Article (Scientific journals)
Trenbolone acetate in combination with 17 beta-estradiol: influence of implant supports and dose levels on animal performance and plasma metabolites.
Istasse, Louis; Evrard, Pierre; Van Eenaeme, Christian et al.
1988In Journal of Animal Science, 66 (5), p. 1212-22
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Keywords :
Animals; Body Composition/drug effects; Body Weight/drug effects; Cattle/growth & development; Creatinine/blood; Drug Implants; Estradiol/administration & dosage/pharmacology; Estrenes/pharmacology; Growth Hormone/blood; Male; Trenbolone/administration & dosage/pharmacology; Urea/blood
Abstract :
[en] Twelve (Exp. 1) and 24 (Exp. 2) young growing bulls were used to compare the effects of long-acting, cholesterol-based implants with short-acting, lactose-based implants. Each implant contained 200 mg of trenbolone acetate and 40 mg of 17 beta-estradiol. The long-acting, cholesterol-based implants were applied once either 18 wk (early implantation) or 12 wk (late implantation) before slaughter. The lactose-based pellets were implanted once (6 wk before slaughter), twice (12 and 6 wk) or three times (18, 12 and 6 wk) before slaughter. Treated animals had higher live weight gains, a lower feed conversion ratio, a higher proportion of lean meat and a lower proportion of adipose tissue than control animals. In Exp. 1 live weight gain of bulls implanted early with a single cholesterol-based implant was similar to the gain of animals treated three times with a lactose-based implant, but in Exp. 2 the effects of the long-acting implants given early were not sustained. In Exp. 3, 24 young growing bulls were used in a 3 X 2 factorial design to compare the effects of three dose levels of trenbolone acetate (100, 200 and 300 mg) and two levels of 17 beta-estradiol (40 and 60 mg). There were no significant differences between treatment groups, but highest live weight gains were observed in animals implanted with 300 mg of trenbolone and 60 mg of estradiol. This group also yielded the highest proportion of lean meat and the lowest proportion of adipose tissue. There was a decrease in plasma urea concentration after each implantation. It appeared also that plasma trenbolone was higher with implants containing 60 mg of estradiol. There were no differences between groups in growth hormone response to arginine stimulation.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Istasse, Louis ;  Université de Liège - ULiège > Département de productions animales > Nutrition des animaux domestiques
Evrard, Pierre
Van Eenaeme, Christian 
Gielen, M. P.
Maghuin-Rogister, Guy ;  Université de Liège - ULiège > Département de sciences des denrées alimentaires > Département de sciences des denrées alimentaires
Bienfait, Jean-Marie 
Language :
English
Title :
Trenbolone acetate in combination with 17 beta-estradiol: influence of implant supports and dose levels on animal performance and plasma metabolites.
Publication date :
1988
Journal title :
Journal of Animal Science
ISSN :
0021-8812
eISSN :
1525-3163
Publisher :
American Society of Animal Science, Savoy, United States - Illinois
Volume :
66
Issue :
5
Pages :
1212-22
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 10 March 2009

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