[en] INTRODUCTION: The semicircular lipoatrophy of the thighs is a disorder whose incidence remained rare for years. Only recently, an "epidemic" situation emerged, affecting hundreds of subjects who shared a status of administrative employee. OBSERVATION: The older etiopathogenic hypotheses give way to a newer one implying the electromagnetic fields generated by computers and their wirings. The resulting modifications in the intrinsic bioelectrical properties of the skin could influence the biology of macrophages exhibiting lipophagic activity in the hypodermis. The electroactivation of these cells could lead to TNF-alpha release. DISCUSSION: The semicircular lipoatrophy of the thighs is a problem that may affect an employee out of two. Rather than hoping an efficaceous drug therapy, prevention must be advocated by adapting the work conditions related to the use of computerized devices.
Disciplines :
Dermatology
Author, co-author :
Flagothier, Caroline ; Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
Quatresooz, Pascale ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Pierard, Gérald ; Université de Liège - ULiège > Département des sciences cliniques > Dermatopathologie
Language :
French
Title :
Lipolyse electromagnetique et lipoatrophie semi-circulaire des cuisses
Alternative titles :
[en] Electromagnetic Lipolysis and Semicircular Lipoatrophy of the Thighs
Gschwandtner WR, Münzberger H. Lipoatrophia semicircularis. Ein Beitrag zu bandförming-curculären Atrophien des subcutanene Fettgewebes im Extremitätenbereich. Der Hautartz 1974;25:222-7.
Schnitzler L, Verret JL, Titon JP. La lipoatrophie semi-circulaire des cuisses. Ann Dermatol Venereol 1980;107:421-6.
Ayale F, Lembo G, Ruggiero F, Balato N. Lipoatrophia semicircularis, report of a case. Dermatology 1985;170:101-3.
Pibouin M, Laudren A, Mignard MH, Chevrant-Breton J. Lipoatrophie semi-circulaire des cuisses. À propos d'un cas. Revue de la littérature. Sem Hop Paris, 1986;62:3760-2.
Nagore E, Sanchez-Motilla JM, Rodriguez-Serna M, Vilata JJ, Aliaga A. Lipoatrophia semicircularis - a traumatic panniculitis: report of seven cases and review of the literature. J Am Acad Dermatol 1998;39:879-81.
Hodak E, David M, Sandbank M. Semicircular lipoatrophy - a pressure induced lipoatrophy? Clin Exp Dermatol 1990;15:464-5.
De Groot AC. Is lipoatrophia semicircularis induced by pressure? Br J Dermatol 1994;131:887-90.
Hermans V, Hautekiet M, Haex B, Spaepen AJ, Van der Perre G. Lipoatrophia semicircularis and the relation with office work. Appl Ergon 1999;30:319-24.
Mascaro JM, Ferrando J. The perils of wearing jeans: lipoatrophia semicircularis. Int J Dermatol 1983;22:333.
Sénéchal S, Victor V, Choudat D, Hornez-Davin, Conso F. Semicircular lipoatrophy: 18 cases in the same company. Contact Dermatitis 2000;42:101-2.
Lachapelle JM, Tennstedt D. Nouvelles dermatoses de l'environnement. Dans : Progrès en dermato-allergologie. Dijon 2002. Ed. par E. Collet. John Libbey Eurotext, Montrouge, 2002, pp. 157-165.
Maes A, Curvers B, Verschaeve L. Lipoatrophia semicircularis: an electromagnetic hypothesis. Electromagn Biol Med 2003;22:183-93.
Anonyme. Les «cuisses striées» à l'étude. Travail et bien-être 2000;4:28-33.
Dahl PR, Zalla MJ, Winkelmann RK. Localized involutional lipoatrophy: a clinicopathologic study of 16 patients. J Am Acad Dermatol 1996;35:523-8.
Petruschke Th, Hauner H. Tumor necrosis factor-α prevents the differentiation of human adipocyte precursor cells and causes delipidation of newly developed fat cells. J Clin Endocrinol Metab 1993;76:742-7.
Prins JB, Niesler CU, Winterford CM, Bright NA, Siddle K, O'Rahilly S, Walker NI, Cameron DP. Tumor necrosis factor induces apoptosis of human adipose cells. Diabetes 1997;46:1939-44.
Pessina GP, Aldinucci C. Pulsed electromagnetic fields enhance the induction of cytokines by peripheral blood mononuclear cells challenged with phytohemagglutinin. Bioelectromagnetics 1998;19:445-51.
Piérard GE, Nizet JL, Piérard-Franchimont C. Cellulite: from standing fat herniation to hypodermal stretch marks. Am J Dermatopathol 2000;22:34-7.
Piérard-Franchimont C, Piérard GE, Henry F, Vroome V, Cauwenbergh G. A randomized, placebo-controlled trial of topical retinol to mitigate cellulite. Am J Clin Dermatol 2000;1:369-74.