[en] Sexually transmitted diseases (STD) are a major public health problem because their incidence is increasing worldwide despite prevention campaigns and because they raise the risk of HIV infection. Anorectal localisations of STD are common among men who have sex with men (MSM) but can also be seen among heterosexuals (men or women). Transmission of such infections is due to anal sex or to other sexual behaviours like "fisting". Although some pathogens (like Human Papillomavirus-HPV) are common in gastroenterologist/proctologist consultations, others are not so well-known. Furthermore during the last years, sexual risky behaviours have led to resurgence of old affections (like syphilis) or to emergence of unknown diseases (like lymphogranuloma venereum) in our countries. This presentation tends to focus on clinical manifestation, diagnosis and treatment of different STD: HPV, Herpes Simplex Virus, Neisseria gonorrhoeae, Chlamydia trachomatis (in particularly lymphogranuloma venereum) and Treponema pallidum.
Disciplines :
Gastroentérologie & hépatologie
Auteur, co-auteur :
Van Kemseke, Catherine ; Centre Hospitalier Universitaire de Liège - CHU > Gastro-Entérologie-Hépatologie
SASSE, A., DEFRAYE, A., DUCOFFRE, G., Recent syphilis trends in Belgium and enhancement of STI surveillance systems (2004) Euro Surveill, 9, pp. 6-8
VANDENBRUAENE M., OSTYN B., CRUCITTI T., SASSA A., SERGEANT M., VAN DYCK E., VAN ESBROECK M., MOERMAN F. Lymphogranuloma venereum outbreak in men who have sex with men (MSM) in Belgium, January 2004 to July 2005. Euro Surveill., 2005, 10 (9) : E050929.3
BARRETT, W.L., CALLAHAN, T.D., ORKIN, B.A., Perianal manifestations of human immunodeficiency virus infection : Experience with 260 patients (1998) Dis. Colon Rectum, 41, pp. 606-611. , discussion 611-2
FLEISCHER, A.B., PARRISH, C.A., GLENN, R., FELDAMN, S.R., Condylomata acuminata (genital warts) : Patient demographics and treating physicians (2001) Sex. Transm. Dis, 28, pp. 643-647
CONLEY, L.J., ELLERBROCK, T.V., BUSH, T.J., CHIASSON, M.A., SAWO, D., WRIGHT, T.C., HIV-1 infection and the risk of vulvovaginal and perianal condylomata acuminata and intra-epithelial neoplasia : A prospective cohort study (2002) Lancet, 359, pp. 108-113
SULTAN, S., Aspect clinique des lesions anales à HPV. (2003) Le Courrier de Coloproctologie, 1 (SUPPL.), pp. 8-9
PALEFSKY, J.M., Anal human papillomavirus infection and anal cancer in HIV-positive individuals : An emerging problem (1994) AIDS, 8, pp. 283-285
PALEFSKY, J.M., HOLLY, E.A., RALSTON, M.L., JAY, N., BERRY, J.M., DARRAGH, T.M., High incidence of anal high-grade squamous intraepithelial lesions among HIV-positive and HIV-negative homosexual and bisexual men (1998) AIDS, 12, pp. 495-503
ABRAMOWITZ, L., BENABDERRAHMANE, D., RAVAUD, P., WALKER, F., RIOUX, C., JESTIN, C., BOUVET, E., DUVAL, X., Anal squamous intraepithelial lesions and condyloma in HIV-infected heterosexual men, homosexual men and women : Prevalence and associated factors (2007) AIDS, 21, pp. 1457-1465
Clinical Management Guidelines for Obstetrician-Gynecologists. Number 61, April, 2005. Human papillomavirus (2005) Obstet. Gynecol, 105, pp. 905-918. , ACOG PRACTICE BULLETIN
JABLONSKA, S., Traditional therapies for the treatment of condylomata acuminata (genital warts) (1998) Australas J. Dermatol, 39 (SUPPL. 1), pp. S2-S4
SULTAN S. Maladies rectales sexuellement transmissibles. In: SIPROUDHIS L., PANIS Y., BIGARD M.A. (eds). Traité des maladies de l'anus et du rectum. Elsevier-Masson, Paris, 2006, p 97-108
PUY-MONTBRUN, T., GANANSIA, R., DENIS, J., Maladies sexuellement transmissibles anorectales (SIDA exclu) (1999) Proctologie pratique, pp. 153-161. , DENIS J, GANANSIA R, PUY-MONTBRUN T, eds, Masson, Paris
SEN, P., BARTON, S.E., Genital herpes and its management (2007) BMJ, 334, pp. 1048-1052
CHOUDHURY, B., RISLEY, C.L., GHANI, A.C., BISHOP, C.J., WARD, H., FENTON, K.A., ISON, C.A., SPRATT, B.G., Identification of individuals with gonorrhoea within sexual networks : A population study (2006) Lancet, 368, pp. 139-146
SHERRARD, J., BARLOW, D., Gonorrhoea in men : Clinical and diagnosis aspects (1996) Genitourin. Med, 72, pp. 422-426
LEWIS, J.S., FAKILE, O., FOSS, E., LEGARZA, G., LESKYS, A., LOWE, K., POWNING, D., Direct DNA probe assay for Neisseria gonorrhoeae in pharyngeal and rectal specimens (1993) J. Clin. Microbiol, 31, pp. 2783-2785
Update to CDC's sexually transmitted diseases treatment guidelines, 2006 : Fluoroquinolones no longer recommended for treatment of gonococcal infections (2007) MMWR Morb. Mortal. Wkly. Rep, 56, pp. 332-336. , CENTERS FOR DISEASE CONTROL AND PREVENTION CDC
JONES, R.B., BATTEIGER, B.E., Chlamydia trachomatis (trachoma, perinatal infections, lymphogranuloma venereum and other genital infections) (2000) Principles and Practice of Infectious Diseases, , MANDELL G.L, BENNETT J.E, DOLIN R, eds, 5th ed. Churchill Livingstone, Philadelphia
NIEUWENHUIS, R.F., OSSEWAARDE, J.M., GOTZ, H.M., DEES, J., THIO, H.B., THOMEER, M.G., DEN HOLLANDER, J.C., VAN DER MEIJDEN, W.I., Resurgence of lymphogranuloma venereum in Western Europe : An outbreak of Chlamydia Trachomatis serovar L2 proctitis in the Netherlands among men who have sex with men (2004) Clin. Infect. Dis, 39, pp. 996-1003
GÖTZ, H.M., OSSEWAARDE, J.M., NIEUWENHUIS, R.F., VAN DER MEIJDEN, W.I., DEES, J., THIO, B., DEZWART, O., VAN DE LAAR, M.J., A cluster of lymphogranuloma venereum among homosexual men in Rotterdam with implications for other countries in Western Europe (2004) Ned. Tijdschr. Geneeskd, 148, pp. 441-442
BLANK, S., SCHILLINGER, J.A., HARBATKIN, D., Lymphogranuloma venereum in the industrialised world (2005) Lancet, 365, pp. 1607-1608
MEYER, T., ARNDT, R., VON KROSIGK, A., PLETTENBERG, A., Repeated detection of lymphogranuloma venereum caused by Chlamydia Trachomatis L2 in homosexual men in Hamburg (2005) Sex. Transm. Infect, 81, pp. 91-92
HERIDA, M., SEDNAOUI, P., COUTURIER, E., NEAU, D., CLERC, M., SCIEUX, C., KREPLAK, G., DE BARBEYRAC, B., Rectal lymphogranuloma venereum, France (2005) Emerg. Infect. Dis, 11, pp. 205-206
FARHI, D., DUPIN, N., An outbreak of lymphogranuloma venereum in Western Europe (2005) Rev. Prat, 55, pp. 1747-1750
VAN DER, B.A.K., SPAARGAREN, J., MORRE, S.A., FENNEMA, H.S., MINDEL, A., COUTINHO, R.A., DE VRIES, H.J., Diagnostic and clinical implications of anorectal lymphogranuloma venereum in men who have sex with men : A retrospective case-control study (2006) Clin. Infect. Dis, 42, pp. 186-194
NAU, J.Y., New alert on lymphogranuloma venerum of the rectum (2006) Rev. Med. Suisse, 2, p. 2891
HERIDA, M., DE BARBEYRAC, B., SEDNAOUI, P., SCIEUX, C., LEMARCHAND, N., KREPLAK, G., CLERC, M., SEMAILLE, C., Rectal lymphogranuloma venereum surveillance in France, 2004-2005 (2006) Euro. Surveill, 11, pp. 155-156
HALIOUA, B., BOHBOT, J.M., MONFORT, L., NASSAR, N., DE BARBEYRAC, B., MONSONEGO, J., SEDNAOUI, P., Anorectal lymphogranuloma venereum : 22 cases reported in a sexually transmitted infections center in Paris (2006) Eur. J. Dermatol, 16, pp. 177-180
PATHELA, P., BLANK, S., SCHILLINGER, J.A., Lymphogranuloma venereum : Old pathogen, new story (2007) Curr. Infect. Dis. Rep, 9 (2), pp. 143-150
WARD, H., MARTIN, I., MAC DONALD, N., ALEXANDER, S., SIMMS, I., FENTON, K., FRENCH, P., ISON, C., Lymphogranuloma venereum in the United Kingdom (2007) Clin. Infect. Dis, 44, pp. 26-32
STARK, D., VAN HAL, S., HILLMAN, R., HARKNESS, J., MARRIOTT, D., Lymphogranuloma venereum in Australia : Anorectal Chlamydia trachomatis serovar L2b in MSM (2007) J. Clin. Microbiol, 45, pp. 1029-1031
VAN HAL, S.J., HILLMAN, R., STARK, D.J., HARKNESS, J.L., MARRIOTT, D., Lymphogranuloma venereum : An emerging anorectal disease in Australia (2007) Med. J. Aust, 187, pp. 309-310
PELGROM, J.M., VOGELAERS, D., COLLE, I., Hepatitis C-seroconversion within three to six months after having contracted clinical syphilis and/or lymphogranuloma venereum rectitis in five homosexually active, HIV seropositive men (2008) Acta Clin. Belg, 63, pp. 335-338
GÖTZ, H.M., VAN DOORNUM, G., NIESTERS, H.G., DEN HOLLANDER, J.G., THIO, H.B., DE ZWART, O., A cluster of acute hepatitis C virus infection among men who have sex with men-results from contact tracing and public health implications (2005) AIDS, 19, pp. 969-974
OOTANI, A., MIZUGUCHI, M., TSUNADA, S., SAKATA, H., IWAKIRI, R., TODA, S., FUJIMOTO, K., Chlamydia Trachomatis proctitis (2004) Gastrointent. Endosc, 60 (1), pp. 161-162
BOSMAN, A., DE ZWART, O., SCHOP, W.A., SCHOOTS, B., VAN DER MEIJDEN, W., CHIN-A-LIEN, R.A., Increase of early syphilis in a red light district in Rotterdam (1995-1997) and preventive treatment (1999) Ned. Tijdschr. Geneeskd, 143, pp. 2324-2328
COUTURIER, E., MICHEL, A., JANIER, M., DUPIN, N., SEMAILLE, C., SYPHILIS SURVEILLANCE NETWORK. Syphilis surveillance in France, 2000-2003 (2004) Euro. Surveill, 9, pp. 8-10
MARCUS, U., BREMER, V., HAMOUDA, O., Syphilis surveillance and trends of the syphilis epidemic in Germany since the mid-90s (2004) Euro. Surveill, 9, pp. 11-14
CRONIN, M., DOMEGAN, L., THORTON, L., FITZGERALD, M., HOPKINS, S., O'LORCAIN, P., CREAMER, E., O'FLANAGAN, D., The epidemiology of infectious syphilis in the Republic of Ireland (2004) Euro. Surveill, 9, pp. 14-17
RIGHARTS, A.A., SIMMS, I., WALLACE, L., SOLOMOU, M., FENTON, K.A., Syphilis surveillance and epidemiology in the United Kingdom (2004) Eur. Surveill, 9, pp. 21-25
COWAN, S., Syphilis in Denmark-outbreak among MSM in Copenhagen, 2003-2004 (2004) Euro. Surveill, 9, pp. 25-27
GONZALES-RUIZ, C., HEARTFIELD, W., BRIGGS, B., VUKASIN, P., BEART, R.W., Anorectal pathology in HIV/AIDS-infected patients has not been impacted by highly active antiretroviral therapy (2004) Dis. Colon Rectum, 47, pp. 1483-1486
SPARLING, P.F., Natural history of syphilis (1990) Sexually Transmitted Diseases, , HOLMES K.K, MARDH P.A, SPARLING P.F. et al, eds, McGraw-Hill, New York, NY
BASSI, O., COSA, G., COLAVOLPE, A., ARGENTIERI, R., Primary syphilis of the rectum : Endoscopic and clinical features. Report of a case (1991) Dis. Colon Rectum, 34, pp. 1024-1026
FURMAN, D.L., PATEL, S.K., ARLUK, G.M., Endoscopic and histologic appearance of rectal syphilis (2008) Gastrointest. Endos, 67, p. 161. , commentary 161-2
CHAPEL, T.A., The signs and symptoms of secondary syphilis (1980) Sex. Transm. Dis, 7, pp. 161-164
CLARK, E.G., DANBOLT, N., The Oslo study of the natural course of untreated syphilis : An epidemiologic investigation based on a re-study of the Boeck-Bruusgaard material : a review and appraisal (1955) J. Chronic. Dis, 2, pp. 311-344
LARSEN, S.A., Syphilis (1989) Clin. Lab. Med, 9, pp. 545-557
CALONGE, N., Screening for syphilis infection recommendation statement (2004) Ann. Fam. Med, 2, pp. 362-365