
Title :
Recurrent pancreatitis in mitochondrial cytopathy.
Publication date :
2006
Journal title :
American Journal of Medical Genetics. Part A
ISSN :
1552-4825
eISSN :
1552-4833
Publisher :
Wiley Liss, Inc., Hoboken, United States - New Jersey
Volume :
140
Issue :
21
Pages :
2330-5
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 March 2011

Statistics


Number of views
50 (0 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
18
Scopus citations®
without self-citations
18
OpenCitations
 
15

Bibliography


Similar publications



Contact ORBi