Article (Scientific journals)
Proteins of Bovine Herpesvirus Type 4 Released into the Culture Medium of Productively Infected Cells: Identification of a 135k Glycoprotein Involved in Viral Attachment
Dubuisson, J.; Koromyslov, I.; Pastoret, Paul-Pierre et al.
1992In Journal of General Virology, 73 ((Pt 1)), p. 189-94
Peer Reviewed verified by ORBi
 

Files


Full Text
093pub_thiry.pdf
Author postprint (1.33 MB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] Three bovine herpesvirus type 4 (BHV-4) proteins released into the culture medium of infected cells were identified, with Mr values of 135K, 16K and 14.5K. Among these three proteins, two were precipitated by the monoclonal antibodies characterized in this work. One is a glycoprotein of 135K (gp8) which does not seem to be involved in BHV-4 neutralization. Moreover, this 135K glycoprotein adsorbed onto uninfected susceptible cells. The attachment of gp8 to cells was totally inhibited by the prior adsorption of unlabelled viral proteins. Moreover, anti-gp8 monoclonal antibodies were effective in inhibiting the adsorption of gp8. These results indicate that gp8 could be involved in BHV-4 attachment.
Disciplines :
Microbiology
Veterinary medicine & animal health
Author, co-author :
Dubuisson, J.
Koromyslov, I.
Pastoret, Paul-Pierre ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Département des maladies infectieuses et parasitaires
Thiry, Etienne ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales
Language :
English
Title :
Proteins of Bovine Herpesvirus Type 4 Released into the Culture Medium of Productively Infected Cells: Identification of a 135k Glycoprotein Involved in Viral Attachment
Publication date :
January 1992
Journal title :
Journal of General Virology
ISSN :
0022-1317
eISSN :
1465-2099
Publisher :
Society for General Microbiology, United Kingdom
Volume :
73
Issue :
(Pt 1)
Pages :
189-94
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 05 March 2009

Statistics


Number of views
19 (0 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
7
Scopus citations®
without self-citations
4
OpenCitations
 
6

Bibliography


Similar publications



Contact ORBi