[en] The bedside diagnosis of vegetative and minimally conscious patients is extremely challenging, and prediction of individual
long-term outcome remains difficult. State-of the art neuroimaging methods could help disentangle complex cases and offer new prognostic
criteria. These methods can be divided into to three categories: First, new anatomical MRI neuroimaging methods, like diffusion
tensor imaging (DTI) or spectroscopy, and passive functional imaging methods (looking at the brain’s activation induced by external
stimuli), could provide new diagnostic and prognostic markers. Second, neuroimaging methods based on active collaboration from the
patient could help to detect clinically unnoticed signs of consciousness. Third, developments in brain-computer interfaces based on EEG,
functional MRI, or EMG offer communication possibilities in brain-damaged patients who can neither verbally nor nonverbally express
their thoughts or wishes. These new approaches raise important issues not only from a clinical and ethical perspective (i.e., patients’
diagnosis, prognosis and management) but also from a neuroscientific standpoint, as they enrich our current understanding of the emergence
and function of the conscious human mind.
Research Center/Unit :
Coma Science Group GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège
Disciplines :
Neurology
Author, co-author :
Noirhomme, Quentin ; Université de Liège - ULiège > Centre de recherches du cyclotron
Soddu, Andrea ; Université de Liège - ULiège > Centre de recherches du cyclotron
Lehembre, Remy ; Université de Liège - ULiège > Centre de recherches du cyclotron
Bruno, Marie-Aurélie ; Université de Liège - ULiège > Centre de recherches du cyclotron
Gosseries, Olivia ; Université de Liège - ULiège > Centre de recherches du cyclotron
Demertzi, Athina ; Université de Liège - ULiège > Centre de recherches du cyclotron
Maudoux, Audrey ; Université de Liège - ULiège > Centre de recherches du cyclotron
Schnakers, Caroline ; Université de Liège - ULiège > Centre de recherches du cyclotron
Boveroux, Pierre ; Université de Liège - ULiège > Anesthésie et réanimation
Boly, Mélanie ; Université de Liège - ULiège > Département des sciences cliniques > Neurologie
Laureys, Steven ; Université de Liège - ULiège > Centre de recherches du cyclotron - Département des sciences cliniques
Language :
English
Title :
Functional Neuroimaging Approaches to the Changing Borders of Consciousness
Publication date :
2010
Journal title :
Journal of Psychophysiology
ISSN :
0269-8803
Publisher :
Hogrefe & Huber, Seattle, United States - Washington
Volume :
24
Issue :
2
Pages :
68-75
Peer reviewed :
Peer reviewed
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique EC - European Commission JSMF - James S McDonnell Foundation MSF - Mind Science Foundation French-Speaking Community of Belgium FMRE - Fondation Médicale Reine Elisabeth ULg - University of Liège
Funding text :
This research was funded by the Belgian National Funds for Scientific Research (FNRS), the European Commission (DISCOS, COST, Mindbridge, DECODER), the James McDonnell Foundation, the Mind Science Foundation, the French Speaking Community Concerted Research Action, the Foundation Médicale Reine Elisabeth, and the University of Liège.
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