Collagen; Connective tissu; Bone marrow; Hematopoietic microenvironment
Abstract :
[en] mmunofluorescent staining of frozen sections of rat bone marrow for collagen types I and III revealed the presence of a distinctive, collagen-producing cell type. Morphologically, these cells closely resembled reticular cells. They were large, with branching cytoplasm and were closely related to an extensive intercellular matrix of collagenous material that surrounded the hematopoietic cells of the marrow. Biochemical studies demonstrated synthesis of collagen types I and III, in a ratio of 4:1, by fresh rat bone marrow cells.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Bentley, S. A.
Foidart, Jean-Michel ; Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique
Kleinman, H. K.
Language :
English
Title :
Connective tissue elements in rat bone marrow: immunofluorescent visualization of the hematopoietic microenvironment.
Publication date :
1984
Journal title :
Journal of Histochemistry and Cytochemistry
ISSN :
0022-1554
eISSN :
1551-5044
Publisher :
Histochemical Society, New York, United States - New York