Glucosamine sulphate in osteoarthritis: from symptoms to structure modification

Several chemical entities have been carefully investigated for the symptomatic and structural management of osteoarthritis. The most compelling evidence of a potential for inhibiting the structural progression of osteoarthritis has been obtained with glucosamine sulfate. At any rate, this compoind has clearly demonstrated a symptomatic action, mainly in osteoarthritis of the lower limbs, on pain relief an improvement of functional disability. An important issue is that all the conclusive studies with such chyemical entities resulted from the use of prescription medicines and not over-the-counter pills of food supplements.